Gene

KWMTBOMO09839

Annotation

endonuclease-reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr16(-):10115098-10116462      View in EpiBrowser

Full name

Integrin beta       + More
Guanylate cyclase      

Location in the cell

Cytoplasmic   Reliability : 1.776 Nuclear   Reliability : 1.087

CDS

ATGTCAGTCCGAGTACAGGAGCATTGCACGAAGGAAATCCCTGTAAAGAGAGGAGTGAGACAGGGAGATGTGATATCTCCGAAACTGTTTATCACTGCTCTGGAGGATTCCTTCAAGCTTCTGGAATGGCAAGGACTTGGCATCAATATTAACGGCGAATACATCACTCATCTTCGGTTTGCCGATGACATCGTGGTCATGGCAGAGTCGCTGGAAGATTTAGGGCGTATGCTCGGTGACCTCAGTAGGGTTTCTCAACAAGTGGGTCTTAAAATGAACATGGACAAAACAAAAATCATGTACAATGTCCATGTTGCACCCACCATAGTTACTGTTGGGAGCTCTACTCTTGAAGTTGTTGACGAATATATATACCTAGGACAGGCAGTCCGATTAGCTAGGTCCAACTTTGAGAGAGAGGTCAGTAGACGGATCCAACTCGGCTGGGCAGCGTTCGGTAAACTGCACAACGTCTTCTCGTCCAAAATACCTCAGTGCCTTAAGACAAAGGTGTACAACCAATGTGTGTTACCAGTGATGACTTACGGCTCGGAGACGTGGTGCTTCACTAGGGATCTTTTTAGAAGGCTCAAAGTCGCGCAGCGAGCTATGGAGAGGGCTATGCTCGGCATTTCTCTACGTGATCGAATCTGA

Protein

MSVRVQEHCTKEIPVKRGVRQGDVISPKLFITALEDSFKLLEWQGLGININGEYITHLRFADDIVVMAESLEDLGRMLGDLSRVSQQVGLKMNMDKTKIMYNVHVAPTIVTVGSSTLEVVDEYIYLGQAVRLARSNFEREVSRRIQLGWAAFGKLHNVFSSKIPQCLKTKVYNQCVLPVMTYGSETWCFTRDLFRRLKVAQRAMERAMLGISLRDRI

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the integrin beta chain family.
Belongs to the ATP-dependent DNA ligase family.

Feature

chain  Integrin beta

Uniprot

D7F158   D7F159   A0A2W1BMB6   A4KWF4   A4KWF2   A4KWG0   + More
A0A3S2TAR4   D7F164   A0A437BHD1   A0A437AW45   D7F157   A0A3S2KX72   A0A3S2LUJ5   D7F165   S4NRD2   D7F166   D7F160   A0A023GMF8   A0A2G8KBI6   A0A1E1X2U1   A0A2G8JFM9   W4YXJ1   A0A437ARW6   A0A2G8KES6   A0A3S2TRE0   K7F154   A0A1E1XRS4   A0A2G8K4F2   A0A2W1BLC9   W4YXJ0   A0A2W1BSQ8   A0A2W1BDX2   A0A0K0FAW8   A0A3S2LNU0   A0A016UYJ1   A0A016S403   A0A016U784   A0A016WZF0   A0A016X056   A0A2H1VY30   A0A016SGC3   A0A069DX96   A0A016SX67   A0A016W591   D7F177   D7F176   A0A0N5C0B1   A0A2W1BCS2   A0A016TNH6   A0A016TNL1   A0A2W1B5F8   A0A016TNS4   A0A016TMT8   A0A023EWU8   A0A016U3R5   A0A023EXV2   A0A2H1VS24   A0A016T590   A0A016VEC1   A0A016VCD9   A0A0P4VWD0   A0A224XSN7   A0A016VBP7   A0A016VCU3   A0A016UL89   A0A016T7J7   A0A016TIA8   A0A016T8K4   A0A2W1BZV1   A0A3P6RMQ7   A0A016WEQ1   A0A016V6V0   A0A016SUK5   A0A016WA79   A0A016S795   A0A0B2VZ02   A0A016VVN3   A0A016S5B2   A0A016UMK7   A0A016T8K0   A0A016VV56   A0A016V7H3   A0A016RXU5   A0A090MSX2   A0A016RYK0   H3E3P6   A0A0R3Q573   A0A2H2JCJ4   A0A016WPY4   A0A1I7Z5Z9   A0A016S1D2   D7F178   A0A016UTS3   A0A016UWI5  

EC Number

4.6.1.2

Pubmed

20470440    28756777    17360547    23622113    29023486    28503490    + More
17381049    29209593    25730766    26334808    25474469    27129103    18806794    26392177   

EMBL

FJ265543    ADI61811.1    FJ265544    ADI61812.1    KZ150072    PZC74016.1    + More
EF113399    EF113400    ABO45233.1    EF113398    EF113401    ABO45231.1    EF113402    ABO45239.1    RSAL01002362    RVE40503.1    FJ265549    ADI61817.1    RSAL01000057    RVE49824.1    RSAL01000344    RVE42347.1    FJ265542    ADI61810.1    RSAL01002130    RVE40575.1    RSAL01000007    RVE54059.1    FJ265550    ADI61818.1    GAIX01012906    JAA79654.1    FJ265551    ADI61819.1    FJ265545    ADI61813.1    GBBM01001358    JAC34060.1    MRZV01000717    PIK45367.1    GFAC01005640    JAT93548.1    MRZV01002136    PIK34564.1    AAGJ04144474    RSAL01003575    RVE40262.1    MRZV01000640    PIK46507.1    RSAL01000016    RVE53061.1    AGCU01063447    GFAA01001426    JAU02009.1    MRZV01000899    PIK42833.1    KZ149985    PZC75698.1    AAGJ04050748    KZ149912    PZC78089.1    KZ150108    PZC73382.1    RSAL01002495    RVE40475.1    JARK01001359    EYC20046.1    JARK01001639    EYB85201.1    JARK01001389    EYC11015.1    JARK01000055    EYC44622.1    EYC44623.1    ODYU01004982    SOQ45402.1    JARK01001568    EYB89432.1    GBGD01000453    JAC88436.1    JARK01001500    JARK01001343    EYB95040.1    EYC28825.1    JARK01000807    EYC34984.1    FJ265562    ADI61830.1    FJ265561    ADI61829.1    KZ150485    PZC70710.1    JARK01001424    EYC04315.1    EYC04316.1    KZ150317    PZC71439.1    EYC04317.1    EYC04314.1    GBBI01004877    JAC13835.1    JARK01001396    EYC09581.1    GBBI01004876    JAC13836.1    ODYU01004088    SOQ43598.1    JARK01001473    EYB97806.1    JARK01001348    EYC25048.1    EYC25050.1    GDKW01001596    JAI54999.1    GFTR01005437    JAW10989.1    EYC25049.1    EYC25046.1    JARK01001372    EYC15592.1    JARK01001736    JARK01001462    JARK01001379    JARK01001338    EYB80775.1    EYB98943.1    EYC13646.1    EYC33347.1    JARK01001434    EYC02684.1    EYB98997.1    KZ149907    PZC78256.1    UYRV01017460    VDK63226.1    JARK01000347    EYC38051.1    JARK01001351    EYC23394.1    JARK01001512    EYB94036.1    JARK01000460    EYC36749.1    JARK01001621    EYB86109.1    JPKZ01000640    KHN86200.1    JARK01001340    EYC30828.1    JARK01001626    EYB85833.1    JARK01001370    EYC16151.1    EYB98944.1    EYC31295.1    EYC23395.1    JARK01001677    EYB83168.1    LN609407    CEF61413.1    EYB83167.1    UZAG01000503    VDO08661.1    JARK01000173    EYC41342.1    JARK01001655    EYB84321.1    FJ265563    ADI61831.1    JARK01001362    EYC18844.1    EYC18843.1   

Proteomes

UP000283053    UP000230750    UP000007110    UP000007267    UP000035680    UP000024635    + More
UP000046392    UP000031036    UP000005239    UP000050602    UP000005237    UP000095287   

PRIDE

D7F158    D7F159    D7F164    D7F157    D7F165    D7F166    + More
D7F160    D7F177    D7F176    D7F178   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF00362   Integrin_beta
PF01826   TIL
PF11411   DNA_ligase_IV
PF04675   DNA_ligase_A_N
PF04679   DNA_ligase_A_C
PF01068   DNA_ligase_A_M
PF13855   LRR_8
PF00071   Ras
PF01549   ShK
PF01094   ANF_receptor
PF07714   Pkinase_Tyr
PF00211   Guanylate_cyc

Interpro

IPR005135   Endo/exonuclease/phosphatase        + More
IPR036691   Endo/exonu/phosph_ase_sf       
IPR000477   RT_dom       
IPR032695   Integrin_dom_sf       
IPR036465   vWFA_dom_sf       
IPR015812   Integrin_bsu       
IPR002035   VWF_A       
IPR002369   Integrin_bsu_VWA       
IPR011993   PH-like_dom_sf       
IPR036084   Ser_inhib-like_sf       
IPR002919   TIL_dom       
IPR001357   BRCT_dom       
IPR036420   BRCT_dom_sf       
IPR012340   NA-bd_OB-fold       
IPR016059   DNA_ligase_ATP-dep_CS       
IPR012310   DNA_ligase_ATP-dep_cent       
IPR021536   DNA_ligase_IV_dom       
IPR029710   LIG4       
IPR000977   DNA_ligase_ATP-dep       
IPR012308   DNA_ligase_ATP-dep_N       
IPR036599   DNA_ligase_N_sf       
IPR012309   DNA_ligase_ATP-dep_C       
IPR032675   LRR_dom_sf       
IPR001611   Leu-rich_rpt       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR005225   Small_GTP-bd_dom       
IPR025662   Sigma_54_int_dom_ATP-bd_1       
IPR027417   P-loop_NTPase       
IPR001806   Small_GTPase       
IPR003582   ShKT_dom       
IPR001828   ANF_lig-bd_rcpt       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR001170   ANPR/GUC       
IPR001054   A/G_cyclase       
IPR028082   Peripla_BP_I       
IPR000719   Prot_kinase_dom       
IPR029787   Nucleotide_cyclase       
IPR029052   Metallo-depent_PP-like       

SUPFAM

SSF56219   SSF56219        + More
SSF53300   SSF53300       
SSF69179   SSF69179       
SSF57567   SSF57567       
SSF52113   SSF52113       
SSF50249   SSF50249       
SSF52540   SSF52540       
SSF53822   SSF53822       
SSF55073   SSF55073       
SSF56112   SSF56112       

Gene 3D

3.60.10.10     3.40.50.410     2.30.29.30     1.10.3260.10     3.40.50.10190     3.80.10.10     3.30.70.1230     3.60.21.10    

ProteinModelPortal

D7F158   D7F159   A0A2W1BMB6   A4KWF4   A4KWF2   A4KWG0   + More
A0A3S2TAR4   D7F164   A0A437BHD1   A0A437AW45   D7F157   A0A3S2KX72   A0A3S2LUJ5   D7F165   S4NRD2   D7F166   D7F160   A0A023GMF8   A0A2G8KBI6   A0A1E1X2U1   A0A2G8JFM9   W4YXJ1   A0A437ARW6   A0A2G8KES6   A0A3S2TRE0   K7F154   A0A1E1XRS4   A0A2G8K4F2   A0A2W1BLC9   W4YXJ0   A0A2W1BSQ8   A0A2W1BDX2   A0A0K0FAW8   A0A3S2LNU0   A0A016UYJ1   A0A016S403   A0A016U784   A0A016WZF0   A0A016X056   A0A2H1VY30   A0A016SGC3   A0A069DX96   A0A016SX67   A0A016W591   D7F177   D7F176   A0A0N5C0B1   A0A2W1BCS2   A0A016TNH6   A0A016TNL1   A0A2W1B5F8   A0A016TNS4   A0A016TMT8   A0A023EWU8   A0A016U3R5   A0A023EXV2   A0A2H1VS24   A0A016T590   A0A016VEC1   A0A016VCD9   A0A0P4VWD0   A0A224XSN7   A0A016VBP7   A0A016VCU3   A0A016UL89   A0A016T7J7   A0A016TIA8   A0A016T8K4   A0A2W1BZV1   A0A3P6RMQ7   A0A016WEQ1   A0A016V6V0   A0A016SUK5   A0A016WA79   A0A016S795   A0A0B2VZ02   A0A016VVN3   A0A016S5B2   A0A016UMK7   A0A016T8K0   A0A016VV56   A0A016V7H3   A0A016RXU5   A0A090MSX2   A0A016RYK0   H3E3P6   A0A0R3Q573   A0A2H2JCJ4   A0A016WPY4   A0A1I7Z5Z9   A0A016S1D2   D7F178   A0A016UTS3   A0A016UWI5  

PDB

5HHL     E-value=0.000468875,     Score=100

KEGG

101744003    no KO assigned | (RefSeq) uncharacterized LOC101744003

GO

GO:0004519   GO:0003964   GO:0005524   GO:0004672   GO:0004383   GO:0016021   GO:0035556  

PANTHER

PTHR10082   PTHR45997:SF1  

Subcellular location

Membrane  

Length:

217

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.41737

Exp number, first 60 AAs:

0.00094

Total prob of N-in:

0.28092

outside

1  -  217

 

 

Pi

209.591113

Theta

133.543426

Tajima's D

2.9978

CLR

13.956336

CSRT

0.980150992450378

Interpretation

Uncertain