Gene

KWMTBOMO09875

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr16(+):11112494-11114828      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 2.037 PlasmaMembrane   Reliability : 1.338

CDS

ATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGGAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTTCTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACGAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCTCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGATGCCTTCAGCTCTAATACTAGGGGCAGGCTTAACGAGTACGGTTACCCCGGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAACCTAA

Protein

MEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKELQSAALALGQWFRKWRIDINPAKSSAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYETCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSNTRGRLNEYGYPGNRTRRTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   K9N5J5   A0A0N0PA09   A0A0N1PFV1   + More
O96546   O96544   A0A194Q1H8   A0A1Y1NA23   V5GNF3   A0A2S2PR14   V5GNJ2   A0A139WA11   X1WMU5   A0A139W8G9   X1WXU3   X1WLB2   J9KKL3   X1WWC4   A0A2S2PH29   V5I850   A0A2S2Q823   A0A2S2PX53   A0A087U2S8   A0A1Y1M7E9   J9KC83   A0A2S2QTZ8   A0A2S2PPK8   A0A2S2QJM7   A0A023EZE6   A0A2S2N814   A0A023EYS8   A0A224XF24   O76197   A0A2S2Q352   A0A2S2QEE0   A0A2S2RAN7   A0A2S2NJB5   J9LC15   A0A1Y1LKN6   A0A2J7R7D0   A0A2H8TWD9   A0A2J7RL12   A0A087T1W0   A0A087V0P8   A0A2S2NGV8   A0A2J7RS81   J9KCZ4   A0A2J7PVX3   A0A069DZC5   A0A2M4BDV6   A0A069DW01   A0A2H8U0H5   A0A2H8TES1   A0A2J7QPI2   J9M522   A0A2M4BD67   A0A2J7R579   A0A2A4K8E7   A0A023F6S4   X1WZH0   A0A2J7Q627   A0A3N5Z7I3   A0A2J7R8R8   A0A2J7R4B1   A0A0J7K4E0   A0A2J7PEB1   X1WN18   A0A0A9YJ00   X1WNI2   Q95SX7   A0A2J7PDM0   A0A023F7D1   A0A0C9RJA4   A0A2P8Z520   A0A2J7QB68   A0A2J7PQB5   A0A1Y1K0N4   A0A2S2Q383   A0A146LCK7   X1WTA1   A0A2S2PBB4   Q9NBX4   A0A2J7RIW7   A0A182GB02   A0A0A9YU04   A0A2J7R4B7   A0A2J7RM10   A0A2A4K918   A0A2J7Q4F7   A0A2J7QUJ9   A0A2J7Q059   Q07995   A0A2J7PMP6   A0A2J7RB54   A0A2S2R9D4   A0A0J7KBP6   A0A2J7RPU2   A0A139W9S2  

EC Number

2.7.7.49

Pubmed

10333566    23652563    26354079    10380107    28004739    18362917    + More
19820115    25474469    8934517    26334808    30086797    25401762    7753626    12537569    29403074    26823975    11405632    26483478    8387152   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KC165845    AFY12622.1    KQ459259    KPJ02068.1    KQ459265    KPJ02064.1    AF081103    AAC72921.1    AF081101    AAC72919.1    KQ459580    KPI99178.1    GEZM01008457    JAV94772.1    GALX01005359    JAB63107.1    GGMR01019198    MBY31817.1    GALX01005299    JAB63167.1    KQ971729    KYB24751.1    ABLF02014862    ABLF02014866    ABLF02061908    KQ973342    KXZ75569.1    ABLF02008933    ABLF02042518    ABLF02057746    ABLF02029306    ABLF02029314    ABLF02060138    ABLF02003961    ABLF02059872    GGMR01016114    MBY28733.1    GALX01005300    JAB63166.1    GGMS01004685    MBY73888.1    GGMS01000737    MBY69940.1    KK117880    KFM71667.1    GEZM01038405    JAV81653.1    ABLF02033757    GGMS01012005    MBY81208.1    GGMR01018716    MBY31335.1    GGMS01008766    MBY77969.1    GBBI01004571    JAC14141.1    GGMR01000676    MBY13295.1    GBBI01004395    JAC14317.1    GFTR01008038    JAW08388.1    AF012049    AAC24972.1    GGMS01002955    MBY72158.1    GGMS01006359    MBY75562.1    GGMS01017914    MBY87117.1    GGMR01004661    MBY17280.1    ABLF02020655    ABLF02039168    ABLF02061060    GEZM01053022    JAV74219.1    NEVH01006736    PNF36716.1    GFXV01006424    MBW18229.1    NEVH01002704    PNF41489.1    KK113014    KFM59099.1    KL813758    KFM83187.1    GGMR01003407    MBY16026.1    NEVH01000269    PNF43694.1    ABLF02008463    NEVH01020940    PNF20481.1    GBGD01000880    JAC88009.1    GGFJ01001857    MBW50998.1    GBGD01000799    JAC88090.1    GFXV01007093    MBW18898.1    GFXV01000774    MBW12579.1    NEVH01012089    PNF30491.1    ABLF02024246    GGFJ01001858    MBW50999.1    NEVH01007393    PNF35987.1    NWSH01000032    PCG80497.1    GBBI01001646    JAC17066.1    ABLF02034467    NEVH01017542    PNF24034.1    RPOV01000134    RPJ78669.1    NEVH01006721    PNF37225.1    NEVH01007578    PNF35646.1    LBMM01014395    KMQ85192.1    NEVH01026106    PNF14658.1    ABLF02021177    ABLF02027367    ABLF02066338    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    ABLF02008153    ABLF02008462    ABLF02008464    AY060438    AAL25477.1    NEVH01026386    PNF14434.1    GBBI01001570    JAC17142.1    GBYB01008290    JAG78057.1    PYGN01000192    PSN51582.1    NEVH01016302    PNF25823.1    NEVH01022639    PNF18527.1    GEZM01097906    JAV54051.1    GGMS01002992    MBY72195.1    GDHC01014349    JAQ04280.1    ABLF02037660    GGMR01014053    MBY26672.1    AF237761    AAF81411.1    NEVH01003017    PNF40781.1    JXUM01241784    KQ635293    KXJ62492.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    NEVH01007443    PNF35684.1    NEVH01021586    NEVH01006600    NEVH01002584    PNF19589.1    PNF37419.1    PNF41868.1    PCG80496.1    NEVH01018383    PNF23463.1    NEVH01010546    PNF32261.1    NEVH01020071    PNF21969.1    S59870    AAB26437.2    NEVH01023962    PNF17612.1    NEVH01005938    PNF38077.1    GGMS01017365    MBY86568.1    LBMM01010106    KMQ87671.1    NEVH01001355    PNF42855.1    KQ972067    KYB24656.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000054359    UP000235965    UP000218220    + More
UP000036403    UP000245037    UP000069940    UP000249989   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    K9N5J5    Q95SX7    Q9NBX4    + More

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF03372   Exo_endo_phos
PF07530   PRE_C2HC
PF10551   MULE
PF17919   RT_RNaseH_2
PF17921   Integrase_H2C2
PF00077   RVP
PF00665   rve
PF17917   RT_RNaseH

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR018289   MULE_transposase_dom       
IPR012337   RNaseH-like_sf       
IPR001969   Aspartic_peptidase_AS       
IPR001584   Integrase_cat-core       
IPR041577   RT_RNaseH_2       
IPR001995   Peptidase_A2_cat       
IPR041373   RT_RNaseH       
IPR018061   Retropepsins       
IPR041588   Integrase_H2C2       
IPR036397   RNaseH_sf       
IPR021109   Peptidase_aspartic_dom_sf       

SUPFAM

SSF56219   SSF56219        + More
SSF53098   SSF53098       
SSF50630   SSF50630       

Gene 3D

3.60.10.10     2.40.70.10     3.30.420.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   K9N5J5   A0A0N0PA09   A0A0N1PFV1   + More
O96546   O96544   A0A194Q1H8   A0A1Y1NA23   V5GNF3   A0A2S2PR14   V5GNJ2   A0A139WA11   X1WMU5   A0A139W8G9   X1WXU3   X1WLB2   J9KKL3   X1WWC4   A0A2S2PH29   V5I850   A0A2S2Q823   A0A2S2PX53   A0A087U2S8   A0A1Y1M7E9   J9KC83   A0A2S2QTZ8   A0A2S2PPK8   A0A2S2QJM7   A0A023EZE6   A0A2S2N814   A0A023EYS8   A0A224XF24   O76197   A0A2S2Q352   A0A2S2QEE0   A0A2S2RAN7   A0A2S2NJB5   J9LC15   A0A1Y1LKN6   A0A2J7R7D0   A0A2H8TWD9   A0A2J7RL12   A0A087T1W0   A0A087V0P8   A0A2S2NGV8   A0A2J7RS81   J9KCZ4   A0A2J7PVX3   A0A069DZC5   A0A2M4BDV6   A0A069DW01   A0A2H8U0H5   A0A2H8TES1   A0A2J7QPI2   J9M522   A0A2M4BD67   A0A2J7R579   A0A2A4K8E7   A0A023F6S4   X1WZH0   A0A2J7Q627   A0A3N5Z7I3   A0A2J7R8R8   A0A2J7R4B1   A0A0J7K4E0   A0A2J7PEB1   X1WN18   A0A0A9YJ00   X1WNI2   Q95SX7   A0A2J7PDM0   A0A023F7D1   A0A0C9RJA4   A0A2P8Z520   A0A2J7QB68   A0A2J7PQB5   A0A1Y1K0N4   A0A2S2Q383   A0A146LCK7   X1WTA1   A0A2S2PBB4   Q9NBX4   A0A2J7RIW7   A0A182GB02   A0A0A9YU04   A0A2J7R4B7   A0A2J7RM10   A0A2A4K918   A0A2J7Q4F7   A0A2J7QUJ9   A0A2J7Q059   Q07995   A0A2J7PMP6   A0A2J7RB54   A0A2S2R9D4   A0A0J7KBP6   A0A2J7RPU2   A0A139W9S2  

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0016021   GO:0006313   GO:0005634   GO:0015074   GO:0004190   GO:0003676  

Length:

515

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

15.5205

Exp number, first 60 AAs:

12.82806

Total prob of N-in:

0.44184

POSSIBLE N-term signal

sequence

outside

1  -  515

 

 

Pi

32.114018

Theta

45.556932

Tajima's D

2.966284

CLR

0.221209

CSRT

0.979301034948253

Interpretation

Uncertain