Gene

KWMTBOMO09985

Pre Gene Modal

BGIBMGA013215

Annotation

PREDICTED:_glucose_dehydrogenase_[FAD?_quinone]_[Bombyx_mori]

Location

Bomo_Chr16(-):14122533-14124491      View in EpiBrowser

Full name

Endoglucanase       + More
Glucose dehydrogenase [FAD, quinone]      

Location in the cell

Extracellular   Reliability : 2.61

CDS

ATGGCATCGTGCGACTGCCCGATGTCGCAGCCGGGTCCGACCCTGGCGGCGACCTGCGGCGGAGGGGCCTTCATGCTGTTCATGGGACTGCTGGAGGTGTTTCTGCGCAGCCAGTGCGACCTAGAGGACCCTTGTGGACGGACACAGTACCGTAGTGACATGGAGTCCGTGTACGACTTCATAGTGGTGGGGGGCGGGTCCGCGGGGTCCGTGGTGGCGGCGCGCCTCGCCGAGGTGCCACACTGGAGGGTGCTGCTGCTCGAAGCAGGTTTCGACGAGCCGACCGGTGCCCAGGTCCCATCAATGTTCCTGAACTTCATCGGCTCCAGCATCGACTGGGGCTACCACACTGAGCCCGAGCCCGCCGCCTGTCTCGCGGAAAAAGACAGGAAGTGCTATTGGCCCAGAGGAAAGGTCAGTGAATTTAGAATTAAGCAAATGCAGACATGTCACTGA

Protein

MASCDCPMSQPGPTLAATCGGGAFMLFMGLLEVFLRSQCDLEDPCGRTQYRSDMESVYDFIVVGGGSAGSVVAARLAEVPHWRVLLLEAGFDEPTGAQVPSMFLNFIGSSIDWGYHTEPEPAACLAEKDRKCYWPRGKVSEFRIKQMQTCH

Catalytic Activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
a quinone + D-glucose = a quinol + D-glucono-1,5-lactone

Cofactor

FAD

Similarity

Belongs to the GMC oxidoreductase family.
Belongs to the glycosyl hydrolase 9 (cellulase E) family.

Keywords

Complete proteome   FAD   Flavoprotein   Oxidoreductase   Reference proteome   Secreted   Selenocysteine   Signal  

Feature

chain  Endoglucanase

Uniprot

H9JUK2   A0A291P102   A0A291P0R7   A0A437BLQ3   A0A2H1WCL9   A0A0N1IP29   + More
A0A212F246   A0A194PXW0   A0A1B6C3H2   A0A2J7Q741   A0A2R7WDN2   N6U1S5   A0A139WGK8   A0A0A9ZH27   A0A067R3T3   A0A1S3D8R6   E0VK19   A0A2S2NJV8   A0A1I8PT77   A0A1I8N555   U3PT72   A0A2U8U0K3   P18173   Q8SXV0   A0A2S2QBR1   A0A0M4ECE1   T1PPA8   B4JFA8   J9JWH7   B4M4G1   Q94963   B4I4R7   T1HJQ6   A0A1A9WL86   A0A1A9Y074   A0A1B0FAV7   A0A1A9Z6K6   A0A1A9VQK6   O44106   P18172   A0A3B0JPT6   A0A336ME48   A0A0R3NJP9   W8B192   A0A336MPQ2   B4GMR4   D0QWK8   B4PRY5   A0A0A1XPD7   A0A182VWW9   A0A182VBZ4   A0A182UL69   A0A182XAV1   A0A182LES2   Q7QCC5   A0A182HSP9   A0A182NRL5   B3P2V7   A0A1B0DAQ7   A0A182RS69   A0A182MWU5   A0A1W4UYV9   A0A182J274   B4K6N7   A0A182R0I2   A0A023EV68   A0A084WSP2   B0WR76   Q178U1   A0A2M4CT25   A0A1B6EWY6   B4N874   A0A1W4VB63   B3LYF6   A0A0J7KW89   A0A1B6LIT7   A0A154PGL9   A0A0K8TXQ1   A0A087ZQ05   A0A2A3EJY8   A0A310SU95   A0A0C9PXZ5   A0A034WA73   A0A3L8E234   A0A1Q3FML5   A0A158NWQ4   A0A1W4XS38   A0A232F9V9   F4WQ30   A0A151I5L3   A0A026W0A3   A0A151JUB7   A0A195EDG1   E2BJ27   K7ITZ6   A0A1J1IAM9   A0A151IHR1   E2AQ44   A0A067QZE3  

EC Number

3.2.1.4
1.1.5.9

Pubmed

19121390    28986331    26354079    22118469    23537049    18362917    + More
19820115    25401762    26823975    24845553    20566863    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    2108306    3143620    2002763    17994087    8865667    9720289    15632085    15545653    23185243    24495485    19859648    17550304    25830018    20966253    12364791    14747013    17210077    24945155    24438588    17510324    25348373    30249741    21347285    28648823    21719571    24508170    20798317    20075255   

EMBL

BABH01022555    MF687604    ATJ44530.1    MF687548    ATJ44474.1    RSAL01000036    + More
RVE51239.1    ODYU01007445    SOQ50224.1    KQ460643    KPJ13316.1    AGBW02010783    OWR47815.1    KQ459595    KPI95985.1    GEDC01029508    JAS07790.1    NEVH01017447    PNF24406.1    KK854669    PTY17763.1    APGK01052880    KB741216    KB631897    ENN72507.1    ERL86928.1    KQ971344    KYB27092.1    GBHO01000088    GBHO01000087    GBRD01012593    GDHC01011845    GDHC01008977    JAG43516.1    JAG43517.1    JAG53231.1    JAQ06784.1    JAQ09652.1    KK852777    KDR16732.1    DS235237    EEB13725.1    GGMR01004840    MBY17459.1    BT150358    AGW52167.1    AE014297    AWM95310.1    M29298    X13582    AY084122    AAL89860.1    GGMS01005964    MBY75167.1    CP012526    ALC45304.1    KA649940    AFP64569.1    CH916369    EDV93389.1    ABLF02025721    CH940652    EDW59522.2    AH005098    U63324    AAB48020.1    CH480821    EDW55210.1    ACPB03021766    CCAG010022189    AF025811    AAB87896.1    M29299    CM000070    AY754494    OUUW01000008    SPP84125.1    UFQT01000848    SSX27631.1    KRT01170.1    KRT01171.1    GAMC01019535    GAMC01019534    JAB87021.1    UFQS01001751    UFQT01001751    SSX12203.1    SSX31655.1    CH479185    EDW38138.1    FJ821032    ACN94707.1    CM000160    EDW96385.1    GBXI01001864    JAD12428.1    AAAB01008859    EAA08043.3    APCN01000318    CH954181    EDV48129.1    AJVK01029227    AXCM01004736    CH933806    EDW14153.2    AXCN02000004    GAPW01000590    JAC13008.1    ATLV01026651    ATLV01026652    KE525416    KFB53236.1    DS232052    EDS33250.1    CH477359    EAT42711.1    GGFL01004328    MBW68506.1    GECZ01027399    JAS42370.1    CH964232    EDW81325.2    CH902617    EDV41819.2    LBMM01002471    KMQ94787.1    GEBQ01016380    JAT23597.1    KQ434893    KZC10614.1    GDHF01033243    GDHF01026224    JAI19071.1    JAI26090.1    KZ288227    PBC31794.1    KQ760241    OAD61292.1    GBYB01006377    GBYB01006378    GBYB01006379    GBYB01006380    GBYB01011403    JAG76144.1    JAG76145.1    JAG76146.1    JAG76147.1    JAG81170.1    GAKP01006471    JAC52481.1    QOIP01000001    RLU26592.1    GFDL01006281    JAV28764.1    ADTU01002979    NNAY01000667    OXU27097.1    GL888262    EGI63653.1    KQ976434    KYM87196.1    KK107522    EZA49345.1    KQ981799    KYN35699.1    KQ979074    KYN22852.1    GL448558    EFN84177.1    CVRI01000047    CRK97304.1    KQ977586    KYN01695.1    GL441691    EFN64444.1    KK853157    KDR10473.1   

Proteomes

UP000005204    UP000283053    UP000053240    UP000007151    UP000053268    UP000235965    + More
UP000019118    UP000030742    UP000007266    UP000027135    UP000079169    UP000009046    UP000095300    UP000095301    UP000000803    UP000092553    UP000001070    UP000007819    UP000008792    UP000001292    UP000015103    UP000091820    UP000092443    UP000092444    UP000092445    UP000078200    UP000001819    UP000268350    UP000008744    UP000002282    UP000075920    UP000075903    UP000075902    UP000076407    UP000075882    UP000007062    UP000075840    UP000075884    UP000008711    UP000092462    UP000075900    UP000075883    UP000192221    UP000075880    UP000009192    UP000075886    UP000030765    UP000002320    UP000008820    UP000007798    UP000007801    UP000036403    UP000076502    UP000005203    UP000242457    UP000279307    UP000005205    UP000192223    UP000215335    UP000007755    UP000078540    UP000053097    UP000078541    UP000078492    UP000008237    UP000002358    UP000183832    UP000078542    UP000000311   

PRIDE

H9JUK2    U3PT72    P18173    Q8SXV0    P18172   

Pfam

PF00732   GMC_oxred_N        + More
PF05199   GMC_oxred_C
PF00759   Glyco_hydro_9

Interpro

IPR007867   GMC_OxRtase_C        + More
IPR012132   GMC_OxRdtase       
IPR000172   GMC_OxRdtase_N       
IPR036188   FAD/NAD-bd_sf       
IPR008928   6-hairpin_glycosidase_sf       
IPR018221   Glyco_hydro_9_His_AS       
IPR012341   6hp_glycosidase-like_sf       
IPR033126   Glyco_hydro_9_Asp/Glu_AS       
IPR001701   Glyco_hydro_9       
IPR027424   Glucose_Oxidase_domain_2       

SUPFAM

SSF51905   SSF51905        + More
SSF48208   SSF48208       

Gene 3D

3.50.50.60     1.50.10.10     4.10.450.10    

ProteinModelPortal

H9JUK2   A0A291P102   A0A291P0R7   A0A437BLQ3   A0A2H1WCL9   A0A0N1IP29   + More
A0A212F246   A0A194PXW0   A0A1B6C3H2   A0A2J7Q741   A0A2R7WDN2   N6U1S5   A0A139WGK8   A0A0A9ZH27   A0A067R3T3   A0A1S3D8R6   E0VK19   A0A2S2NJV8   A0A1I8PT77   A0A1I8N555   U3PT72   A0A2U8U0K3   P18173   Q8SXV0   A0A2S2QBR1   A0A0M4ECE1   T1PPA8   B4JFA8   J9JWH7   B4M4G1   Q94963   B4I4R7   T1HJQ6   A0A1A9WL86   A0A1A9Y074   A0A1B0FAV7   A0A1A9Z6K6   A0A1A9VQK6   O44106   P18172   A0A3B0JPT6   A0A336ME48   A0A0R3NJP9   W8B192   A0A336MPQ2   B4GMR4   D0QWK8   B4PRY5   A0A0A1XPD7   A0A182VWW9   A0A182VBZ4   A0A182UL69   A0A182XAV1   A0A182LES2   Q7QCC5   A0A182HSP9   A0A182NRL5   B3P2V7   A0A1B0DAQ7   A0A182RS69   A0A182MWU5   A0A1W4UYV9   A0A182J274   B4K6N7   A0A182R0I2   A0A023EV68   A0A084WSP2   B0WR76   Q178U1   A0A2M4CT25   A0A1B6EWY6   B4N874   A0A1W4VB63   B3LYF6   A0A0J7KW89   A0A1B6LIT7   A0A154PGL9   A0A0K8TXQ1   A0A087ZQ05   A0A2A3EJY8   A0A310SU95   A0A0C9PXZ5   A0A034WA73   A0A3L8E234   A0A1Q3FML5   A0A158NWQ4   A0A1W4XS38   A0A232F9V9   F4WQ30   A0A151I5L3   A0A026W0A3   A0A151JUB7   A0A195EDG1   E2BJ27   K7ITZ6   A0A1J1IAM9   A0A151IHR1   E2AQ44   A0A067QZE3  

PDB

4HA6     E-value=0.000217579,     Score=100

KEGG

101736123    K00115 glucose 1-dehydrogenase (FAD, quinone) [EC:1.1.5.9] | (RefSeq) glucose dehydrogenase [FAD, qu

PATHWAY

00030    Pentose phosphate pathway - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0050660   GO:0016614   GO:0016021   GO:0030245   GO:0008810   GO:0004344   GO:0006006   GO:0008364   GO:0046693   GO:0005576   GO:0016491   GO:0006511   GO:0008233   GO:0005634   GO:0004672   GO:0030677   GO:0016155   GO:0003824   GO:0055114  

Subcellular location

Secreted  

Length:

151

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

31.87508

Exp number, first 60 AAs:

23.13737

Total prob of N-in:

0.21509

POSSIBLE N-term signal

sequence

outside

1  -  12

TMhelix

13  -  35

inside

36  -  151

 

 

Pi

156.136859

Theta

163.599526

Tajima's D

-0.181487

CLR

0.179126

CSRT

0.321833908304585

Interpretation

Uncertain