Gene

KWMTBOMO10081

Pre Gene Modal

BGIBMGA005671

Annotation

PREDICTED:_guanylate_cyclase_32E_[Amyelois_transitella]

Location

Bomo_Chr17(-):1989292-1999983      View in EpiBrowser

Full name

Guanylate cyclase       + More
Guanylate cyclase 32E      

Location in the cell

Mitochondrial   Reliability : 1.432

CDS

ATGCGAGATCTCGGTGTTTCCGCATTTTTCGGACCTGACGGAACATGCCACACTGAAGCCAAGCTAGCTGCTGCTTGGAACTTGCCTCTTATTTCTCATAAATGTACAGGAGCCCATGGTCCGATCGATGAGAATGGATCAGCTCTTGGTGCCACGTTCGCTAGGACCCTGCCTCCTGCGTACAAGGTCAGCAAATCGCTGGTCTCTCTACTGAAAGCCTTTGGCTGGACCAAATTTACTGTGGTTGCCGGAGATAACAATACACCTGCTGCTCAACAGTTGGATGCTCTCAAGAAGATTTTTATTGATTAA

Protein

MRDLGVSAFFGPDGTCHTEAKLAAAWNLPLISHKCTGAHGPIDENGSALGATFARTLPPAYKVSKSLVSLLKAFGWTKFTVVAGDNNTPAAQQLDALKKIFID

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Keywords

cGMP biosynthesis   Complete proteome   Disulfide bond   Glycoprotein   GTP-binding   Lyase   Membrane   Nucleotide-binding   Receptor   Reference proteome   Signal   Transmembrane   Transmembrane helix  

Feature

chain  Guanylate cyclase

Uniprot

H9J829   A0A2A4JP88   A0A212FFQ5   A0A194QAM5   A0A194QSQ1   A0A1B6E3D5   + More
A0A139WDI2   A0A139WDK0   A0A182H963   Q17AF9   A0A1S4FAA0   T1HNK9   A0A2R7W1J8   B4HX26   X2J5N3   B3N4K3   B4QAC0   Q07553   A0A0Q5WB16   A0A0J9R1J4   A8DYZ3   B0WPU2   A0A1B0D0D2   B4P180   A0A0R1DJU5   A0A3B0JFK9   A0A0R3NSS5   A0A1W4VT06   A0A1W4W5P4   A0A0R3NTK6   B4G9U6   B5DIL1   A0A0R3NYC5   A0A146KWY4   B3MMW4   A0A182ILP4   B4MWE1   A0A182F1Z3   A0A1B0G5I9   A0A0M4E8L4   A0A1A9Y361   A0A084VYH2   A0A182VU62   W5JRT6   A0A1A9UXC2   A0A1I8N087   A0A1I8PD95   B4LQH0   T1GWH1   A0A182MHI3   A0A182Q3F5   A0A182Y970   Q7PWU5   A0A182NP43   A0A1B0A0T9   A0A2C9GRZ6   A0A1S4H063   A0A023F3B8   A0A182XDI7   A0A182P9Q0   A0A182R498   A0A1B0BWX4   B4KHA8   R7TG30   B4JBD1   A0A1S3HFZ8   A0A2R7W8M2   C3YC81   T1IAR7   A0A2S2R4A9   V3ZIC4   A0A1W4XT11   A0A085NM74   D6X177   A0A0N5DPS5   A0A1S3HFS9   A0A1W0WG25   A0A077Z5P3   A0A0M8ZPG3   A0A1D1UL07   A0A1Y1M579   A0A0F7VHN3   A0A2H8TK31   A0A224XIA1   A0A0L7RJ80   T1G4U3   T1KKV6   A0A3L8DCZ8   A0A1B6EEF4   V5GRI8   A0A1B0CUZ5   E9HFG1   A0A067QVM8   T1EGK7   A0A1L8DJP0   A0A1L8DJG1   A0A1L8DJE6   A0A1L8DJF6  

EC Number

4.6.1.2

Pubmed

19121390    22118469    26354079    18362917    19820115    26483478    + More
17510324    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    8104831    22936249    17550304    15632085    26823975    24438588    20920257    23761445    25315136    18057021    25244985    12364791    25474469    23254933    26383154    18563158    24929829    27649274    28004739    30249741    21292972    24845553   

EMBL

BABH01020312    NWSH01000900    PCG73629.1    AGBW02008791    OWR52553.1    KQ459232    + More
KPJ02583.1    KQ461155    KPJ08349.1    GEDC01004864    JAS32434.1    KQ971357    KYB26028.1    KYB26029.1    JXUM01029951    JXUM01029952    KQ560868    KXJ80560.1    CH477336    EAT43201.1    ACPB03001838    KK854242    PTY13614.1    CH480818    EDW52571.1    AE014134    AHN54348.1    CH954177    EDV58915.1    CM000361    EDX04675.1    X72800    X72801    KQS70572.1    CM002910    KMY89709.1    ABV53670.1    DS232030    EDS32530.1    AJVK01002401    AJVK01002402    AJVK01002403    AJVK01002404    CM000157    EDW88055.1    KRJ97540.1    OUUW01000004    SPP79483.1    CH379060    KRT04270.1    KRT04268.1    CH479180    EDW29126.1    EDY70153.2    KRT04269.1    GDHC01017635    JAQ00994.1    CH902620    EDV30989.2    CH963857    EDW76011.2    CCAG010009105    CP012523    ALC39302.1    ATLV01018366    KE525231    KFB43016.1    ADMH02000358    ETN66841.1    CH940649    EDW63420.2    KRF81107.1    CAQQ02130480    CAQQ02130481    CAQQ02130482    CAQQ02130483    CAQQ02130484    AXCM01000043    AXCN02002096    AAAB01008984    EAA14802.5    APCN01003350    APCN01003351    APCN01003352    GBBI01002797    JAC15915.1    JXJN01021989    JXJN01021990    CH933807    EDW13325.2    AMQN01014569    KB311063    ELT90006.1    CH916368    EDW02936.1    KK854428    PTY15778.1    GG666500    EEN62113.1    ACPB03019543    GGMS01015560    MBY84763.1    KB203566    ESO83957.1    KL363185    KL367487    KFD58303.1    KFD70570.1    KQ971372    EFA10586.2    MTYJ01000109    OQV14132.1    HG805928    CDW54983.1    KQ435922    KOX68415.1    BDGG01000001    GAU87957.1    GEZM01043506    JAV79046.1    LN830720    CFW94229.1    GFXV01002712    MBW14517.1    GFTR01008655    JAW07771.1    KQ414582    KOC70843.1    AMQM01005284    KB096864    ESO00947.1    CAEY01000200    QOIP01000010    RLU18186.1    GEDC01007580    GEDC01000969    JAS29718.1    JAS36329.1    GALX01005588    JAB62878.1    AJWK01029883    AJWK01029884    AJWK01029885    AJWK01029886    AJWK01029887    AJWK01029888    AJWK01029889    GL732635    EFX69540.1    KK853196    KDR09972.1    AMQM01009100    KB095940    ESO09672.1    GFDF01007499    JAV06585.1    GFDF01007498    JAV06586.1    GFDF01007496    JAV06588.1    GFDF01007501    JAV06583.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000007266    + More
UP000069940    UP000249989    UP000008820    UP000015103    UP000001292    UP000000803    UP000008711    UP000000304    UP000002320    UP000092462    UP000002282    UP000268350    UP000001819    UP000192221    UP000008744    UP000007801    UP000075880    UP000007798    UP000069272    UP000092444    UP000092553    UP000092443    UP000030765    UP000075920    UP000000673    UP000078200    UP000095301    UP000095300    UP000008792    UP000015102    UP000075883    UP000075886    UP000076408    UP000007062    UP000075884    UP000092445    UP000075840    UP000076407    UP000075885    UP000075900    UP000092460    UP000009192    UP000014760    UP000001070    UP000085678    UP000001554    UP000030746    UP000192223    UP000046395    UP000030665    UP000053105    UP000186922    UP000053825    UP000015101    UP000015104    UP000279307    UP000092461    UP000000305    UP000027135   

PRIDE

H9J829    X2J5N3    Q07553   

Pfam

PF01094   ANF_receptor        + More
PF00211   Guanylate_cyc
PF07714   Pkinase_Tyr
PF02826   2-Hacid_dh_C
PF17681   GCP_N_terminal
PF04130   GCP_C_terminal
PF00389   2-Hacid_dh
PF07701   HNOBA
PF00069   Pkinase
PF12796   Ank_2

Interpro

IPR028082   Peripla_BP_I        + More
IPR001828   ANF_lig-bd_rcpt       
IPR001054   A/G_cyclase       
IPR000719   Prot_kinase_dom       
IPR029787   Nucleotide_cyclase       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR018297   A/G_cyclase_CS       
IPR001170   ANPR/GUC       
IPR041470   GCP_N       
IPR029752   D-isomer_DH_CS1       
IPR029753   D-isomer_DH_CS       
IPR006139   D-isomer_2_OHA_DH_cat_dom       
IPR006140   D-isomer_DH_NAD-bd       
IPR036291   NAD(P)-bd_dom_sf       
IPR042241   GCP_C_sf       
IPR040457   GCP_C       
IPR011645   HNOB_dom_associated       
IPR036770   Ankyrin_rpt-contain_sf       
IPR020683   Ankyrin_rpt-contain_dom       
IPR002110   Ankyrin_rpt       
IPR000337   GPCR_3       

SUPFAM

SSF53822   SSF53822        + More
SSF55073   SSF55073       
SSF56112   SSF56112       
SSF51735   SSF51735       
SSF48403   SSF48403       

Gene 3D

3.30.70.1230     1.20.120.1900     1.25.40.20    

CDD

cd00204  ANK

ProteinModelPortal

H9J829   A0A2A4JP88   A0A212FFQ5   A0A194QAM5   A0A194QSQ1   A0A1B6E3D5   + More
A0A139WDI2   A0A139WDK0   A0A182H963   Q17AF9   A0A1S4FAA0   T1HNK9   A0A2R7W1J8   B4HX26   X2J5N3   B3N4K3   B4QAC0   Q07553   A0A0Q5WB16   A0A0J9R1J4   A8DYZ3   B0WPU2   A0A1B0D0D2   B4P180   A0A0R1DJU5   A0A3B0JFK9   A0A0R3NSS5   A0A1W4VT06   A0A1W4W5P4   A0A0R3NTK6   B4G9U6   B5DIL1   A0A0R3NYC5   A0A146KWY4   B3MMW4   A0A182ILP4   B4MWE1   A0A182F1Z3   A0A1B0G5I9   A0A0M4E8L4   A0A1A9Y361   A0A084VYH2   A0A182VU62   W5JRT6   A0A1A9UXC2   A0A1I8N087   A0A1I8PD95   B4LQH0   T1GWH1   A0A182MHI3   A0A182Q3F5   A0A182Y970   Q7PWU5   A0A182NP43   A0A1B0A0T9   A0A2C9GRZ6   A0A1S4H063   A0A023F3B8   A0A182XDI7   A0A182P9Q0   A0A182R498   A0A1B0BWX4   B4KHA8   R7TG30   B4JBD1   A0A1S3HFZ8   A0A2R7W8M2   C3YC81   T1IAR7   A0A2S2R4A9   V3ZIC4   A0A1W4XT11   A0A085NM74   D6X177   A0A0N5DPS5   A0A1S3HFS9   A0A1W0WG25   A0A077Z5P3   A0A0M8ZPG3   A0A1D1UL07   A0A1Y1M579   A0A0F7VHN3   A0A2H8TK31   A0A224XIA1   A0A0L7RJ80   T1G4U3   T1KKV6   A0A3L8DCZ8   A0A1B6EEF4   V5GRI8   A0A1B0CUZ5   E9HFG1   A0A067QVM8   T1EGK7   A0A1L8DJP0   A0A1L8DJG1   A0A1L8DJE6   A0A1L8DJF6  

PDB

6B7H     E-value=0.00585664,     Score=86

KEGG

NA   

GO

GO:0016021   GO:0005524   GO:0004383   GO:0004672   GO:0035556   GO:0005886   GO:0007165   GO:0006468   GO:0019934   GO:0038023   GO:0005887   GO:0005525   GO:0016616   GO:0043015   GO:0051287   GO:0006182   GO:0007168   GO:0001653   GO:0004930   GO:0000166  

Subcellular location

Membrane  

Length:

103

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00805

Exp number, first 60 AAs:

0.0006

Total prob of N-in:

0.07714

outside

1  -  103

 

 

Pi

21.670647

Theta

192.77056

Tajima's D

-1.177429

CLR

0.323563

CSRT

0.105694715264237

Interpretation

Possibly Positive selection