Gene

KWMTBOMO10006  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005695

Annotation

triacylglycerol_lipase_[Bombyx_mori]

Location

Bomo_Chr17(+):125236-127023      View in EpiBrowser

Full name

Lipase      

Location in the cell

Extracellular   Reliability : 1.302 PlasmaMembrane   Reliability : 1.341

CDS

ATGAAGATGCACGTGTTCTTAGTTATTTTGGTGGCACTAGCGCGTGTCTCCGTCCAAGGGTTTGATTTGTTCGGAAGCTCGAGAAGCCTCGTCAATAACTTCGAAGACGCTCGTAACTACATCGAAACGCAAAAAGATAAGGTCATCGAAGAATGGTCCTCCTACATGGAAGACATAAAGCTGTCGAGCTCGTGGACGAACTTCTTAGAAGATAAAGAGAATCCGTCCTTGGAAGACCCCGACGTGGTGCTGAGCGTGCCCGCGATGATCACGCGGCGCGGCTACCGCTGTGAGACCCACTCGCTCATCTCCCAGGGATACGTGTTAAACATTCACAGGATACCGCAGGCTCGAAGCGGCGGCGACACTCCATCGAATACCGTGATACTTCAGCACGGCTTGTTTGCGAGCTCTGCCGACTGGGTCCTGAACGGGCCTGGAAAATCCTTAGCCTTCGTGTTGGCGGACGCCGGCTACGACGTCTGGATGCCAAACATAAGAGGTAACAGATATTCGAGGGAGCACACCACTTTAAAGAGCAGTTCGACTCAATATTGGAATTTCTCGTGGCACGAGGTCGCCCAGCACGACATCCCGGCCATCATAGACTATATCAGGGAGAGGAAGGGCTCGGACACAAAGATCGCGTACATGGGCCACTCGATGGGTTCCACGATGCTGTTCGCGATGCTGGCGCTGCGGCCGGAGTACAACGCGGTGCTGCGGGCGGGGCTCGCGCTCGGCCCCGTCGTCTACTTGTCTCATATCAAGTCGCCGGTCAAAACGCTAGCTCCGGTTGTCGCCAACGCGGCAAGAATGAACGTTATTAAAAACGGCGAATTTGTGCCGAAACAATCTGGCTTCGGACAAATGATGAGCGCGTGCAGCTCCGACGACGTGGACACGTACGTTTGTAAAAACGCAATATTCTTCATCTGCGGCACCGACGAGAAGCAGTTTAACAAGACGCTGCTGCCGGTGTTCCTGTCGCACCTCGGGACCGGCACGTCCATGAAGACCATCCTTCACTTCGCGCAGGAGATCGACGCCGCGGGACGCTTCCAGCAGTTCGACTACGGACCCACCAATAATATGAAAATATACAATTCAGAAACTCCACCAGAATACGATCTGCGCAAAATCACTCTTCCCATTTACCTGCTGTACTCAAGGAATGATTTATTGTCTAGCGAACAAGATGTTGATAAACTGTACCAAGATTTGGAAACCAGAACAGAAATCTACCTCGTACCGGACCCTGAGTTCAACCACGTGGATTACCTGATGGCGAACGACGCTCCGAGACTCTTGAACGACAAGGTGTTGCAGTTCTTGCTCGCAGCTTTTGCGGACCACCAAGGACCTGATCGTCACATGGGAACTCGCGAGTCAGTCCGCCAATACAAAGCATCACGTAAAGTGTTGAACACGTGA

Protein

MKMHVFLVILVALARVSVQGFDLFGSSRSLVNNFEDARNYIETQKDKVIEEWSSYMEDIKLSSSWTNFLEDKENPSLEDPDVVLSVPAMITRRGYRCETHSLISQGYVLNIHRIPQARSGGDTPSNTVILQHGLFASSADWVLNGPGKSLAFVLADAGYDVWMPNIRGNRYSREHTTLKSSSTQYWNFSWHEVAQHDIPAIIDYIRERKGSDTKIAYMGHSMGSTMLFAMLALRPEYNAVLRAGLALGPVVYLSHIKSPVKTLAPVVANAARMNVIKNGEFVPKQSGFGQMMSACSSDDVDTYVCKNAIFFICGTDEKQFNKTLLPVFLSHLGTGTSMKTILHFAQEIDAAGRFQQFDYGPTNNMKIYNSETPPEYDLRKITLPIYLLYSRNDLLSSEQDVDKLYQDLETRTEIYLVPDPEFNHVDYLMANDAPRLLNDKVLQFLLAAFADHQGPDRHMGTRESVRQYKASRKVLNT

Similarity

Belongs to the AB hydrolase superfamily. Lipase family.

Feature

chain  Lipase

Uniprot

H9J853   Q2F5V1   A0A0L7LD93   A0A2A4K5U1   S4NTM9   A0A2H1VNV1   + More
A0A0N0PE67   A0A212EIJ7   A0A194QAJ7   A0A212FL02   A0A0N1IA21   A0A2A4K7B0   H9J5B8   A0A2W1BV18   A0A0N0P9P4   A0A2H1VB04   A0A0S1MM91   A0A0L7LBN2   A0A0L7KSX2   A0A1J1HYK0   A0A182YB52   A0A182NS05   A0A182FP77   A0A182M714   Q7PXY2   A0A182L9V7   A0A182JYW0   W5JQ53   A0A182HLG5   A0A084VGT2   A0A182PGK0   A0A182WSL5   A0A182VB02   A0A182TMH4   B0WDK6   A0A1Q3G4Y3   A0A2M4DRZ0   K7J2Y1   A0A182HBR9   A0A182RZA1   A0A182VZF7   A0A182INM5   Q16MC7   A0A1L8DQ12   A0A1L8DPQ6   A0A182G6M0   A0A067RCF7   A0A232EG55   A0A026X0Q1   A0A2M4AWW8   A0A2M4AXH6   E2B370   A0A2J7QW32   D2A3G9   A0A151X254   X1WSL9   A0A1B2M4Y7   A0A1B0CJ10   D2A0X3   A0A195CME3   V5FYL0   A0A0P4WII3   A0A1D2MRG2   A0A1W4W6G4   A0A195FK23   A0A1Y1KBU1   A0A226E1Q5   A0A0T6BEX7   A0A088A7F6   A0A1B6HSA1   A0A1Y1MRZ1   A0A1B6G3S2   A0A1S3CXK0   A0A194R2Y3   A0A2J7PY44   A0A151IQS0   A0A158NIA5   A0A194PL00   A0A310SHS6   A0A2P8XRN9   A0A336LYU0   A0A1B6C389   A0A154PPL4   A0A195AVW7   A0A1B0CTU8   A0A158P269   A0A067R0F9   V5GWI8   E2AHE1   N6TR89   U4U932   A0A2J7QG30   A0A195E3Z0   J3JU88   A0A195F6E3   A0A084W6W2   A0A139WJB3   A0A067QXT1   A0A139WJS1  

Pubmed

19121390    22649392    23811219    26227816    23622113    26354079    + More
22118469    28756777    25244985    12364791    14747013    17210077    20966253    20920257    23761445    24438588    20075255    26483478    17510324    24845553    28648823    24508170    20798317    18362917    19820115    27289101    28004739    21347285    29403074    23537049    22516182   

EMBL

BABH01039868    KC702799    AB983536    AGN90922.1    BAQ20441.1    DQ311322    + More
ABD36266.1    JTDY01001689    KOB73151.1    NWSH01000095    PCG79625.1    GAIX01012151    JAA80409.1    ODYU01003406    SOQ42132.1    KQ460044    KPJ18326.1    AGBW02014621    OWR41323.1    KQ459232    KPJ02558.1    AGBW02008987    AGBW02007925    OWR51966.1    OWR54421.1    KQ460426    KPJ14773.1    NWSH01000071    PCG79959.1    BABH01037038    KC702800    AGN90923.1    KZ149927    PZC77505.1    KQ459256    KPJ02070.1    ODYU01001573    SOQ37981.1    KR821071    ALL42058.1    JTDY01001814    KOB72805.1    JTDY01006004    KOB66378.1    CVRI01000027    CRK92404.1    AXCM01002120    AAAB01008987    EAA00922.5    ADMH02000799    ETN65025.1    APCN01000897    ATLV01013084    KE524839    KFB37176.1    DS231898    EDS44615.1    GFDL01000188    JAV34857.1    GGFL01016104    MBW80282.1    JXUM01125660    JXUM01125661    JXUM01125662    KQ566971    KXJ69694.1    CH477866    EAT35492.1    GFDF01005649    JAV08435.1    GFDF01005648    JAV08436.1    JXUM01045142    KQ561427    KXJ78623.1    KK852794    KDR16428.1    NNAY01004862    OXU17327.1    KK107054    EZA61581.1    GGFK01011976    MBW45297.1    GGFK01011977    MBW45298.1    GL445305    EFN89852.1    NEVH01009768    PNF32784.1    KQ971338    EFA02315.1    KQ982580    KYQ54458.1    ABLF02039332    KX447604    AOA60271.1    AJWK01013948    EFA01616.1    KQ977622    KYN01254.1    GALX01005701    JAB62765.1    GDRN01044880    JAI66895.1    LJIJ01000666    ODM95481.1    KQ981523    KYN40354.1    GEZM01086956    JAV58943.1    LNIX01000009    OXA50396.1    LJIG01001091    KRT85849.1    GECU01030185    JAS77521.1    GEZM01023396    JAV88411.1    GECZ01012738    JAS57031.1    KQ460855    KPJ11879.1    NEVH01020850    PNF21255.1    KQ976755    KYN08590.1    ADTU01016204    ADTU01016205    KQ459601    KPI94007.1    KQ759878    OAD62255.1    PYGN01001466    PSN34671.1    UFQT01000235    SSX22181.1    GEDC01029317    GEDC01024313    GEDC01024096    GEDC01020251    JAS07981.1    JAS12985.1    JAS13202.1    JAS17047.1    KQ435012    KZC13809.1    KQ976731    KYM76202.1    AJWK01028000    ADTU01007002    KK852827    KDR15388.1    GALX01003858    JAB64608.1    GL439509    EFN67149.1    APGK01057867    APGK01057868    KB741282    ENN70836.1    KB632233    ERL90414.1    NEVH01014836    PNF27554.1    KQ979657    KYN19900.1    BT126801    AEE61763.1    KQ981763    KYN36038.1    ATLV01020990    KE525311    KFB45956.1    KYB28090.1    KK853131    KDR10945.1    KYB28091.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000053240    UP000007151    UP000053268    + More
UP000183832    UP000076408    UP000075884    UP000069272    UP000075883    UP000007062    UP000075882    UP000075881    UP000000673    UP000075840    UP000030765    UP000075885    UP000076407    UP000075903    UP000075902    UP000002320    UP000002358    UP000069940    UP000249989    UP000075900    UP000075920    UP000075880    UP000008820    UP000027135    UP000215335    UP000053097    UP000008237    UP000235965    UP000007266    UP000075809    UP000007819    UP000092461    UP000078542    UP000094527    UP000192223    UP000078541    UP000198287    UP000005203    UP000079169    UP000005205    UP000245037    UP000076502    UP000078540    UP000000311    UP000019118    UP000030742    UP000078492   

PRIDE

H9J853    Q2F5V1    H9J5B8   

Pfam

PF00561   Abhydrolase_1        + More
PF12146   Hydrolase_4
PF04083   Abhydro_lipase
PF01399   PCI

Interpro

IPR029058   AB_hydrolase        + More
IPR000073   AB_hydrolase_1       
IPR006693   AB_hydrolase_lipase       
IPR022742   Hydrolase_4       
IPR025483   Lipase_euk       
IPR011990   TPR-like_helical_dom_sf       
IPR019734   TPR_repeat       
IPR013026   TPR-contain_dom       
IPR000717   PCI_dom       
IPR036390   WH_DNA-bd_sf       

SUPFAM

SSF53474   SSF53474        + More
SSF48452   SSF48452       
SSF46785   SSF46785       

Gene 3D

3.40.50.1820     1.25.40.10    

ProteinModelPortal

H9J853   Q2F5V1   A0A0L7LD93   A0A2A4K5U1   S4NTM9   A0A2H1VNV1   + More
A0A0N0PE67   A0A212EIJ7   A0A194QAJ7   A0A212FL02   A0A0N1IA21   A0A2A4K7B0   H9J5B8   A0A2W1BV18   A0A0N0P9P4   A0A2H1VB04   A0A0S1MM91   A0A0L7LBN2   A0A0L7KSX2   A0A1J1HYK0   A0A182YB52   A0A182NS05   A0A182FP77   A0A182M714   Q7PXY2   A0A182L9V7   A0A182JYW0   W5JQ53   A0A182HLG5   A0A084VGT2   A0A182PGK0   A0A182WSL5   A0A182VB02   A0A182TMH4   B0WDK6   A0A1Q3G4Y3   A0A2M4DRZ0   K7J2Y1   A0A182HBR9   A0A182RZA1   A0A182VZF7   A0A182INM5   Q16MC7   A0A1L8DQ12   A0A1L8DPQ6   A0A182G6M0   A0A067RCF7   A0A232EG55   A0A026X0Q1   A0A2M4AWW8   A0A2M4AXH6   E2B370   A0A2J7QW32   D2A3G9   A0A151X254   X1WSL9   A0A1B2M4Y7   A0A1B0CJ10   D2A0X3   A0A195CME3   V5FYL0   A0A0P4WII3   A0A1D2MRG2   A0A1W4W6G4   A0A195FK23   A0A1Y1KBU1   A0A226E1Q5   A0A0T6BEX7   A0A088A7F6   A0A1B6HSA1   A0A1Y1MRZ1   A0A1B6G3S2   A0A1S3CXK0   A0A194R2Y3   A0A2J7PY44   A0A151IQS0   A0A158NIA5   A0A194PL00   A0A310SHS6   A0A2P8XRN9   A0A336LYU0   A0A1B6C389   A0A154PPL4   A0A195AVW7   A0A1B0CTU8   A0A158P269   A0A067R0F9   V5GWI8   E2AHE1   N6TR89   U4U932   A0A2J7QG30   A0A195E3Z0   J3JU88   A0A195F6E3   A0A084W6W2   A0A139WJB3   A0A067QXT1   A0A139WJS1  

PDB

1K8Q     E-value=3.13377e-65,     Score=631

KEGG

692912    no KO assigned | (RefSeq) lipase, pglip1; triacylglycerol lipase

GO

GO:0006629   GO:0016788   GO:0016042   GO:0044255   GO:0016298   GO:0005737   GO:0016021  

Subcellular location

Cytoplasm  

SignalP

Position:   1 - 20,         Likelihood:  0.996811

 

 

Length:

477

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.88571

Exp number, first 60 AAs:

1.65304

Total prob of N-in:

0.08791

outside

1  -  477

 

 

Pi

227.752361

Theta

214.461897

Tajima's D

-1.394996

CLR

0.270457

CSRT

0.0764461776911154

Interpretation

Uncertain