Gene

KWMTBOMO09916

Pre Gene Modal

BGIBMGA013252

Annotation

PREDICTED:_CCR4-NOT_transcription_complex_subunit_10-like_[Amyelois_transitella]

Location

Bomo_Chr16(-):12022386-12024313      View in EpiBrowser

Full name

CCR4-NOT transcription complex subunit 10      

Location in the cell

Golgi   Reliability : 1.05

CDS

ATGTCAAACAACAAAGATCGCGATGAACCTGCTTTTTTAGCTCACCAATGTTTCTTAAAAAAGGACTACACAGCGGCATTACAACATCTTAGCGACTTGGAAAACCTTGTGGGAACTTCGAATAAAAGGGTTCAACACAACAAAGCCGTTGTAGAGTTTATGGCTGGAGAGATGAAGAATGTGGAAAAATTCAAAAATGCCATTACACAGTTATCAGGGTTAAATTATTTGGACGTCGAAGTCAAGGATATGACTTCACCCTGTTTGTTGTATAATTACGCGGTTATTCTGTTCCATTCACGTTATTATTATCAATGTGTTGTCATATTAGAGAAATTATTAAGTTCTAAGAGCATAAAAGATGCGAGATTACTACAGCAAATTATCTTACTTATGTTAGAAGCAACAATATGTCGACGTACTTATGATAAGACTATAGAAATCGCCAAGAACCACGGCGAGCCATTAAAAATTAATAATGAAGTTAGTGAGTTATTTGAAAGGATTATATCACGTGCTCAATTATTAGTTGGCCAAAAAGTAAAATTAAACCTTAAGCCTGATTCCATAGAGAACATATTTGTTATAGCACAGCAACATTACATCAATGGTAATGTAAAGGAAGCAGCTAATATATTGGGATATTACAAAACCTTAAAGTACAATTATGATATGAAAACTCAAGGTGAAGAAATATGGTCTGCCGTAAATAATAATTTGGGTGTCATATATTTATCAATTAAAAAACCTTATTTAGCCTCAAAATATTTTCAGCATGCCATAAAAGAACATTTGAAAGCTATGGAGTGTGAGGACAGTGAAAAATTAATATCTTGTAAAGATAGATCACTTTATGTGTACAATTTGGGGTTAGCACTTTTAGGTACAAATAATTCAGAAGGTGCTTTTGAGTGCCTAGTTGAAGCTGCTAGACATTTTCCTAATAACCCACGAATTTGGCTTCATTTAGCTGAATGCTGTGTAAAGAAATGTTGCAGTGAAGAAGCTCAGCAATACACAGTAAAGAAATTGGGCAGTGGTCCCCACACACGAGTCTTACTCTCAAAAGAAATAAAAGCAAGATATTCCACATCTGGGGAATCTTTTGCAATACCATCATTATCACTGGAATTTGCTGCACTATGTCTACGGAATGCTATGACTCTACTTCCCAACCAAGAACCTCCAGCGGATGTAACTGCATCACTTATACAAGTACCACCAGGTATCCCAATAACCTGGAAACAACGTAGCGAACTCAAGAACTCTGCCCTCGTTTTACAAAGTTATGTATTACTGCACTTGCAAGATCCATTAGCGGCTCTTGTCAGTGCCAATGAGTTACTAGCTCAACCAGACGCATCTAGTAGTCATAAAGCATGGGCTCACATATATGCAGCTGAAGCTCTCATAAATCTTGATCGAATAGCTGATGCTGTGGAGCATCTACATCCACCAACAATTCATGACTTAGTTTCAGTACTGCCGTATCAAATGAGGGATATGATTGCTGTATCTGTGTGGGCTAAAGCTGCAGTGTGTCATATTTTAAGAGGGGATCTAGTAACAGCAAAAAAGATACTTTTACAAATAAATTCACCAAAAGTTCTACCTCTACAGATGTATTTAGAGATTTGCACAGGTAATATAGACAATTGTCACACAATATTGAGAAAGATTAGATACACAAATCCCTCCATTCAATAA

Protein

MSNNKDRDEPAFLAHQCFLKKDYTAALQHLSDLENLVGTSNKRVQHNKAVVEFMAGEMKNVEKFKNAITQLSGLNYLDVEVKDMTSPCLLYNYAVILFHSRYYYQCVVILEKLLSSKSIKDARLLQQIILLMLEATICRRTYDKTIEIAKNHGEPLKINNEVSELFERIISRAQLLVGQKVKLNLKPDSIENIFVIAQQHYINGNVKEAANILGYYKTLKYNYDMKTQGEEIWSAVNNNLGVIYLSIKKPYLASKYFQHAIKEHLKAMECEDSEKLISCKDRSLYVYNLGLALLGTNNSEGAFECLVEAARHFPNNPRIWLHLAECCVKKCCSEEAQQYTVKKLGSGPHTRVLLSKEIKARYSTSGESFAIPSLSLEFAALCLRNAMTLLPNQEPPADVTASLIQVPPGIPITWKQRSELKNSALVLQSYVLLHLQDPLAALVSANELLAQPDASSSHKAWAHIYAAEALINLDRIADAVEHLHPPTIHDLVSVLPYQMRDMIAVSVWAKAAVCHILRGDLVTAKKILLQINSPKVLPLQMYLEICTGNIDNCHTILRKIRYTNPSIQ

Description

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex (By similarity).
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.

Subunit

Component of the CCR4-NOT complex; distinct complexes seem to exist that differ in the participation of probably mutually exclusive catalytic subunits. CNOT10 and CNOT11 form a subcomplex docked to the CNOT1 scaffold (By similarity).
Component of the CCR4-NOT complex; distinct complexes seem to exist that differ in the participation of probably mutually exclusive catalytic subunits. CNOT10 and CNOT11 form a subcomplex docked to the CNOT1 scaffold.

Similarity

Belongs to the CNOT10 family.

Keywords

Acetylation   Complete proteome   Cytoplasm   Nucleus   Reference proteome   RNA-mediated gene silencing   Transcription   Transcription regulation   Translation regulation   Alternative splicing   Coiled coil   Polymorphism  

Feature

chain  CCR4-NOT transcription complex subunit 10
splice variant  In isoform 6.
sequence variant  In dbSNP:rs11558687.

Uniprot

H9JUN9   L0N7B9   A0A2W1BP10   A0A2A4JIB1   A0A2H1V803   A0A0N1I8G4   + More
A0A194PJF6   A0A0L7KZ21   S4PG32   A0A1E1VXF0   A0A212F249   A0A1Y1M9J2   A0A1Y1MCD7   A0A084VH53   D6WQ07   A0A182PDC0   A0A182YFV7   A0A182IP89   A0A182M8F1   A0A336LTU4   A0A336K921   A0A182TR40   A0A182XN46   A0A182LM74   A0A182HI88   A0A1B6E480   A0A182JYA8   A0A2K5PS57   Q5XIA4   A0A182VH21   A0A1S3HDH2   A0A1S4H2M9   A0A182NBI0   A0A061I5Q3   Q8BH15-3   A0A182VTY6   V4AXB5   Q8BH15-2   A0A1U8C9Q5   A0A1U7QUP2   Q8BH15   M1EIM6   A0A182R3X1   N6UEA0   A0A2I3TE87   U6CUP7   A0A250Y4Q9   A0A154PRE8   A0A061I7V6   A0A2K6UVT1   A0A287AXZ3   A0A2Y9KVR8   L5L3W9   A0A452I509   G3H2P5   Q4R350   A0A2Y9L0Y9   A0A452I544   A0A2Y9KT91   A0A3Q7TQW6   A0A1S3G7E2   A0A3Q7UG43   A0A3Q2HI92   A0A3Q2HMX3   A0A3Q7U2T5   A0A3Q2LID5   A0A0P6JJ98   A0A2I3GAF2   A0A2R8ZSC2   G1QWN2   A0A2R8ZY54   A0A2K6R7D0   A0A2K6DBN9   G3RPD6   A0A2K5YA06   A0A2K5M7K2   G7NYB5   K7BLC0   I0FLB2   Q9H9A5   A0A096NQB5   K7BCN0   A0A2I2ZHA5   A0A2K6R7F2   H2PB90   A0A2I3SDV8   A0A1S3WCH2   A0A2J8WYS3   A0A2R8ZSB5   D2HB05   A0A287A7Y4   A0A2I3S5M4   A0A2I3GMJ1   A0A2K5PSA9   Q7Q1Q8   A0A2Y9G2V1   I3MPA8   Q9H9A5-6   A0A2K5PS20   A0A1S3WD30  

Pubmed

19121390    28756777    26354079    26227816    23622113    22118469    + More
28004739    24438588    18362917    19820115    25244985    20966253    15489334    12364791    23929341    16141072    21183079    23254933    23236062    23537049    16136131    28087693    23258410    28562605    21804562    19892987    22722832    25362486    22398555    22002653    25319552    14702039    16641997    17974005    19413330    19558367    21269460    23232451    23221646    23303381    24275569    20010809   

EMBL

BABH01022754    AK289348    BAM73875.1    KZ150106    PZC73413.1    NWSH01001290    + More
PCG71835.1    ODYU01001161    SOQ36983.1    KQ460773    KPJ12436.1    KQ459602    KPI93168.1    JTDY01004241    KOB68400.1    GAIX01003797    JAA88763.1    GDQN01011648    JAT79406.1    AGBW02010783    OWR47793.1    GEZM01040032    JAV80985.1    GEZM01040030    JAV80987.1    ATLV01013143    KE524841    KFB37297.1    KQ971354    EFA06148.2    AXCM01002025    UFQS01000188    UFQT01000188    SSX00990.1    SSX21370.1    SSX00991.1    SSX21371.1    APCN01005656    GEDC01004558    JAS32740.1    BC083782    AAAB01008980    KE675745    ERE74796.1    AK029103    AK149944    AK161842    BC025554    BC036179    BC039183    BC047204    KB201262    ESO98211.1    JP007862    AER96459.1    APGK01025891    APGK01025892    KB740605    KB632095    ENN80040.1    ERL88756.1    AACZ04000207    AACZ04000208    HAAF01002193    CCP74019.1    GFFV01001328    JAV38617.1    KQ435022    KZC13924.1    ERE74797.1    AEMK02000085    KB030368    ELK17951.1    JH000118    EGW04710.1    AB179418    GEBF01002096    JAO01537.1    ADFV01172028    ADFV01172029    ADFV01172030    ADFV01172031    ADFV01172032    ADFV01172033    ADFV01172034    ADFV01172035    ADFV01172036    ADFV01172037    AJFE02091747    AJFE02091748    AJFE02091749    AJFE02091750    AJFE02091751    AJFE02091752    AJFE02091753    AJFE02091754    AJFE02091755    AJFE02091756    CABD030020604    CABD030020605    CABD030020606    CABD030020607    CABD030020608    CABD030020609    CABD030020610    CABD030020611    CABD030020612    CABD030020613    AQIA01037521    AQIA01037522    AQIA01037523    AQIA01037524    AQIA01037525    AQIA01037526    CM001277    EHH51738.1    GABF01001152    GABD01009970    JAA20993.1    JAA23130.1    JU320281    JU471837    JV045167    CM001254    AFE64037.1    AFH28641.1    AFI35238.1    EHH16818.1    AK021695    AK022576    AK022952    AK023227    AK027026    AK302196    AC138972    AC139452    CH471055    BC002928    BC002931    AL117639    AHZZ02021205    AHZZ02021206    GABC01006926    GABE01000157    NBAG03000225    JAA04412.1    JAA44582.1    PNI73793.1    ABGA01226343    ABGA01226344    ABGA01226345    ABGA01226346    ABGA01226347    ABGA01226348    ABGA01226349    ABGA01226350    ABGA01226351    ABGA01226352    NDHI03003375    PNJ74916.1    GL192643    EFB27836.1    PNI73796.1    EAA14533.4    AGTP01006691    AGTP01006692    AGTP01006693    AGTP01006694    AGTP01006695    AGTP01006696   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000037510    UP000007151    + More
UP000030765    UP000007266    UP000075885    UP000076408    UP000075880    UP000075883    UP000075902    UP000076407    UP000075882    UP000075840    UP000075881    UP000233040    UP000002494    UP000075903    UP000085678    UP000075884    UP000030759    UP000000589    UP000075920    UP000030746    UP000189706    UP000075900    UP000019118    UP000030742    UP000002277    UP000076502    UP000233220    UP000008227    UP000248482    UP000010552    UP000291020    UP000001075    UP000233100    UP000286640    UP000081671    UP000002281    UP000001073    UP000240080    UP000233200    UP000233120    UP000001519    UP000233140    UP000233060    UP000009130    UP000005640    UP000028761    UP000001595    UP000079721    UP000007062    UP000248481    UP000005215   

PRIDE

H9JUN9    L0N7B9    Q5XIA4    Q8BH15    G3H2P5    Q4R350    + More
Q9H9A5   

Pfam

PF00685   Sulfotransfer_1        + More
PF13174   TPR_6
PF13181   TPR_8
PF04389   Peptidase_M28

Interpro

IPR019734   TPR_repeat        + More
IPR011990   TPR-like_helical_dom_sf       
IPR039740   CNOT10       
IPR027417   P-loop_NTPase       
IPR000863   Sulfotransferase_dom       
IPR013026   TPR-contain_dom       
IPR007484   Peptidase_M28       
IPR037457   M28_QC       

SUPFAM

SSF48452   SSF48452        + More
SSF52540   SSF52540       

Gene 3D

1.25.40.10    

CDD

cd03880  M28_QC_like

ProteinModelPortal

H9JUN9   L0N7B9   A0A2W1BP10   A0A2A4JIB1   A0A2H1V803   A0A0N1I8G4   + More
A0A194PJF6   A0A0L7KZ21   S4PG32   A0A1E1VXF0   A0A212F249   A0A1Y1M9J2   A0A1Y1MCD7   A0A084VH53   D6WQ07   A0A182PDC0   A0A182YFV7   A0A182IP89   A0A182M8F1   A0A336LTU4   A0A336K921   A0A182TR40   A0A182XN46   A0A182LM74   A0A182HI88   A0A1B6E480   A0A182JYA8   A0A2K5PS57   Q5XIA4   A0A182VH21   A0A1S3HDH2   A0A1S4H2M9   A0A182NBI0   A0A061I5Q3   Q8BH15-3   A0A182VTY6   V4AXB5   Q8BH15-2   A0A1U8C9Q5   A0A1U7QUP2   Q8BH15   M1EIM6   A0A182R3X1   N6UEA0   A0A2I3TE87   U6CUP7   A0A250Y4Q9   A0A154PRE8   A0A061I7V6   A0A2K6UVT1   A0A287AXZ3   A0A2Y9KVR8   L5L3W9   A0A452I509   G3H2P5   Q4R350   A0A2Y9L0Y9   A0A452I544   A0A2Y9KT91   A0A3Q7TQW6   A0A1S3G7E2   A0A3Q7UG43   A0A3Q2HI92   A0A3Q2HMX3   A0A3Q7U2T5   A0A3Q2LID5   A0A0P6JJ98   A0A2I3GAF2   A0A2R8ZSC2   G1QWN2   A0A2R8ZY54   A0A2K6R7D0   A0A2K6DBN9   G3RPD6   A0A2K5YA06   A0A2K5M7K2   G7NYB5   K7BLC0   I0FLB2   Q9H9A5   A0A096NQB5   K7BCN0   A0A2I2ZHA5   A0A2K6R7F2   H2PB90   A0A2I3SDV8   A0A1S3WCH2   A0A2J8WYS3   A0A2R8ZSB5   D2HB05   A0A287A7Y4   A0A2I3S5M4   A0A2I3GMJ1   A0A2K5PSA9   Q7Q1Q8   A0A2Y9G2V1   I3MPA8   Q9H9A5-6   A0A2K5PS20   A0A1S3WD30  

KEGG

101743918    K12607 CCR4-NOT transcription complex subunit 10 | (RefSeq) CCR4-NOT transcription complex subunit 1

PATHWAY

03018    RNA degradation - Bombyx mori (domestic silkworm)

GO

GO:0030014   GO:0016021   GO:0008146   GO:0017148   GO:0006402   GO:0031047   GO:0005634   GO:0005737   GO:0016603   GO:0006417   GO:0005829   GO:0006977   GO:0000289   GO:0016020   GO:0005515   GO:0003723   GO:0004540   GO:0005655   GO:0006364   GO:0006379   GO:0008033   GO:0030677   GO:0016155   GO:0003824  

PANTHER

PTHR12979  

Subcellular location

Cytoplasm  
Nucleus  

Length:

568

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.283640000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01606

outside

1  -  568

 

 

Pi

14.149505

Theta

14.293748

Tajima's D

0.219116

CLR

0.588536

CSRT

0.43712814359282

Interpretation

Uncertain