Gene

KWMTBOMO09834

Pre Gene Modal

BGIBMGA013130

Annotation

glucosylceramidase_[Papilio_xuthus]

Location

Bomo_Chr16(+):10027833-10030712      View in EpiBrowser

Full name

Glucosylceramidase      

Location in the cell

PlasmaMembrane   Reliability : 1.856

CDS

ATGATTAGAACACCGATAGGAGGTAGTGATTTTTCAAGCCGCGCATACACTCTGAACGACTATCCTCTTGATGATAAGGAACTCGGAAACTTCAGTTTAAGTTACGAAGATTACAATTATAAGTTGCCAATGATAAAAGCTTGCCTAGCTGCAGCGAGCTCGCAGGTCTTCATGGTTGGAACAACGTGGTCACCTCCAGCGTGGATGAAGACTTCCGGATCATTAACGGGCGTCGGTTATCTTAAGGAAGAGTATTTTGAGGCGTATGCTAATTACCACAAGAAGTTCCTAGAAGAATACAAAAGGAACAACATTTCTTTTTGGGCTATAACGACCACTAATGAACCTTTGAATGGTGTTGTAGATCTACCGGACTTCAATTGTCTTGGTTGGACAATCGAGGGGATGGTGAGTGTAATGTCTTTTGTCGAGTTGGATTCTAAGCCCCAACGTCCCAGTTTTACAGTACAACGAATGCTCTGCTGCTAA

Protein

MIRTPIGGSDFSSRAYTLNDYPLDDKELGNFSLSYEDYNYKLPMIKACLAAASSQVFMVGTTWSPPAWMKTSGSLTGVGYLKEEYFEAYANYHKKFLEEYKRNNISFWAITTTNEPLNGVVDLPDFNCLGWTIEGMVSVMSFVELDSKPQRPSFTVQRMLCC

Catalytic Activity

a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose

Similarity

Belongs to the glycosyl hydrolase 30 family.

Feature

chain  Glucosylceramidase

Uniprot

H9JUB7   I4DLH0   A0A212FNA8   A0A1W1EGM7   H9JUB6   A0A212F248   + More
A0A194PPY1   A0A3S2NLJ3   A0A2H1VG50   A0A2H1VUS0   A0A194Q614   A0A0N1IF15   A0A0L7L523   A0A2H1WWW7   A0A2A4K8P8   A0A437B0B5   A0A2A4K975   A0A2H1VST3   A0A437BUD8   A0A2H1X380   J9K5F8   A0A3Q0JJ39   A0A0L7QMS7   E9HE79   A0A0P5V3Y6   A0A154P4F4   A0A0P5V259   A0A0P5V115   A0A0P5UAZ3   A0A0P5UEK4   A0A0P5MIQ6   T1L0X2   A0A212F254   A0A0P5UKE0   A0A0N8CP26   A0A0P5XZL7   D6WRN0   A0A0N8C3M9   A0A0P5VAG5   A0A0P5D4A0   A0A0P6HWY3   A0A0P5BCG5   A0A0P5BE18   A0A0N8BXP2   A0A0P5YAM8   A0A067QM95   A0A0P6CTA3   S4RMS8   A0A1B6LUZ4   A0A1D2MAR5   A0A0P5EBB8   A0A2J7R6I8   A0A1B6J3H7   A0A2J7R6J3   T1JW72   A0A2J7R6J1   A0A0P5E6V6   C3YQ03   A0A1B6FTD6   A0A0P5F794   A0A0N8EC25   A0A1B6IGC1   A0A1B6K1N7   A0A0P5UX07   A0A0P5YE76   A0A423SIH3   A0A0P4Y4V0   A0A0P6GJR3   A0A0N8DE38   A0A0P5XUP8   A0A0P5Y055   A0A0P5X813   A0A0P5YNS9   A0A139WEE1   A0A0P5V575   A0A0P5Y2L0   A0A0P5XL26   A0A162QRA1   A0A0N8A576   A0A0P5Z7Y2   A0A1Y3AW29   A0A0P5BMC7   A0A0P5L6K4   A0A0P5V0B5   A0A131Z9I7   A0A0P5WP50   A0A0P5F4K4   A0A0P5UYZ4   A0A0P5MXS5   A0A0L8GBA3   A0A0P6E3A7   A0A088APM4   A0A0P5E3J3   V9IBT9   A0A0P5GMD5   A0A226EKU6   A0A0P6HUV1   A0A0P6B2C4   A0A1D5NWE6   A0A224YYV0  

EC Number

3.2.1.45

Pubmed

19121390    22651552    22118469    28680679    26354079    26227816    + More
21292972    18362917    19820115    24845553    27289101    18563158    26830274    15592404    28797301   

EMBL

BABH01038531    BABH01038532    BABH01038533    BABH01038534    AK402138    BAM18760.1    + More
AGBW02006772    OWR55189.1    LT635665    SGZ49395.1    BABH01038539    BABH01038540    BABH01038541    AGBW02010783    OWR47794.1    KQ459602    KPI93190.1    RSAL01000008    RVE53974.1    ODYU01002190    SOQ39362.1    ODYU01004571    SOQ44585.1    KQ459439    KPJ00977.1    KQ461178    KPJ07773.1    JTDY01002868    KOB70572.1    ODYU01011672    SOQ57565.1    NWSH01000035    PCG80449.1    RSAL01000232    RVE43819.1    PCG80448.1    ODYU01004232    SOQ43893.1    RVE53975.1    ODYU01013051    SOQ59702.1    ABLF02017156    ABLF02017157    ABLF02017158    ABLF02017160    ABLF02043031    ABLF02044170    KQ414868    KOC59952.1    GL732627    EFX69969.1    GDIP01105547    JAL98167.1    KQ434814    KZC06829.1    GDIP01105549    JAL98165.1    GDIP01105548    JAL98166.1    GDIP01115596    JAL88118.1    GDIP01114152    JAL89562.1    GDIQ01166874    JAK84851.1    CAEY01000873    OWR47828.1    GDIP01111638    JAL92076.1    GDIP01112839    JAL90875.1    GDIP01066853    JAM36862.1    KQ971354    EFA07058.2    GDIQ01118027    JAL33699.1    GDIP01102691    JAM01024.1    GDIP01163230    LRGB01000311    JAJ60172.1    KZS19886.1    GDIQ01028607    JAN66130.1    GDIP01186374    JAJ37028.1    GDIP01190080    JAJ33322.1    GDIQ01134723    JAL17003.1    GDIP01074304    JAM29411.1    KK853153    KDR10552.1    GDIP01009481    JAM94234.1    GEBQ01024969    GEBQ01012479    JAT15008.1    JAT27498.1    LJIJ01002183    ODM90073.1    GDIP01148941    JAJ74461.1    NEVH01006756    PNF36451.1    GECU01013983    JAS93723.1    PNF36457.1    CAEY01000807    PNF36452.1    GDIP01147340    JAJ76062.1    GG666539    EEN57641.1    GECZ01016297    JAS53472.1    GDIQ01261732    JAJ89992.1    GDIQ01041468    JAN53269.1    GECU01021735    JAS85971.1    GECU01002337    JAT05370.1    GDIP01107443    JAL96271.1    GDIP01073106    JAM30609.1    QCYY01003347    ROT63991.1    GDIP01234780    JAI88621.1    GDIQ01034555    JAN60182.1    GDIP01042743    JAM60972.1    GDIP01067454    JAM36261.1    GDIP01065954    JAM37761.1    GDIP01077038    JAM26677.1    GDIP01056052    JAM47663.1    KYB26348.1    GDIP01104846    JAL98868.1    GDIP01077037    JAM26678.1    GDIP01070494    JAM33221.1    KZS19887.1    GDIP01181329    JAJ42073.1    GDIP01060297    JAM43418.1    MUJZ01055050    OTF72692.1    GDIP01182978    JAJ40424.1    GDIQ01199303    JAK52422.1    GDIP01107444    JAL96270.1    GEDV01001092    JAP87465.1    GDIP01083544    JAM20171.1    GDIQ01263085    JAJ88639.1    GDIP01107445    JAL96269.1    GDIQ01149727    JAL01999.1    KQ422986    KOF73820.1    GDIQ01068405    JAN26332.1    GDIP01147339    JAJ76063.1    JR037481    JR037482    AEY57789.1    AEY57790.1    GDIQ01261484    JAJ90240.1    LNIX01000003    OXA58323.1    GDIQ01038503    JAN56234.1    GDIP01023117    JAM80598.1    AADN05000466    GFPF01008008    MAA19154.1   

Proteomes

UP000005204    UP000007151    UP000053268    UP000283053    UP000053240    UP000037510    + More
UP000218220    UP000007819    UP000079169    UP000053825    UP000000305    UP000076502    UP000015104    UP000007266    UP000076858    UP000027135    UP000245300    UP000094527    UP000235965    UP000001554    UP000283509    UP000053454    UP000005203    UP000198287    UP000000539   

PRIDE

H9JUB7    H9JUB6   

Pfam

PF17189   Glyco_hydro_30C        + More
PF02055   Glyco_hydro_30
PF01285   TEA
PF17725   YBD

Interpro

IPR001139   Glyco_hydro_30        + More
IPR017853   Glycoside_hydrolase_SF       
IPR013780   Glyco_hydro_b       
IPR033453   Glyco_hydro_30_TIM-barrel       
IPR033452   GH30_C       
IPR000818   TEA/ATTS_dom       
IPR038096   TEA/ATTS_sf       
IPR041086   YBD       

SUPFAM

SSF51445   SSF51445       

Gene 3D

2.60.40.1180     1.10.10.1610    

ProteinModelPortal

H9JUB7   I4DLH0   A0A212FNA8   A0A1W1EGM7   H9JUB6   A0A212F248   + More
A0A194PPY1   A0A3S2NLJ3   A0A2H1VG50   A0A2H1VUS0   A0A194Q614   A0A0N1IF15   A0A0L7L523   A0A2H1WWW7   A0A2A4K8P8   A0A437B0B5   A0A2A4K975   A0A2H1VST3   A0A437BUD8   A0A2H1X380   J9K5F8   A0A3Q0JJ39   A0A0L7QMS7   E9HE79   A0A0P5V3Y6   A0A154P4F4   A0A0P5V259   A0A0P5V115   A0A0P5UAZ3   A0A0P5UEK4   A0A0P5MIQ6   T1L0X2   A0A212F254   A0A0P5UKE0   A0A0N8CP26   A0A0P5XZL7   D6WRN0   A0A0N8C3M9   A0A0P5VAG5   A0A0P5D4A0   A0A0P6HWY3   A0A0P5BCG5   A0A0P5BE18   A0A0N8BXP2   A0A0P5YAM8   A0A067QM95   A0A0P6CTA3   S4RMS8   A0A1B6LUZ4   A0A1D2MAR5   A0A0P5EBB8   A0A2J7R6I8   A0A1B6J3H7   A0A2J7R6J3   T1JW72   A0A2J7R6J1   A0A0P5E6V6   C3YQ03   A0A1B6FTD6   A0A0P5F794   A0A0N8EC25   A0A1B6IGC1   A0A1B6K1N7   A0A0P5UX07   A0A0P5YE76   A0A423SIH3   A0A0P4Y4V0   A0A0P6GJR3   A0A0N8DE38   A0A0P5XUP8   A0A0P5Y055   A0A0P5X813   A0A0P5YNS9   A0A139WEE1   A0A0P5V575   A0A0P5Y2L0   A0A0P5XL26   A0A162QRA1   A0A0N8A576   A0A0P5Z7Y2   A0A1Y3AW29   A0A0P5BMC7   A0A0P5L6K4   A0A0P5V0B5   A0A131Z9I7   A0A0P5WP50   A0A0P5F4K4   A0A0P5UYZ4   A0A0P5MXS5   A0A0L8GBA3   A0A0P6E3A7   A0A088APM4   A0A0P5E3J3   V9IBT9   A0A0P5GMD5   A0A226EKU6   A0A0P6HUV1   A0A0P6B2C4   A0A1D5NWE6   A0A224YYV0  

PDB

2XWE     E-value=3.1821e-25,     Score=280

KEGG

101742496    K01201 glucosylceramidase [EC:3.2.1.45] | (RefSeq) glucosylceramidase-like

GO

GO:0006665   GO:0004348   GO:0003700   GO:0006680   GO:0016787   GO:0016021   GO:0005975   GO:0008270   GO:0005488   GO:0008565   GO:0015031   GO:0009258   GO:0016155   GO:0003824  

PANTHER

PTHR11069  

Length:

162

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.31701

Exp number, first 60 AAs:

0.215

Total prob of N-in:

0.11300

outside

1  -  162

 

 

Pi

243.669468

Theta

162.380857

Tajima's D

1.638119

CLR

0.05787

CSRT

0.823558822058897

Interpretation

Uncertain