Gene

KWMTBOMO10188

Pre Gene Modal

BGIBMGA005614

Annotation

PREDICTED:_TBC1_domain_family_member_16_[Amyelois_transitella]

Location

Bomo_Chr17(-):4141607-4149682      View in EpiBrowser

Full name

Dipeptidase      

Location in the cell

Nuclear   Reliability : 3.349

CDS

ATGCCCCTTCCTGATCTACTTAGGCGAGCTTCGAGCTATTTTCTCGGCATCGACTTCGACGACGAGGACCCACCTGATTACGTCGACAACGAAATACTATTCTGTAAGAATAACGTTTGCGTCCATCCTCCAACGATCGCGAGGCACGAATTAGATATCATACATCACCCCGGCTACTTGACTATCACGACTAAAGTGTTTACCGATCAGCACAATAACGCTAAACGTCCGACTTTGTTTTTGAATTGGATTCCGAACTCTACCCTTCGAAAATGTCCGTCTGCGGTTGAAACCAGTCCTAGCGATGAGCTCGGCTGTGTTGTCAACAAACCGACCGCTCCGAGGCAAATACCTTACACACAATCGCACAACGATTCGAACATATCGATAAAGAATGACATTGAAAATGCATTCTCTGATTCGTCGGAGACGACAAGCCTCAATTCTAATTCTGATAAACAGAGCCTAAAGTCTACCGACACTAGGTACACGCCGAACGATACGACGCAAGACGAGCTATCTTCCAGCTCTAAGCCAACAGTAAAATCAATTGATTCAGGAAAAGACAACGTGTTCAGCAGCTTCGAGAAGGAAGAATTGAAGAACGACGTGTTTATATATGATAAACACGTGAGATCTCAGTCTATGACCTCTGTGAACATTACAATCGCTAATCCGACTATAGAAAACGTTGATCTGACCCCTGATTCGCTGTCGAGCGACAGGTATATTAGGTCGCTATCGCTTAGCTCGTGTGACGAAGGTAATCCTAATTGGATGAGCACCCCCGAGTTCTTGGCGCTGAAACACAATTTGGTGTTTCCCGACAGCGTTCATAGCTCGCCGGTCCCACAGAGGCGAGCTCCGTTGAAATGTCGAAGATTTTCAGTAGATCTCTCCCAGATGCGTTCTCTGCGATTGTTTTTCAATGACGACAACTGCACGTGTGGGCAGTTGGTAGTGGCATCCCGAGAGTCTCAGTACAAGATTTTGCATTTCCATCACGGAGGCTTGGATCATCTGGCGCAGGTTCTACACCGATGGCATTCGCTGTTACACAATATAAAACTTACGCCAGGGTCCGAGGAACCGAATATGCCGTACCGACATTTCATGGTGTGCCGTCCGGAAGTGCAAAAGTCAGAGCAGCATCCGGAGGAAGGGAAATTGCCAAAGATAACACCAGAACTGTTCTACGGGAAACTCATGAACGGCAAAGGGGTTATCGAAGACGATCTTTTCTTAAGGAAATGCATCTTCTTCGGAGGTTTAGATAAAGAGCTGAGACGCGAAGTCTGGCCTTTCCTGTTACACTGCTATCCGTATAACTCGACGTATGAAGAGAGGGAAATTATCTTACAAATAAGAACGAAAGATTACGAAGAAATAACGAGGCGTAGACTTGAAAGGATGACTCCGGATCAGCACGTCATGTTTAGGAAAACAATACAATGCGTCGTCGAGAAGGATGTAGTGCGGACTGACAGAGGAAATCCTTTCTTCGCCGGCGAAAATAATTACAACGTTGAGATAATGAAGAATATATTACTGAACTATGCCGTATATAATCCAGTATTAGGTTACACGCAAGGTATGAGTGACCTATTGGCGCCGGTTCTGTGTGAAATAAAGTGCGAAGCGGAGGCTTTCTGGTGTTTCGTTGGTCTCATGCAGCGAGCTATATTCGTTTGTACGCCCACGGATAATGACATGGACAATAACCTTAGTTTTCTCCGTGAATTGATCAGAATAATGTTACCTCACTTCTACAAGCATTTGGAGAAACACGTTGACGCAATGGAATTACTATTTTGTCACCGGTGGATACTTTTATGTTTCAAACGCGAATTCACCGAGGCCGTAGCCCTTCGTATGTGGGAGGCTTGCTGGGCCAACTATCAGACGGATTACTTTCATCTGTTCCTGTGCTTGGCTATTGTAGCCGTTTACGCTGATGACGTCATAGCACAAGATCTCAATACCGACGAAATGCTGTTGCATTTTAGTTCTTTAGCCATGTACATGGATGGGCGTTTGATACTTCGCAAAGCTCGTGGTCTGCTTTACCAGTTCAGGCAGTTAGTAAGGATCCCTTGTACCCTCGCTGGAATGTGCCAACGATGTGGCCCTGGCATTTGGGATTCCACACATCGGCCTAGCGTAGAGTGCACTGGGGCTCACGATATATGCAAATTTGATGTACAGTGA

Protein

MPLPDLLRRASSYFLGIDFDDEDPPDYVDNEILFCKNNVCVHPPTIARHELDIIHHPGYLTITTKVFTDQHNNAKRPTLFLNWIPNSTLRKCPSAVETSPSDELGCVVNKPTAPRQIPYTQSHNDSNISIKNDIENAFSDSSETTSLNSNSDKQSLKSTDTRYTPNDTTQDELSSSSKPTVKSIDSGKDNVFSSFEKEELKNDVFIYDKHVRSQSMTSVNITIANPTIENVDLTPDSLSSDRYIRSLSLSSCDEGNPNWMSTPEFLALKHNLVFPDSVHSSPVPQRRAPLKCRRFSVDLSQMRSLRLFFNDDNCTCGQLVVASRESQYKILHFHHGGLDHLAQVLHRWHSLLHNIKLTPGSEEPNMPYRHFMVCRPEVQKSEQHPEEGKLPKITPELFYGKLMNGKGVIEDDLFLRKCIFFGGLDKELRREVWPFLLHCYPYNSTYEEREIILQIRTKDYEEITRRRLERMTPDQHVMFRKTIQCVVEKDVVRTDRGNPFFAGENNYNVEIMKNILLNYAVYNPVLGYTQGMSDLLAPVLCEIKCEAEAFWCFVGLMQRAIFVCTPTDNDMDNNLSFLRELIRIMLPHFYKHLEKHVDAMELLFCHRWILLCFKREFTEAVALRMWEACWANYQTDYFHLFLCLAIVAVYADDVIAQDLNTDEMLLHFSSLAMYMDGRLILRKARGLLYQFRQLVRIPCTLAGMCQRCGPGIWDSTHRPSVECTGAHDICKFDVQ

Catalytic Activity

Hydrolysis of dipeptides.

Cofactor

Zn(2+)

Subunit

Homodimer; disulfide-linked.

Similarity

Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.

Uniprot

H9J7X2   A0A2A4JHR5   A0A2A4JGR7   A0A194QSG0   A0A194QAW1   A0A3S2ND72   + More
A0A1E1WA97   A0A2H1WQ64   A0A1S4F2T5   A0A182MFU8   Q17HC8   A0A182RCY0   A0A182PI76   A0A182VLZ9   A0A182X8G2   A0A182HFZ6   Q7PSN4   A0A182JRS8   A0A084W3K6   A0A336LEL2   A0A336N7G9   A0A1J1IU37   A0A0L0C5C2   A0A1B0F9A1   A0A1A9VVC2   A0A1A9W0P2   A0A1A9XCN7   A0A1B0BLL5   A0A1B0AA35   A0A1W4XIS1   B4MUC0   B4LVD0   A0A1I8M388   A0A0M3QTQ0   D6WYD1   B4JPZ1   A0A3B0K1D9   A0A1I8PXJ7   B4KHS3   B4G787   N6TFC9   B4HWP8   Q8SY79   B4NZP9   Q9VKV6   B3N9Q4   A0A0J9R074   B4Q9A5   B3MJI2   A0A1W4UT53   A0A182WDC9   A0A1Y1LYX6   A0A1Y1LWL9   A0A182QD00   A0A182SXG9   A0A182MXH4   W5JE18   A0A182FVJ7   A0A182JIF2   E2AFQ7   A0A034VR64   A0A310S4B3   A0A0L7QNR7   A0A087ZZI8   A0A2A3ENU2   A0A151K194   K7J5G4   E2BJ03   A0A0K8WFT1   A0A232FKU0   A0A067RU03   A0A0C9RCD1   W8BRX1   A0A026WK95   A0A0N0BI89   A0A151JNL8   A0A1B6JDU5   A0A2P8Z2K7   A0A1B6D4D2   A0A0J7KZ84   V4B0P5   R7V0N7   A0A3S3NSW4   A0A3S3RVU3  

EC Number

3.4.13.19

Pubmed

19121390    26354079    17510324    12364791    24438588    26108605    + More
17994087    25315136    18362917    19820115    18057021    23537049    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    28004739    20920257    23761445    20798317    25348373    20075255    28648823    24845553    24495485    24508170    30249741    29403074    23254933   

EMBL

BABH01020120    NWSH01001429    PCG71258.1    PCG71257.1    KQ461155    KPJ08254.1    + More
KQ459232    KPJ02678.1    RSAL01000090    RVE48059.1    GDQN01007151    JAT83903.1    ODYU01010223    SOQ55193.1    AXCM01007452    CH477250    EAT46078.1    APCN01005441    AAAB01008816    EAA05292.5    ATLV01020056    KE525293    KFB44800.1    UFQS01003103    UFQT01003103    SSX15207.1    SSX34582.1    UFQT01003112    SSX34598.1    CVRI01000059    CRL03218.1    JRES01000893    KNC27480.1    CCAG010013973    JXJN01016437    JXJN01016438    CH963857    EDW76046.1    CH940649    EDW63309.1    CP012523    ALC39269.1    KQ971356    EFA09112.1    CH916372    EDV98971.1    OUUW01000006    SPP81680.1    CH933807    EDW13360.1    KRG03714.1    CH479180    EDW28341.1    APGK01039925    APGK01039926    APGK01039927    KB740975    ENN76473.1    CH480818    EDW52443.1    AY071730    AAL49352.1    CM000157    EDW88833.1    AE014134    BT046168    AAF52952.2    ACI47090.1    CH954177    EDV58549.1    CM002910    KMY89546.1    CM000361    EDX04547.1    CH902620    EDV32350.1    GEZM01045083    JAV77928.1    GEZM01045082    JAV77929.1    AXCN02001709    ADMH02001496    ETN62311.1    GL439124    EFN67736.1    GAKP01014899    GAKP01014893    JAC44053.1    KQ779356    OAD51992.1    KQ414855    KOC60131.1    KZ288212    PBC32799.1    KQ981189    KYN45237.1    GL448543    EFN84348.1    GDHF01002372    GDHF01001671    JAI49942.1    JAI50643.1    NNAY01000065    OXU31366.1    KK852421    KDR24295.1    GBYB01014229    JAG83996.1    GAMC01002450    JAC04106.1    KK107167    QOIP01000010    EZA56472.1    RLU18000.1    KQ435732    KOX77342.1    KQ978820    KYN28146.1    GECU01010573    JAS97133.1    PYGN01000224    PSN50723.1    GEDC01016746    JAS20552.1    LBMM01001888    KMQ95603.1    KB199905    ESP03758.1    AMQN01006457    KB298404    ELU09246.1    NCKU01004802    RWS05417.1    NCKU01004750    RWS05489.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000075883    + More
UP000008820    UP000075900    UP000075885    UP000075903    UP000076407    UP000075840    UP000007062    UP000075881    UP000030765    UP000183832    UP000037069    UP000092444    UP000078200    UP000091820    UP000092443    UP000092460    UP000092445    UP000192223    UP000007798    UP000008792    UP000095301    UP000092553    UP000007266    UP000001070    UP000268350    UP000095300    UP000009192    UP000008744    UP000019118    UP000001292    UP000002282    UP000000803    UP000008711    UP000000304    UP000007801    UP000192221    UP000075920    UP000075886    UP000075901    UP000075884    UP000000673    UP000069272    UP000075880    UP000000311    UP000053825    UP000005203    UP000242457    UP000078541    UP000002358    UP000008237    UP000215335    UP000027135    UP000053097    UP000279307    UP000053105    UP000078492    UP000245037    UP000036403    UP000030746    UP000014760    UP000285301   

PRIDE

H9J7X2    Q8SY79    Q9VKV6   

Pfam

PF00566   RabGAP-TBC        + More
PF01244   Peptidase_M19
PF03022   MRJP

Interpro

IPR000195   Rab-GTPase-TBC_dom        + More
IPR035969   Rab-GTPase_TBC_sf       
IPR008257   Pept_M19       
IPR032466   Metal_Hydrolase       
IPR017996   Royal_jelly/protein_yellow       
IPR011042   6-blade_b-propeller_TolB-like       

SUPFAM

SSF47923   SSF47923        + More
SSF51556   SSF51556       

Gene 3D

2.120.10.30    

ProteinModelPortal

H9J7X2   A0A2A4JHR5   A0A2A4JGR7   A0A194QSG0   A0A194QAW1   A0A3S2ND72   + More
A0A1E1WA97   A0A2H1WQ64   A0A1S4F2T5   A0A182MFU8   Q17HC8   A0A182RCY0   A0A182PI76   A0A182VLZ9   A0A182X8G2   A0A182HFZ6   Q7PSN4   A0A182JRS8   A0A084W3K6   A0A336LEL2   A0A336N7G9   A0A1J1IU37   A0A0L0C5C2   A0A1B0F9A1   A0A1A9VVC2   A0A1A9W0P2   A0A1A9XCN7   A0A1B0BLL5   A0A1B0AA35   A0A1W4XIS1   B4MUC0   B4LVD0   A0A1I8M388   A0A0M3QTQ0   D6WYD1   B4JPZ1   A0A3B0K1D9   A0A1I8PXJ7   B4KHS3   B4G787   N6TFC9   B4HWP8   Q8SY79   B4NZP9   Q9VKV6   B3N9Q4   A0A0J9R074   B4Q9A5   B3MJI2   A0A1W4UT53   A0A182WDC9   A0A1Y1LYX6   A0A1Y1LWL9   A0A182QD00   A0A182SXG9   A0A182MXH4   W5JE18   A0A182FVJ7   A0A182JIF2   E2AFQ7   A0A034VR64   A0A310S4B3   A0A0L7QNR7   A0A087ZZI8   A0A2A3ENU2   A0A151K194   K7J5G4   E2BJ03   A0A0K8WFT1   A0A232FKU0   A0A067RU03   A0A0C9RCD1   W8BRX1   A0A026WK95   A0A0N0BI89   A0A151JNL8   A0A1B6JDU5   A0A2P8Z2K7   A0A1B6D4D2   A0A0J7KZ84   V4B0P5   R7V0N7   A0A3S3NSW4   A0A3S3RVU3  

PDB

5TUC     E-value=2.00726e-42,     Score=437

KEGG

101740217    no KO assigned | (RefSeq) TBC1 domain family member 16

GO

GO:0017137   GO:0006886   GO:0005769   GO:0005096   GO:0090630   GO:0008237   GO:0046872   GO:0016021   GO:0016805   GO:0031225   GO:0043087  

PANTHER

PTHR10443   PTHR10009  

Subcellular location

Membrane  

Length:

735

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.13694

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00011

outside

1  -  735

 

 

Pi

216.514435

Theta

164.309027

Tajima's D

-1.743531

CLR

0.150027

CSRT

0.0347482625868707

Interpretation

Uncertain