Gene

KWMTBOMO09749  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012934

Annotation

actin_related_protein_2/3_complex_subunit_4_[Bombyx_mori]

Location

Bomo_Chr16(-):8701576-8702160      View in EpiBrowser

Full name

Actin-related protein 2/3 complex subunit 4      

Location in the cell

Cytoplasmic   Reliability : 1.29 Mitochondrial   Reliability : 1.212

CDS

ATGGCTGCAACTTTAAAACCGTATCTAACAGCGGTGCGTCACACGCTCACTGCCGCTATGTGCTTAGAACACTTTTCATCGCAAGTTGTCGAGAAATACACCAAGCCGGAGGTCGAAGTTAGAACAAGCAAAGAACTTTTACTCAATCCTGTTGTTATTTCAAGAAATTCTAATGAAAAAGTATTAATAGAGTCTTCAATAAATTCAATTAGGGTGAGTATTATGATCAAGCAGGCGGATGAGATAGAGAAAATTCTTTGTAAAAAATTTATGCGGTTCATGATGATGAGAGCTGAAAACTTCATTGTATTAAGGAGGAAACCAGTTGATGGGTACCATATCAGCTTTTTGATTACTAACTTCCATACCGAACAGATGTATAAGCATAAATTGGTCGATTTTGTAATATACTTTATGGAAGAAATTGATAAAGAAATCAGTGAAATGAAATTGGCTGTCAATGCAAGAGCCAGAATTTGTTCGGAAGAATTCTTGAAGAGATTTTAA

Protein

MAATLKPYLTAVRHTLTAAMCLEHFSSQVVEKYTKPEVEVRTSKELLLNPVVISRNSNEKVLIESSINSIRVSIMIKQADEIEKILCKKFMRFMMMRAENFIVLRRKPVDGYHISFLITNFHTEQMYKHKLVDFVIYFMEEIDKEISEMKLAVNARARICSEEFLKRF

Description

Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.

Similarity

Belongs to the ARPC4 family.

Uniprot

Q1HPT2   A0A2W1C0K9   A0A2A4K3J7   A0A0L7L8M3   A0A2H1V4T4   X4Z1B2   + More
A0A3S2LUH6   A0A194R276   A0A194Q5Z2   A0A2P8XRL7   A0A0T6B152   A0A226EWT5   A0A182SJZ9   A0A182YBE0   A0A182PTS0   A0A182M1X8   A0A182Q4M7   A0A182NR76   A0A182VVT4   A0A182TVD0   A0A182X9K7   A0A182L8T5   Q7PUB7   A0A182RNJ7   A0A182HKJ0   A0A1D2NGH8   A0A182V4U4   A0A023EHV7   A0A1Y1MQE2   T1E8K8   A0A2M3Z8U7   A0A2M4APG7   W5J3R1   A0A084VXV3   A0A182IXM0   A0A182FRK7   D2A6A8   A0A1L8E5Q5   A0A1B0GI81   A0A1Q3FG03   B0X5P8   Q16WZ0   U5ELN7   A0A2L2Y2K6   T1DSL0   A0A0P5KDK0   A0A224YIR3   A0A0K8RH12   A0A212FMJ7   A0A1E1WWE6   A0A087U3N5   A0A1J1ITS5   A0A131Z4K4   L7LY75   A0A131XIW3   A0A023FHE6   S4PL32   A0A1B6D5I3   A0A1W4X8B9   A0A1E1XUH2   A0A023FEX5   A0A2A4K3Z8   G3MNL8   A0A1S3D024   A0A2R5LNJ4   A0A1B6J3U4   E0VA94   A0A0K8TLR8   A0A1B6LN36   A0A182K4E5   A0A023NL51   A0A2R7WRQ9   R7UGT8   A0A0L8FI18   A0A293M415   A0A3M6T475   A0A1B6HV00   A0A1Z5KUB3   A0A0K8SJF4   A7RRG4   N6UG83   A0A147BA47   T1F6L5   A0A3P8TMD2   A0A3B1JWY7   A0A3B4CCU3   A0A1S3JQ95   A0A1A8M9H1   A0A0E9X7D4   A0A1A8ATX8   R4WDL1   A0A1W4Z8H0   F7FPY5   W8C601   A0A0K8UZ82   A0A034VPQ5   A0A3B4XFD9   A0A3Q2P008   A0A3Q2DSM1   A0A3B3YZY1  

Pubmed

28756777    26227816    26354079    29403074    25244985    20966253    + More
12364791    14747013    17210077    27289101    24945155    26483478    28004739    20920257    23761445    24438588    18362917    19820115    17510324    26561354    28797301    22118469    28503490    26830274    25576852    28049606    23622113    29209593    22216098    20566863    26369729    24733187    23254933    30382153    28528879    26823975    17615350    23537049    25329095    25613341    23691247    18464734    24495485    25348373   

EMBL

DQ443320    ABF51409.1    KZ149898    PZC78650.1    NWSH01000188    PCG78629.1    + More
JTDY01002320    KOB71664.1    ODYU01000678    SOQ35860.1    KJ187401    AHV90276.1    RSAL01000008    RVE54019.1    KQ460878    KPJ11619.1    KQ459582    KPI98825.1    PYGN01001468    PSN34646.1    LJIG01016367    KRT80814.1    LNIX01000001    OXA61650.1    AXCM01001747    AXCN02001469    AAAB01008987    EAA01786.3    APCN01000833    LJIJ01000056    ODN04066.1    JXUM01000125    JXUM01055969    GAPW01005137    KQ561891    KQ560101    JAC08461.1    KXJ77244.1    KXJ84563.1    GEZM01027049    JAV86850.1    GAMD01002678    JAA98912.1    GGFM01004206    MBW24957.1    GGFK01009326    MBW42647.1    ADMH02002105    GGFL01004229    ETN59007.1    MBW68407.1    ATLV01018208    KE525224    KFB42797.1    AXCP01002658    KQ971347    EFA05486.1    GFDF01000125    JAV13959.1    AJWK01013570    GFDL01008566    JAV26479.1    DS232391    EDS40985.1    CH477549    EAT39131.1    GANO01001329    JAB58542.1    IAAA01004181    LAA02402.1    GAMD01000150    JAB01441.1    GDIQ01192109    GDIP01068718    LRGB01001005    JAK59616.1    JAM34997.1    KZS14177.1    GFPF01005709    MAA16855.1    GADI01003378    JAA70430.1    AGBW02007651    OWR54909.1    GFAC01007835    JAT91353.1    KK118013    KFM71974.1    CVRI01000057    CRL01921.1    GEDV01002649    JAP85908.1    GACK01008294    JAA56740.1    GEFH01002279    JAP66302.1    GBBK01004027    JAC20455.1    GAIX01000781    JAA91779.1    GEDC01016356    JAS20942.1    GFAA01000658    JAU02777.1    GBBK01004026    JAC20456.1    PCG78628.1    JO843469    AEO35086.1    GGLE01006899    MBY11025.1    GECU01027313    GECU01013860    JAS80393.1    JAS93846.1    DS235005    EEB10300.1    GDAI01002728    JAI14875.1    GEBQ01014988    JAT24989.1    KF780489    AHX02953.1    KK855372    PTY22246.1    AMQN01008807    KB304010    ELU02472.1    KQ431294    KOF63267.1    GFWV01010307    MAA35036.1    RCHS01004365    RMX35032.1    GECU01029214    GECU01011366    JAS78492.1    JAS96340.1    GFJQ02008278    JAV98691.1    GBRD01012391    GDHC01021963    JAG53433.1    JAP96665.1    DS469531    EDO46006.1    APGK01036710    KB740941    KB632225    ENN77657.1    ERL90283.1    GEIB01000745    JAR87245.1    AMQM01004492    KB096590    ESO03545.1    HAEF01012052    SBR53211.1    GBXM01009915    JAH98662.1    HADY01019210    SBP57695.1    AK417624    BAN20839.1    GAMC01004594    JAC01962.1    GDHF01020332    GDHF01007226    JAI31982.1    JAI45088.1    GAKP01015167    GAKP01015165    GAKP01015163    JAC43785.1   

Proteomes

UP000218220    UP000037510    UP000283053    UP000053240    UP000053268    UP000245037    + More
UP000198287    UP000075901    UP000076408    UP000075885    UP000075883    UP000075886    UP000075884    UP000075920    UP000075902    UP000076407    UP000075882    UP000007062    UP000075900    UP000075840    UP000094527    UP000075903    UP000069940    UP000249989    UP000000673    UP000030765    UP000075880    UP000069272    UP000007266    UP000092461    UP000002320    UP000008820    UP000076858    UP000007151    UP000054359    UP000183832    UP000192223    UP000079169    UP000009046    UP000075881    UP000014760    UP000053454    UP000275408    UP000001593    UP000019118    UP000030742    UP000015101    UP000265080    UP000018467    UP000261440    UP000085678    UP000192224    UP000002279    UP000261360    UP000265000    UP000265020    UP000261480   

PRIDE

Q1HPT2    L7LY75   

Pfam

PF05856   ARPC4

Interpro

IPR008384   ARPC4        + More
IPR034666   ARPC2/4       

SUPFAM

SSF69645   SSF69645       

Gene 3D

3.30.1460.20    

ProteinModelPortal

Q1HPT2   A0A2W1C0K9   A0A2A4K3J7   A0A0L7L8M3   A0A2H1V4T4   X4Z1B2   + More
A0A3S2LUH6   A0A194R276   A0A194Q5Z2   A0A2P8XRL7   A0A0T6B152   A0A226EWT5   A0A182SJZ9   A0A182YBE0   A0A182PTS0   A0A182M1X8   A0A182Q4M7   A0A182NR76   A0A182VVT4   A0A182TVD0   A0A182X9K7   A0A182L8T5   Q7PUB7   A0A182RNJ7   A0A182HKJ0   A0A1D2NGH8   A0A182V4U4   A0A023EHV7   A0A1Y1MQE2   T1E8K8   A0A2M3Z8U7   A0A2M4APG7   W5J3R1   A0A084VXV3   A0A182IXM0   A0A182FRK7   D2A6A8   A0A1L8E5Q5   A0A1B0GI81   A0A1Q3FG03   B0X5P8   Q16WZ0   U5ELN7   A0A2L2Y2K6   T1DSL0   A0A0P5KDK0   A0A224YIR3   A0A0K8RH12   A0A212FMJ7   A0A1E1WWE6   A0A087U3N5   A0A1J1ITS5   A0A131Z4K4   L7LY75   A0A131XIW3   A0A023FHE6   S4PL32   A0A1B6D5I3   A0A1W4X8B9   A0A1E1XUH2   A0A023FEX5   A0A2A4K3Z8   G3MNL8   A0A1S3D024   A0A2R5LNJ4   A0A1B6J3U4   E0VA94   A0A0K8TLR8   A0A1B6LN36   A0A182K4E5   A0A023NL51   A0A2R7WRQ9   R7UGT8   A0A0L8FI18   A0A293M415   A0A3M6T475   A0A1B6HV00   A0A1Z5KUB3   A0A0K8SJF4   A7RRG4   N6UG83   A0A147BA47   T1F6L5   A0A3P8TMD2   A0A3B1JWY7   A0A3B4CCU3   A0A1S3JQ95   A0A1A8M9H1   A0A0E9X7D4   A0A1A8ATX8   R4WDL1   A0A1W4Z8H0   F7FPY5   W8C601   A0A0K8UZ82   A0A034VPQ5   A0A3B4XFD9   A0A3Q2P008   A0A3Q2DSM1   A0A3B3YZY1  

PDB

6DEC     E-value=6.20696e-66,     Score=631

KEGG

732988    K05755 actin related protein 2/3 complex, subunit 4 | (RefSeq) actin related protein 2/3 complex sub

PATHWAY

04144    Endocytosis - Bombyx mori (domestic silkworm)

GO

GO:0034314   GO:0005885   GO:0005737   GO:0003779   GO:0030041   GO:0019899   GO:0030674   GO:0051015   GO:0005200   GO:0015629   GO:0030130   GO:0030132   GO:0005488   GO:0005515   GO:0009258   GO:0016155   GO:0003824   GO:0030833  

PANTHER

PTHR22629  

Subcellular location

  

Length:

168

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01622

Exp number, first 60 AAs:

0.00295

Total prob of N-in:

0.11913

outside

1  -  168

 

 

Pi

223.450241

Theta

143.49186

Tajima's D

1.799648

CLR

86.652069

CSRT

0.849907504624769

Interpretation

Uncertain