Gene

KWMTBOMO09952  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013237

Annotation

cytochrome_P450_[Bombyx_mori]

Location

Bomo_Chr16(-):12667502-12670792      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 2.554

CDS

ATGTCAGTGAGCGCATTAGTATTTTCCGCCTTCGTTTTATTAGTGACGTATATTTACTATTGGTCGACCCGGAAATTCGATTATTGGAAGCGAAAAAATGTGCCATACGCTAAACCTGTGCCGTTCTTTGGGAACTACATGCGATATATCACACTGCAGAGCTTCCTAGGAGATGTGATGCAGAAGCTGTGCCAGCAGTTCCCTGACAGACCGTACTTCGGATCGTTTTACGGTACGGAACCAGCCCTAGTCTTGCAGAATCCGGAGATCATCAAGCAAGTTTTTACTAAAGACTTCTATTACTTCAACAGCCGCGAAAACAGGGATTACAATCATAAGGAAGTATTCACACAGAACTTGTTCTTCGCCAATGGAGATAGATGGAAGGTAATACGTCAGAACCTAACCCCGCTGTTCTCATCGTCAAAGATGAAGAATATGTTTTACTTGGTGGAAAAATGCAACCATTCCCTTGAAGACATGCTGGACAAGGAAACCAAAGACTTGCAAAGTATTGAGATCCGGTCTGCTATGATAAGGTACACACTGGACTCTATCTGCTCTAGCGCCTTCGGTATCGAAACAAATACCTTAAGTGAGGGCGCAGAAAATAGTCCTTTTCCAAGCATGGGAAGCACCATATTTAGTTCTTCGATAACTCGAGGACTGAAATTGATTGGTCGTTCGATGTGGCCGGGCATATTCTATAAGCTTGGTCTCCGGTGCTTTCCAACGGAAATTGACGATTTCTTTGAGAGACTCCTGACTGAGGTGTTCGAGAACCGTGGCTACAAGCCGACGAACCGTAACGATTTCGTGGACTTAATCTTGAGTCTGAAACAAAACGATTACCTGACCGGAGATGGCTTGGTTCCCAAAAACGTGGACGCAAAGAAAGTGACGGTCAAGGTTGACGACGCCTTATTGATAGCGCAGTGCGTAGTCTTCTTTGGTGCAGGCTTCGAAACGTCAGCTACCACTCTCTCGGCAGCCCTATACGAGCTGGCCAAGAACCCAGAAGCCCAAAGGCGCGCTCAAGAGGAAGTTGACGAACTTTTGCTAAAACACAACAACAAGTTAAATTATGATTGTTTAGCAGAATTACCGTACTTGGAGGCATGTATGAACGAAGCGATGCGTCTGTACCCAGTATTTCCTAATATCACCCGCGAAACCGTTGCCGACTATACGTTTCCCGATGGCCTAAGGATAGATAAGGGTATGCGTGTGCATGTCCCGGTGTATGCTATCCACCGTAACCCCGACAACTTTCCTGACCCGGAAGAGTTTCGTCCTGAGAGACATTTAGGAGACGCCAAAAACGACATTAAGCAGTTCACGTTCTTCCCGTTCGGAGAAGGGCCCAGGATATGCATTGGTATGCGCTTCGGGAAAATGCAGACTATCGCTGGGCTGATTACCTGTTTGAAAAAGTTCAACTTCGAACTGGCGGACGGTATGCCGAGGACGCTAGCTTTTAGATCCACAACGTTGCTTACACAGCCGAGTACCGGATTATTCCTGAAGGCCACACCACGAGACGGATGGGAGCAACGTATTTTCGCACGTTAA

Protein

MSVSALVFSAFVLLVTYIYYWSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSEGAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKLGLRCFPTEIDDFFERLLTEVFENRGYKPTNRNDFVDLILSLKQNDYLTGDGLVPKNVDAKKVTVKVDDALLIAQCVVFFGAGFETSATTLSAALYELAKNPEAQRRAQEEVDELLLKHNNKLNYDCLAELPYLEACMNEAMRLYPVFPNITRETVADYTFPDGLRIDKGMRVHVPVYAIHRNPDNFPDPEEFRPERHLGDAKNDIKQFTFFPFGEGPRICIGMRFGKMQTIAGLITCLKKFNFELADGMPRTLAFRSTTLLTQPSTGLFLKATPRDGWEQRIFAR

Cofactor

heme

Similarity

Belongs to the cytochrome P450 family.

Uniprot

L0N766   L0N7C5   D6MLU9   B6VFR9   A9YXV8   A4GUB9   + More
A5JM34   A9QW13   A5HG34   H9JUM4   A3RIC0   L0N6H5   A0A172MF86   D5L0M6   A0A0L7KJY7   A0A248QEX7   A0A0L7LJH7   A0A2A4J698   A0A068EWQ5   Q2XSW1   A0A068EU72   A0A068EVK6   A0A068F0X2   A0A0L7LRY0   A0A068EVD2   A0A2A4J2E3   A0A068EVL0   Q7YZS2   A0A0K8TUL3   A0A068ETU4   H2CZF1   H2CZE9   A0A0L7KVL1   A0A068EU65   F4YCW0   A0A3S2LFF7   A0A0K0YD30   Q069I9   A0A2A4JAM9   A0A2A4JAK3   A0A068ETU8   A0A248QHF4   A0A2A4J7V4   B3VT94   A0A248QEF8   A0A068F1Z7   A0A2H1V0E7   A0A2H1WID4   A0A2A4J918   J7FKN2   A0A0C5C1I6   A0A0K8TUI1   A0A3S2P9Y7   C1LZ54   J7FJF2   H9JUM8   A4GUB8   A0A437B5H6   A0A1V0D9E0   A0A1V0D9D9   A0A0N1IP03   A0A1V0D9D6   J7FKN1   A0A068EWQ0   X5D9B5   A0A411E5Q0   A0A0A7DH57   A0A2H1V048   A0A0N1ID06   A0A286QUG7   D2JLK6   W5VY13   A9QW15   A0A3S2LW02   A5HKM1   A0A0C5CGV6   A0A2A4JWC6   A0A222NX20   A0A0K8TV92   A0A2W1BGY9   L0N6M3   C7U1L4   A0A068F0X7   A0A248QG18   A0A0A7DH10   H9JUM5   J7FJF3   A0A2H1VU17   A0A248QEH8   A0A0A7DGX3   A0A0A7DH65   A5HG33   H9JUM6   A0A411AG09   A0A0A7DG86   D5L0M5   A0A0A7DH14   A0A2H1VSH4   A0A2H1VSG7  

Pubmed

19121390    19909380    26227816    28881445    25315858    15606809    + More
26017144    17982444    22984814    26354079    24361403    19954531    28756777   

EMBL

AK343205    BAM73891.1    AK289291    AK343204    BAM73818.1    BAM73890.1    + More
GQ241737    ADD70250.1    FJ387169    ACJ10074.1    EU309477    ABY40426.1    EF432657    ABO21683.1    EF547545    ABQ42339.1    EU273875    ABX64438.1    EF528486    ABP99020.1    BABH01022694    EF415296    ABN71367.1    AK289290    BAM73817.1    KU145393    ANC96676.1    GU731531    ADE05581.1    JTDY01009617    KOB63214.1    KX443435    ASO98010.1    JTDY01000942    KOB75351.1    NWSH01002736    PCG67605.1    KM016744    AID54896.1    DQ256407    ABB69054.1    KM016742    AID54894.1    KM016736    AID54888.1    KM016738    AID54890.1    JTDY01000272    KOB77971.1    KJ671575    AID55427.1    NWSH01003425    PCG66327.1    KM016741    AID54893.1    AY295774    AAP83689.1    GCVX01000058    JAI18172.1    KM016735    AID54887.1    JN375491    AEY75585.1    JN375489    AEY75583.1    JTDY01005369    KOB67074.1    KM016737    AID54889.1    GU937509    ADW23116.1    RSAL01000158    RVE45547.1    KR095600    AKS48888.1    DQ986461    JN176574    ABI84381.1    AET11931.1    NWSH01002369    PCG68453.1    PCG68452.1    KM016740    AID54892.1    KX443432    ASO98007.1    PCG67604.1    EU807990    ACF17813.2    KX443430    ASO98005.1    KJ671576    AID55428.1    ODYU01000082    SOQ34236.1    ODYU01008863    SOQ52829.1    PCG68451.1    JX310082    AFP20593.1    KP001126    AJN91171.1    GCVX01000081    JAI18149.1    RVE45548.1    FN356971    CAX94849.1    JX310078    AFP20589.1    BABH01022705    EF432656    ABO21682.1    RVE45549.1    KY212044    ARA91608.1    KY212043    ARA91607.1    KQ460655    KPJ12961.1    KY212045    ARA91609.1    JX310077    AFP20588.1    KM016739    AID54891.1    KF701137    AHW57307.1    MH236461    QBA57466.1    KJ645906    AIJ00763.1    ODYU01000083    SOQ34238.1    KQ459388    KPJ01135.1    KX443431    ASO98006.1    GQ915322    ACZ97416.2    KF853191    AHH92929.1    EU273877    ABX64440.1    RVE45546.1    EF535809    ABQ08711.1    KP001127    AJN91172.1    NWSH01000502    PCG75998.1    KX844829    ASQ44127.1    GCVX01000049    JAI18181.1    KZ150141    PZC72944.1    AK343206    BAM73892.1    FN544262    CBB07053.1    KM016743    AID54895.1    KX443433    ASO98008.1    KJ645904    AIJ00761.1    JX310083    AFP20594.1    ODYU01004424    SOQ44278.1    KX443434    ASO98009.1    KJ645907    AIJ00764.1    KJ645905    AIJ00762.1    EF528485    ABP99019.1    BABH01022698    MH151918    QAX33066.1    KJ645908    AIJ00765.1    GU731530    ADE05580.1    KJ645909    AIJ00766.1    ODYU01004193    SOQ43795.1    ODYU01004192    SOQ43793.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000283053    UP000053240    UP000053268    + More

PRIDE

L0N766    L0N7C5    D6MLU9    B6VFR9    A4GUB9    A5JM34    + More
A5HG34    H9JUM4    A3RIC0    L0N6H5    H9JUM8    A4GUB8    A5HKM1    L0N6M3    H9JUM5    A5HG33    H9JUM6   

Pfam

PF00067   p450        + More
PF09453   HIRA_B

Interpro

IPR036396   Cyt_P450_sf        + More
IPR002401   Cyt_P450_E_grp-I       
IPR001128   Cyt_P450       
IPR017972   Cyt_P450_CS       
IPR019015   HIRA_B_motif       
IPR002403   Cyt_P450_E_grp-IV       
IPR002402   Cyt_P450_E_grp-II       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

L0N766   L0N7C5   D6MLU9   B6VFR9   A9YXV8   A4GUB9   + More
A5JM34   A9QW13   A5HG34   H9JUM4   A3RIC0   L0N6H5   A0A172MF86   D5L0M6   A0A0L7KJY7   A0A248QEX7   A0A0L7LJH7   A0A2A4J698   A0A068EWQ5   Q2XSW1   A0A068EU72   A0A068EVK6   A0A068F0X2   A0A0L7LRY0   A0A068EVD2   A0A2A4J2E3   A0A068EVL0   Q7YZS2   A0A0K8TUL3   A0A068ETU4   H2CZF1   H2CZE9   A0A0L7KVL1   A0A068EU65   F4YCW0   A0A3S2LFF7   A0A0K0YD30   Q069I9   A0A2A4JAM9   A0A2A4JAK3   A0A068ETU8   A0A248QHF4   A0A2A4J7V4   B3VT94   A0A248QEF8   A0A068F1Z7   A0A2H1V0E7   A0A2H1WID4   A0A2A4J918   J7FKN2   A0A0C5C1I6   A0A0K8TUI1   A0A3S2P9Y7   C1LZ54   J7FJF2   H9JUM8   A4GUB8   A0A437B5H6   A0A1V0D9E0   A0A1V0D9D9   A0A0N1IP03   A0A1V0D9D6   J7FKN1   A0A068EWQ0   X5D9B5   A0A411E5Q0   A0A0A7DH57   A0A2H1V048   A0A0N1ID06   A0A286QUG7   D2JLK6   W5VY13   A9QW15   A0A3S2LW02   A5HKM1   A0A0C5CGV6   A0A2A4JWC6   A0A222NX20   A0A0K8TV92   A0A2W1BGY9   L0N6M3   C7U1L4   A0A068F0X7   A0A248QG18   A0A0A7DH10   H9JUM5   J7FJF3   A0A2H1VU17   A0A248QEH8   A0A0A7DGX3   A0A0A7DH65   A5HG33   H9JUM6   A0A411AG09   A0A0A7DG86   D5L0M5   A0A0A7DH14   A0A2H1VSH4   A0A2H1VSG7  

PDB

5VCG     E-value=5.27986e-52,     Score=518

KEGG

100196930    K14999 cytochrome P450 family 6 [EC:1.14.-.-] | (RefSeq) cyp6a8, CYP6AE2; cytochrome P450 Cyp6ae21

GO

GO:0004497   GO:0005506   GO:0016705   GO:0020037   GO:0016021   GO:0046872   GO:0003824   GO:0008152   GO:0006468   GO:0004672   GO:0030677   GO:0016155   GO:0055114  

Length:

523

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

25.12513

Exp number, first 60 AAs:

21.43395

Total prob of N-in:

0.59126

POSSIBLE N-term signal

sequence

inside

1  -  4

TMhelix

5  -  22

outside

23  -  523

 

 

Pi

277.292734

Theta

167.714848

Tajima's D

1.873104

CLR

0

CSRT

0.864756762161892

Interpretation

Uncertain