Gene

KWMTBOMO10091

Pre Gene Modal

BGIBMGA005666

Annotation

PREDICTED:_ATP-dependent_DNA_helicase_Q1-like_[Amyelois_transitella]

Location

Bomo_Chr17(-):2165339-2167423      View in EpiBrowser

Full name

ATP-dependent DNA helicase       + More
ATP-dependent DNA helicase Q1      
Glycogen [starch] synthase      

Alternative Name

DNA-dependent ATPase Q1
RecQ protein-like 1

Location in the cell

Nuclear   Reliability : 2.448

CDS

ATGAAGACCATAGAAGAACTACAAAATGAACTTATCAGCGTTAACGACGAATTGCAAAAGGTCGATGCTGAACTTGAGAAATGGAGGACCCGGCAAAGAAAATTGCACGAAAAACGCAATAGTTTAAAAAATACTATTAATACTATAAAATCTGAAACATTAGCGAGCGTTGACTGGGCTGGTACTGAATACGAGTGGTCGGAAGACGTCAAAAATGTTTTAAAAGAAAAATTTCGATTAAAAACTTTTCGTGCGAAACAAATGAGCGCGATTAATTCCACGTTATCAGGCCAACACGCGATAGTCGTGATGCCGACAGGCGCCGGTAAGAGTCTTTGCTACCAGCTACCTGCACTCGTTAGGCCTGGACTAACAGTGGTCGTGTCACCACTCGTGTCGCTTATGGAAGACCAAGTAAGATCTCTCACAGATAAGAAAATAAGCGCCAAATTGATAACCAGCACTAGTCCAAAAGAGGAAACGTCTGCTGTACTGAACATGCTAAAAGACAAATCTGCCACTGTAAAACTATTATATGTAACTCCGGAACGTTTTGCTAAAAGTAAGAGATTCATGTCGAATTTGCAAAAATGTTATACTGATGGAAGCCTGCAAAGAATTGCTATTGATGAGGTTCACTGTTGTTCCCAGTGGGGTCATGACTTTAGACCTGATTATAAGTATCTTGGGATACTGACTCAAATATTTCCCAACATTCCAATATTGGGGTTAACTGCGACAGCTACTGCTCATGTTCTAAATGATGTTCAAAAAATACTAAACATACCTGGTTGCTTAATCATAAAATCTACATTTAATCGTCCTAATTTGTATTACAAAATTCTAGAGAAACCAACATCCCAAGATGATTGTCTCATTATATTAGAAAAACTTTTGAAATACAGGTACAAAGATCAATCTGGAATAATCTACACAAATAGCATAAAAGATGCTGAGGAAATAGCTGAAGGACTAAGGAAAAAAGGTCTAAAAGTGGCTTGTTATCATGCTAATTTAGATGCAGATATTAGATCAAAGGTCCATATCCGATGGCATGAACAACATTACCAAGCCATAGTTGCAACTGTAGCATTTGGCATGGGAATTGATAAACCAGATGTCAGGTTTGTCATACACCACACTATCAGCAAATCAATGGAAAACTACTACCAAGAGAGTGGAAGAGCTGGACGAGATGGTCTCAGAGCTGAGTGCATAACCCTGTACAGAATGCAGGACATATTTAAAGTGAGCACTATGGTATTTCAGTCTTCAGCTGGTAGCACTGATCATTTATATGAAATGGTGAAATATTGTCTTAATGGAACATTATGTCGGAGGCAAATTATTGCAAAACATTTTGATGAAGATTGGGGTGATAGTGACTGCAATAAGATGTGTGACGTTTGCAGTACCAGTCAATCAGATTCACCCAAAGATTTGGATCTTAGAGCTCATTGTAGGATTATTGCTCATATTCTAGAAAATGCTGAGAAGCTAGACACCAAATTAACAGCTCAGAAATTACTTGATGCATGGTTTTTAAAAGGGCCAGTAAATTTAAGACATAAAGGAAAGGAGCCAAATTTTCCTCGTGTTTTAGGTGAAGATGTTATAGCATTTTTATTAATAAACGGTTATTTAGTAGAAGATTTTCATTTCACTGCTTATTCGACTATAAGCTACCTAAAAATAGGTCCTGAAATGTCAGGAGTAAATAATGATGGCTTTAAGCTTAAAATGCGAGTTAGAGTTTATTCCCATTTTGAATTGAGCAAGCTGGCACCTACTGAATTGTTTGAAGAAACAGATAATAAATCAGTGAAAAGGAAAACAGAACCACCACCGCAAGTAAAGGTTAAGAGAAGATTGGTTGAAATTGATGATTAA

Protein

MKTIEELQNELISVNDELQKVDAELEKWRTRQRKLHEKRNSLKNTINTIKSETLASVDWAGTEYEWSEDVKNVLKEKFRLKTFRAKQMSAINSTLSGQHAIVVMPTGAGKSLCYQLPALVRPGLTVVVSPLVSLMEDQVRSLTDKKISAKLITSTSPKEETSAVLNMLKDKSATVKLLYVTPERFAKSKRFMSNLQKCYTDGSLQRIAIDEVHCCSQWGHDFRPDYKYLGILTQIFPNIPILGLTATATAHVLNDVQKILNIPGCLIIKSTFNRPNLYYKILEKPTSQDDCLIILEKLLKYRYKDQSGIIYTNSIKDAEEIAEGLRKKGLKVACYHANLDADIRSKVHIRWHEQHYQAIVATVAFGMGIDKPDVRFVIHHTISKSMENYYQESGRAGRDGLRAECITLYRMQDIFKVSTMVFQSSAGSTDHLYEMVKYCLNGTLCRRQIIAKHFDEDWGDSDCNKMCDVCSTSQSDSPKDLDLRAHCRIIAHILENAEKLDTKLTAQKLLDAWFLKGPVNLRHKGKEPNFPRVLGEDVIAFLLINGYLVEDFHFTAYSTISYLKIGPEMSGVNNDGFKLKMRVRVYSHFELSKLAPTELFEETDNKSVKRKTEPPPQVKVKRRLVEIDD

Description

DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity).
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate
[(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + H(+) + UDP

Subunit

Interacts with EXO1 and MLH1.

Similarity

Belongs to the helicase family. RecQ subfamily.
Belongs to the glycosyltransferase 3 family.

Keywords

Acetylation   ATP-binding   Complete proteome   DNA-binding   Helicase   Hydrolase   Nucleotide-binding   Nucleus   Phosphoprotein   Reference proteome  

Feature

chain  ATP-dependent DNA helicase

Uniprot

H9J824   A0A212FIK8   A0A2A4JJE6   A0A0L7LGS0   A0A194QSN4   A0A2H1WI67   + More
L7X1M6   C9S278   A0A194QAP1   E3UKN2   A0A2J7Q8Y3   A0A1B6JNR2   A0A1B6CUY3   A0A2P8YQL9   A0A1B6M5M1   A0A3L8DC02   A0A026WLE0   A0A067RX24   E0VZQ3   A0A2A3EM88   A0A087ZZI7   F4WEW0   A0A151X9X4   E9JCN0   A0A151JNL4   A0A151K1E3   W5JVH8   A0A310SCJ2   A0A154PK42   A0A0J7KYL3   A0A232FL31   A0A0L7QNC7   A0A336MJW4   A0A336L3W0   K7J5G3   A0A195B5U2   A0A158NWX1   A0A0P5DHV1   A0A182FUS3   E9G2Y5   A0A0P4VRU5   A0A0P5HZH7   A0A1Q3F0B8   A0A2J7Q8Y0   A0A0P5C8B0   B0XD44   A0A291S6Y1   A0A0P5B466   A0A087SWY7   A0A1B0CJD7   A0A1J1J5C0   A0A0C9RZJ3   A0JN36   J3S495   A0A2R5LAI8   A0A0P5ZDE8   K7F4Y8   H0VZ66   A0A0P5Z9P4   K7F4Y6   A0A1B0DNX2   Q6AYJ1   G1NLK6   A0A2Y9NEU0   A0A250YKF7   A0A341ADV5   A0A2U4BG13   T1E5X8   G1P5G3   M3XM99   A0A091ELU9   A0A2Y9FPS5   M3WQ95   A0A0B8RW48   A0A287BGJ9   A0A384B6I2   Q8AYS4   F1PNP1   A0A3Q7T7K4   A0A091X1R1   L5KKB3   A0A084VID9   A0A340WP44   A0A3Q7WV68   A0A384C948   A0A2D4PLK1   W5QGJ8   A0A091RGT0   A0A226N6V9   A0A182PC96   A0A1S3FXI9   L8INL4   A0A210PLF8   R0KZK1   A0A2S2QP09   G5BEF7   G1MCS7   F1SR01   S7N182   A0A0A0A487  

EC Number

3.6.4.12
2.4.1.11

Pubmed

19121390    22118469    26227816    26354079    23674305    29403074    + More
30249741    24508170    24845553    20566863    21719571    21282665    20920257    23761445    28648823    20075255    21347285    21292972    28992199    19393038    23025625    17381049    21993624    15489334    22673903    20838655    28087693    23758969    17975172    25727380    12724411    16341006    23258410    24438588    24813606    20809919    22751099    28812685    21993625    20010809   

EMBL

BABH01020287    AGBW02008375    OWR53551.1    NWSH01001193    PCG72187.1    JTDY01001185    + More
KOB74615.1    KQ461155    KPJ08329.1    ODYU01008735    SOQ52592.1    KC469893    AGC92678.1    CU367882    CBH09254.1    KQ459232    KPJ02603.1    HM449906    ADO33041.1    NEVH01016945    PNF25033.1    GECU01006887    JAT00820.1    GEDC01020006    JAS17292.1    PYGN01000430    PSN46523.1    GEBQ01008741    JAT31236.1    QOIP01000010    RLU17995.1    KK107167    EZA56471.1    KK852411    KDR24449.1    DS235854    EEB18859.1    KZ288212    PBC32800.1    GL888111    EGI67277.1    KQ982365    KYQ57144.1    GL771849    EFZ09441.1    KQ978820    KYN28147.1    KQ981189    KYN45238.1    ADMH02000317    ETN67005.1    KQ779356    OAD51993.1    KQ434924    KZC11590.1    LBMM01001888    KMQ95602.1    NNAY01000065    OXU31365.1    KQ414855    KOC60130.1    UFQT01001468    SSX30704.1    UFQS01000967    UFQT01000967    SSX08025.1    SSX28228.1    KQ976595    KYM79640.1    ADTU01028728    GDIP01157272    JAJ66130.1    GL732530    EFX86121.1    GDRN01102836    JAI58169.1    GDIQ01220890    JAK30835.1    GFDL01014045    JAV21000.1    PNF25032.1    GDIP01174467    JAJ48935.1    DS232740    EDS45279.1    MF433010    ATL75361.1    GDIP01189927    JAJ33475.1    KK112335    KFM57376.1    AJWK01014499    CVRI01000070    CRL07154.1    GBYB01002997    GBYB01014855    JAG72764.1    JAG84622.1    BC126495    AAI26496.1    JU174376    AFJ49902.1    GGLE01002387    MBY06513.1    GDIP01046288    JAM57427.1    AGCU01073460    AAKN02031107    GDIP01047888    JAM55827.1    AJVK01007806    AJVK01007807    BC079026    GFFW01000665    JAV44123.1    GAAZ01000710    JAA97233.1    AAPE02021857    AEYP01077487    AEYP01077488    AEYP01077489    KN121399    KFO36571.1    AANG04001751    GBKC01001018    JAG45052.1    AEMK02000034    AB074261    BAC20377.1    AAEX03015200    KK734379    KFR07486.1    KB030666    ELK11985.1    ATLV01013353    KE524854    KFB37733.1    IACN01079963    IACN01079967    LAB58902.1    AMGL01082902    KK817190    KFQ38701.1    MCFN01000170    OXB63336.1    JH880877    ELR58155.1    NEDP02005591    OWF37321.1    KB743435    EOA98763.1    GGMS01010264    MBY79467.1    JH169815    EHB07668.1    ACTA01043018    ACTA01051018    KE162842    EPQ09780.1    KL870627    KGL88871.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000037510    UP000053240    UP000053268    + More
UP000235965    UP000245037    UP000279307    UP000053097    UP000027135    UP000009046    UP000242457    UP000005203    UP000007755    UP000075809    UP000078492    UP000078541    UP000000673    UP000076502    UP000036403    UP000215335    UP000053825    UP000002358    UP000078540    UP000005205    UP000069272    UP000000305    UP000002320    UP000054359    UP000092461    UP000183832    UP000009136    UP000007267    UP000005447    UP000092462    UP000002494    UP000001645    UP000248483    UP000252040    UP000245320    UP000001074    UP000000715    UP000028990    UP000248484    UP000011712    UP000008227    UP000261681    UP000002254    UP000286640    UP000053605    UP000010552    UP000030765    UP000265300    UP000286642    UP000261680    UP000291021    UP000002356    UP000198323    UP000075885    UP000081671    UP000242188    UP000006813    UP000008912    UP000053858   

PRIDE

H9J824    Q6AYJ1    F1SR01   

Pfam

PF16124   RecQ_Zn_bind        + More
PF00270   DEAD
PF00271   Helicase_C
PF02759   RUN
PF09382   RQC
PF05693   Glycogen_syn

Interpro

IPR001650   Helicase_C        + More
IPR036388   WH-like_DNA-bd_sf       
IPR014001   Helicase_ATP-bd       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR004589   DNA_helicase_ATP-dep_RecQ       
IPR032284   RecQ_Zn-bd       
IPR027417   P-loop_NTPase       
IPR001478   PDZ       
IPR036034   PDZ_sf       
IPR037213   Run_dom_sf       
IPR004012   Run_dom       
IPR018982   RQC_domain       
IPR008631   Glycogen_synth       
IPR002464   DNA/RNA_helicase_DEAH_CS       

SUPFAM

SSF52540   SSF52540        + More
SSF140741   SSF140741       
SSF50156   SSF50156       

Gene 3D

1.10.10.10    

CDD

cd00079  HELICc

ProteinModelPortal

H9J824   A0A212FIK8   A0A2A4JJE6   A0A0L7LGS0   A0A194QSN4   A0A2H1WI67   + More
L7X1M6   C9S278   A0A194QAP1   E3UKN2   A0A2J7Q8Y3   A0A1B6JNR2   A0A1B6CUY3   A0A2P8YQL9   A0A1B6M5M1   A0A3L8DC02   A0A026WLE0   A0A067RX24   E0VZQ3   A0A2A3EM88   A0A087ZZI7   F4WEW0   A0A151X9X4   E9JCN0   A0A151JNL4   A0A151K1E3   W5JVH8   A0A310SCJ2   A0A154PK42   A0A0J7KYL3   A0A232FL31   A0A0L7QNC7   A0A336MJW4   A0A336L3W0   K7J5G3   A0A195B5U2   A0A158NWX1   A0A0P5DHV1   A0A182FUS3   E9G2Y5   A0A0P4VRU5   A0A0P5HZH7   A0A1Q3F0B8   A0A2J7Q8Y0   A0A0P5C8B0   B0XD44   A0A291S6Y1   A0A0P5B466   A0A087SWY7   A0A1B0CJD7   A0A1J1J5C0   A0A0C9RZJ3   A0JN36   J3S495   A0A2R5LAI8   A0A0P5ZDE8   K7F4Y8   H0VZ66   A0A0P5Z9P4   K7F4Y6   A0A1B0DNX2   Q6AYJ1   G1NLK6   A0A2Y9NEU0   A0A250YKF7   A0A341ADV5   A0A2U4BG13   T1E5X8   G1P5G3   M3XM99   A0A091ELU9   A0A2Y9FPS5   M3WQ95   A0A0B8RW48   A0A287BGJ9   A0A384B6I2   Q8AYS4   F1PNP1   A0A3Q7T7K4   A0A091X1R1   L5KKB3   A0A084VID9   A0A340WP44   A0A3Q7WV68   A0A384C948   A0A2D4PLK1   W5QGJ8   A0A091RGT0   A0A226N6V9   A0A182PC96   A0A1S3FXI9   L8INL4   A0A210PLF8   R0KZK1   A0A2S2QP09   G5BEF7   G1MCS7   F1SR01   S7N182   A0A0A0A487  

PDB

2WWY     E-value=7.23604e-158,     Score=1431

KEGG

101746968    K10899 ATP-dependent DNA helicase Q1 [EC:3.6.4.12] | (RefSeq) ATP-dependent DNA helicase Q1-like

GO

GO:0005634   GO:0008026   GO:0005524   GO:0006310   GO:0003676   GO:0004386   GO:0006268   GO:0009378   GO:0005694   GO:0005737   GO:0036310   GO:0043140   GO:0000724   GO:0006281   GO:0032508   GO:0005654   GO:0006260   GO:0003678   GO:0003677   GO:0004373   GO:0005978   GO:0008152   GO:0016301   GO:0016773   GO:0016155   GO:0003824  

PANTHER

PTHR10176  

Subcellular location

Nucleus  

Length:

629

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.53239

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02099

outside

1  -  629

 

 

Pi

317.447405

Theta

226.777179

Tajima's D

1.119952

CLR

0

CSRT

0.692765361731913

Interpretation

Uncertain