SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO09885  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA013160
Annotation
3-dehydroecdysone_3alpha-reductase_[Bombyx_mori]
Location in the cell
Cytoplasmic   Reliability : 1.059
 

Sequence

CDS
ATGAGTTTCACAAATAAAGTGGTTCTCGTCACCGGCGGCAGCTCGGGTATCGGTGCCTCTGCCGCCGTACACTTCGCTAAGGAAGGTGCGGACGTGGCCATAGTAGGTCGTAACGTTACGAAACTGGACAACGTGGCCCGGGAATGTGCGCAGGTCGGCAAAAAGCCGCTCATCATTAAAGCTGACATTTCAAACGACGAAGAAGCGAAGACCATCGTTCAGCAAACCATTGACGCCTTCGGGAAGCTAGATGTGCTCATTAACAACGCTGGAATGAACAAATCCGGGTCCCTGCTCGCTGGCAACCTCCTTGAATCGTACGACGCAGTCACAGCGACTAATCTGAGAGCGGTCATTTTGATAACGAGCCTTGCGGCTCCGCACCTCATCGAGACGAAGGGAAACATCATAAACGTATCCAGTATCGGTGGAACCATGGTACCAATGCCAGGGTTTCTTGCATACTGCATGGGGAAAGCTAGTTTGAATCATTTTACGCGTGGTATTGCCTTGGAATTAGCTCCTCGTGGTGTCAGAGCAAACATTATCAGTCCAGGTCCTGTTTTAACTGATATCATTGAGAATTCTGATAATCAGATTAGCTGGGACATTTTTAGGGCTGCCACGGCGTTGAAGAAATTAGGAGAACCGTCAGAAATAGCGGAGTTGATGTTGTTCCTGGCAAGTGACAAAGCTAGAAGCATAACTGGCTCGAACTACGTCTCCGACAATGGAATGCTGCTGCTCAGATGA
Protein
MSFTNKVVLVTGGSSGIGASAAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSNYVSDNGMLLLR

Summary

Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
EMBL
JF433973    AEM17060.1    BABH01022835    BABH01022833    BABH01022834    KQ461178    + More
KPJ07784.1    KQ460655    KPJ12939.1    KPJ07786.1    AK405443    BAM20756.1    KQ459602    KPI93179.1    KPJ07785.1    KPJ12938.1    KQ459595    KPI95966.1    KPI93176.1    KQ459579    KPI99448.1    JTDY01000942    KOB75350.1    JTDY01006084    KOB66312.1    KPI95964.1    ODYU01013212    SOQ59906.1    KQ460650    KPJ13113.1    AGBW02014512    OWR41545.1    KPI93178.1    KPJ12937.1    KQ460571    KPJ13957.1    NWSH01001398    PCG71373.1    ODYU01001522    SOQ37852.1    OWR41546.1    AGBW02013539    OWR43254.1    NWSH01004416    PCG65151.1    KQ459580    KPI99297.1    KPI93177.1    BABH01012981    BABH01022634    SOQ37854.1    ODYU01000551    SOQ35503.1    NWSH01006959    PCG63175.1    KPI95965.1    PCG71375.1    NWSH01001353    PCG71567.1    JTDY01009080    KOB64125.1    PCG71374.1    AF255341    AAF70499.1    BABH01022635    BABH01022636    LADJ01004337    KPJ20878.1    AK404043    BAM20116.1    AK401409    BAM18031.1    JTDY01004206    KOB68460.1    PCG71376.1    AGBW02010783    OWR47824.1    NWSH01003146    PCG66863.1    ODYU01010994    SOQ56451.1    PCG65150.1    SOQ37853.1    PCG65149.1    KOB66313.1    ODYU01002398    SOQ39832.1    ODYU01008068    SOQ51354.1    PCG65148.1    JTDY01008777    KOB64404.1    JTDY01001151    KOB74729.1    ODYU01011234    SOQ56848.1    ODYU01009744    SOQ54378.1    ODYU01010604    SOQ55826.1    OWR43255.1    KZ149910    PZC78149.1    KQ459717    KPJ20326.1    PZC78150.1    EZ407245    ACX53802.1    PCG71569.1    PZC78151.1    AGBW02010784    OWR47781.1    AGBW02012537    OWR44869.1    KQ459596    KPI95296.1    JTDY01000816    KOB75772.1    OWR47820.1    KQ460317    KPJ16010.1    KOB64405.1    PCG71568.1    KQ460643    KPJ13319.1    ODYU01005275    SOQ45968.1    NWSH01001143    PCG72417.1    ODYU01010177    SOQ55120.1    NWSH01000090    PCG79695.1    ODYU01012735    SOQ59194.1    JTDY01007623    KOB65070.1    ODYU01006626    SOQ48636.1    BT126415    KB632402    AEE61379.1    ERL94969.1    JTDY01004127    KOB68555.1    CAEY01000740    GL888128    EGI66781.1    NWSH01005813    PCG63919.1    KQ971312    EEZ97890.1    KQ982320    KYQ57786.1    GEDC01013050    GEDC01009962    GEDC01006526    JAS24248.1    JAS27336.1    JAS30772.1    GL888223    EGI64444.1    KK854833    PTY19106.1    KQ459604    KPI92523.1   
Pfam
PF00106   adh_short        + More
PF00650   CRAL_TRIO
PF00292   PAX
Interpro
IPR036291   NAD(P)-bd_dom_sf        + More
IPR020904   Sc_DH/Rdtase_CS       
IPR002347   SDR_fam       
IPR036865   CRAL-TRIO_dom_sf       
IPR001251   CRAL-TRIO_dom       
IPR036388   WH-like_DNA-bd_sf       
IPR009057   Homeobox-like_sf       
IPR001523   Paired_dom       
SUPFAM
SSF51735   SSF51735        + More
SSF52087   SSF52087       
SSF46689   SSF46689       
Gene 3D
PDB
1SPX     E-value=1.2388e-31,     Score=338

Ontologies

Topology

Subcellular location
Nucleus  
Length:
250
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
6.05294999999999
Exp number, first 60 AAs:
3.82583
Total prob of N-in:
0.25120
outside
1  -  250
 
 

Population Genetic Test Statistics

Pi
238.432588
Theta
184.789078
Tajima's D
0.865292
CLR
0.568808
CSRT
0.623668816559172
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
28556443 GIALELAPR 95.45 2e-07
28556443 SGLAAYIFTK 95.45 2e-07
28556443 NIVQQTIDAFGK 100.00 5e-05
28556443 EGADVAIVGR 100.00 2e-04
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