Gene

KWMTBOMO10078

Annotation

PREDICTED:_guanylate_cyclase_32E_[Amyelois_transitella]

Location

Bomo_Chr17(-):1960845-1968713      View in EpiBrowser

Full name

Guanylate cyclase       + More
Guanylate cyclase 32E      

Location in the cell

Extracellular   Reliability : 1.623 PlasmaMembrane   Reliability : 1.112

CDS

ATGTTTTTTGTTACAGTATACGTGTTCCTGGGCGAACACATAGCGCTTGTCGACTTCGTAAACGTGCTGGAGAAACGGGGATTGCTCGCTACAGGAAACTATGCAGTTGTCGCTGTCGACGATGAGATCTATGACCCTAACACCACAGCCGTGACTTATGCTGATCATCTCGGAAAAAACCGCACCAACGACATAACTGCGTTCAGGTCTGTCCTGAGACTCACGCCTTCGTTCCCAACGAATCCTCATTACGAGATCCTTTGTCAAATGATCAGGGAGCTCTCGGCCGTGCCACCATTCTGCGTTCCGAACTATCACAAGATCTTCGAAGATGCCTCGGGATAA

Protein

MFFVTVYVFLGEHIALVDFVNVLEKRGLLATGNYAVVAVDDEIYDPNTTAVTYADHLGKNRTNDITAFRSVLRLTPSFPTNPHYEILCQMIRELSAVPPFCVPNYHKIFEDASG

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Keywords

cGMP biosynthesis   Complete proteome   Disulfide bond   Glycoprotein   GTP-binding   Lyase   Membrane   Nucleotide-binding   Receptor   Reference proteome   Signal   Transmembrane   Transmembrane helix  

Feature

chain  Guanylate cyclase

Uniprot

A0A194QSQ1   A0A194QAM5   A0A2A4JP88   A0A139WDI2   A0A139WDK0   T1HNK9   + More
A0A146KWY4   A0A067RMP4   A0A2P8XXW2   E0W2G4   B4LQH0   B4KHA8   N6TFV7   A0A1B0D0D2   A0A0N8E865   A0A0P5CQL6   A0A0P5CN85   A0A0N8CLV3   A0A0P5WH20   A0A0P6BHS8   A0A0P5EGZ5   A0A0P4YXA1   A0A0P6G379   A0A0N8A6H0   A0A0P4ZRW1   A0A0P5WUA0   A0A0P5B5W5   A0A0P5UHG3   A0A0P6HWV4   A0A0P6G382   A0A0P5DR45   A0A164Q4I2   A0A0P5DGF2   A0A0P5D5R6   A0A0P5VEM9   A0A2R7WWS8   A0A3B0JFK9   B5DIL1   A0A0R3NYC5   A0A0R1DJU5   A0A0R3NTK6   A0A1A9UXC2   A0A1B0BWX4   A0A1B0A0T9   A0A0J9R1J4   A0A1B0FQA5   A0A1W4W5P4   A0A0Q5WB16   A8DYZ3   B3MMW4   B4MWE1   A0A1I8PD95   A0A084VYH2   A0A182F1Z3   W5JRT6   A0A182ILP4   A0A0L0BZE8   A0A182Y970   A0A182Q3F5   A0A182NP43   A0A182R498   A0A0P5CS31   A0A1I8NG04   A0A182VBW3   A0A182VU62   A0A1S4H063   A0A182XDI7   A0A2C9GRZ6   A0A182U4U3   A0A182KNH9   A0A0M4E8L4   Q7PWU5   B0WPU2   A0A1S4FAA0   A0A182H963   A0A0P5LTI7   A0A0P5QU44   A0A0P6FWN6   A0A0P5PAZ8   A0A0P5ZAY1   A0A0P5DI19   A0A0P5RTM9   A0A0P6DLI3   A0A0P6B8G8   A0A0N8BNB3   A0A0N8EM03   A0A0P5NXS8   A0A182P9Q0   A0A182SNN7   A0A1A9Y362   B4P180   B4HX26   B4QAC0   B3N4K3   Q07553   Q17AF9   B4G9U6   B4JBD1   A0A162R3A0  

EC Number

4.6.1.2

Pubmed

26354079    18362917    19820115    26823975    24845553    29403074    + More
20566863    17994087    18057021    23537049    15632085    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    24438588    20920257    23761445    26108605    25244985    25315136    12364791    20966253    17510324    26483478    8104831   

EMBL

KQ461155    KPJ08349.1    KQ459232    KPJ02583.1    NWSH01000900    PCG73629.1    + More
KQ971357    KYB26028.1    KYB26029.1    ACPB03001838    GDHC01017635    JAQ00994.1    KK852421    KDR24308.1    PYGN01001181    PSN36852.1    DS235878    EEB19820.1    CH940649    EDW63420.2    KRF81107.1    CH933807    EDW13325.2    APGK01039614    APGK01039615    APGK01039616    KB740972    ENN76628.1    AJVK01002401    AJVK01002402    AJVK01002403    AJVK01002404    GDIQ01052348    JAN42389.1    GDIP01166914    JAJ56488.1    GDIP01167810    JAJ55592.1    GDIP01119023    JAL84691.1    GDIP01086478    JAM17237.1    GDIP01014364    JAM89351.1    GDIP01160124    JAJ63278.1    GDIP01222214    JAJ01188.1    GDIQ01039146    JAN55591.1    GDIP01177777    JAJ45625.1    GDIP01222213    GDIP01222212    JAJ01189.1    GDIP01081672    JAM22043.1    GDIP01189168    JAJ34234.1    GDIP01112873    JAL90841.1    GDIQ01014350    JAN80387.1    GDIQ01039147    JAN55590.1    GDIP01158720    JAJ64682.1    LRGB01002475    KZS07425.1    GDIP01160123    JAJ63279.1    GDIP01160822    JAJ62580.1    GDIP01102876    JAM00839.1    KK855823    PTY23999.1    OUUW01000004    SPP79483.1    CH379060    EDY70153.2    KRT04269.1    CM000157    KRJ97540.1    KRT04268.1    JXJN01021989    JXJN01021990    CM002910    KMY89709.1    CCAG010004953    CH954177    KQS70572.1    AE014134    ABV53670.1    CH902620    EDV30989.2    CH963857    EDW76011.2    ATLV01018366    KE525231    KFB43016.1    ADMH02000358    ETN66841.1    JRES01001119    KNC25378.1    AXCN02002096    GDIP01166215    JAJ57187.1    AAAB01008984    APCN01003350    APCN01003351    APCN01003352    CP012523    ALC39302.1    EAA14802.5    DS232030    EDS32530.1    JXUM01029951    JXUM01029952    KQ560868    KXJ80560.1    GDIQ01168500    JAK83225.1    GDIQ01129872    JAL21854.1    GDIQ01053087    JAN41650.1    GDIQ01131119    JAL20607.1    GDIP01046329    JAM57386.1    GDIP01157172    JAJ66230.1    GDIQ01097368    JAL54358.1    GDIQ01085077    JAN09660.1    GDIP01020457    JAM83258.1    GDIQ01160955    JAK90770.1    GDIQ01013644    JAN81093.1    GDIQ01136266    JAL15460.1    EDW88055.1    CH480818    EDW52571.1    CM000361    EDX04675.1    EDV58915.1    X72800    X72801    CH477336    EAT43201.1    CH479180    EDW29126.1    CH916368    EDW02936.1    LRGB01000243    KZS20192.1   

Proteomes

UP000053240    UP000053268    UP000218220    UP000007266    UP000015103    UP000027135    + More
UP000245037    UP000009046    UP000008792    UP000009192    UP000019118    UP000092462    UP000076858    UP000268350    UP000001819    UP000002282    UP000078200    UP000092460    UP000092445    UP000092444    UP000192221    UP000008711    UP000000803    UP000007801    UP000007798    UP000095300    UP000030765    UP000069272    UP000000673    UP000075880    UP000037069    UP000076408    UP000075886    UP000075884    UP000075900    UP000095301    UP000075903    UP000075920    UP000076407    UP000075840    UP000075902    UP000075882    UP000092553    UP000007062    UP000002320    UP000069940    UP000249989    UP000075885    UP000075901    UP000092443    UP000001292    UP000000304    UP000008820    UP000008744    UP000001070   

PRIDE

Q07553   

Pfam

PF01094   ANF_receptor        + More
PF00211   Guanylate_cyc
PF07714   Pkinase_Tyr
PF07701   HNOBA
PF00069   Pkinase
PF00389   2-Hacid_dh
PF02826   2-Hacid_dh_C
PF17681   GCP_N_terminal
PF04130   GCP_C_terminal

Interpro

IPR011009   Kinase-like_dom_sf        + More
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR001828   ANF_lig-bd_rcpt       
IPR029787   Nucleotide_cyclase       
IPR000719   Prot_kinase_dom       
IPR001054   A/G_cyclase       
IPR028082   Peripla_BP_I       
IPR018297   A/G_cyclase_CS       
IPR001170   ANPR/GUC       
IPR011645   HNOB_dom_associated       
IPR008266   Tyr_kinase_AS       
IPR036291   NAD(P)-bd_dom_sf       
IPR006140   D-isomer_DH_NAD-bd       
IPR006139   D-isomer_2_OHA_DH_cat_dom       
IPR029753   D-isomer_DH_CS       
IPR029752   D-isomer_DH_CS1       
IPR041470   GCP_N       
IPR042241   GCP_C_sf       
IPR040457   GCP_C       

SUPFAM

SSF56112   SSF56112        + More
SSF55073   SSF55073       
SSF53822   SSF53822       
SSF51735   SSF51735       

Gene 3D

3.30.70.1230     1.20.120.1900    

ProteinModelPortal

A0A194QSQ1   A0A194QAM5   A0A2A4JP88   A0A139WDI2   A0A139WDK0   T1HNK9   + More
A0A146KWY4   A0A067RMP4   A0A2P8XXW2   E0W2G4   B4LQH0   B4KHA8   N6TFV7   A0A1B0D0D2   A0A0N8E865   A0A0P5CQL6   A0A0P5CN85   A0A0N8CLV3   A0A0P5WH20   A0A0P6BHS8   A0A0P5EGZ5   A0A0P4YXA1   A0A0P6G379   A0A0N8A6H0   A0A0P4ZRW1   A0A0P5WUA0   A0A0P5B5W5   A0A0P5UHG3   A0A0P6HWV4   A0A0P6G382   A0A0P5DR45   A0A164Q4I2   A0A0P5DGF2   A0A0P5D5R6   A0A0P5VEM9   A0A2R7WWS8   A0A3B0JFK9   B5DIL1   A0A0R3NYC5   A0A0R1DJU5   A0A0R3NTK6   A0A1A9UXC2   A0A1B0BWX4   A0A1B0A0T9   A0A0J9R1J4   A0A1B0FQA5   A0A1W4W5P4   A0A0Q5WB16   A8DYZ3   B3MMW4   B4MWE1   A0A1I8PD95   A0A084VYH2   A0A182F1Z3   W5JRT6   A0A182ILP4   A0A0L0BZE8   A0A182Y970   A0A182Q3F5   A0A182NP43   A0A182R498   A0A0P5CS31   A0A1I8NG04   A0A182VBW3   A0A182VU62   A0A1S4H063   A0A182XDI7   A0A2C9GRZ6   A0A182U4U3   A0A182KNH9   A0A0M4E8L4   Q7PWU5   B0WPU2   A0A1S4FAA0   A0A182H963   A0A0P5LTI7   A0A0P5QU44   A0A0P6FWN6   A0A0P5PAZ8   A0A0P5ZAY1   A0A0P5DI19   A0A0P5RTM9   A0A0P6DLI3   A0A0P6B8G8   A0A0N8BNB3   A0A0N8EM03   A0A0P5NXS8   A0A182P9Q0   A0A182SNN7   A0A1A9Y362   B4P180   B4HX26   B4QAC0   B3N4K3   Q07553   Q17AF9   B4G9U6   B4JBD1   A0A162R3A0  

KEGG

NA   

GO

GO:0005524   GO:0004383   GO:0004672   GO:0035556   GO:0016021   GO:0005886   GO:0007165   GO:0016616   GO:0051287   GO:0043015   GO:0006468   GO:0019934   GO:0038023   GO:0005887   GO:0005525  

Subcellular location

Membrane  

Length:

114

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.42363

Exp number, first 60 AAs:

0.42345

Total prob of N-in:

0.04705

outside

1  -  114

 

 

Pi

191.050775

Theta

152.786834

Tajima's D

1.695688

CLR

0.44716

CSRT

0.833858307084646

Interpretation

Uncertain