Gene

KWMTBOMO10041  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005687

Annotation

Phosphomannomutase_[Operophtera_brumata]

Location

Bomo_Chr17(-):797350-798159      View in EpiBrowser

Full name

Phosphomannomutase      

Location in the cell

Cytoplasmic   Reliability : 2.123 Nuclear   Reliability : 2.215

CDS

ATGACTAGTCAAAAGAAAGTTTTGTATTTGTTCGATGTTGACGGAACGTTGACAAAACCGCGCCAAAAAATTACAGAAGAATTCAGGAGGTTCATTCTTGACGAGGTAAAATCAAAAGTGGATGTAGGATTGGTCAGTGGTTCAGATTATATGAAGATTTCCGAACAAATGGGCGGAGAGGACGTCGTGTCCAATTTCAACTACGTATTCAGTGAAAATGGACTGGTGCATCATAAGAACGGAAAAAAATTAAGTTCAGAGAGCATAGTTAACCATTTGGGTGAACAAAAACTGCAAGAGGTAATAAACTTCGCCATGGGTTACATGTCCAACATCAAATTACCAGTCAAGAGAGGTAATTTCATTGAATTCCGATCAAGTATGCTTAATATTTGCCCTGTTGGAAGATCATGTAATCAAATAGAGCGAGATCAGTTTTCTGAGTATGATTCAAAACACAAAGTTAGGCACCAATTTGTTGAAGCACTTCAAAGCAAGTTCAAAGACTCGGGTTTAAAGTTTGCTCTAGGAGGTCAAATCAGTATTGATGTGTTCCCAATTGGATGGGACAAGACATACTGCTTAAATCACATAGCTAGTGAGAATTTTGCTGAAATTCACTTCTTTGGAGACAAAACAGACCCTGGTGGGAATGATCATGAAATTTACAATGACTCTAGGACTGTGGGACACAGAGTCTCATCTCCAAGTGACACTGAAATGCAAGTAAAAAAATGTCTTAATGTGGAATAG

Protein

MTSQKKVLYLFDVDGTLTKPRQKITEEFRRFILDEVKSKVDVGLVSGSDYMKISEQMGGEDVVSNFNYVFSENGLVHHKNGKKLSSESIVNHLGEQKLQEVINFAMGYMSNIKLPVKRGNFIEFRSSMLNICPVGRSCNQIERDQFSEYDSKHKVRHQFVEALQSKFKDSGLKFALGGQISIDVFPIGWDKTYCLNHIASENFAEIHFFGDKTDPGGNDHEIYNDSRTVGHRVSSPSDTEMQVKKCLNVE

Description

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

Catalytic Activity

alpha-D-mannose 1-phosphate = D-mannose 6-phosphate

Subunit

Homodimer.

Similarity

Belongs to the eukaryotic PMM family.

Uniprot

H9J845   A0A2W1BB19   A0A2A4JJZ2   A0A0L7LSL4   S4PMU4   I4DK74   + More
A0A2H1WVB5   A0A2I9LPG3   A0A1S3HCV3   A0A1S3KEL4   E9HCF1   A0A1B6DIM5   A0A0P4WB28   A0A2P8YKY2   V4BAW4   C3YWF0   D6WXJ2   A0A0P6BS41   A0A0P5R453   A0A2J7RAT9   A0A2J7RAU5   A0A0T6AZ43   A0A1B6G4M1   A0A1B6M126   A0A210QWA3   H2YEQ1   A0A1W4WZA5   A0A1V9XHX8   A0A2T7PYN3   A0A1B6IJL6   A0A1Y1LQR5   J9JYE1   A0A2P2I7N5   A0A0P6HUS4   A0A369RZY6   B3RMY2   C4WU27   A0A087UM49   A0A1Q3F690   F6SS61   A0A1W2WPB5   B0WHH5   A0A0K8R750   V5GG89   J3JVF0   G1KD11   A0A131XZ82   A0A023FY01   A0A0C9S225   A0A0P4VUS9   R4FJZ3   A0A1E1X9L8   T1KR88   B7QIG2   H2THT1   U5EKG9   A0A131XDM1   V8P3L0   A0A023GGU3   H9H6Z7   G3MPQ8   A0A131YIZ8   A0A182GCZ4   A0A1W4UVF1   A0A212FF79   T1D9U4   A0A224Z5T5   A0A023FHX0   A0A1D5PQW2   E2A6X8   H2RJ98   A0A023ELB7   A0A195C1U8   A0A151NHF5   A0A1J1IHA7   A0A182GNB4   A0A1V4JB57   A0A0N0PDS2   A0A1W7REV7   A0A0F7Z640   Q0IEM8   A0A183QQP1   A0A218UZV2   A0A293LZ40   Q6GNE0   J3S998   U3FWE0   A0A2P4W7H3   A0A194QAS7   A0A2P6K547   A0A182LXJ3   G1NY02   A0A1B0CL90   A0A3Q7RBJ5   A0A2Y9KEQ3   H0ZHY9   A0A1L8GGM9   A0A2D4M6K7   A0A287D5V8   A0A1S4FMN1  

EC Number

5.4.2.8

Pubmed

19121390    28756777    26227816    23622113    22651552    29248469    + More
21292972    29403074    23254933    18563158    18362917    19820115    28812685    28327890    28004739    30042472    18719581    12481130    15114417    22516182    23537049    26131772    27129103    28503490    21551351    28049606    24297900    17495919    22216098    26830274    26483478    22118469    23758969    28797301    15592404    20798317    24945155    22293439    26354079    26358130    17510324    23025625    23915248    26114425    26394399    21993624    20360741    27762356   

EMBL

BABH01020426    KZ150179    PZC72532.1    NWSH01001312    PCG71743.1    JTDY01000229    + More
KOB78176.1    GAIX01003375    JAA89185.1    AK401692    BAM18314.1    ODYU01011325    SOQ57001.1    GFWZ01000283    MBW20273.1    GL732619    EFX70619.1    GEDC01011747    JAS25551.1    GDRN01067174    GDRN01067172    GDRN01067171    GDRN01067169    JAI64412.1    PYGN01000522    PSN44908.1    KB200109    ESP03112.1    GG666561    EEN55194.1    KQ971361    EFA07975.2    GDIP01010451    JAM93264.1    GDIQ01203822    GDIQ01105748    JAL45978.1    NEVH01006564    PNF37953.1    PNF37954.1    LJIG01022525    KRT80117.1    GECZ01012393    JAS57376.1    GEBQ01010341    JAT29636.1    NEDP02001549    OWF52993.1    MNPL01010405    OQR73140.1    PZQS01000001    PVD38507.1    GECU01020595    JAS87111.1    GEZM01051111    GEZM01051110    GEZM01051109    GEZM01051107    GEZM01051105    GEZM01051104    JAV75168.1    ABLF02026171    IACF01004451    LAB70044.1    GDIQ01014638    JAN80099.1    NOWV01000119    RDD39851.1    DS985242    EDV27355.1    AK340880    BAH71397.1    KK120523    KFM78438.1    GFDL01011960    JAV23085.1    EAAA01001620    DS231936    EDS27753.1    GADI01006823    JAA66985.1    GALX01005492    JAB62974.1    APGK01047787    BT127218    KB741089    KB632382    AEE62180.1    ENN73958.1    ERL94187.1    GEFM01003477    JAP72319.1    GBBL01001717    JAC25603.1    GBZX01001766    JAG90974.1    GDKW01002025    JAI54570.1    GAHY01002083    JAA75427.1    GFAC01003482    JAT95706.1    CAEY01000384    ABJB010713827    DS945857    EEC18634.1    GANO01001817    JAB58054.1    GEFH01004373    JAP64208.1    AZIM01000983    ETE68593.1    GBBM01002207    JAC33211.1    JO843859    AEO35476.1    GEDV01010656    JAP77901.1    JXUM01054927    KQ561844    KXJ77367.1    AGBW02008849    OWR52391.1    GAAZ01001789    JAA96154.1    GFPF01010608    MAA21754.1    GBBK01003430    JAC21052.1    AADN05000523    GL437203    EFN70844.1    GAPW01003592    JAC10006.1    KQ978344    KYM94822.1    AKHW03002956    KYO36242.1    CVRI01000047    CRK98422.1    JXUM01076094    KQ562924    KXJ74824.1    LSYS01008398    OPJ68987.1    KQ460044    KPJ18298.1    GDAY02001766    JAV49662.1    GBEX01002489    JAI12071.1    CH477586    EAT38617.1    MUZQ01000080    OWK59283.1    GFWV01009244    MAA33973.1    BC073573    AAH73573.1    JU175414    AFJ50938.1    GAEP01001135    JAB53686.1    LFJK02000008    POM45458.1    KQ459232    KPJ02534.1    MWRG01026311    PRD21448.1    AXCM01001158    AAPE02036788    AJWK01017046    ABQF01015865    CM004473    OCT82987.1    IACM01081533    LAB29017.1    AGTP01024032   

Proteomes

UP000005204    UP000218220    UP000037510    UP000085678    UP000000305    UP000245037    + More
UP000030746    UP000001554    UP000007266    UP000235965    UP000242188    UP000007875    UP000192223    UP000192247    UP000245119    UP000007819    UP000253843    UP000009022    UP000054359    UP000008144    UP000002320    UP000019118    UP000030742    UP000001646    UP000015104    UP000001555    UP000005226    UP000002280    UP000069940    UP000249989    UP000192221    UP000007151    UP000000539    UP000000311    UP000078542    UP000050525    UP000183832    UP000190648    UP000053240    UP000008820    UP000050792    UP000197619    UP000237256    UP000053268    UP000075883    UP000001074    UP000092461    UP000286641    UP000248482    UP000007754    UP000186698    UP000005215   

PRIDE

H9J845   

Pfam

PF03332   PMM

Interpro

IPR006379   HAD-SF_hydro_IIB        + More
IPR023214   HAD_sf       
IPR005002   PMM       
IPR036412   HAD-like_sf       

SUPFAM

SSF56784   SSF56784       

Gene 3D

3.40.50.1000    

CDD

cd02585  HAD_PMM

ProteinModelPortal

H9J845   A0A2W1BB19   A0A2A4JJZ2   A0A0L7LSL4   S4PMU4   I4DK74   + More
A0A2H1WVB5   A0A2I9LPG3   A0A1S3HCV3   A0A1S3KEL4   E9HCF1   A0A1B6DIM5   A0A0P4WB28   A0A2P8YKY2   V4BAW4   C3YWF0   D6WXJ2   A0A0P6BS41   A0A0P5R453   A0A2J7RAT9   A0A2J7RAU5   A0A0T6AZ43   A0A1B6G4M1   A0A1B6M126   A0A210QWA3   H2YEQ1   A0A1W4WZA5   A0A1V9XHX8   A0A2T7PYN3   A0A1B6IJL6   A0A1Y1LQR5   J9JYE1   A0A2P2I7N5   A0A0P6HUS4   A0A369RZY6   B3RMY2   C4WU27   A0A087UM49   A0A1Q3F690   F6SS61   A0A1W2WPB5   B0WHH5   A0A0K8R750   V5GG89   J3JVF0   G1KD11   A0A131XZ82   A0A023FY01   A0A0C9S225   A0A0P4VUS9   R4FJZ3   A0A1E1X9L8   T1KR88   B7QIG2   H2THT1   U5EKG9   A0A131XDM1   V8P3L0   A0A023GGU3   H9H6Z7   G3MPQ8   A0A131YIZ8   A0A182GCZ4   A0A1W4UVF1   A0A212FF79   T1D9U4   A0A224Z5T5   A0A023FHX0   A0A1D5PQW2   E2A6X8   H2RJ98   A0A023ELB7   A0A195C1U8   A0A151NHF5   A0A1J1IHA7   A0A182GNB4   A0A1V4JB57   A0A0N0PDS2   A0A1W7REV7   A0A0F7Z640   Q0IEM8   A0A183QQP1   A0A218UZV2   A0A293LZ40   Q6GNE0   J3S998   U3FWE0   A0A2P4W7H3   A0A194QAS7   A0A2P6K547   A0A182LXJ3   G1NY02   A0A1B0CL90   A0A3Q7RBJ5   A0A2Y9KEQ3   H0ZHY9   A0A1L8GGM9   A0A2D4M6K7   A0A287D5V8   A0A1S4FMN1  

PDB

6CFS     E-value=1.85521e-77,     Score=733

KEGG

101737280    K17497 phosphomannomutase [EC:5.4.2.8] | (RefSeq) phosphomannomutase 1

PATHWAY

00051    Fructose and mannose metabolism - Bombyx mori (domestic silkworm)
00520    Amino sugar and nucleotide sugar metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0009298   GO:0005737   GO:0004615   GO:0045047   GO:0005829   GO:0006013   GO:0006487   GO:0016787   GO:0043025   GO:1990830   GO:0008270   GO:0005488   GO:0005634   GO:0004672   GO:0030677   GO:0016155   GO:0003824  

PANTHER

PTHR10466  

Subcellular location

Cytoplasm  

Length:

250

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00334

Exp number, first 60 AAs:

0

Total prob of N-in:

0.08088

outside

1  -  250

 

 

Pi

132.27773

Theta

175.614761

Tajima's D

-0.624535

CLR

160.040095

CSRT

0.214239288035598

Interpretation

Uncertain