Gene

KWMTBOMO10040  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005528

Annotation

methylglutaconyl-CoA_hydratase_[Agrotis_segetum]

Location

Bomo_Chr17(+):794060-795326      View in EpiBrowser

Full name

Enoyl-CoA hydratase domain-containing protein 2, mitochondrial      

Location in the cell

Mitochondrial   Reliability : 2.018

CDS

ATGTTATTAAGTAAATTAAAATTGAGATCCTTCATTGTTAGAGTTGTAAATACCCGAAATCTAGCCACAAAGATACAACAACTGAACGAAAATGTGAATCCTGTTGTATTTGAGAAACTTACTGGGGTAGATAAGGGTATCGCATTATGCGGTCTCAACAGCCCTAAAGACAGGAACGCACTCGGATTTACCCTCATAGATGCGATGCGCGAGGTCAACCAGATCATTCGAGAAGATACCAAACTGTCTGTTGTTATCTTTCATAGTATGGTTCCGGGAATTTTCTGCGCTGGAGCTAACCTAAAAGAACGCTTAAAAATGTCCGATGAAGAGGTAGCCAAATTCGTTCGAGGGCTTAGAGAAACTTTTATTGAAATCGAAGACTTGCCCATGCCAACCATAGCTGCTGTGGAAGGAGTGGCTGTTGGTGGAGGGTTGGAATTAGCCTTGGCATGTGACATCAGGATAGCAGCAGATACTGCTAAACTAGGTCTTGTCGAGACTGGTAGAGGTCTTATTCCCGGTGCTGGAGGTACCCAGAGACTACCAAGAACTATTCAGCTACCAATTGCTAAAGAGTTGATATTTACATCAAGAATTGTTAGTGGAAAGGAAGCTAAAGCATTAGGCATAGTGAATCATGTGGTCGCACAAGACACTGCAAACAAAGCAGCCTTTGAGAAGGCCTTGAGCATTGCACGAGAAATCATCCCGAATGCCCCCATAGCCCTCCGTTGTGCAAAACAAGCTATCAGTGAAGGCATACAGCTGAGTATCAAGGATGGTTATGAGATAGAACAGAAATGCTACGAAATAAATATTCCAACTAAAGACAGACAGGAAGGCATGATTTCATTTATGGAAAAAAGAAAACCTGTTTATGAGGGACATTAG

Protein

MLLSKLKLRSFIVRVVNTRNLATKIQQLNENVNPVVFEKLTGVDKGIALCGLNSPKDRNALGFTLIDAMREVNQIIREDTKLSVVIFHSMVPGIFCAGANLKERLKMSDEEVAKFVRGLRETFIEIEDLPMPTIAAVEGVAVGGGLELALACDIRIAADTAKLGLVETGRGLIPGAGGTQRLPRTIQLPIAKELIFTSRIVSGKEAKALGIVNHVVAQDTANKAAFEKALSIAREIIPNAPIALRCAKQAISEGIQLSIKDGYEIEQKCYEINIPTKDRQEGMISFMEKRKPVYEGH

Similarity

Belongs to the enoyl-CoA hydratase/isomerase family.

Keywords

Acetylation   Alternative splicing   Complete proteome   Fatty acid metabolism   Lipid metabolism   Lyase   Mitochondrion   Reference proteome   Transit peptide  

Feature

chain  Enoyl-CoA hydratase domain-containing protein 2, mitochondrial
splice variant  In isoform 3.

Uniprot

H9J7N6   A0A2W1BDU2   A0A2H1WVB4   A0A2A4JK17   A0A068FRG3   A0A0N1IG39   + More
A0A194QC21   A0A212FF89   A0A0L7LS28   A0A3B0JXX1   A0A1A9WQK7   Q293E8   A0A1A9V7K5   A0A1I8QAE9   D3TMQ1   A0A1B0BED9   A0A1I8MGD0   A0A1A9Y995   A0A0A1WDA8   A0A0K8TMJ8   A0A0K8VQX0   A0A034VHU1   W8BT04   B4LP83   A0A1W4VPT6   B4KSP9   A0A182MUN3   B4MRY7   A1Z934   B4P506   B3MCU5   B4QDE9   A0A154P623   A0A088A241   A0A2A3E121   V9IJN7   B4JVM4   A0A151K0K2   B3NRX2   F4W715   A0A0B4J2T1   A0A232F961   A0A0N0U4J9   A0A195C3R8   A0A195AXN7   A0A158NM99   Q6DC25   A0A2D0SRC8   F1RDX1   A0A151X822   A0A0M4EWD6   A0A182QA34   A0A182KB30   A0A182FBY1   A0A0L7R4P2   A0A182JN03   A0A182LH73   A0A1S4H6F3   W5JDL7   A0A182TSI0   A0A2M4BV91   A0A2M4BUV0   A0A093QF19   A0A084VHY8   A0A3B4CQ36   A0A182Y722   A0A182V9B6   A0A182SH58   A0A3B3QCT0   R4WJY7   A0A218VEC6   A0A2C9GRT1   A0A2D0Q454   A0A0L0CS03   A0A3B5APY0   M4ANX5   A0A099Z015   A0A2M4AU08   A0A2M3ZAK0   A0A0B6Y9E6   A0A3P9NA04   A0A151M4H3   A0A1V4JY92   W5MNK4   A0A3P8YLY9   Q3TLP5   H2THP1   A0A3Q1EFY0   A0A0J7KTU4   A0A3L8SPZ4   A0A3Q3AI09   F1NSS6   A0A2R7WRU6   A0A2I4BS85   A0A3Q3J982   A0A182S090   A0A3Q1I191   A0A026WGH0   A0A3Q1G057   A0A146QKP3  

Pubmed

19121390    28756777    26385554    26354079    22118469    26227816    + More
15632085    17994087    20353571    25315136    25830018    26369729    25348373    24495485    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    22936249    21719571    20075255    28648823    21347285    23594743    20966253    12364791    20920257    23761445    24438588    25244985    29240929    23691247    26108605    23542700    22293439    25069045    16141072    19468303    15489334    21183079    23806337    23576753    21551351    30282656    15592404    24508170    30249741   

EMBL

BABH01020426    KZ150179    PZC72531.1    ODYU01011325    SOQ57003.1    NWSH01001312    + More
PCG71742.1    KJ622095    AID66685.1    KQ460044    KPJ18299.1    KQ459232    KPJ02535.1    AGBW02008849    OWR52390.1    JTDY01000229    KOB78184.1    OUUW01000001    SPP75938.1    CM000071    EAL24663.2    CCAG010005873    EZ422703    ADD18979.1    JXJN01012868    GBXI01017450    JAC96841.1    GDAI01002227    JAI15376.1    GDHF01011033    JAI41281.1    GAKP01016081    JAC42871.1    GAMC01002100    JAC04456.1    CH940648    EDW60192.2    CH933808    EDW10548.1    AXCM01001158    CH963850    EDW74876.1    AE013599    BT031029    AAF58477.2    ABV82411.1    CM000158    EDW90727.1    CH902619    EDV37347.1    CM000362    CM002911    EDX06814.1    KMY93296.1    KQ434823    KZC07307.1    KZ288467    PBC25415.1    JR049120    AEY60867.1    CH916375    EDV98492.1    KQ981253    KYN44174.1    CH954179    EDV56274.1    GL887802    EGI70005.1    AAZX01007340    NNAY01000614    OXU27391.1    KQ435812    KOX72771.1    KQ978344    KYM94823.1    KQ976716    KYM76807.1    ADTU01002232    BC078266    AAH78266.1    CR848004    KQ982431    KYQ56474.1    CP012524    ALC42095.1    AXCN02001118    KQ414657    KOC65835.1    AAAB01008816    ADMH02001689    ETN61423.1    GGFJ01007710    MBW56851.1    GGFJ01007709    MBW56850.1    KL671494    KFW82677.1    ATLV01013250    KE524847    KFB37582.1    AK417930    BAN21145.1    MUZQ01000002    OWK64444.1    APCN01004488    JRES01000091    KNC34204.1    KL886654    KGL74125.1    GGFK01010936    MBW44257.1    GGFM01004749    MBW25500.1    HACG01005210    CEK52075.1    AKHW03006631    KYO19371.1    LSYS01005497    OPJ77075.1    AHAT01002719    AHAT01002720    AHAT01002721    AHAT01002722    AHAT01002723    AK005030    AK153878    AK160482    AK166388    AK166965    AL844206    BX293563    BC025104    LBMM01003274    KMQ93721.1    QUSF01000010    RLW05969.1    AADN05000647    KK855346    PTY22091.1    KK107231    QOIP01000009    EZA55068.1    RLU18948.1    GCES01129614    GCES01055082    JAQ56708.1    JAR31241.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000037510    + More
UP000268350    UP000091820    UP000001819    UP000078200    UP000095300    UP000092444    UP000092460    UP000095301    UP000092443    UP000008792    UP000192221    UP000009192    UP000075883    UP000007798    UP000000803    UP000002282    UP000007801    UP000000304    UP000076502    UP000005203    UP000242457    UP000001070    UP000078541    UP000008711    UP000007755    UP000002358    UP000215335    UP000053105    UP000078542    UP000078540    UP000005205    UP000221080    UP000000437    UP000075809    UP000092553    UP000075886    UP000075881    UP000069272    UP000053825    UP000075880    UP000075882    UP000000673    UP000075902    UP000053258    UP000030765    UP000261440    UP000076408    UP000075903    UP000075901    UP000261540    UP000197619    UP000075840    UP000037069    UP000261400    UP000002852    UP000053641    UP000242638    UP000050525    UP000190648    UP000018468    UP000265140    UP000000589    UP000005226    UP000257200    UP000036403    UP000276834    UP000264800    UP000000539    UP000192220    UP000261600    UP000075900    UP000265040    UP000053097    UP000279307   

PRIDE

H9J7N6    A1Z934    Q3TLP5   

Pfam

PF00378   ECH_1        + More
PF04263   TPK_catalytic
PF04265   TPK_B1_binding
PF04573   SPC22

Interpro

IPR029045   ClpP/crotonase-like_dom_sf        + More
IPR001753   Enoyl-CoA_hydra/iso       
IPR014748   Enoyl-CoA_hydra_C       
IPR018376   Enoyl-CoA_hyd/isom_CS       
IPR006282   Thi_PPkinase       
IPR036759   TPK_catalytic_sf       
IPR036371   TPK_B1-bd_sf       
IPR007373   Thiamin_PyroPKinase_B1-bd       
IPR007371   TPK_catalytic       
IPR007653   SPC3       

SUPFAM

SSF52096   SSF52096        + More
SSF63999   SSF63999       
SSF63862   SSF63862       

Gene 3D

1.10.12.10     3.40.50.10240    

CDD

cd07995  TPK

ProteinModelPortal

H9J7N6   A0A2W1BDU2   A0A2H1WVB4   A0A2A4JK17   A0A068FRG3   A0A0N1IG39   + More
A0A194QC21   A0A212FF89   A0A0L7LS28   A0A3B0JXX1   A0A1A9WQK7   Q293E8   A0A1A9V7K5   A0A1I8QAE9   D3TMQ1   A0A1B0BED9   A0A1I8MGD0   A0A1A9Y995   A0A0A1WDA8   A0A0K8TMJ8   A0A0K8VQX0   A0A034VHU1   W8BT04   B4LP83   A0A1W4VPT6   B4KSP9   A0A182MUN3   B4MRY7   A1Z934   B4P506   B3MCU5   B4QDE9   A0A154P623   A0A088A241   A0A2A3E121   V9IJN7   B4JVM4   A0A151K0K2   B3NRX2   F4W715   A0A0B4J2T1   A0A232F961   A0A0N0U4J9   A0A195C3R8   A0A195AXN7   A0A158NM99   Q6DC25   A0A2D0SRC8   F1RDX1   A0A151X822   A0A0M4EWD6   A0A182QA34   A0A182KB30   A0A182FBY1   A0A0L7R4P2   A0A182JN03   A0A182LH73   A0A1S4H6F3   W5JDL7   A0A182TSI0   A0A2M4BV91   A0A2M4BUV0   A0A093QF19   A0A084VHY8   A0A3B4CQ36   A0A182Y722   A0A182V9B6   A0A182SH58   A0A3B3QCT0   R4WJY7   A0A218VEC6   A0A2C9GRT1   A0A2D0Q454   A0A0L0CS03   A0A3B5APY0   M4ANX5   A0A099Z015   A0A2M4AU08   A0A2M3ZAK0   A0A0B6Y9E6   A0A3P9NA04   A0A151M4H3   A0A1V4JY92   W5MNK4   A0A3P8YLY9   Q3TLP5   H2THP1   A0A3Q1EFY0   A0A0J7KTU4   A0A3L8SPZ4   A0A3Q3AI09   F1NSS6   A0A2R7WRU6   A0A2I4BS85   A0A3Q3J982   A0A182S090   A0A3Q1I191   A0A026WGH0   A0A3Q1G057   A0A146QKP3  

PDB

2ZQR     E-value=1.05619e-61,     Score=599

KEGG

101737137    K05607 methylglutaconyl-CoA hydratase [EC:4.2.1.18] | (RefSeq) enoyl-CoA hydratase domain-containing

PATHWAY

00280    Valine, leucine and isoleucine degradation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0003824   GO:0009631   GO:0016829   GO:0006635   GO:0005739   GO:0004300   GO:0009229   GO:0004788   GO:0006772   GO:0005524   GO:0030975   GO:0005787   GO:0008233   GO:0016021   GO:0006465   GO:0008152   GO:0016192   GO:0008270   GO:0005488   GO:0005634   GO:0004672   GO:0030677   GO:0016155  

Subcellular location

Mitochondrion  

Length:

297

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.44488

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02872

outside

1  -  297

 

 

Pi

167.003305

Theta

142.393223

Tajima's D

0.504978

CLR

83.465946

CSRT

0.517274136293185

Interpretation

Uncertain