Gene

KWMTBOMO10038

Pre Gene Modal

BGIBMGA005526

Annotation

putative_light_protein?_partial_[Operophtera_brumata]

Location

Bomo_Chr17(+):749230-753245      View in EpiBrowser

Full name

Vacuolar protein sorting-associated protein 41 homolog      

Location in the cell

Cytoplasmic   Reliability : 2.348

CDS

ATGGCTGTTAATATTGAGAGCTGCGAAAGCTTGCCTCCCGATGAGGAGCCGAAGCTAAAATACGATAGAATGGAAAATGATTTATTGAATATTTTACTGAAAGACGCTGTCAGTTGTATTTGTGTTCACACCAAATTCATCTGTATCGGAACACGTTGGGGTGTGATACACCTGCTAGATCACGAAGGTAACATAGTTGCTATATCCCAGGACGGGAAGACTGAATTCCAGGCTCATACTATCGCTGTCAACCAAATATCTGTAGACCAAAATGGGGATTACATAGCGAGTTGTTCAGACGATGGTAAAGTTGTCGTATATGGATTGTACAGTAATGATAACACGCACAACCTAAATTTAGGCAGGGCAGTGAAATCAGTTGCATTGGATCCTTGCTACTTCAAGTCAGGTTCAGGAAGAAGATTTCTTACAGGTGATCACAGATTGACACTATATGAAAAATCATTCCTTAATCGAATACGAACTACAGTATTACATGAATGCAAGGGAAACGTACAAGCCATGTCCTGGCAAGACAGGTTTGTAGCATGGGCAAGTGAAGTTGGGGTCCGTGTTTATGACCTAGTTGCTAAATGCTCTCTAGGTCTCATCCAATGGGAAAAGAACCTAAATAGATCTATTGAAGACTACCGCTGCAATCTTCTCTGGTCTGCTCCTAAGACTCTAATGATCGGCTGGGTTGATACCATCAGGATATGTGTCATTAGAAAGCGAAGTCAAATTGAATTACAGACTCGTGATGTCACAGAATACCTCGTGGATCCAATATATACCTACCAAATAGATTATTTTATAGGAGGTCTGGGCCCTTTGGACGATCTATTAGTTTTATTAGCCGTTCCAAAAGAATGCGATCCTAAAACCGGAAAGTCGCAAATGCCCGTTTTAATAGTGGCGAATTATAAAGGCTGCGAATTCTGCGAGATATCTTGGGAGACTTTAGACATAAGGGGCTACCAAGAATATAACTGTAATGATTACCATTTAGATATGCTTATAGAAGAAAACAGATTTTTTATTGTTTCCCCCAAAGACATTATCATAGCGAGCCCTTACGACATTGACGATAGAGTCACTTGGTTGACCCAACATAGAAGGTTCGAAAAAGCTATTGCCGTGTTGGAAGAGGTCGGTGGTAAAACTTCTAAGCACTCCGTGATGACGGTGGGCGTACAGTATTTAGATCACTTGCTCTCTGAACATCTTTATCAAGAGGCTGCCATTCTCTGTGCCAGAATATTTAAAAACGATAAAGTTTTATTAGAAAATCAAATATTAAAGTTTGCCGGCGTCAAACAACTTAGAACTATAAGTCCCTACGTGCCGAAGACGCCTGAACAAGCTTTAAGTCCTTACATATACGAAATAATACTTTTCGAATACCTCGAAGTGGATTCGCGAGGATTTTTAAAAATAATTAAAGAATGGAATCCAACTCTATACAAAACGAGCGTCGTTATAAACAAAGTAATCGAACATTTGTTAAACACCGAAGTTGACACGAACGTGTATCTGGAAACCTTAGCTTTACTTTACTGCCACCAAAAGCAATACGATAAAGCGCTGACAACATTCTTAACATTGCAACACAAGGATGTATTCAAATTGATAACAGACCACGAAATCTACAACATCATACAGGACAAGATACTCGATCTAATGACGCTAGACTGCGACCAGGCTATATCGATACTCTTGAATAACACAAAAATCCCTGTTGAGGTCGTCGAACAACAACTGGCAAATCACGAAGAATATTTGTATAAGTACTTAGACGCGTACAGCAAGATGGAACCGAACGGTCGATACCATGGAAAACTGGTTCGTCTATACGCCAAATACAACAAAGAAAAACTGTTGCCTTTCTTAAGATGCAGCGATAATTATCCCATACAGGAAGCTTTAGACGTGTGTCAGGCCAACAATTTTTTCCCAGAAATGGTTTTTCTACTCGCGAGAATCGGCAACACCAAGGAGGCATTGCAGATAATTATCGAACAGTTAAACGACATAAACCAAGCCATAACTTTCTGTCAAGAACAAAACGATATGGAACTTTGGATAGATCTGATACAGCAGACGGTCGACAAGCCGGAATATGTCACTTTACTTCTGAAAAGGATAGGGAACTACGTGGACCCGAGGATGTTGATACAGAACATCAAACCGGGCTGCGAAATAAAAGACCTCAAAGAGTGCTTAGCCAAAATGATGTGCGACTATCATCTCCAGCTATCAGTGCAGGAGGCCTGTAAAGTCATTACGCTGAGGAACTATTTTGATTTGCATGAAAAGCAAGTGATGGCTCAACAACGAGGCATATCGGTGACCGACGACTTCCTCTGCTGCGTTTGTCACGGGCGGATCATAATAAGGGACATGTCGAATGCTTCTGACCTTCTAGTTTACAATTGCAGACATTCCTTCCACGCCGGCTGCCTCCCGGAAGGCGACCAGTGTGCTGTTTGTAATGCGGTCAGAATGTGA

Protein

MAVNIESCESLPPDEEPKLKYDRMENDLLNILLKDAVSCICVHTKFICIGTRWGVIHLLDHEGNIVAISQDGKTEFQAHTIAVNQISVDQNGDYIASCSDDGKVVVYGLYSNDNTHNLNLGRAVKSVALDPCYFKSGSGRRFLTGDHRLTLYEKSFLNRIRTTVLHECKGNVQAMSWQDRFVAWASEVGVRVYDLVAKCSLGLIQWEKNLNRSIEDYRCNLLWSAPKTLMIGWVDTIRICVIRKRSQIELQTRDVTEYLVDPIYTYQIDYFIGGLGPLDDLLVLLAVPKECDPKTGKSQMPVLIVANYKGCEFCEISWETLDIRGYQEYNCNDYHLDMLIEENRFFIVSPKDIIIASPYDIDDRVTWLTQHRRFEKAIAVLEEVGGKTSKHSVMTVGVQYLDHLLSEHLYQEAAILCARIFKNDKVLLENQILKFAGVKQLRTISPYVPKTPEQALSPYIYEIILFEYLEVDSRGFLKIIKEWNPTLYKTSVVINKVIEHLLNTEVDTNVYLETLALLYCHQKQYDKALTTFLTLQHKDVFKLITDHEIYNIIQDKILDLMTLDCDQAISILLNNTKIPVEVVEQQLANHEEYLYKYLDAYSKMEPNGRYHGKLVRLYAKYNKEKLLPFLRCSDNYPIQEALDVCQANNFFPEMVFLLARIGNTKEALQIIIEQLNDINQAITFCQEQNDMELWIDLIQQTVDKPEYVTLLLKRIGNYVDPRMLIQNIKPGCEIKDLKECLAKMMCDYHLQLSVQEACKVITLRNYFDLHEKQVMAQQRGISVTDDFLCCVCHGRIIIRDMSNASDLLVYNCRHSFHAGCLPEGDQCAVCNAVRM

Description

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.

Similarity

Belongs to the VPS41 family.
Belongs to the FBPase class 1 family.

Uniprot

H9J7N4   A0A2A4JGH8   A0A2W1BI69   A0A2H1WTJ1   A0A0L7LRU4   A0A212FF77   + More
A0A194QAH7   A0A0N1IPT3   A0A3S2PEC0   A0A067QY06   A0A1Y1M1I5   D2A5A3   A0A088AMB9   A0A2A3E7V0   E2BHH5   A0A232EXD2   E2ABX3   A0A0M9AA07   A0A1L8DVT6   A0A158NL78   A0A195BY12   A0A195BFV3   A0A1Q3FE53   A0A151JSM3   A0A151WHF1   A0A195F0P5   A0A0C9PHG4   B0WUB3   A0A084VMX0   W5JRN4   A0A2M4CY22   A0A2M4AD66   A0A2M4ACI9   A0A0N8ERW9   A0A1I8JSK6   A0A182Y9S3   A0A2J7Q9R1   A0A182IX16   A0A182QF86   A0A182M9Z9   A0A182WH67   A0A182PFR5   A0A182R6J0   A0A182KAX8   A0A182VF10   A0A1I8JVZ5   A0A1Y9GKU3   Q7PVV4   E9J123   U4UYK7   N6TLU3   A0A1S4H0D6   A0A3L8DTA4   F4X642   A0A2M4ADT6   A0A310SC13   A0A182NF47   A0A336KCB0   A0A1B6BZ97   A0A1B6D753   A0A1B6CQD6   A0A1B6C2S4   A0A182UJC0   A0A0P6I3T2   A0A0P5D2G6   A0A0P5BQ39   A0A0P5XIT6   A0A162CAG7   A0A0N8BYH2   A0A0P6FXI0   A0A0L7RCU8   E9FYK6   J9K6C7   A0A0P4Y1X2   A0A0P6F0Y2   A0A154P1E0   A0A2H8TUJ9   A0A0K8TMJ4   A0A0N8C5S3   A0A0P5D0K8   A0A0N7ZKY4   A0A224X744   A0A069DWL6   E0VK08   A0A0P5PYV0   A0A023F2M8   A0A0P4W4B1   A0A0K8VL42   A0A1A9WES6   A0A1B0FA38   B4KFT8   A0A1I8M5E1   A0A1I8PEM5   A0A0A1WFZ4   A0A0P5DRT4   A0A0P5VB79   A0A0A9XUE9   A0A0L0C426   A0A0P4YYI3   A0A3B0JYN3  

Pubmed

19121390    28756777    26227816    22118469    26354079    24845553    + More
28004739    18362917    19820115    20798317    28648823    21347285    24438588    20920257    23761445    26999592    25244985    12364791    21282665    23537049    30249741    21719571    21292972    26369729    26334808    20566863    25474469    27129103    17994087    25315136    25830018    25401762    26823975    26108605   

EMBL

BABH01020434    NWSH01001549    PCG70886.1    KZ150179    PZC72526.1    ODYU01010946    + More
SOQ56371.1    JTDY01000229    KOB78185.1    AGBW02008849    OWR52386.1    KQ459232    KPJ02538.1    KQ460044    KPJ18302.1    RSAL01000075    RVE48905.1    KK853123    KDR11061.1    GEZM01043149    JAV79271.1    KQ971345    EFA05104.1    KZ288340    PBC27770.1    GL448301    EFN84828.1    NNAY01001745    OXU23046.1    GL438386    EFN69068.1    KQ435711    KOX79536.1    GFDF01003544    JAV10540.1    ADTU01019279    ADTU01019280    ADTU01019281    ADTU01019282    KQ978501    KYM93549.1    KQ976488    KYM83490.1    GFDL01009211    JAV25834.1    KQ978530    KYN30284.1    KQ983120    KYQ47238.1    KQ981866    KYN34048.1    GBYB01000263    JAG70030.1    DS232103    EDS34885.1    ATLV01014632    KE524975    KFB39314.1    ADMH02000666    ETN65394.1    GGFL01006054    MBW70232.1    GGFK01005351    MBW38672.1    GGFK01005176    MBW38497.1    GDUN01001098    JAN94821.1    NEVH01016344    PNF25314.1    AXCN02000829    AXCM01001716    APCN01003788    AAAB01008984    EAA14980.4    GL767540    EFZ13482.1    KB632429    ERL95476.1    APGK01019082    KB740092    ENN81419.1    QOIP01000004    RLU23670.1    GL888769    EGI58075.1    GGFK01005633    MBW38954.1    KQ761619    OAD57320.1    UFQS01000259    UFQT01000259    SSX02151.1    SSX22528.1    GEDC01030712    JAS06586.1    GEDC01015781    JAS21517.1    GEDC01021677    JAS15621.1    GEDC01029487    JAS07811.1    GDIQ01010009    JAN84728.1    GDIP01161982    JAJ61420.1    GDIP01186271    JAJ37131.1    GDIP01071491    JAM32224.1    LRGB01001151    KZS13472.1    GDIQ01132483    JAL19243.1    GDIQ01052703    JAN42034.1    KQ414615    KOC68581.1    GL732527    EFX87545.1    ABLF02040091    ABLF02040104    ABLF02040105    ABLF02040112    GDIP01233711    JAI89690.1    GDIQ01054544    JAN40193.1    KQ434796    KZC05745.1    GFXV01005043    MBW16848.1    GDAI01002232    JAI15371.1    GDIQ01112075    JAL39651.1    GDIP01164538    JAJ58864.1    GDIP01235265    JAI88136.1    GFTR01008149    JAW08277.1    GBGD01000456    JAC88433.1    DS235235    EEB13714.1    GDIQ01123626    JAL28100.1    GBBI01003331    JAC15381.1    GDKW01000417    JAI56178.1    GDHF01013059    JAI39255.1    CCAG010005354    CH933807    EDW12064.1    GBXI01016338    JAC97953.1    GDIP01151568    JAJ71834.1    GDIP01102726    JAM00989.1    GBHO01021076    GBHO01021074    GBRD01015152    GDHC01012615    JAG22528.1    JAG22530.1    JAG50674.1    JAQ06014.1    JRES01000940    KNC26991.1    GDIP01220763    JAJ02639.1    OUUW01000010    SPP85542.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000007151    UP000053268    UP000053240    + More
UP000283053    UP000027135    UP000007266    UP000005203    UP000242457    UP000008237    UP000215335    UP000000311    UP000053105    UP000005205    UP000078542    UP000078540    UP000078492    UP000075809    UP000078541    UP000002320    UP000030765    UP000000673    UP000069272    UP000076408    UP000235965    UP000075880    UP000075886    UP000075883    UP000075920    UP000075885    UP000075900    UP000075881    UP000075903    UP000076407    UP000075840    UP000007062    UP000030742    UP000019118    UP000279307    UP000007755    UP000075884    UP000075902    UP000076858    UP000053825    UP000000305    UP000007819    UP000076502    UP000009046    UP000091820    UP000092444    UP000009192    UP000095301    UP000095300    UP000037069    UP000268350   

PRIDE

H9J7N4   

Pfam

PF00637   Clathrin        + More
PF14538   Raptor_N
PF10367   Vps39_2
PF00316   FBPase

Interpro

IPR036322   WD40_repeat_dom_sf        + More
IPR001841   Znf_RING       
IPR011990   TPR-like_helical_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR001680   WD40_repeat       
IPR016024   ARM-type_fold       
IPR017986   WD40_repeat_dom       
IPR000547   Clathrin_H-chain/VPS_repeat       
IPR029347   Raptor_N       
IPR004083   Raptor       
IPR011989   ARM-like       
IPR016902   VPS41       
IPR019453   VPS39/TGF_beta_rcpt-assoc_2       
IPR033391   FBPase_N       
IPR000146   FBPase_class-1       
IPR020548   Fructose_bisphosphatase_AS       
IPR028343   FBPtase       

SUPFAM

SSF48371   SSF48371        + More
SSF50978   SSF50978       

Gene 3D

1.25.40.10     2.130.10.10     1.25.10.10    

CDD

cd00354  FBPase

ProteinModelPortal

H9J7N4   A0A2A4JGH8   A0A2W1BI69   A0A2H1WTJ1   A0A0L7LRU4   A0A212FF77   + More
A0A194QAH7   A0A0N1IPT3   A0A3S2PEC0   A0A067QY06   A0A1Y1M1I5   D2A5A3   A0A088AMB9   A0A2A3E7V0   E2BHH5   A0A232EXD2   E2ABX3   A0A0M9AA07   A0A1L8DVT6   A0A158NL78   A0A195BY12   A0A195BFV3   A0A1Q3FE53   A0A151JSM3   A0A151WHF1   A0A195F0P5   A0A0C9PHG4   B0WUB3   A0A084VMX0   W5JRN4   A0A2M4CY22   A0A2M4AD66   A0A2M4ACI9   A0A0N8ERW9   A0A1I8JSK6   A0A182Y9S3   A0A2J7Q9R1   A0A182IX16   A0A182QF86   A0A182M9Z9   A0A182WH67   A0A182PFR5   A0A182R6J0   A0A182KAX8   A0A182VF10   A0A1I8JVZ5   A0A1Y9GKU3   Q7PVV4   E9J123   U4UYK7   N6TLU3   A0A1S4H0D6   A0A3L8DTA4   F4X642   A0A2M4ADT6   A0A310SC13   A0A182NF47   A0A336KCB0   A0A1B6BZ97   A0A1B6D753   A0A1B6CQD6   A0A1B6C2S4   A0A182UJC0   A0A0P6I3T2   A0A0P5D2G6   A0A0P5BQ39   A0A0P5XIT6   A0A162CAG7   A0A0N8BYH2   A0A0P6FXI0   A0A0L7RCU8   E9FYK6   J9K6C7   A0A0P4Y1X2   A0A0P6F0Y2   A0A154P1E0   A0A2H8TUJ9   A0A0K8TMJ4   A0A0N8C5S3   A0A0P5D0K8   A0A0N7ZKY4   A0A224X744   A0A069DWL6   E0VK08   A0A0P5PYV0   A0A023F2M8   A0A0P4W4B1   A0A0K8VL42   A0A1A9WES6   A0A1B0FA38   B4KFT8   A0A1I8M5E1   A0A1I8PEM5   A0A0A1WFZ4   A0A0P5DRT4   A0A0P5VB79   A0A0A9XUE9   A0A0L0C426   A0A0P4YYI3   A0A3B0JYN3  

PDB

3IYV     E-value=0.00615271,     Score=97

KEGG

101737708    K20184 vacuolar protein sorting-associated protein 41 | (RefSeq) vacuolar protein sorting-associated

GO

GO:0005623   GO:0016192   GO:0006886   GO:0031931   GO:0031929   GO:0005770   GO:0030136   GO:0005769   GO:0005794   GO:0042144   GO:0005764   GO:0010008   GO:0035542   GO:0030897   GO:0005975   GO:0042132   GO:0016021   GO:0005840   GO:0005515   GO:0008270   GO:0005488   GO:0005634   GO:0004672   GO:0030677   GO:0016155   GO:0003824  

PANTHER

PTHR12848  

Subcellular location

Endosome membrane  
Late endosome  
Lysosome  
Golgi apparatus  
trans-Golgi network  
Early endosome  
Cytoplasmic vesicle  
Clathrin-coated vesicle  

Length:

835

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0618700000000002

Exp number, first 60 AAs:

0.05539

Total prob of N-in:

0.00286

outside

1  -  835

 

 

Pi

211.466919

Theta

170.994008

Tajima's D

0.36306

CLR

0

CSRT

0.47707614619269

Interpretation

Uncertain