Gene

KWMTBOMO09836  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013130

Annotation

PREDICTED:_glucosylceramidase-like_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr16(+):10041053-10043446      View in EpiBrowser

Full name

Glucosylceramidase      

Location in the cell

Cytoplasmic   Reliability : 1.238 Extracellular   Reliability : 1.211

CDS

ATGGACTTGAACTATAACTACACCGGTTGGATAGATTGGAATTTGTGTCTCGATACTGAAGGTGGTCCAAATTGGGTCCAAAATTATGTCGACTCGCCGATTGTTGTCGACGCGGAGGCAGGTGTCTTCTACAAGCAGCCGATATTCTATGCTATGGGTCATTTTTCTAAGTTCATCCCTAGAGGCTCGAGGAGGATCAAGTCTACGGAGAAATATAACTGTTCAAACGCTTTGAAACATGTAGCCTTTTTGACACCAGAAAATACTATCGTCGTGGTTCTTCTTAACGAAGATAACAAAGACAGAGTTATTCGTTTGAAGTTCGGTGACAATCAAGCGAAGGTGCTTGTCGAGGGAAAGTCTATAATCACCGTCGAGTTCAACAACGAAGTTCAAGACGATTCTTGCGACTGTGATTGA

Protein

MDLNYNYTGWIDWNLCLDTEGGPNWVQNYVDSPIVVDAEAGVFYKQPIFYAMGHFSKFIPRGSRRIKSTEKYNCSNALKHVAFLTPENTIVVVLLNEDNKDRVIRLKFGDNQAKVLVEGKSIITVEFNNEVQDDSCDCD

Catalytic Activity

a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose

Similarity

Belongs to the glycosyl hydrolase 30 family.

Feature

chain  Glucosylceramidase

Uniprot

H9JUB7   H9JUB6   A0A0N1INL2   A0A2A4K975   A0A212EPK9   A0A437ARV3   + More
A0A0N1IF15   A0A2A4K8P8   A0A2H1WWW7   A0A437BUD8   A0A1W1EGM7   A0A212F349   A0A212F293   A0A2H1VST3   A0A2H1VUS0   A0A3M0J565   A0A131Z3G7   A0A212F254   L7M0B5   A0A2H1VG50   H3G7I4   A0A452ICC8   A0A023GIV4   L7M0C6   A0A131YKA6   A0A3L8RV84   A0A1V4KDC5   A0A224YYV0   A0A224YXV5   G4ZEY4   A0A329SI21   A0A093BHB6   A0A218UMU9   A0A452ICI5   A0A437B0B5   A0A2I0LM54   A0A1D5NWE6   A0A3Q2U6X4   W2QN93   V9FRQ0   W2XM40   A0A081AVG3   W2LSY8   A0A0W8D122   A0A131YJ49   A0A2G9U5T9   W2ZX75   A0A093GAN8   A0A225WY05   U3JJS0   A0A3L8RW53   A0A091I5V7   A0A3R7MN95   A0A293MAW8   A0A1U7SIA2   A0A329T1H5   A0A452ICH6   A0A081ANK4   A0A452ID18   V9FJP4   W2XFZ2   W2QJE5   W2ZQ36   W2HAK1   U3JJS6   A0A421G9R3   A0A3Q0HD48   A0A3Q0DMP0   A0A091FYT6   A0A3M0IZB8   A0A1U7SVT9   J9L5B0   A0A2P4WZX2   A0A1E1X9A0   A0A3Q0HA13   A0A1U7T338   A0A3Q0HD38   A0A293N7G8   W2HHH0   A0A151N939   A0A3R7H2D6   W2JP47   A0A0C9QXG4   A0A0Q3QSH3   A0A218UMY8   A0A099ZCW2  

EC Number

3.2.1.45

Pubmed

19121390    26354079    22118469    28680679    26830274    25576852    + More
16946064    28562605    30282656    28797301    23371554    15592404    28186564    28503490    22293439   

EMBL

BABH01038531    BABH01038532    BABH01038533    BABH01038534    BABH01038539    BABH01038540    + More
BABH01038541    KQ461178    KPJ07772.1    NWSH01000035    PCG80448.1    AGBW02013448    OWR43423.1    RSAL01003486    RVE40276.1    KPJ07773.1    PCG80449.1    ODYU01011672    SOQ57565.1    RSAL01000008    RVE53975.1    LT635665    SGZ49395.1    AGBW02010629    OWR48154.1    AGBW02010783    OWR47849.1    ODYU01004232    SOQ43893.1    ODYU01004571    SOQ44585.1    QRBI01000202    RMB93899.1    GEDV01003886    JAP84671.1    OWR47828.1    GACK01007727    JAA57307.1    ODYU01002190    SOQ39362.1    DS566059    GBBM01001526    JAC33892.1    GACK01007712    JAA57322.1    GEDV01009569    JAP78988.1    QUSF01000198    RLV87492.1    LSYS01003627    OPJ82428.1    GFPF01008008    MAA19154.1    GFPF01008007    MAA19153.1    JH159154    EGZ17896.1    MJFZ01000176    RAW35212.1    KN125716    KFU83958.1    MUZQ01000219    OWK55107.1    RSAL01000232    RVE43819.1    AKCR02000200    PKK18507.1    AADN05000466    KI669572    ETN14662.1    ANIZ01000561    ETI54139.1    ANIX01000668    ETP23960.1    ANJA01000623    ETO82874.1    KI678010    KI691249    ETM00502.1    ETM53704.1    LNFP01001456    LNFO01001593    KUF86242.1    KUF90004.1    GEDV01009570    JAP78987.1    KZ349327    PIO65072.1    ANIY01000684    ETP51967.1    KL215229    KFV63809.1    NBNE01000176    OWZ21918.1    AGTO01022043    RLV87493.1    KL218155    KFP02780.1    MAYM02001651    RLN14102.1    GFWV01011406    MAA36135.1    MJFZ01000012    RAW42725.1    ANJA01000988    ETO80465.1    ANIZ01000889    ETI51715.1    ANIX01001073    ETP21412.1    KI669577    ETN12365.1    ANIY01001102    ETP49403.1    KI685308    KI671854    KI678592    KI691839    ETK91605.1    ETL45015.1    ETL98169.1    ETM51333.1    MBAD02000201    RLN70671.1    KL447511    KFO74306.1    RMB93898.1    ABLF02008893    NCKW01020142    POM58843.1    GFAC01003537    JAT95651.1    GFWV01022833    MAA47560.1    KI684753    ETK94015.1    AKHW03003703    KYO33342.1    MBAD02001844    RLN51535.1    KI671251    ETL47408.1    GBYB01005352    JAG75119.1    LMAW01002883    KQK76089.1    OWK55104.1    KL892965    KGL80274.1   

Proteomes

UP000005204    UP000053240    UP000218220    UP000007151    UP000283053    UP000269221    + More
UP000005238    UP000291020    UP000276834    UP000190648    UP000002640    UP000251314    UP000197619    UP000053872    UP000000539    UP000018817    UP000018721    UP000018958    UP000028582    UP000054423    UP000054532    UP000052943    UP000018948    UP000053875    UP000198211    UP000016665    UP000054308    UP000285883    UP000189705    UP000053236    UP000053864    UP000284657    UP000189704    UP000053760    UP000007819    UP000050525    UP000051836    UP000053641   

PRIDE

H9JUB7    H9JUB6   

Pfam

PF17189   Glyco_hydro_30C        + More
PF02055   Glyco_hydro_30

Interpro

IPR001139   Glyco_hydro_30        + More
IPR017853   Glycoside_hydrolase_SF       
IPR013780   Glyco_hydro_b       
IPR033453   Glyco_hydro_30_TIM-barrel       
IPR033452   GH30_C       

SUPFAM

SSF51445   SSF51445       

Gene 3D

2.60.40.1180    

ProteinModelPortal

H9JUB7   H9JUB6   A0A0N1INL2   A0A2A4K975   A0A212EPK9   A0A437ARV3   + More
A0A0N1IF15   A0A2A4K8P8   A0A2H1WWW7   A0A437BUD8   A0A1W1EGM7   A0A212F349   A0A212F293   A0A2H1VST3   A0A2H1VUS0   A0A3M0J565   A0A131Z3G7   A0A212F254   L7M0B5   A0A2H1VG50   H3G7I4   A0A452ICC8   A0A023GIV4   L7M0C6   A0A131YKA6   A0A3L8RV84   A0A1V4KDC5   A0A224YYV0   A0A224YXV5   G4ZEY4   A0A329SI21   A0A093BHB6   A0A218UMU9   A0A452ICI5   A0A437B0B5   A0A2I0LM54   A0A1D5NWE6   A0A3Q2U6X4   W2QN93   V9FRQ0   W2XM40   A0A081AVG3   W2LSY8   A0A0W8D122   A0A131YJ49   A0A2G9U5T9   W2ZX75   A0A093GAN8   A0A225WY05   U3JJS0   A0A3L8RW53   A0A091I5V7   A0A3R7MN95   A0A293MAW8   A0A1U7SIA2   A0A329T1H5   A0A452ICH6   A0A081ANK4   A0A452ID18   V9FJP4   W2XFZ2   W2QJE5   W2ZQ36   W2HAK1   U3JJS6   A0A421G9R3   A0A3Q0HD48   A0A3Q0DMP0   A0A091FYT6   A0A3M0IZB8   A0A1U7SVT9   J9L5B0   A0A2P4WZX2   A0A1E1X9A0   A0A3Q0HA13   A0A1U7T338   A0A3Q0HD38   A0A293N7G8   W2HHH0   A0A151N939   A0A3R7H2D6   W2JP47   A0A0C9QXG4   A0A0Q3QSH3   A0A218UMY8   A0A099ZCW2  

PDB

6Q6N     E-value=1.08978e-28,     Score=308

KEGG

101742496    K01201 glucosylceramidase [EC:3.2.1.45] | (RefSeq) glucosylceramidase-like

PATHWAY

00511    Other glycan degradation - Bombyx mori (domestic silkworm)
00600    Sphingolipid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0006665   GO:0004348   GO:0006680   GO:0016787   GO:0030259   GO:0071356   GO:0006914   GO:0023021   GO:1904457   GO:0005124   GO:0046527   GO:0032715   GO:0050295   GO:0005765   GO:0043243   GO:1903061   GO:0046512   GO:0007040   GO:0032463   GO:0008203   GO:0043407   GO:1901215   GO:0032006   GO:0046513   GO:1903052   GO:0035307   GO:0005975   GO:0008270   GO:0005488   GO:0008565   GO:0015031   GO:0009258   GO:0016155   GO:0003824  

PANTHER

PTHR11069  

Length:

139

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.15031

Exp number, first 60 AAs:

0.10318

Total prob of N-in:

0.26268

outside

1  -  139

 

 

Pi

134.30763

Theta

124.631715

Tajima's D

0.056082

CLR

12.617959

CSRT

0.386530673466327

Interpretation

Uncertain