Gene

KWMTBOMO09811  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013142

Annotation

PREDICTED:_oxysterol-binding_protein_1_[Papilio_polytes]

Location

Bomo_Chr16(-):9708510-9734888      View in EpiBrowser

Full name

Oxysterol-binding protein      

Location in the cell

Cytoplasmic   Reliability : 1.513

CDS

ATGTCTGAAGCAATTGTGCCTAAAGGTCAACCGATACCCGGGGATCCTGAAAAAAAAGGATGGCTTTTCAAATGGACGAATTACCTAAAAGGATATCAACGAAGGTGGTTCGTGTTGTCCAACGGATTATTATCCTACTACAGGAACCAAGCAGAAATGGCGCATACGTGTAGAGGAACTATTTCACTGCTCGGTGCTCTTATTCACACTGCTGATTCATGTACTTTTGTCATCAGCAATGGTGGCACACAGACATTCTACATTAAAGCTCATGATGAAGTAGAACGTCAGAGTTGGGTTACAGCCCTAGAATTGGCCAAGGCTAAAGCTATTCGAGCTCAAGAATCAGACGATGATGAAGACCAGGTGGCATCTGGAGCAGTAGTAATTGGTGGGGCTGGTGAAGGTGAAGGAGAAGACACTGGCGGCATTGCAAGAGAACTGGCAGCAAGATTTCATGACCTGCGTACCTGTTCAGAATTAGTAGCAAGACATGGAACAGCACTACAGAGATCACTTGTTGACTTGGAAATACCACCTTCGGATACAACGAAGCAAGTTTCCGAACGAGCGACACTCTTTAGAATATCCTGCAATGCAATGATGAATGCTTGTTCTGAGTTTATGAGCGCAGCAGCCGGATCAAGCGCACGACTTTCGCGAGCTTTGCAACACGAGCGAGAACAGAAGCTCCGTCTACAGGAGGTGGTTGAACAACTCGCTAGACAACATGATACGCTCGAAAAGACGGTCACGGCACGCTCCACCCCGCACACAGGTGGTAACGGGACAACTCAAGGCAACGAAACTGAGGATGAAGACCATGAATTCTTTGACGCAGTGGAGGAGGGCATCTCAACCAACATGGATGATAAGACTTCATTTGTAATTAAAGTACCAGTTAATAGAAAAAACAAAGTGAAGGACGGTGAAAGTTCGGATGAATCAGAAGGTGAAACAGTGACAGAAACACAACAGGTGATATTTGTGGAGGATAAGGAGCGAGCGGAGAGCGCGATGGGAGGCGCCGACGGAAGCACCACACCGTCGCTTCCGGCCAAAGACACCGACATTGTCGTCTGGGAGCTGTCGAAGATCCCTATCCCGGTGAACTTCAGCGAGCCGCTGTCGATGCTGCAGCGGCTGACGGAGGACTACGAGTACTCGTCGGTGCTGGACCAGGCCGCCAAGTTCGATGACCCCGCGCAGCAACTCGCCTACGTCGCCGCATTCACAGTCTCCTCGTACGCGACCACCGCGTGCCGGACAAACAAACCGTTCAATCCTCTGCTCGGCGAGACGTTCGAATGCGACCGCATGGCCGACCTCGGCTGGCGAGCCATCTCCGAACAGGTGTCGCATCACCCGCCGATGGTGGCGCAGTTCTGCGAGGGCACGTCGGGCTGGCAGTGCTGGCAGGAGTTCACCATGACCACCAAGTTCCGGGGGAAGTACCTCCAGATCATACCGCTCGGAGCCGCCTCCGCCAAGTTCCTCGCGCACGGAAACAAGTACACCTGGAGGAAGGTGACCACCACCGTCCACAATATCATTGTGGGCAAGCTGTGGGTCGATAACCACGGCGACATGGACATCGTGGGCGACGCCGGCCCGGCTACTGGGTACGTCGCGCACCTCAAGTACCTGCCCTACGGGTACTTCAGCAAAGACACGCAACGAAAAGTGACGGGCGTTGTCAAGGATCCCAACGGCGTGCCGAGGTACGTGCTACAAGGTCACTGGGACAGCCGCGTGGAGGTGGCCCCCGTCACGAGCACGTCGGCCGACAACTCCGTCTGCAAGACCGGCAAGTTCGTGACGGCGTGGCAGCGCGTGGCCGCCCCGCCCGACTCCGACAAGTGGTACAACTTCACCGTGCTCGCCGCGCAACTCAACGAGCCCGAGCCCGGCGTCGCGCCCACCGACTCGCGGCTGCGCCCCGACCAGCGCCTCATGGAGGAGGGCTGCTGGGACGAGGCCAACACGGAGAAGCTGCGCCTCGAGGAGAAGCAGCGGGGGGCGCGGCGCCGGCTGGAGGCGGAGGCCGAGGCGGCGGCCGCGCGCGGGCTGTCCGCCCCCGCCGCCCCGCCCCCGCTCTGGTTCACGAGGGACGCGCAGCCCGGCGCCGGGAACACGCTGCGCCACCTCTACAACCACCGCTACTGGGACTGCAAGCGCCGCCAGGACTGGACCGGCTGCCCGGATATTTTCTAG

Protein

MSEAIVPKGQPIPGDPEKKGWLFKWTNYLKGYQRRWFVLSNGLLSYYRNQAEMAHTCRGTISLLGALIHTADSCTFVISNGGTQTFYIKAHDEVERQSWVTALELAKAKAIRAQESDDDEDQVASGAVVIGGAGEGEGEDTGGIARELAARFHDLRTCSELVARHGTALQRSLVDLEIPPSDTTKQVSERATLFRISCNAMMNACSEFMSAAAGSSARLSRALQHEREQKLRLQEVVEQLARQHDTLEKTVTARSTPHTGGNGTTQGNETEDEDHEFFDAVEEGISTNMDDKTSFVIKVPVNRKNKVKDGESSDESEGETVTETQQVIFVEDKERAESAMGGADGSTTPSLPAKDTDIVVWELSKIPIPVNFSEPLSMLQRLTEDYEYSSVLDQAAKFDDPAQQLAYVAAFTVSSYATTACRTNKPFNPLLGETFECDRMADLGWRAISEQVSHHPPMVAQFCEGTSGWQCWQEFTMTTKFRGKYLQIIPLGAASAKFLAHGNKYTWRKVTTTVHNIIVGKLWVDNHGDMDIVGDAGPATGYVAHLKYLPYGYFSKDTQRKVTGVVKDPNGVPRYVLQGHWDSRVEVAPVTSTSADNSVCKTGKFVTAWQRVAAPPDSDKWYNFTVLAAQLNEPEPGVAPTDSRLRPDQRLMEEGCWDEANTEKLRLEEKQRGARRRLEAEAEAAAARGLSAPAAPPPLWFTRDAQPGAGNTLRHLYNHRYWDCKRRQDWTGCPDIF

Similarity

Belongs to the OSBP family.

Feature

chain  Oxysterol-binding protein

Uniprot

A0A2H1V134   A0A2A4K9L7   A0A437BIW8   A0A194QI89   A0A212FJ31   A0A2M4CW99   + More
A0A2M4CWG6   A0A2M4CWA3   A0A182IX75   G4WT22   A0A182VNF7   A0A1Q3F343   A0A1Q3F386   A0A1Q3F3D4   A0A1L8DYM4   A0A0K8TSP8   B0WDS0   A0A1S4G898   Q7QGU9   A0A182QLN9   G4WT23   A0A1Q3F391   A0A2M4BFD5   A0A1L8DM42   A0A2M3Z1U0   A0A2M4A457   A0A2M4A3Z1   A0A067QTR4   A0A336L515   A0A2M4CN67   A0A084VFI9   A0A2M3Z1F5   A0A1B0CCT6   A0A2M3Z1D5   A0A2M4A417   A0A1W7R8A0   A0A2M4A3C2   W5JHI2   A0A023F255   A0A0A9W5Q0   A0A0V0GAF6   A0A182YRK2   W8B0Q5   A0A069DX76   A0A1S4H633   A0A182F468   A0A224XJ76   A0A0K8VDF0   A0A182WYD1   A0A0A1WX18   D6WYT1   A0A0C9QA27   V5GSB5   A0A1J1I9E6   A0A1Q3G1F6   A0A1Q3G1G1   A0A195C8D1   V5G398   A0A0C9QWI3   L7MEV3   K7J5Q9   B4NI39   A0A1Z5L526   E2ADN3   A0A195E5Q1   A0A1Y1K1V9   A0A293LGL1   L7MC64   B7Q875   A0A2R5L8G9   B4PV10   A0A224Z0R9   A0A195B0S8   A0A131YSL8   A0A0P5VWD5   A0A1W4VKY8   V5HV65   A0A0P5JER8   A0A1Q3G1F9   A0A0M4EEK8   E0VJA4   B4LX15   B4K7U9   B3P6V1   E9GAA0   Q9VC05   B4QU78   B4HHP1   Q299T0   A0A195EV96   A0A0P5J4E7   O18397   B4G5P1   B3LWZ8   A0A0P4Y3M0   T1EER9   A0A1J1I5M0   A0A226E5R7  

Pubmed

26354079    22118469    21699592    26369729    17510324    12364791    + More
24845553    24438588    20920257    23761445    25474469    25401762    26823975    25244985    24495485    26334808    25830018    18362917    19820115    25576852    20075255    17994087    28528879    20798317    28004739    17550304    28797301    26830274    25765539    20566863    21292972    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    15632085    9473651    23254933   

EMBL

ODYU01000178    SOQ34529.1    NWSH01000035    PCG80420.1    RSAL01000051    RVE50235.1    + More
KQ458756    KPJ05232.1    AGBW02008320    OWR53753.1    GGFL01005428    MBW69606.1    GGFL01005427    MBW69605.1    GGFL01005429    MBW69607.1    JF309337    AEP20464.1    GFDL01013063    JAV21982.1    GFDL01013025    JAV22020.1    GFDL01013016    JAV22029.1    GFDF01002565    JAV11519.1    GDAI01000204    JAI17399.1    DS231900    EDS44823.1    AAAB01008823    EAA05572.4    AXCN02002119    JF309338    AEP20465.1    GFDL01013020    JAV22025.1    GGFJ01002625    MBW51766.1    GFDF01006639    JAV07445.1    GGFM01001657    MBW22408.1    GGFK01002189    MBW35510.1    GGFK01002202    MBW35523.1    KK853478    KDR07319.1    UFQS01001753    UFQT01001753    SSX12221.1    SSX31673.1    GGFL01002604    MBW66782.1    ATLV01012414    ATLV01012415    ATLV01012416    ATLV01012417    ATLV01012418    ATLV01012419    KE524791    KFB36733.1    GGFM01001592    MBW22343.1    AJWK01007082    AJWK01007083    AJWK01007084    AJWK01007085    AJWK01007086    AJWK01007087    AJWK01007088    AJWK01007089    AJWK01007090    GGFM01001589    MBW22340.1    GGFK01002178    MBW35499.1    GEHC01000253    JAV47392.1    GGFK01001993    MBW35314.1    ADMH02001239    ETN63541.1    GBBI01003050    JAC15662.1    GBHO01039827    GBHO01032464    GDHC01005420    JAG03777.1    JAG11140.1    JAQ13209.1    GECL01001895    JAP04229.1    GAMC01011880    JAB94675.1    GBGD01000597    JAC88292.1    GFTR01007916    JAW08510.1    GDHF01016533    GDHF01015739    JAI35781.1    JAI36575.1    GBXI01011111    GBXI01009807    JAD03181.1    JAD04485.1    KQ971357    EFA08460.1    GBYB01000079    JAG69846.1    GALX01003979    JAB64487.1    CVRI01000042    CRK95590.1    GFDL01001411    JAV33634.1    GFDL01001410    JAV33635.1    KQ978081    KYM97144.1    GALX01003981    JAB64485.1    GBYB01000080    JAG69847.1    GACK01003330    JAA61704.1    CH964272    EDW84731.1    GFJQ02004454    JAW02516.1    GL438820    EFN68395.1    KQ979608    KYN20493.1    GEZM01097815    JAV54090.1    GFWV01002231    MAA26961.1    GACK01003479    JAA61555.1    ABJB010048453    ABJB010089118    ABJB010095854    ABJB010104490    ABJB010457929    DS881486    EEC15047.1    GGLE01001675    MBY05801.1    CM000160    EDW98859.1    GFPF01010393    MAA21539.1    KQ976691    KYM77895.1    GEDV01006969    JAP81588.1    GDIP01094233    JAM09482.1    GANP01006225    JAB78243.1    GDIQ01203345    LRGB01002451    JAK48380.1    KZS07572.1    GFDL01001408    JAV33637.1    CP012526    ALC46441.1    DS235221    EEB13460.1    CH940650    EDW67762.1    CH933806    EDW16470.1    CH954182    EDV53771.1    GL732536    EFX83705.1    AE014297    AY129448    AAF56371.1    AAM76190.1    CM000364    EDX14315.1    CH480815    EDW43583.1    CM000070    EAL27621.1    KQ981965    KYN31817.1    GDIP01144627    GDIQ01203346    JAJ78775.1    JAK48379.1    Y13951    CAA74289.1    CH479179    EDW24907.1    CH902617    EDV43837.1    GDIP01233023    JAI90378.1    AMQM01002786    KB095858    ESO10964.1    CRK95589.1    LNIX01000006    OXA52983.1   

Proteomes

UP000218220    UP000283053    UP000053268    UP000007151    UP000075880    UP000075903    + More
UP000002320    UP000007062    UP000075886    UP000027135    UP000030765    UP000092461    UP000000673    UP000076408    UP000069272    UP000076407    UP000007266    UP000183832    UP000078542    UP000002358    UP000007798    UP000000311    UP000078492    UP000001555    UP000002282    UP000078540    UP000192221    UP000076858    UP000092553    UP000009046    UP000008792    UP000009192    UP000008711    UP000000305    UP000000803    UP000000304    UP000001292    UP000001819    UP000078541    UP000008744    UP000007801    UP000015101    UP000198287   

PRIDE

Q9VC05    O18397   

Pfam

PF01237   Oxysterol_BP        + More
PF00169   PH
PF00069   Pkinase
PF14438   SM-ATX
PF06741   LsmAD

Interpro

IPR001849   PH_domain        + More
IPR011993   PH-like_dom_sf       
IPR000648   Oxysterol-bd       
IPR037239   OSBP_sf       
IPR018494   Oxysterol-bd_CS       
IPR008271   Ser/Thr_kinase_AS       
IPR011009   Kinase-like_dom_sf       
IPR017441   Protein_kinase_ATP_BS       
IPR000719   Prot_kinase_dom       
IPR009604   LsmAD_domain       
IPR025852   SM_dom_ATX       

SUPFAM

SSF144000   SSF144000        + More
SSF56112   SSF56112       

Gene 3D

2.30.29.30    

ProteinModelPortal

A0A2H1V134   A0A2A4K9L7   A0A437BIW8   A0A194QI89   A0A212FJ31   A0A2M4CW99   + More
A0A2M4CWG6   A0A2M4CWA3   A0A182IX75   G4WT22   A0A182VNF7   A0A1Q3F343   A0A1Q3F386   A0A1Q3F3D4   A0A1L8DYM4   A0A0K8TSP8   B0WDS0   A0A1S4G898   Q7QGU9   A0A182QLN9   G4WT23   A0A1Q3F391   A0A2M4BFD5   A0A1L8DM42   A0A2M3Z1U0   A0A2M4A457   A0A2M4A3Z1   A0A067QTR4   A0A336L515   A0A2M4CN67   A0A084VFI9   A0A2M3Z1F5   A0A1B0CCT6   A0A2M3Z1D5   A0A2M4A417   A0A1W7R8A0   A0A2M4A3C2   W5JHI2   A0A023F255   A0A0A9W5Q0   A0A0V0GAF6   A0A182YRK2   W8B0Q5   A0A069DX76   A0A1S4H633   A0A182F468   A0A224XJ76   A0A0K8VDF0   A0A182WYD1   A0A0A1WX18   D6WYT1   A0A0C9QA27   V5GSB5   A0A1J1I9E6   A0A1Q3G1F6   A0A1Q3G1G1   A0A195C8D1   V5G398   A0A0C9QWI3   L7MEV3   K7J5Q9   B4NI39   A0A1Z5L526   E2ADN3   A0A195E5Q1   A0A1Y1K1V9   A0A293LGL1   L7MC64   B7Q875   A0A2R5L8G9   B4PV10   A0A224Z0R9   A0A195B0S8   A0A131YSL8   A0A0P5VWD5   A0A1W4VKY8   V5HV65   A0A0P5JER8   A0A1Q3G1F9   A0A0M4EEK8   E0VJA4   B4LX15   B4K7U9   B3P6V1   E9GAA0   Q9VC05   B4QU78   B4HHP1   Q299T0   A0A195EV96   A0A0P5J4E7   O18397   B4G5P1   B3LWZ8   A0A0P4Y3M0   T1EER9   A0A1J1I5M0   A0A226E5R7  

PDB

5ZM7     E-value=2.71378e-49,     Score=496

KEGG

101744508    K20456 oxysterol-binding protein 1 | (RefSeq) oxysterol-binding protein 1

GO

GO:0006869   GO:0005829   GO:0005886   GO:0097038   GO:0032934   GO:0016020   GO:0015248   GO:0043231   GO:0008289   GO:0016021   GO:0004672   GO:0005524   GO:0005783   GO:0006886   GO:0005794   GO:0007030   GO:0007291   GO:0016740  

PANTHER

PTHR10972  

Length:

737

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.13693

Exp number, first 60 AAs:

0.01233

Total prob of N-in:

0.00519

outside

1  -  737

 

 

Pi

197.600127

Theta

175.56977

Tajima's D

-1.751203

CLR

13.186955

CSRT

0.031998400079996

Interpretation

Possibly Positive selection