Gene

KWMTBOMO09884  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013160

Annotation

3-dehydroecdysone_3alpha-reductase_[Bombyx_mori]

Location

Bomo_Chr16(+):11216544-11217446      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.152

CDS

ATGAGTTTCACAAATAAAGTGGTTCTCGTCACCGGGGGCAGCTCGGGTATCGGTGCCTCTGCCGCCGTACACTTCGCTAAGGAAGGTGCGGACGTGGCCATAGTAGGTCGAAACGTTACGAAACTGGACAACGTGGCCCGGGAATGTGCGCAAGTCGGCAAAAAGCCGGTCATCATTAAAGCTGACATTTCAAAAGACGAAGAAGCGAAGACCATCGTTCAACAAACCATTGAAGCCTTCGGGAAGCTAGATGTGCTCATTAACAACGCTGGAATGAACAAATCCGGGTCCCTGCTCGCTGGCAACCTCCTTGAATCGTACGACGCAGTCACAGCGACTAATCTGAGAGCGGTCATTTTGATAACGAGCCTCGCTGCTCCGCACCTCATCGAGACGAAGGGAAACATCATAAACGTATCCAGTATCGGCGGAACCATGGTACCAATGCCAGGGTTTCTGGCATACTGCATGGGGAAAGCTAGTTTGAATCATTTTACGCGTGGTATTGCCTTGGAATTAGCACCTCATGGTGTCAGAGCAAACATCATCAGTCCAGGTCTTGTTTTAACTGATATCATTGAGAACTCTGATAATCAGATTAGCTGGGACATTTTTAGGGCTGCCACGGCGTTGAAGAAATTAGGAGAACCGTCAGAAATTGCCGAGTTGATGTTGTTCCTGGCAAGTGACAAAGCTAGAAGCATAACTGGCTCGAACTACGTCTCCGACAATGGAATGCTGCTGCTCAGATGA

Protein

MSFTNKVVLVTGGSSGIGASAAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPVIIKADISKDEEAKTIVQQTIEAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPHGVRANIISPGLVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSNYVSDNGMLLLR

Similarity

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Uniprot

H6AGY1   H9JUE7   H9JUQ7   H9JUQ8   H9JUE8   A0A0N0PAS3   + More
A0A0N1PFW5   A0A0N0PB24   I4DS66   A0A0N1IFH9   A0A194PKC3   A0A194PID7   A0A194PR87   A0A0N1IGV7   A0A194Q286   A0A0N0PC39   A0A0N1IDX2   A0A0N1IHB9   A0A194PJG5   A0A0L7KSS2   A0A0L7LIU8   A0A2A4JIX4   A0A2H1X3T6   A0A194PT74   A0A2A4IZG3   A0A212EJ88   A0A2H1VBR9   A0A194PIN0   A0A194Q138   H9JUK7   A0A2H1VC89   A0A212EP45   A0A212EJ84   H9JHN5   A0A2A4ITT1   A0A2A4JH23   A0A2H1V3T7   A0A194PXT8   A0A0L7KLX4   I4DJE1   I4DQC6   H9JUK8   A0A0N1PJN4   A0A2A4JIH1   A0A2A4JHN9   Q9NBB5   A0A2A4JHX2   A0A2A4J134   A0A2H1VAH5   A0A0L7KZ86   A0A2A4IZU2   A0A2H1WTS2   A0A2A4J612   A0A212F276   A0A0L7KSR6   A0A2H1WMX1   A0A2H1VHE2   A0A2A4J0E8   A0A2H1WFW5   A0A0N0PET2   A0A2H1WUW2   A0A2A4JIE3   A0A2W1BSW8   A0A0L7KN57   A0A0L7LH86   A0A212EP29   A0A2H1WS78   A0A2W1BZ77   H9JUI0   D2SNW1   A0A2W1BUV9   A0A212F231   A0A194PPC7   A0A0L7LK01   A0A0N1IIA2   A0A212ETR6   A0A0L7KMQ4   A0A0N0PCB2   A0A2A4JIM8   A0A212F250   H9JUH9   A0A2H1VYS0   A0A2A4JK27   A0A2H1X3K0   A0A0L7KPN2   A0A2A4K610   A0A2H1WPX2   A0A2H1W6Q5   A0A0L7KZH2   J3JT59   T1KZI5   A0A2A4IW86   A0A2A4K5A7   D6WBF1   A0A1S3D915   A0A194PHJ7   A0A151XBN1   A0A2R7WHM1   F4WG14   A0A158NXY9  

Pubmed

19121390    26354079    22651552    26227816    22118469    10861234    + More
28756777    20074338    22516182    23537049    18362917    19820115    21719571    21347285   

EMBL

JF433973    AEM17060.1    BABH01022835    BABH01022833    BABH01022834    KQ461178    + More
KPJ07784.1    KPJ07786.1    KPJ07785.1    AK405443    BAM20756.1    KQ460655    KPJ12939.1    KQ459602    KPI93179.1    KPI93176.1    KQ459595    KPI95966.1    KPJ12938.1    KQ459579    KPI99448.1    KPJ12937.1    KQ460650    KPJ13113.1    KQ460571    KPJ13957.1    KPI93178.1    JTDY01006084    KOB66312.1    JTDY01000942    KOB75350.1    NWSH01001398    PCG71373.1    ODYU01013212    SOQ59906.1    KPI95964.1    NWSH01004416    PCG65151.1    AGBW02014512    OWR41545.1    ODYU01001522    SOQ37852.1    KPI93177.1    KQ459580    KPI99297.1    BABH01022634    SOQ37854.1    AGBW02013539    OWR43254.1    OWR41546.1    BABH01012981    NWSH01006959    PCG63175.1    PCG71375.1    ODYU01000551    SOQ35503.1    KPI95965.1    JTDY01009080    KOB64125.1    AK401409    BAM18031.1    AK404043    BAM20116.1    BABH01022635    BABH01022636    LADJ01004337    KPJ20878.1    PCG71374.1    NWSH01001353    PCG71567.1    AF255341    AAF70499.1    PCG71376.1    PCG65150.1    SOQ37853.1    JTDY01004206    KOB68460.1    PCG65149.1    ODYU01010994    SOQ56451.1    NWSH01003146    PCG66863.1    AGBW02010783    OWR47824.1    KOB66313.1    ODYU01009744    SOQ54378.1    ODYU01002398    SOQ39832.1    PCG65148.1    ODYU01008068    SOQ51354.1    KQ459717    KPJ20326.1    ODYU01011234    SOQ56848.1    PCG71569.1    KZ149910    PZC78149.1    JTDY01008777    KOB64404.1    JTDY01001151    KOB74729.1    OWR43255.1    ODYU01010604    SOQ55826.1    PZC78150.1    EZ407245    ACX53802.1    PZC78151.1    AGBW02010784    OWR47781.1    KQ459596    KPI95296.1    JTDY01000816    KOB75772.1    KQ460317    KPJ16010.1    AGBW02012537    OWR44869.1    KOB64405.1    KQ460643    KPJ13319.1    PCG71568.1    OWR47820.1    ODYU01005275    SOQ45968.1    NWSH01001143    PCG72417.1    ODYU01012735    SOQ59194.1    JTDY01007623    KOB65070.1    NWSH01000090    PCG79695.1    ODYU01010177    SOQ55120.1    ODYU01006626    SOQ48636.1    JTDY01004127    KOB68555.1    BT126415    KB632402    AEE61379.1    ERL94969.1    CAEY01000740    NWSH01005813    PCG63919.1    NWSH01000134    PCG79206.1    KQ971312    EEZ97890.1    KQ459604    KPI92523.1    KQ982320    KYQ57786.1    KK854833    PTY19106.1    GL888128    EGI66781.1    ADTU01003750   

Proteomes

UP000005204    UP000053240    UP000053268    UP000037510    UP000218220    UP000007151    + More
UP000030742    UP000015104    UP000007266    UP000079169    UP000075809    UP000007755    UP000005205   

PRIDE

H6AGY1    H9JUE7    H9JUQ7    H9JUQ8    H9JUE8    H9JUK7    + More
H9JHN5    H9JUK8    H9JUI0    H9JUH9   

Pfam

PF00106   adh_short        + More
PF00650   CRAL_TRIO
PF00292   PAX

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR020904   Sc_DH/Rdtase_CS       
IPR002347   SDR_fam       
IPR036865   CRAL-TRIO_dom_sf       
IPR001251   CRAL-TRIO_dom       
IPR036388   WH-like_DNA-bd_sf       
IPR009057   Homeobox-like_sf       
IPR001523   Paired_dom       

SUPFAM

SSF51735   SSF51735        + More
SSF52087   SSF52087       
SSF46689   SSF46689       

Gene 3D

3.40.525.10     1.10.10.10    

CDD

cd00170  SEC14

ProteinModelPortal

H6AGY1   H9JUE7   H9JUQ7   H9JUQ8   H9JUE8   A0A0N0PAS3   + More
A0A0N1PFW5   A0A0N0PB24   I4DS66   A0A0N1IFH9   A0A194PKC3   A0A194PID7   A0A194PR87   A0A0N1IGV7   A0A194Q286   A0A0N0PC39   A0A0N1IDX2   A0A0N1IHB9   A0A194PJG5   A0A0L7KSS2   A0A0L7LIU8   A0A2A4JIX4   A0A2H1X3T6   A0A194PT74   A0A2A4IZG3   A0A212EJ88   A0A2H1VBR9   A0A194PIN0   A0A194Q138   H9JUK7   A0A2H1VC89   A0A212EP45   A0A212EJ84   H9JHN5   A0A2A4ITT1   A0A2A4JH23   A0A2H1V3T7   A0A194PXT8   A0A0L7KLX4   I4DJE1   I4DQC6   H9JUK8   A0A0N1PJN4   A0A2A4JIH1   A0A2A4JHN9   Q9NBB5   A0A2A4JHX2   A0A2A4J134   A0A2H1VAH5   A0A0L7KZ86   A0A2A4IZU2   A0A2H1WTS2   A0A2A4J612   A0A212F276   A0A0L7KSR6   A0A2H1WMX1   A0A2H1VHE2   A0A2A4J0E8   A0A2H1WFW5   A0A0N0PET2   A0A2H1WUW2   A0A2A4JIE3   A0A2W1BSW8   A0A0L7KN57   A0A0L7LH86   A0A212EP29   A0A2H1WS78   A0A2W1BZ77   H9JUI0   D2SNW1   A0A2W1BUV9   A0A212F231   A0A194PPC7   A0A0L7LK01   A0A0N1IIA2   A0A212ETR6   A0A0L7KMQ4   A0A0N0PCB2   A0A2A4JIM8   A0A212F250   H9JUH9   A0A2H1VYS0   A0A2A4JK27   A0A2H1X3K0   A0A0L7KPN2   A0A2A4K610   A0A2H1WPX2   A0A2H1W6Q5   A0A0L7KZH2   J3JT59   T1KZI5   A0A2A4IW86   A0A2A4K5A7   D6WBF1   A0A1S3D915   A0A194PHJ7   A0A151XBN1   A0A2R7WHM1   F4WG14   A0A158NXY9  

PDB

1SPX     E-value=3.81894e-33,     Score=351

KEGG

100862709    no KO assigned | (RefSeq) 3-dehydroecdysone 3alpha-reductase

GO

GO:0016491   GO:0016021   GO:0005634   GO:0007275   GO:0003677   GO:0006355   GO:0005622   GO:0006810   GO:0006412   GO:0006414   GO:0004816   GO:0005737   GO:0006421   GO:0016155   GO:0003824  

Subcellular location

Nucleus  

Length:

250

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

6.05448999999999

Exp number, first 60 AAs:

3.82522

Total prob of N-in:

0.25122

outside

1  -  250

 

 

Pi

238.654829

Theta

162.307843

Tajima's D

1.597254

CLR

0

CSRT

0.807759612019399

Interpretation

Uncertain