Gene

KWMTBOMO10047  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005686

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_tuberin_[Bombyx_mori]

Location

Bomo_Chr17(-):844401-851489      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.745 PlasmaMembrane   Reliability : 1.139

CDS

ATGGGGTCTAGGGACAGGGACTCGAAATCGCTACAGGACAAGCTGAAAGTGTTCTTCAAGAAAGGTGCATCGGCGCCGCTAGCGGCTCGCAGCGAGCTGGTGTCGAAGGAGGTGCTTCATGAGTTGAGCGTCGAAACGCCGCTGCACCGACGGCTCCGTGCCATGAAGGATGTTGGCGACAAGGTCATTCAGGGACGCGTGGAAGACGGTGGTGTTGAAAAGTTATGGTCTTGCACTCGAGACCTCCTCTACACGGATAATACCGAAGCCCGTCACACAGCCCTGTGTTTCATGAGATGTATCGCTGAAGGACAAGCAGAAGATCTACAAATAATGAGGACAATTTTCTTCAAATTCCTAAGGGAGACACACCCGTCTCATCCGCCAGACGACTATCAATTACGCTTTAAACTACTCTATACATTGACTAATAGCGGGAAAAATATTAATTGTTTTGAAGTGGATATTGGAGAGTTCTTATTGGAATGGCTGCCTCAAATTCAGACACCATCAAATACAGTTGAATTTTTACAGCTAATCGTAAATGTAGTAAAATTCAATGCTACATATCTGGACGAACACATTGTACATGGAATTGTCAACAACGCATGCCACTTGTGCGTATATTCCCCGGAGGTGACAGTTGTGCAGCAGTGCCTCTCCTTGCTCGAGGCTGTCGTGTCGTACTCGCTGTTGCCCCGGGCGTCCCTGCCGACGTTTGTCGGTGCGCTGTGCCGGACTGTCAACATGGAACACTACTGTCAAAATAGTTGGAAGTTGATGCGGTACGTGGTGGGCGGAGACATCGGTCCGGCGGCCGTGCAGCAGATGGTGTCGCTGCTGCAGTCGGGGGCGGAGGCCGGGGCTGCCAGGGGCGCCGTGTTCTATATCAACATGGCACTGTGGGGGCCGCAACGTGTGCCCACGCTCAAGGTGTCATTTCTGGCCGTCCTACCGGCCTTTCTGAAGGCGCTGGAGGGTCGCCAGGCGGTGGTGGCGTACGAGGTGGTGGTGGGGGTGGCCAGCGTGGTCACGCGAGCCCCCCACGAGCTGTACGAGCCGGCCTGGGACGTGCTGCTGAGGATCGTGCGAACCCTGCTGCAGCTCGACAAATCGTACGACCCCCCCAACGACTTGATGCACTCCCGGCTGCACAACATCATAACGTCGATCGAACAACTCCAGGAGTCCGGCCAGTACAAGGGCGACGCGGAGGCCCTGCTGGACCTCGTGGACAGCTGCGGACACGAGCGCCCGTTGACCCTTCAGACTTCGTAG

Protein

MGSRDRDSKSLQDKLKVFFKKGASAPLAARSELVSKEVLHELSVETPLHRRLRAMKDVGDKVIQGRVEDGGVEKLWSCTRDLLYTDNTEARHTALCFMRCIAEGQAEDLQIMRTIFFKFLRETHPSHPPDDYQLRFKLLYTLTNSGKNINCFEVDIGEFLLEWLPQIQTPSNTVEFLQLIVNVVKFNATYLDEHIVHGIVNNACHLCVYSPEVTVVQQCLSLLEAVVSYSLLPRASLPTFVGALCRTVNMEHYCQNSWKLMRYVVGGDIGPAAVQQMVSLLQSGAEAGAARGAVFYINMALWGPQRVPTLKVSFLAVLPAFLKALEGRQAVVAYEVVVGVASVVTRAPHELYEPAWDVLLRIVRTLLQLDKSYDPPNDLMHSRLHNIITSIEQLQESGQYKGDAEALLDLVDSCGHERPLTLQTS

Uniprot

A0A2W1BH62   A0A2A4JAJ7   A0A212FF76   A0A194QAG3   A0A0L7LRT4   A0A0N1IQ05   + More
A0A2H1VXQ9   A0A2P8YFZ1   A0A2J7PKX2   A0A067R1A4   A0A1B6CHU9   A0A0N7Z993   A0A0C9QWE4   A0A154P5U1   A0A2A3E2S5   A0A088ADA5   A0A026VUB2   A0A151WRN0   A0A158NUP5   F4WRA9   A0A151IG77   A0A0M4M1C4   A0A151IS99   A0A2B4S1N1   E2AD21   K7IN19   A0A232F0T6   N6TJ61   A0A2R7WND5   A0A1B6KY98   A0A0A9XDX4   A0A1S3HHV4   A0A0K8TBU2   A0A195FK85   C3Z790   U4UEW8   E0VSQ1   A0A195BBK3   A0A3L8DJ68   A0A1B6G2M3   A0A2C9KD24   A0A2R8YEJ8   A0A1V1FNX1   X5DRC8   K1QPU2   D6WZ21   A0A3B3REN6   A0A3B3RCX5   A0A3B3RD40   A0A3B3RCF9   A0A287A4I9   F1RFB2   A0A287ACI2   A0A287AG89   A0A287ADS4   A0A287BTB9   A0A2K6RI22   X5D7Z6   A0A287BBA5   A0A287BG63   X5D9K3   A0A2R9B2X2   Q3UI96   A0A1V1FFQ4   A0A2K5ZR95   A0A2K5V7X6   A0A3Q2IBY1   A0A1D5QQI8   A0A3Q2H0W3   A0A2I3M4Y1   F6WI30   A0A3Q2L218   A0A091DWS9   A0A2K5MV13   A0A1V1G0D9   F6ZQU1   W5M5E7   W5M5G2   A0A2Y9SP68   A0A2Y9EDW4   A0A1V1FNX9   A0A1V1FI06   A0A2Y9EE39   A0A2K6RI55   A0A2Y9PYI6   A0A2Y9Q480   A0A2Y9PTM1   L5LUJ4   A0A341CM49   A0A2Y9Q484   A0A2K6RI03   A0A2Y9PYI2   A0A341CLG7   A0A341CLE4   A0A2Y9PXK2   A0A1S3WIC2   A0A2K5MVI9   A0A1S3WHM3   A0A1S3A201  

Pubmed

28756777    22118469    26354079    26227816    29403074    24845553    + More
27129103    24508170    21347285    21719571    20798317    20075255    28648823    23537049    25401762    18563158    20566863    30249741    15562597    15616553    21269460    24722188    22992520    18362917    19820115    29240929    30723633    25362486    22722832    10349636    11042159    11076861    11217851    12466851    16141073    19892987    17431167    18464734   

EMBL

KZ150179    PZC72537.1    NWSH01002371    PCG68450.1    AGBW02008849    OWR52395.1    + More
KQ459232    KPJ02523.1    JTDY01000229    KOB78178.1    KQ460044    KPJ18291.1    ODYU01005093    SOQ45627.1    PYGN01000627    PSN43169.1    NEVH01024531    PNF16986.1    KK852784    KDR16585.1    GEDC01024280    JAS13018.1    GDKW01001187    JAI55408.1    GBYB01000035    JAG69802.1    KQ434823    KZC07296.1    KZ288467    PBC25401.1    KK107942    EZA47091.1    KQ982806    KYQ50457.1    ADTU01026650    ADTU01026651    ADTU01026652    GL888284    EGI63326.1    KQ977739    KYN00227.1    KR075843    ALE20562.1    KQ981085    KYN09595.1    LSMT01000223    PFX22959.1    GL438658    EFN68657.1    NNAY01001310    OXU24396.1    APGK01035639    KB740928    ENN77893.1    KK855147    PTY21138.1    GEBQ01023743    JAT16234.1    GBHO01025435    JAG18169.1    GBRD01003191    JAG62630.1    KQ981512    KYN40813.1    GG666590    EEN51686.1    KB632064    ERL88460.1    DS235755    EEB16407.1    KQ976532    KYM81590.1    QOIP01000007    RLU20252.1    GECZ01013082    JAS56687.1    AC093513    LC224282    BAX02962.1    KJ534982    AHW56622.1    JH818015    EKC33134.1    KQ971363    EFA09042.2    AEMK02000018    DQIR01165177    HDB20654.1    KJ535091    AHW56730.1    KJ535039    AHW56678.1    AJFE02022693    AJFE02022694    AK147016    BAE27610.1    LC224288    BAX02968.1    AQIA01041640    AQIA01041641    AQIA01041642    AQIA01041643    AQIA01041644    JSUE03025444    JSUE03025445    JSUE03025446    JSUE03025447    AHZZ02018195    KN121905    KFO34715.1    LC224283    LC224290    BAX02963.1    AHAT01037171    LC224292    BAX02972.1    LC224289    BAX02969.1    KB107323    ELK30094.1   

Proteomes

UP000218220    UP000007151    UP000053268    UP000037510    UP000053240    UP000245037    + More
UP000235965    UP000027135    UP000076502    UP000242457    UP000005203    UP000053097    UP000075809    UP000005205    UP000007755    UP000078542    UP000078492    UP000225706    UP000000311    UP000002358    UP000215335    UP000019118    UP000085678    UP000078541    UP000001554    UP000030742    UP000009046    UP000078540    UP000279307    UP000076420    UP000005640    UP000005408    UP000007266    UP000261540    UP000008227    UP000233200    UP000240080    UP000233140    UP000233100    UP000002281    UP000006718    UP000028761    UP000028990    UP000233060    UP000002279    UP000018468    UP000248484    UP000248483    UP000252040    UP000079721   

PRIDE

F1RFB2    X5D7Z6    X5D9K3   

Pfam

PF02145   Rap_GAP        + More
PF03542   Tuberin
PF11864   DUF3384
PF02985   HEAT

Interpro

IPR000331   Rap_GAP_dom        + More
IPR035974   Rap/Ran-GAP_sf       
IPR016024   ARM-type_fold       
IPR003913   Tuberin       
IPR024584   Tuberin_N       
IPR018515   Tuberin-type_domain       
IPR027107   Tuberin/Ral-act_asu       
IPR011989   ARM-like       
IPR021133   HEAT_type_2       
IPR000357   HEAT       

SUPFAM

SSF48371   SSF48371        + More
SSF111347   SSF111347       

Gene 3D

3.40.50.11210     1.25.10.10    

ProteinModelPortal

A0A2W1BH62   A0A2A4JAJ7   A0A212FF76   A0A194QAG3   A0A0L7LRT4   A0A0N1IQ05   + More
A0A2H1VXQ9   A0A2P8YFZ1   A0A2J7PKX2   A0A067R1A4   A0A1B6CHU9   A0A0N7Z993   A0A0C9QWE4   A0A154P5U1   A0A2A3E2S5   A0A088ADA5   A0A026VUB2   A0A151WRN0   A0A158NUP5   F4WRA9   A0A151IG77   A0A0M4M1C4   A0A151IS99   A0A2B4S1N1   E2AD21   K7IN19   A0A232F0T6   N6TJ61   A0A2R7WND5   A0A1B6KY98   A0A0A9XDX4   A0A1S3HHV4   A0A0K8TBU2   A0A195FK85   C3Z790   U4UEW8   E0VSQ1   A0A195BBK3   A0A3L8DJ68   A0A1B6G2M3   A0A2C9KD24   A0A2R8YEJ8   A0A1V1FNX1   X5DRC8   K1QPU2   D6WZ21   A0A3B3REN6   A0A3B3RCX5   A0A3B3RD40   A0A3B3RCF9   A0A287A4I9   F1RFB2   A0A287ACI2   A0A287AG89   A0A287ADS4   A0A287BTB9   A0A2K6RI22   X5D7Z6   A0A287BBA5   A0A287BG63   X5D9K3   A0A2R9B2X2   Q3UI96   A0A1V1FFQ4   A0A2K5ZR95   A0A2K5V7X6   A0A3Q2IBY1   A0A1D5QQI8   A0A3Q2H0W3   A0A2I3M4Y1   F6WI30   A0A3Q2L218   A0A091DWS9   A0A2K5MV13   A0A1V1G0D9   F6ZQU1   W5M5E7   W5M5G2   A0A2Y9SP68   A0A2Y9EDW4   A0A1V1FNX9   A0A1V1FI06   A0A2Y9EE39   A0A2K6RI55   A0A2Y9PYI6   A0A2Y9Q480   A0A2Y9PTM1   L5LUJ4   A0A341CM49   A0A2Y9Q484   A0A2K6RI03   A0A2Y9PYI2   A0A341CLG7   A0A341CLE4   A0A2Y9PXK2   A0A1S3WIC2   A0A2K5MVI9   A0A1S3WHM3   A0A1S3A201  

PDB

5HIU     E-value=1.1892e-06,     Score=126

KEGG

101745506    K07207 tuberous sclerosis 2 | (RefSeq) tuberin

PATHWAY

04140    Autophagy - animal - Bombyx mori (domestic silkworm)
04150    mTOR signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0033596   GO:0051056   GO:0005096   GO:0032007   GO:0005634   GO:0016021   GO:0046627   GO:0051726   GO:0030178   GO:0005737   GO:0051898   GO:0048471   GO:0042803   GO:0016020   GO:0031267   GO:0014069   GO:0043276   GO:0005764   GO:0051879   GO:0005794   GO:0016239   GO:0019902   GO:0005488   GO:0043547   GO:0004672   GO:0030677   GO:0016155   GO:0003824  

PANTHER

PTHR10063  

Length:

425

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04245

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01957

outside

1  -  425

 

 

Pi

141.112774

Theta

140.856418

Tajima's D

-0.760019

CLR

0.15025

CSRT

0.186490675466227

Interpretation

Uncertain