Gene

KWMTBOMO09896

Pre Gene Modal

BGIBMGA013264

Annotation

PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_21_[Papilio_polytes]

Location

Bomo_Chr16(-):11465942-11467413      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 21      

Alternative Name

Mediator complex subunit 21

Location in the cell

Cytoplasmic   Reliability : 1.514 Nuclear   Reliability : 2.1

CDS

ATGGCTGATCGCTTAACTCAGCTTCAAGATACCATAAACCAACAAGCTGAGAATTTTTGTAACAGCATCGGAATTCTACAGCAGTTCTCGTTGCCTAGCAAGTTCCCAGGCTTCGAACGCGGTGGTTCTCAGACTCCTCAACAACCGCAGAGTCAAGAGGATTATGCGGTTTTATTCGCGGCTCTAATTTCTCGTTGTGCTAAGGACATTGACACGCTCATCGAGTCTTTGCCCAGTGAAGAGAGTTCAACTGAGCTGCAAGTGCAAAGCCTTCGGCGACTTGAGGCCGAGAACAAGGAGGCTGCTGAGCAACTTGAAGAGGTAGTCCGTCAAGGAGAGATTCTTCTAGAGAAGATTCAGGGTGCTCTGAGTGATATTGCTCAGTGCCAGTTGGACATGCAGAATCCGGCTCTGATCCTCAACAAGGATGTGAAACCACAGTTATAG

Protein

MADRLTQLQDTINQQAENFCNSIGILQQFSLPSKFPGFERGGSQTPQQPQSQEDYAVLFAALISRCAKDIDTLIESLPSEESSTELQVQSLRRLEAENKEAAEQLEEVVRQGEILLEKIQGALSDIAQCQLDMQNPALILNKDVKPQL

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 21 family.

Keywords

Activator   Coiled coil   Complete proteome   Nucleus   Reference proteome   Transcription   Transcription regulation  

Feature

chain  Mediator of RNA polymerase II transcription subunit 21

Uniprot

H9JUQ1   A0A2A4J726   A0A0N1I6N9   A0A2H1VY38   A0A194PPX7   A0A1E1WF79   + More
A0A3S2LUF4   S4PVG2   A0A212F252   E2C3Y4   A0A0C9QZV1   E9ITE6   A0A195FCY1   F4X8N5   A0A195BAJ8   A0A158NBJ0   A0A195DRG2   A0A151IGZ5   A0A310SMS2   B0X1T2   A0A0L7RES2   K7IQX6   Q16RX1   A0A1Q3F936   A0A023EE41   A0A0J7L9L5   A0A232EUM8   A0A154NWK2   A0A026W691   A0A182MTD0   A0A182RH45   A0A182VQ28   A0A182SR49   A0A182JT55   A0A182Y4Q1   A0A2M3ZCJ9   A0A2M4AZA6   A0A182FSW7   W5J791   A0A182R0J0   A0A182NMP1   U5EZ57   A0A182JJ77   A0A0K8TKA4   A0A336KIX0   A0A084VB93   A0A2J7QH52   A0A1B6GV26   A0A1B6J2N0   A0A1A9W881   A0A1B6KCI3   A0A088AFW9   A0A1I8Q4I5   A0A1L8EBX8   A0A0N7Z8Z6   R4FMF2   A0A1I8N9J1   A0A0M4EKX6   A0A224XNH3   A0A1S4N3B4   A0A182HZG3   A0A0L0C9E5   B4K4H7   A0A182X397   Q7PTL0   B4NIW6   A0A1A9XAG9   A0A1Y1MPT2   A0A1B0G1J5   A0A1A9UN40   A0A1B0AA58   A0A1L8DFN6   A0A0A9Y3U1   B4JYT3   A0A1L8DHN0   A0A1B0EZG0   A0A182UZB9   A0A2A3EGL0   W8BUU9   B4LVY6   D2A454   A0A067RF90   A0A2R7X3F0   E0W3P2   A0A0A1WX94   A0A1W4UG91   A0A3B0K251   A0A3B0KSZ6   J3JV76   A0A0C9RH92   A0A034VLR6   B4PT19   A0A1S3DI38   B5DVQ1   B4GM95   A0A0K8W4S9   B3P248   A0A3B0KIK9   A0A0P8XDV8   B4ILS2  

Pubmed

19121390    26354079    23622113    22118469    20798317    21282665    + More
21719571    21347285    20075255    17510324    24945155    26483478    28648823    24508170    30249741    25244985    20920257    23761445    26369729    24438588    27129103    25315136    20566863    26108605    17994087    12364791    28004739    25401762    26823975    24495485    18362917    19820115    24845553    25830018    22516182    25348373    17550304    15632085   

EMBL

BABH01022814    NWSH01002689    PCG67679.1    KQ461178    KPJ07778.1    ODYU01005159    + More
SOQ45749.1    KQ459602    KPI93185.1    GDQN01005477    JAT85577.1    RSAL01000008    RVE53993.1    GAIX01008593    JAA83967.1    AGBW02010783    OWR47801.1    GL452364    EFN77370.1    GBYB01009314    JAG79081.1    GL765542    EFZ16158.1    KQ981673    KYN38246.1    GL888932    EGI57304.1    KQ976540    KYM81257.1    ADTU01011116    KQ980581    KYN15397.1    KQ977661    KYN00705.1    KQ761108    OAD58202.1    DS232269    EDS38810.1    KQ414609    KOC69334.1    CH477694    GFDL01010954    JAV24091.1    JXUM01048228    GAPW01005725    KQ561553    JAC07873.1    KXJ78179.1    LBMM01000150    KMR04730.1    NNAY01002107    OXU22060.1    KQ434775    KZC04059.1    KK107453    QOIP01000004    EZA50564.1    RLU23454.1    AXCM01000279    GGFM01005429    MBW26180.1    GGFK01012764    MBW46085.1    ADMH02002125    ETN58654.1    AXCN02001211    GANO01001393    JAB58478.1    AXCP01009189    GDAI01002944    JAI14659.1    UFQS01000367    UFQS01002249    UFQT01000367    UFQT01002249    SSX03215.1    SSX13596.1    SSX23581.1    ATLV01006107    ATLV01006108    KE524339    KFB35237.1    NEVH01014358    PNF27912.1    GECZ01003471    JAS66298.1    GECU01036591    GECU01014284    JAS71115.1    JAS93422.1    GEBQ01030831    JAT09146.1    GFDG01002541    JAV16258.1    GDKW01001963    JAI54632.1    ACPB03004193    GAHY01001734    JAA75776.1    CP012526    ALC47946.1    GFTR01002380    JAW14046.1    AAZO01007430    APCN01001975    JRES01000826    KNC28059.1    CH933806    EDW13929.1    AAAB01008799    CH964272    EDW84868.1    GEZM01024974    JAV87661.1    CCAG010017948    GFDF01008897    JAV05187.1    GBHO01021205    GBHO01019429    GBRD01014463    GBRD01008325    GDHC01019250    GDHC01014959    JAG22399.1    JAG24175.1    JAG51363.1    JAP99378.1    JAQ03670.1    CH916378    EDV98548.1    GFDF01008128    JAV05956.1    AJWK01022430    KZ288254    PBC30850.1    GAMC01005812    JAC00744.1    CH940650    EDW66491.1    KQ971348    EFA04844.1    KK852507    KDR22437.1    KK856724    PTY26329.1    DS235882    EEB20248.1    GBXI01011051    JAD03241.1    OUUW01000014    SPP88347.1    SPP88351.1    BT127143    AEE62105.1    GBYB01012577    JAG82344.1    GAKP01014701    JAC44251.1    CM000160    EDW95608.1    CM000070    EDY68459.1    CH479185    EDW37969.1    GDHF01024329    GDHF01006203    JAI27985.1    JAI46111.1    CH954181    EDV47726.1    SPP88350.1    CH902623    KPU72690.1    CH480886    EDW55364.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000007151    + More
UP000008237    UP000078541    UP000007755    UP000078540    UP000005205    UP000078492    UP000078542    UP000002320    UP000053825    UP000002358    UP000008820    UP000069940    UP000249989    UP000036403    UP000215335    UP000076502    UP000053097    UP000279307    UP000075883    UP000075900    UP000075920    UP000075901    UP000075881    UP000076408    UP000069272    UP000000673    UP000075886    UP000075884    UP000075880    UP000030765    UP000235965    UP000091820    UP000005203    UP000095300    UP000015103    UP000095301    UP000092553    UP000075840    UP000037069    UP000009192    UP000076407    UP000007062    UP000007798    UP000092443    UP000092444    UP000078200    UP000092445    UP000001070    UP000092461    UP000075903    UP000242457    UP000008792    UP000007266    UP000027135    UP000009046    UP000192221    UP000268350    UP000002282    UP000079169    UP000001819    UP000008744    UP000008711    UP000007801    UP000001292   

PRIDE

H9JUQ1    Q16RX1    Q7PTL0   

Pfam

PF11221   Med21        + More
PF01926   MMR_HSR1

Interpro

IPR021384   Mediator_Med21        + More
IPR037212   Med7/Med21-like       
IPR031167   G_OBG       
IPR006073   GTP_binding_domain       
IPR027417   P-loop_NTPase       

SUPFAM

SSF140718   SSF140718        + More
SSF52540   SSF52540       

ProteinModelPortal

H9JUQ1   A0A2A4J726   A0A0N1I6N9   A0A2H1VY38   A0A194PPX7   A0A1E1WF79   + More
A0A3S2LUF4   S4PVG2   A0A212F252   E2C3Y4   A0A0C9QZV1   E9ITE6   A0A195FCY1   F4X8N5   A0A195BAJ8   A0A158NBJ0   A0A195DRG2   A0A151IGZ5   A0A310SMS2   B0X1T2   A0A0L7RES2   K7IQX6   Q16RX1   A0A1Q3F936   A0A023EE41   A0A0J7L9L5   A0A232EUM8   A0A154NWK2   A0A026W691   A0A182MTD0   A0A182RH45   A0A182VQ28   A0A182SR49   A0A182JT55   A0A182Y4Q1   A0A2M3ZCJ9   A0A2M4AZA6   A0A182FSW7   W5J791   A0A182R0J0   A0A182NMP1   U5EZ57   A0A182JJ77   A0A0K8TKA4   A0A336KIX0   A0A084VB93   A0A2J7QH52   A0A1B6GV26   A0A1B6J2N0   A0A1A9W881   A0A1B6KCI3   A0A088AFW9   A0A1I8Q4I5   A0A1L8EBX8   A0A0N7Z8Z6   R4FMF2   A0A1I8N9J1   A0A0M4EKX6   A0A224XNH3   A0A1S4N3B4   A0A182HZG3   A0A0L0C9E5   B4K4H7   A0A182X397   Q7PTL0   B4NIW6   A0A1A9XAG9   A0A1Y1MPT2   A0A1B0G1J5   A0A1A9UN40   A0A1B0AA58   A0A1L8DFN6   A0A0A9Y3U1   B4JYT3   A0A1L8DHN0   A0A1B0EZG0   A0A182UZB9   A0A2A3EGL0   W8BUU9   B4LVY6   D2A454   A0A067RF90   A0A2R7X3F0   E0W3P2   A0A0A1WX94   A0A1W4UG91   A0A3B0K251   A0A3B0KSZ6   J3JV76   A0A0C9RH92   A0A034VLR6   B4PT19   A0A1S3DI38   B5DVQ1   B4GM95   A0A0K8W4S9   B3P248   A0A3B0KIK9   A0A0P8XDV8   B4ILS2  

KEGG

101745555    K15152 mediator of RNA polymerase II transcription subunit 21 | (RefSeq) mediator of RNA polymerase

GO

GO:0016592   GO:0005634   GO:0005525   GO:0006357   GO:0003712   GO:0016021   GO:0003713  

PANTHER

PTHR13381  

Subcellular location

Nucleus  

Length:

148

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0004

Exp number, first 60 AAs:

0.0004

Total prob of N-in:

0.22775

outside

1  -  148

 

 

Pi

326.065362

Theta

205.640575

Tajima's D

1.857407

CLR

0.011804

CSRT

0.857457127143643

Interpretation

Uncertain