Gene

KWMTBOMO09776  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012922

Annotation

PREDICTED:_AP-1_complex_subunit_beta-1_[Papilio_xuthus]

Location

Bomo_Chr16(-):9002735-9016559      View in EpiBrowser

Full name

AP complex subunit beta       + More
Beta-adaptin-like protein      

Location in the cell

Golgi   Reliability : 2.517

CDS

ATGACTGATTCCAAGTACTTCACCACTACGAAGAAAGGAGAGATATTCGAGTTGAAATCGGAACTAAACTCTGACAAAAAAGAGAAAAAGAAGGAGGCCGTTAAAAAGGTTATAGCATCCATGACAGTTGGAAAAGACGTCTCAGCATTGTTCCCCGATGTCGTGAATTGCATGCAGACAGATAACTTAGAACTGAAAAAACTGGTGTACTTATATTTAATGAATTATGCAAAGTCACAGCCAGACATGGCTATCATGGCGGTCAATACTTTTGTCAAGGACTGTGAGGATTCCAATCCATTGATTCGAGCTTTGGCTGTACGGACTATGGGATGCATTCGAGTGGACAAGATTACAGAATATCTATGCGAACCATTAAGAAAGTGCCTGAAAGATGAAGATCCTTATGTCCGGAAGACTGCAGCCGTGTGCGTCGCAAAGTTATATGATATCTCTTCAAGCATGGTTGAAGATCAGGGCTTCTTAGATCAACTAAAAGATCTGTTGAGCGATTCGAATCCTATGGTAGTAGCAAACGCTGTGGCAGCCTTATCAGAAATCAACGAAGCTAGTGTTTCTGGACGGCCCCTTGTTGAAATGAATGCCCCAACGATCAACAAGCTGTTGACTGCGTTGAATGAGTGTACTGAATGGGGTCAGGTGTTCATCCTGGACGCGTTGTCCAACTACTCGCCGCGTGACGCCCGCGAGGCGCACTCCATCTGCGAGAGGATCACGCCCCGCCTGGCGCACGCCAACGCCGCCGTCGTGCTCTCCGCTGTCAAGGTGCTGATGAAGCTGATGGAGATGGTGTCGGCGGACACGGAGCTGGTGAGCACGCTGTCCCGCAAGCTGGCGCCGCCGCTGGTGACGCTGCTGAGCGCGGAGCCCGAGGTGCAGTACGTGGCGCTGCGGAACATCAACCTCGTCGTGCAGAAGCGACCAGACATACTCAAACACGAGATGAAGGTGTTCTTTGTGAAGTACAATGACCCGATCTACGTTAAACTGGAGAAACTGGACATAATGATCCGATTGGCTTCCCAAGCCAACATAGCCCAGGTGCTCGGGGAACTGAAGGAGTATGCCACCGAAGTGGACGTGGACTTCGTCCGGAAGGCCGTCAGGGCTATAGGCAGATGCGCCATCAAGGTAGAGCCGTCGGCGGAGCGTTGCGTCTCTACATTACTAGAGCTGATCCAGACCAAAGTGAACTACGTCGTGCAAGAGGCCATTGTGGTGATCAAAGACATATTCAGAAAGTACCCGAACAAGTATGAGAGCATCATCAGTACGCTGTGCGAAAATCTTGATACTTTAGACGAGCCTGAGGCTAGGGCTTCCATGGTATGGATTGTGGGCGAATACGCGGAACGTATCGACAACGCAGACGAACTTCTAGATTCGTTCCTCGAAGGGTTCCACGATGAAAACGCACAGGTACAACTGCAACTCCTCACGGCCGTTGTGAAACTGTTCCTGAAACGTCCAGCCGACACGCAAGAGCTAGTACAGCACGTGCTTAGTCTGGCAACACAGGATTCGGACAATCCCGACTTGAGAGACCGCGGCTTCATCTACTGGCGTCTACTGTCGACCGACCCGGCCGCGGCCAAGGAAGTGGTCCTGGCCGACAAGCCTCTCATATCGGAGGAGACTGATCTTCTGGAACCCACACTACTGGACGAACTCATCTGCCACATCAGCTCGCTGGCTTCGGTCTATCACAAGCCACCGACGGCATTCGTTGAAGGCCGCGGCGCCGGAGTCCGCAAGTCCCTGCCGTCCCGAGGTGTTGTCGCCGAAGAAACGAACACACAACAACCCACAGTCATCCCGAATCAGGAGTCGTTGATCGGCGATCTATTGTCTATGGACATCGGAGGTCCCCCCCCGGCCCCGGCGCCCTCTTCCAACGTCGACCTCCTCGCCGGCGGACTAGATGTTCTCTTGGGCGGCGGGCCGGAGCCGGGCGCGTCCGCCGCGGCGGTCCCCGGCGGCGCCTCCGGCCTGCTCGGCGACATCTTCGCCGTCTCCGCCGCGCCCGCCTCCTACGTGCCGCCCAAACAGTGCTGGCTGCCCGCCGACAAAGGAAAAGGTTTGGAGATTTGGGGTACGTTCAGCCGTCAGAACGGTCAGCCTCGGATGGAGATGACATTCACTAACAAGGCGATGCAGCCGATGACAGGTTTCGCCATACAACTCAATAAGAACAGTTTCGGCGTTTATCCTGTGGGCGGGCTGGCGGTGGGCGCGGTGGGGGCGGGCGCGGGCGCGGAGGCCGCACTGCCGCTCGCCACGCACGGGCCCGTGCAACGCATGGACCCGCTCAACAACCTACAGGTCGCGATAAAGAACAATATAGATGTATTCTACTTCGCCTGCCTAATCCCCGCTCACATATTATTCACGGAAGACGGACAGCTAGACAAACGTGTGTTCCTCACGACTTGGAAGGAAATACCCGCAGCGAACGAAGTACAACATACACTATCGAACGTTGTGGGAACAGCCGATTCTATCGCTCAAAAAATGACGCTAAACAATATCTTTACTATCGCTAAACGTAATGTCGAAGGTCAAGATATGTTATATCAATCATTGAAGTTAACTAACAACATCTGGGTGTTGCTAGAGTTGAAACTTCAGCCCGGCAACCCCGAAGCGACGCTCAGCTTGAAGTCCCGAACTGTAGAGGTCGCCACGTGTATATTCCAAGCCTACGAAGCTATAATCAAATCGTAA

Protein

MTDSKYFTTTKKGEIFELKSELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDSNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLYDISSSMVEDQGFLDQLKDLLSDSNPMVVANAVAALSEINEASVSGRPLVEMNAPTINKLLTALNECTEWGQVFILDALSNYSPRDAREAHSICERITPRLAHANAAVVLSAVKVLMKLMEMVSADTELVSTLSRKLAPPLVTLLSAEPEVQYVALRNINLVVQKRPDILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLGELKEYATEVDVDFVRKAVRAIGRCAIKVEPSAERCVSTLLELIQTKVNYVVQEAIVVIKDIFRKYPNKYESIISTLCENLDTLDEPEARASMVWIVGEYAERIDNADELLDSFLEGFHDENAQVQLQLLTAVVKLFLKRPADTQELVQHVLSLATQDSDNPDLRDRGFIYWRLLSTDPAAAKEVVLADKPLISEETDLLEPTLLDELICHISSLASVYHKPPTAFVEGRGAGVRKSLPSRGVVAEETNTQQPTVIPNQESLIGDLLSMDIGGPPPAPAPSSNVDLLAGGLDVLLGGGPEPGASAAAVPGGASGLLGDIFAVSAAPASYVPPKQCWLPADKGKGLEIWGTFSRQNGQPRMEMTFTNKAMQPMTGFAIQLNKNSFGVYPVGGLAVGAVGAGAGAEAALPLATHGPVQRMDPLNNLQVAIKNNIDVFYFACLIPAHILFTEDGQLDKRVFLTTWKEIPAANEVQHTLSNVVGTADSIAQKMTLNNIFTIAKRNVEGQDMLYQSLKLTNNIWVLLELKLQPGNPEATLSLKSRTVEVATCIFQAYEAIIKS

Description

Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

Subunit

Adaptor protein complexes are heterotetramers composed of two large adaptins (beta-type subunit and alpha-type or delta-type or epsilon-type or gamma-type subunit), a medium adaptin (mu-type subunit) and a small adaptin (sigma-type subunit).

Similarity

Belongs to the adaptor complexes large subunit family.

Uniprot

A0A437BU43   A0A2W1BYJ0   A0A2A4J8Z2   A0A0N1I9A1   A0A212FMC3   B4MA28   + More
A0A0K8TY54   A0A034VKS9   B3NVT4   A0A1B0CED0   B4PZ07   A0A0A1WPY7   W8C5S6   B4JWU0   A0A1A9WDQ1   A0A1L8DVN8   B4NQ71   A0A0L0CKZ8   A0A0M4EWR3   B4L6V2   A0A1B0FI36   A0A1A9USV6   A0A1B0BB68   A0A1A9ZQI5   A0A1A9XCV0   A0A1Q3FY77   A0A1Y1LRA6   A0A1Q3FYB2   A0A1I8M3S5   A0A1I8NU89   A0A1W4XVD0   V5I8R8   U5EX18   E9J8K4   A0A158NBU8   K7ISE6   A0A2J7PX15   A0A1B6GJW3   A0A1B6IZT0   E2ACH8   A0A195BF10   A0A0C9QZS2   A0A067R983   A0A0A9Y0B4   A0A0C9R328   N6UAJ9   A0A069DWU5   A0A023F5S2   A0A224XE67   A0A0P4W4K3   A0A2P8ZJQ9   E0VK25   A0A0J7KLI9   A0A1B6DGS2   A0A0L7QWP9   A0A088AH86   A0A2G3AQQ1   F4X887   A0A195FDW1   V9I9B6   A0A2S2P3D1   A0A0N0BFV5   J9K6T5   A0A2A3ETU6   A0A195C9K4   A0A1B6BYD6   V9IAN3   A0A0P5P0E4   A0A0P6FYT9   A0A0P6EL28   A0A0P5MTA5   A0A0P6DXK2   A0A0P6G5U3   A0A0P5QZM6   A0A0P5RT68   A0A0P5K670   A0A0P5JVD7   A0A0P5RYG8   A0A0P5PUF0   A0A0N8C123   A0A0P5NT51   A0A0P6ET47   A0A0N8BXF5   A0A0P6DRX0   A0A0P5J4G0   A0A0P5KBT6   A0A151X9P3   A0A0P6G9T0   A0A0P5HDM1   A0A0P5S4Q2   A0A0P6ELN1   A0A0P5N8H0   A0A151J959   A0A0N8DUR1   A0A0N8C786   A0A0P6HE64   A0A3S3S074   A0A0K2UUH0   A0A132A7P0   A0A0P5BVX6  

Pubmed

28756777    26354079    22118469    17994087    18057021    25348373    + More
17550304    25830018    24495485    26108605    28004739    25315136    21282665    21347285    20075255    20798317    24845553    25401762    26823975    23537049    26334808    25474469    27129103    29403074    20566863    29089032    21719571    26555130   

EMBL

RSAL01000008    RVE54002.1    KZ149898    PZC78664.1    NWSH01002600    PCG67882.1    + More
KQ460635    KPJ13437.1    AGBW02007651    OWR54895.1    CH940655    EDW66087.1    KRF82552.1    GDHF01033299    GDHF01025458    JAI19015.1    JAI26856.1    GAKP01015031    JAC43921.1    CH954180    EDV46749.1    AJWK01008737    CM000162    EDX02085.1    GBXI01013400    JAD00892.1    GAMC01001552    JAC05004.1    CH916376    EDV95216.1    GFDF01003587    JAV10497.1    CH964291    EDW86296.1    JRES01000256    KNC32921.1    CP012528    ALC49947.1    CH933812    EDW06098.1    CCAG010004713    JXJN01011309    GFDL01002520    JAV32525.1    GEZM01054557    JAV73557.1    GFDL01002514    JAV32531.1    GALX01004210    JAB64256.1    GANO01001165    JAB58706.1    GL769034    EFZ10863.1    ADTU01011328    ADTU01011329    NEVH01020862    PNF20877.1    GECZ01007088    JAS62681.1    GECU01022471    GECU01015297    JAS85235.1    JAS92409.1    GL438525    EFN68864.1    KQ976500    KYM83163.1    GBYB01001215    JAG70982.1    KK852619    KDR20112.1    GBHO01018015    GBRD01016397    GDHC01002092    JAG25589.1    JAG49429.1    JAQ16537.1    GBYB01001216    JAG70983.1    APGK01036711    KB740941    ENN77661.1    GBGD01000356    JAC88533.1    GBBI01002190    JAC16522.1    GFTR01008338    JAW08088.1    GDKW01000326    JAI56269.1    PYGN01000035    PSN56732.1    DS235237    EEB13731.1    LBMM01005718    KMQ91273.1    GEDC01012407    JAS24891.1    KQ414713    KOC62964.1    MCIT02003576    PHT96513.1    GL888932    EGI57163.1    KQ981673    KYN38392.1    JR037303    JR037304    AEY57698.1    AEY57699.1    GGMR01011265    MBY23884.1    KQ435794    KOX73888.1    ABLF02024989    KZ288189    PBC34636.1    KQ978068    KYM97544.1    GEDC01031006    JAS06292.1    JR037301    JR037302    AEY57696.1    AEY57697.1    GDIQ01135418    JAL16308.1    GDIQ01058846    JAN35891.1    GDIQ01061047    JAN33690.1    GDIQ01151517    JAL00209.1    GDIQ01244794    GDIQ01169655    GDIQ01117434    GDIQ01079279    GDIQ01071690    LRGB01001005    JAN23047.1    KZS14136.1    GDIQ01038007    JAN56730.1    GDIQ01107972    JAL43754.1    GDIQ01096479    JAL55247.1    GDIQ01194599    JAK57126.1    GDIQ01194598    JAK57127.1    GDIQ01112374    GDIQ01112373    JAL39353.1    GDIQ01123220    JAL28506.1    GDIQ01125275    JAL26451.1    GDIQ01138125    JAL13601.1    GDIQ01071691    JAN23046.1    GDIQ01135419    JAL16307.1    GDIQ01074537    JAN20200.1    GDIQ01211087    JAK40638.1    GDIQ01192798    JAK58927.1    KQ982373    KYQ57039.1    GDIQ01038008    JAN56729.1    GDIQ01231383    JAK20342.1    GDIQ01092438    JAL59288.1    GDIQ01074536    JAN20201.1    GDIQ01156900    JAK94825.1    KQ979433    KYN21576.1    GDIQ01089980    JAN04757.1    GDIQ01107971    JAL43755.1    GDIQ01021271    JAN73466.1    NCKU01002919    RWS08542.1    HACA01024503    CDW41864.1    JXLN01011010    KPM06655.1    GDIP01179824    JAJ43578.1   

Proteomes

UP000283053    UP000218220    UP000053240    UP000007151    UP000008792    UP000008711    + More
UP000092461    UP000002282    UP000001070    UP000091820    UP000007798    UP000037069    UP000092553    UP000009192    UP000092444    UP000078200    UP000092460    UP000092445    UP000092443    UP000095301    UP000095300    UP000192223    UP000005205    UP000002358    UP000235965    UP000000311    UP000078540    UP000027135    UP000019118    UP000245037    UP000009046    UP000036403    UP000053825    UP000005203    UP000224522    UP000007755    UP000078541    UP000053105    UP000007819    UP000242457    UP000078542    UP000076858    UP000075809    UP000078492    UP000285301   

Pfam

PF02883   Alpha_adaptinC2        + More
PF09066   B2-adapt-app_C
PF01602   Adaptin_N
PF03456   uDENN
PF12335   SBF2
PF02893   GRAM
PF02141   DENN
PF00169   PH
PF00130   C1_1
PF06602   Myotub-related
PF01451   LMWPc

Interpro

IPR026739   AP_beta        + More
IPR012295   TBP_dom_sf       
IPR013037   Clathrin_b-adaptin_app_Ig-like       
IPR016024   ARM-type_fold       
IPR011989   ARM-like       
IPR008152   Clathrin_a/b/g-adaptin_app_Ig       
IPR009028   Coatomer/calthrin_app_sub_C       
IPR016342   AP_complex_bsu_1_2_4       
IPR015151   B-adaptin_app_sub_C       
IPR002553   Clathrin/coatomer_adapt-like_N       
IPR013041   Clathrin_app_Ig-like_sf       
IPR022096   SBF1/SBF2       
IPR037516   Tripartite_DENN       
IPR001849   PH_domain       
IPR001194   cDENN_dom       
IPR004182   GRAM       
IPR005113   uDENN_dom       
IPR010569   Myotubularin-like_Pase_dom       
IPR030564   Myotubularin_fam       
IPR029021   Prot-tyrosine_phosphatase-like       
IPR011993   PH-like_dom_sf       
IPR005112   dDENN_dom       
IPR002219   PE/DAG-bd       
IPR036196   Ptyr_pPase_sf       
IPR023485   Ptyr_pPase       
IPR017867   Tyr_phospatase_low_mol_wt       
IPR000225   Armadillo       

SUPFAM

SSF48371   SSF48371        + More
SSF55711   SSF55711       
SSF49348   SSF49348       
SSF52799   SSF52799       
SSF52788   SSF52788       

Gene 3D

1.25.10.10     2.60.40.1150     3.30.310.10     2.30.29.30    

CDD

cd00029  C1

ProteinModelPortal

A0A437BU43   A0A2W1BYJ0   A0A2A4J8Z2   A0A0N1I9A1   A0A212FMC3   B4MA28   + More
A0A0K8TY54   A0A034VKS9   B3NVT4   A0A1B0CED0   B4PZ07   A0A0A1WPY7   W8C5S6   B4JWU0   A0A1A9WDQ1   A0A1L8DVN8   B4NQ71   A0A0L0CKZ8   A0A0M4EWR3   B4L6V2   A0A1B0FI36   A0A1A9USV6   A0A1B0BB68   A0A1A9ZQI5   A0A1A9XCV0   A0A1Q3FY77   A0A1Y1LRA6   A0A1Q3FYB2   A0A1I8M3S5   A0A1I8NU89   A0A1W4XVD0   V5I8R8   U5EX18   E9J8K4   A0A158NBU8   K7ISE6   A0A2J7PX15   A0A1B6GJW3   A0A1B6IZT0   E2ACH8   A0A195BF10   A0A0C9QZS2   A0A067R983   A0A0A9Y0B4   A0A0C9R328   N6UAJ9   A0A069DWU5   A0A023F5S2   A0A224XE67   A0A0P4W4K3   A0A2P8ZJQ9   E0VK25   A0A0J7KLI9   A0A1B6DGS2   A0A0L7QWP9   A0A088AH86   A0A2G3AQQ1   F4X887   A0A195FDW1   V9I9B6   A0A2S2P3D1   A0A0N0BFV5   J9K6T5   A0A2A3ETU6   A0A195C9K4   A0A1B6BYD6   V9IAN3   A0A0P5P0E4   A0A0P6FYT9   A0A0P6EL28   A0A0P5MTA5   A0A0P6DXK2   A0A0P6G5U3   A0A0P5QZM6   A0A0P5RT68   A0A0P5K670   A0A0P5JVD7   A0A0P5RYG8   A0A0P5PUF0   A0A0N8C123   A0A0P5NT51   A0A0P6ET47   A0A0N8BXF5   A0A0P6DRX0   A0A0P5J4G0   A0A0P5KBT6   A0A151X9P3   A0A0P6G9T0   A0A0P5HDM1   A0A0P5S4Q2   A0A0P6ELN1   A0A0P5N8H0   A0A151J959   A0A0N8DUR1   A0A0N8C786   A0A0P6HE64   A0A3S3S074   A0A0K2UUH0   A0A132A7P0   A0A0P5BVX6  

PDB

6DFF     E-value=0,     Score=2478

KEGG

101740876    K12392 AP-1 complex subunit beta-1 | (RefSeq) AP-1 complex subunit beta-1

PATHWAY

04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0030276   GO:0030131   GO:0006886   GO:0016192   GO:0010508   GO:0005802   GO:0005886   GO:0030136   GO:0048749   GO:0005905   GO:0035556   GO:0046872   GO:0004725   GO:0016020   GO:0015031   GO:0005737   GO:0030117   GO:0005488   GO:0008565   GO:0009258   GO:0016155   GO:0003824  

PANTHER

PTHR11134   PTHR10807  

Subcellular location

Cytoplasm  

Length:

914

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.858739999999998

Exp number, first 60 AAs:

0.0066

Total prob of N-in:

0.00200

outside

1  -  914

 

 

Pi

244.867794

Theta

167.406256

Tajima's D

1.475001

CLR

0.068729

CSRT

0.780510974451277

Interpretation

Uncertain