Silkworm Genome Informatics Database

Gene

KWMTBOMO10121

Annotation

PREDICTED:_protein_cortex-like?_partial_[Amyelois_transitella]

Location

Bomo_Chr17(-):2501816-2506994 View in EpiBrowser

Full name

Protein cortex

Location in the cell

Mitochondrial Reliability : 1.727 Nuclear Reliability : 2.189

CDS

ATGAATAGAACTGCGTTTGGAAAGAAGAGTTTGAATAGGCGGCGACCCCGAGTGGATAGGTTCGTTCTACCCAGGGAACAACTGGCCGAGATTAAAAGTCGCGCTCTTTGGAAAATACCCTCAGCTTACACTGGCGACATTTGGAGTTCAGAATACTTACAACGGAAGAAATATGCTGAATATTTAGATGAAGCTTTCGGTTTGGAACCCTTGAAAGCTCATGATTGTAACCAGTCGATACCTGACGGGTACAGAGCTCAAGCCTGGCCCTGCGTGCCCAGAAAACGTAGATACCTCACTTCAGCCGACAGCATATTGGATCTACCGACATACAGCTATGCTTTGTGTACATTTTACATTATTTTAATCTCTCATATGAGGCAGTAG

Protein

MNRTAFGKKSLNRRRPRVDRFVLPREQLAEIKSRALWKIPSAYTGDIWSSEYLQRKKYAEYLDEAFGLEPLKAHDCNQSIPDGYRAQAWPCVPRKRRYLTSADSILDLPTYSYALCTFYIILISHMRQ

Description

Controls wing pigmentation patterning, possibly by regulating scale cell development (PubMed:27251284). Probably acts as an activator of the anaphase promoting complex/cyclosome (APC/C) that promotes the ubiquitin ligase activity and substrate specificity of the APC/C (By similarity).
Controls wing pigmentation patterning by regulating scale cell development, thereby playing a key role in mimicry and crypsis (PubMed:27251285). Probably acts as an activator of the anaphase promoting complex/cyclosome (APC/C) that promotes the ubiquitin ligase activity and substrate specificity of the APC/C (By similarity).

Similarity

Belongs to the WD repeat CORT family.

Keywords

Alternative splicing Cytoplasm Repeat WD repeat

Feature

chain Protein cortex
splice variant In isoform B4.

Uniprot

A0A173FD09 P0DOC0 A0A3S2L785 A0A212EI88 P0DOB8 A0A194QGP3 + More
L7X1N7 P0DOB9 A0A194QXL3

Pubmed

27251284 22118469 27251285 26354079 23674305

EMBL

KT182637 ANG83460.1 KT235895 KT235896 KT235897 KT235898 + More
KT235899 KT235900 KT235901 KT235902 KT235903 KT235904 KT235905 KT235906 RSAL01000108 RVE47260.1 AGBW02014684 OWR41180.1 KQ459232 KPJ02616.1 KC469893 AGC92688.2 KQ461155 KPJ08316.1

Proteomes

UP000283053 UP000007151 UP000053268 UP000053240

PRIDE

P0DOB8

Pfam

PF00400 WD40

Interpro

IPR015943   WD40/YVTN_repeat-like_dom_sf        + More
IPR001680   WD40_repeat
IPR033010   Cdc20/Fizzy
IPR017986   WD40_repeat_dom
IPR036322   WD40_repeat_dom_sf
IPR019775   WD40_repeat_CS

SUPFAM

SSF50978 SSF50978

Gene 3D

2.130.10.10

ProteinModelPortal

A0A173FD09 P0DOC0 A0A3S2L785 A0A212EI88 P0DOB8 A0A194QGP3 + More
L7X1N7 P0DOB9 A0A194QXL3

KEGG

101744919 K03363 cell division cycle 20, cofactor of APC complex | (RefSeq) protein cortex

PATHWAY

04120 Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)

GO

GO:1904668 GO:0010997 GO:0097027 GO:0005737 GO:0051301

PANTHER

PTHR19918

Subcellular location

Cytoplasm

Length:

128

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

19.02699

Exp number, first 60 AAs:

0.00094

Total prob of N-in:

0.84814

inside

1 - 103

TMhelix

104 - 126

outside

127 - 128

Pi

179.975549

Theta

168.63031

Tajima's D

0.115487

CLR

0.192312

CSRT

0.4036798160092

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics