Gene

KWMTBOMO10231

Pre Gene Modal

BGIBMGA000180

Annotation

PREDICTED:_serine/threonine-protein_kinase/endoribonuclease_IRE1_[Amyelois_transitella]

Location

Bomo_Chr17(+):5307882-5335356      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.05 Nuclear   Reliability : 1.072 PlasmaMembrane   Reliability : 1.151

CDS

ATGAAGTTTTTATTATTGATACTATTTCTGCTCGGTTCCTCCGGCTTCGGAACCGTTGTTGATGAAGAGGGAAAGGAAAGCACAGAAATATCCCGTGCTTTGGATGACCGGCCGCTTCTGTTTGCCACGTTAGGAGGCGGTATGGTTGCTGTTGATCCTGTGTCTGGAGACATTATTTGGAAATTAAAAGACGAGCCCGTTGTCAAAGTTCCGAGCCAAGACGCGAACTTGATGCCGCAGTTCCTCCCGGATCCGAGGCATGGATTCCTATACACGTACGGCCCGAGGGGCGACCAGCAAATGTTGAAGAAGCTCCCGTTTACAATACCGGAGCTGGTGGCAAACGCGCCCTGCCGATCTACAGACGGTATTTTGTACACCGGAAAGAAAAGCGATACTTGGTTCATGATTGATCCATTAACCGGCTTTCGTGAGCACGTTTCAGGTTTTGACAAATCGAAAATATTCAAAAGCGACGACGAGAACACTTGCAACTCCGAGAAGAAGAAAGGTATTTACGTGGCGCGTACTGAATACAACATCCTGATGCACGATTCGAAGAATGTAAATCATAAATGGAATGTTACGTTCTTTGATTACACGTCGCTAGCTATGGGCAAGGACATGTTGAATGATTACGGTACAATACATTTCACATCGACGTCGAACGGTCGCGTCATGTCTTTCGACCGGAAGACCGGCGACCTCGTCTGGTCCCACAACTTTGGGACTCCGGTCGTAGCTGCCTACCTCCTGGACAGAGACGGCCTTATCTCCGTCCCTTTCAACTCGATCGGTGACGACACGCTCGATCATATCATGGAGGACGCTAAAACCCTTTCGAACGGGAAAGGACTCAAAAATTCGAATATCGAATTGTACCCGACTTTATACGTCGGTGAGCATAACCACGGTCTATACGCGCTATCGTCGTTAGTCGATAAAAACACGATAACTATATCGACGGGTCATCAGCCCTTGCTCATCGAAGGCCCCTCGACGGAGACACTAAAGACGAACGCGCCGCGCTACGAGCCTATCAAGAACATCCACTACAAACTGAGCGACCTTAACTTGCACGTCTCGGCGCCGTATCTCCTTCTCGGCCACTACAAAGTTCCGGAACTGACGACCTCCTGGATACCCCATTTGCCTAACTCGAACGTTTTGAACCTGAGAGATCCACAAATCGATTCAATAAAACTAATCAACGGAGCAGTACAAGCTCAGACGGAGAATGACGTTGAGAACGAAACGAATTTGAAGTCCAATTCGGTATCAGTTTCGGTTCAGACTGAGGATTTGTTCGAGGGTTTGTCGTTCAGGCCCGATCTGTGGTACAAGCAGGCCCACGTTTGGCTCCACCAGCAGGAGAATAAAGTGCTGAAAGTGGCACTAATTATTCTCGTCGGTTTGGTCATCGCCATGTTCTGGTACTTAAGGCTGCAGGCTCGTGAGTTCCAACAACTATCGCAAGGCGGTTCCCGAAGCTCCACCTCATCTACGTCGTCCCAGGGCGAAGTTACCGGTCAGCTCATGGAAATAGGAGAGGGTGAAATGAAGATCGGAAAGATTACATTCCAGACAGATCAGGTGCTGGGAAAAGGTTGCGAAGGCACCTTCGTTTACAGAGGGACTTTCGATAAACGCGACGTGGCAGTAAAACGATTGCTCCCTGAGTGTTTCACGTTCGCCGACCGCGAGGTGGCGCTGCTGCGGGAGTCGGACGCGCACGCACACGTCGTGCGCTACTACTGTACTGAACGCGATAAGCAGTTCAGGTACATTGCACTAGAGCTATGTTCAGCGACATTGCAGGACTATGTTGAGAAGAAGTTGAACTTCGAGTGCAAGATTGATTCGGTCGAAATACTGAGGCAGGCCACTATGGGCTTATCGCACTTACACTCTATGGATATAGTACATAGGGATGTGAAGCCGCACAACGTTTTGCTGTCGATGCCGAGTGGGACCGGCGAGGTGCGCGCCATGATATCGGACTTCGGCCTGTCCAAGAAGCTGAACATAGGGCGGGTCAGCTTCTCGAGGCGCTCTGGGGTCACCGGCACCGACGGCTGGATAGCGCCGGAGATGATCAACGGCGAACGGACTACGACATCGATCGATATATTTTCGTTGGGCTGCGTGTTCTATTACGTATTGTCAAGAGGACAACATCCATTCGGTGATGTTTTGCGGCGTCAAGCGAACATACTCACCGGGGACTACAATTTGGATCACCTCGACAAAATTCTGCCTGAAGAGGAATTGGTAGTGGTTAAAATATTGATCCGAGCTATGATCTCGGCCAAGCCCAGCGCACGTCCTCCCTGCGAAACGATACTGAAATACCCGATGTTCTGGTGCAAGCAAAGCATTCTGAACTTCTTGCAGGACGTCAGCGATCAAGTGGAGAGTTGTGCGTGCGGTTTTGGGGCGGAGCACACGCTGGAGCGGGGCGGCGCGCGGGTGCTGCGCGGCGACTGGCGCGCGCGCGTGTGCCGCGTGGTGGCGGGCGACCTGCGCACGCGCCGCACGTACCGCGGGGACCGCGTCGCGCACCTGCTGCGGGCCATCCGGAACAAGGTACCGACACCGACCAGACCACATAGTGGTCTTCTTCTTCCGGCTGTTTTGAAGAGTATATACTGGGTGTTAGGATACCGCTTCCGAAAATGA

Protein

MKFLLLILFLLGSSGFGTVVDEEGKESTEISRALDDRPLLFATLGGGMVAVDPVSGDIIWKLKDEPVVKVPSQDANLMPQFLPDPRHGFLYTYGPRGDQQMLKKLPFTIPELVANAPCRSTDGILYTGKKSDTWFMIDPLTGFREHVSGFDKSKIFKSDDENTCNSEKKKGIYVARTEYNILMHDSKNVNHKWNVTFFDYTSLAMGKDMLNDYGTIHFTSTSNGRVMSFDRKTGDLVWSHNFGTPVVAAYLLDRDGLISVPFNSIGDDTLDHIMEDAKTLSNGKGLKNSNIELYPTLYVGEHNHGLYALSSLVDKNTITISTGHQPLLIEGPSTETLKTNAPRYEPIKNIHYKLSDLNLHVSAPYLLLGHYKVPELTTSWIPHLPNSNVLNLRDPQIDSIKLINGAVQAQTENDVENETNLKSNSVSVSVQTEDLFEGLSFRPDLWYKQAHVWLHQQENKVLKVALIILVGLVIAMFWYLRLQAREFQQLSQGGSRSSTSSTSSQGEVTGQLMEIGEGEMKIGKITFQTDQVLGKGCEGTFVYRGTFDKRDVAVKRLLPECFTFADREVALLRESDAHAHVVRYYCTERDKQFRYIALELCSATLQDYVEKKLNFECKIDSVEILRQATMGLSHLHSMDIVHRDVKPHNVLLSMPSGTGEVRAMISDFGLSKKLNIGRVSFSRRSGVTGTDGWIAPEMINGERTTTSIDIFSLGCVFYYVLSRGQHPFGDVLRRQANILTGDYNLDHLDKILPEEELVVVKILIRAMISAKPSARPPCETILKYPMFWCKQSILNFLQDVSDQVESCACGFGAEHTLERGGARVLRGDWRARVCRVVAGDLRTRRTYRGDRVAHLLRAIRNKVPTPTRPHSGLLLPAVLKSIYWVLGYRFRK

Uniprot

H9ISF3   A0A2H1WVP0   A0A3S2NTW7   A0A212FI45   D6WVT7   A0A1Y1LCF4   + More
A0A0M9A867   A0A0L7RD49   A0A087ZS85   A0A154PPG3   K7IMS0   A0A232FJS9   A0A2J7QD78   A0A067QMX0   A0A0C9PRE8   A0A2A3E0C8   A0A310SFX9   A0A195CX64   F4WK76   A0A1W4X0U2   A0A1W4XBN9   A0A151JCV0   A0A336M6W9   A0A336M157   A0A151JWF8   A0A158NMN3   N6TY92   U4TV90   E2ABW3   A0A1W4W954   A0A034VU66   Q16QF5   A0A0L0CHF2   A0A0K8UNN4   A0A0A1WHF9   B0W329   B4M4R7   A0A1Q3FEU8   E9I8H9   U5ELH4   B3P081   B3LXS2   A0A1I8PWC0   A0A0M4EG85   A8JR46   A0A0R1E0R2   A0A1V0QBD0   A0A1Q3FBV8   B4JT13   A0A1A9VAE8   A0A3B0KDA0   A0A182GDU1   A0A3B0JNA6   A0A1B0BLV8   W8C6D6   B4K4S4   A0A1A9Y8J0   A0A1B0A230   A0A3B0KIY9   A0A195BWV4   A0A151WHG7   A0A1Q3FEV2   Q293L0   A0A1B0FQP8   B4NEZ0   E0VNS3   A0A1A9WJ68   A0A2M4BAU7   A0A2M4BAR9   A0A2M4BBW0   W5JVI7   A0A2M4A0A7   A0A182FSD4   A0A2M4A0B0   B4GLZ7   A0A2M4A091   A0A2M3YZA8   A0A182NLC8   A0A182JEQ0   A0A2M3ZE88   A0A182P6S0   A0A182QMN2   A0A182M786   A0A182XJ45   A0A1J1IPL6   A0A182UWC3   A0A182JTD1   A0A182L7A8   A0A2M3Z014   A0A340TBI4   A0A182I7R6   B4IHR9   Q5TTF0   A0A1B6MTN9   A0A182RYP4   A0A1B6C1J1   A0A1B6IQ08  

Pubmed

19121390    22118469    18362917    19820115    28004739    20075255    + More
28648823    24845553    21719571    21347285    23537049    20798317    25348373    17510324    26108605    25830018    17994087    21282665    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17550304    28356351    26483478    24495485    15632085    20566863    20920257    23761445    20966253    12364791    14747013    17210077   

EMBL

BABH01040313    BABH01040314    BABH01040315    BABH01040316    BABH01040317    ODYU01011405    + More
SOQ57130.1    RSAL01000200    RVE44453.1    AGBW02008437    OWR53397.1    KQ971358    EFA08613.1    GEZM01062149    GEZM01062148    GEZM01062147    JAV70010.1    KQ435714    KOX79225.1    KQ414615    KOC68783.1    KQ435010    KZC13752.1    NNAY01000124    OXU30749.1    NEVH01015826    PNF26541.1    KK853134    KDR10833.1    GBYB01003858    JAG73625.1    KZ288486    PBC25233.1    KQ760382    OAD60687.1    KQ977231    KYN04749.1    GL888194    EGI65399.1    KQ979038    KYN23486.1    UFQT01000645    SSX26054.1    UFQS01000410    UFQT01000410    SSX03691.1    SSX24056.1    KQ981653    KYN38619.1    ADTU01020633    ADTU01020634    ADTU01020635    ADTU01020636    ADTU01020637    APGK01057050    APGK01057051    KB741277    ENN71262.1    KB631617    ERL84717.1    GL438386    EFN69058.1    GAKP01012953    JAC45999.1    CH477750    EAT36621.1    JRES01000405    KNC31642.1    GDHF01024344    JAI27970.1    GBXI01016499    GBXI01007192    JAC97792.1    JAD07100.1    DS231830    EDS30737.1    CH940652    EDW59628.2    GFDL01008976    JAV26069.1    GL761553    EFZ23129.1    GANO01001406    JAB58465.1    CH954181    EDV48455.1    CH902617    EDV41729.1    CP012526    ALC47341.1    AE014297    ABW08704.1    CM000160    KRK02892.1    KX683314    ARE59261.1    GFDL01010067    JAV24978.1    CH916373    EDV94903.1    OUUW01000008    SPP83706.1    JXUM01056628    JXUM01056629    JXUM01056630    KQ561918    KXJ77167.1    SPP83707.1    JXJN01016586    JXJN01016587    GAMC01008601    JAB97954.1    CH933806    EDW16077.2    SPP83708.1    KQ976395    KYM93114.1    KQ983118    KYQ47270.1    GFDL01008972    JAV26073.1    CM000070    EAL29205.3    CCAG010014772    CH964251    EDW83365.2    DS235346    EEB15029.1    GGFJ01000991    MBW50132.1    GGFJ01000992    MBW50133.1    GGFJ01001372    MBW50513.1    ADMH02000361    ETN66834.1    GGFK01000916    MBW34237.1    GGFK01000902    MBW34223.1    CH479185    EDW38571.1    GGFK01000915    MBW34236.1    GGFM01000851    MBW21602.1    GGFM01006068    MBW26819.1    AXCN02000121    AXCM01003760    CVRI01000056    CRL01658.1    GGFM01001109    MBW21860.1    APCN01002549    CH480840    EDW49436.1    AAAB01008880    EAL40662.4    GEBQ01000680    JAT39297.1    GEDC01030193    GEDC01027232    JAS07105.1    JAS10066.1    GECU01018701    JAS89005.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000007266    UP000053105    UP000053825    + More
UP000005203    UP000076502    UP000002358    UP000215335    UP000235965    UP000027135    UP000242457    UP000078542    UP000007755    UP000192223    UP000078492    UP000078541    UP000005205    UP000019118    UP000030742    UP000000311    UP000192221    UP000008820    UP000037069    UP000002320    UP000008792    UP000008711    UP000007801    UP000095300    UP000092553    UP000000803    UP000002282    UP000001070    UP000078200    UP000268350    UP000069940    UP000249989    UP000092460    UP000009192    UP000092443    UP000092445    UP000078540    UP000075809    UP000001819    UP000092444    UP000007798    UP000009046    UP000091820    UP000000673    UP000069272    UP000008744    UP000075884    UP000075880    UP000075885    UP000075886    UP000075883    UP000076407    UP000183832    UP000075903    UP000075881    UP000075882    UP000075920    UP000075840    UP000001292    UP000007062    UP000075900   

PRIDE

H9ISF3    A8JR46   

Pfam

PF00069   Pkinase        + More
PF06479   Ribonuc_2-5A
PF00850   Hist_deacetyl
PF02148   zf-UBP
PF01011   PQQ
PF00215   OMPdecase
PF00156   Pribosyltran

Interpro

IPR000719   Prot_kinase_dom        + More
IPR038357   KEN_sf       
IPR018391   PQQ_beta_propeller_repeat       
IPR011009   Kinase-like_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR011047   Quinoprotein_ADH-like_supfam       
IPR018997   PUB_domain       
IPR010513   KEN_dom       
IPR008271   Ser/Thr_kinase_AS       
IPR033523   IRE2       
IPR023801   His_deacetylse_dom       
IPR001607   Znf_UBP       
IPR000286   His_deacetylse       
IPR023696   Ureohydrolase_dom_sf       
IPR037138   His_deacetylse_dom_sf       
IPR013083   Znf_RING/FYVE/PHD       
IPR002372   PQQ_repeat       
IPR011044   Quino_amine_DH_bsu       
IPR001754   OMPdeCOase_dom       
IPR029057   PRTase-like       
IPR000836   PRibTrfase_dom       
IPR018089   OMPdecase_AS       
IPR023031   OPRT       
IPR014732   OMPdecase       
IPR011060   RibuloseP-bd_barrel       
IPR013785   Aldolase_TIM       
IPR004467   Or_phspho_trans_dom       

SUPFAM

SSF56112   SSF56112        + More
SSF50998   SSF50998       
SSF52768   SSF52768       
SSF50969   SSF50969       
SSF53271   SSF53271       
SSF51366   SSF51366       

Gene 3D

1.20.1440.180     2.130.10.10     3.30.40.10     3.40.800.20     3.20.20.70    

CDD

cd06223  PRTases_typeI

ProteinModelPortal

H9ISF3   A0A2H1WVP0   A0A3S2NTW7   A0A212FI45   D6WVT7   A0A1Y1LCF4   + More
A0A0M9A867   A0A0L7RD49   A0A087ZS85   A0A154PPG3   K7IMS0   A0A232FJS9   A0A2J7QD78   A0A067QMX0   A0A0C9PRE8   A0A2A3E0C8   A0A310SFX9   A0A195CX64   F4WK76   A0A1W4X0U2   A0A1W4XBN9   A0A151JCV0   A0A336M6W9   A0A336M157   A0A151JWF8   A0A158NMN3   N6TY92   U4TV90   E2ABW3   A0A1W4W954   A0A034VU66   Q16QF5   A0A0L0CHF2   A0A0K8UNN4   A0A0A1WHF9   B0W329   B4M4R7   A0A1Q3FEU8   E9I8H9   U5ELH4   B3P081   B3LXS2   A0A1I8PWC0   A0A0M4EG85   A8JR46   A0A0R1E0R2   A0A1V0QBD0   A0A1Q3FBV8   B4JT13   A0A1A9VAE8   A0A3B0KDA0   A0A182GDU1   A0A3B0JNA6   A0A1B0BLV8   W8C6D6   B4K4S4   A0A1A9Y8J0   A0A1B0A230   A0A3B0KIY9   A0A195BWV4   A0A151WHG7   A0A1Q3FEV2   Q293L0   A0A1B0FQP8   B4NEZ0   E0VNS3   A0A1A9WJ68   A0A2M4BAU7   A0A2M4BAR9   A0A2M4BBW0   W5JVI7   A0A2M4A0A7   A0A182FSD4   A0A2M4A0B0   B4GLZ7   A0A2M4A091   A0A2M3YZA8   A0A182NLC8   A0A182JEQ0   A0A2M3ZE88   A0A182P6S0   A0A182QMN2   A0A182M786   A0A182XJ45   A0A1J1IPL6   A0A182UWC3   A0A182JTD1   A0A182L7A8   A0A2M3Z014   A0A340TBI4   A0A182I7R6   B4IHR9   Q5TTF0   A0A1B6MTN9   A0A182RYP4   A0A1B6C1J1   A0A1B6IQ08  

PDB

6HV0     E-value=1.62412e-112,     Score=1042

KEGG

101746571    K08852 serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-] | (RefSeq) serin

PATHWAY

04140    Autophagy - animal - Bombyx mori (domestic silkworm)
04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)

GO

GO:0004540   GO:0006397   GO:0016021   GO:0004672   GO:0005524   GO:0005789   GO:0030968   GO:0070059   GO:1990604   GO:0004521   GO:0036498   GO:0004674   GO:0051082   GO:0008270   GO:0006402   GO:0043484   GO:0007030   GO:0061541   GO:0006468   GO:0001751   GO:0034976   GO:0009116   GO:0004590   GO:0044205   GO:0004588   GO:0006207   GO:0004812   GO:0006418   GO:0003723   GO:0046872   GO:0003824   GO:0005515  

PANTHER

PTHR13954:SF15  

SignalP

Position:   1 - 17,         Likelihood:  0.996013

 

 

Length:

892

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

14.07498

Exp number, first 60 AAs:

0.57131

Total prob of N-in:

0.05248

outside

1  -  892

 

 

Pi

178.357639

Theta

155.440467

Tajima's D

-1.95567

CLR

0.753879

CSRT

0.0168491575421229

Interpretation

Possibly Positive selection