Gene

KWMTBOMO09728

Pre Gene Modal

BGIBMGA012892

Annotation

PREDICTED:_luciferin_4-monooxygenase-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr16(+):8180432-8182862      View in EpiBrowser

Full name

Luciferin 4-monooxygenase      

Location in the cell

Cytoplasmic   Reliability : 1.522 Mitochondrial   Reliability : 1.272 Nuclear   Reliability : 1.486

CDS

ATGTACTGGGATGAGCACTTTTATTTTTACTTTGTAGAGCGACTAAAGCTGTTGATTCATTACAAGAATCATCAGATATCACCGCTTGAAATAGAGAAGGTCATTCGCCAGCATCCGGGTGTGTTGGACGTTATAGTCACCAGCATCACGGACGTCCAGCGCGAGGAGCTGCCGTGCGCTTGTGTCGTGCTTAAAGATGGACGTCGCGTCACCGAACAGGAAATCAAGGACTTGGTTCGAGATTCGCTAACGGATCCAAAACAATTGAGAGGTGGCGTTTTTTTCTTAAAGGAAATGCCCATGAACCCACAACTGAAAATCGACAGAAGAAAAATAAAAGAATTCGTTATTAATTCATTAGGCACAAAAAAATAA

Protein

MYWDEHFYFYFVERLKLLIHYKNHQISPLEIEKVIRQHPGVLDVIVTSITDVQREELPCACVVLKDGRRVTEQEIKDLVRDSLTDPKQLRGGVFFLKEMPMNPQLKIDRRKIKEFVINSLGTKK

Description

Produces green light with a wavelength of 562 nm.

Catalytic Activity

ATP + firefly D-luciferin + O2 = AMP + CO2 + diphosphate + firefly oxyluciferin + hnu

Cofactor

Mg(2+)

Similarity

Belongs to the ATP-dependent AMP-binding enzyme family.
Belongs to the peptidase S1 family.

Keywords

3D-structure   ATP-binding   Luminescence   Magnesium   Metal-binding   Monooxygenase   Nucleotide-binding   Oxidoreductase   Peroxisome   Photoprotein  

Feature

chain  Luciferin 4-monooxygenase

Uniprot

A0A0N1IQK8   A0A194PZY0   A0A194R6T5   A0A1B3TP04   A0A1B3TNX4   A0A1B3TNY4   + More
A0A2H1VFT6   A0A2W1C0Z5   A0A2A4JE16   A0A0L7LS68   A0A1B3TNZ3   A0A1B3TP14   A0A2W1BFJ2   A0A2A4JFU1   A0A1B3TNX9   A0A1B3TP12   A0A2A4JCF3   A0A1B3TNZ2   A0A1B3TNX2   A0A1B3TP25   A0A2W1BJK0   A0A1B3TP11   A0A1B3TP22   A0A3S2N8I8   A0A2H1V3V7   A0A1B3TNZ6   A0A2W1BLY3   A0A2A4J5M1   A0A194Q640   A0A1B3TP10   A0A1B3TNZ4   A0A212FBS4   A0A2H1VAR1   A0A2A4JDK9   A0A1B3TP07   A0A2H1VV91   A0A2A4JGT9   A0A2W1BJT9   A0A2H1WV86   A0A1B3TNX3   A0A2H1W204   A0A1B3TNY0   A0A194Q0P0   A0A1B3TNZ0   A0A0N1PKC2   A0A2A4J4G8   A0A1B3TNZ5   A0A194PZW6   A0A2W1BGF2   A0A1B3TNW9   A0A1B3TP01   A0A212FN15   A0A194Q1K5   A0A194R1K6   A0A194R232   A0A1B3TP24   A0A2H1V5T4   A0A2H1V0G3   A0A2H1V5V8   A0A2H1VH10   A0A2H1WMC6   A0A2T6WK65   A0A2A4JKH2   A0A2W1B861   A0A428D0L8   A0A2S3QZT6   D5MS63   A0A2A4JW63   A0A3R9K407   A0A3R9LF12   A0A0L7L495   H1AD93   A0A1L8DZ07   A0A2H1VW29   A0A2W1BC60   A0A194QZM0   A0A385I359   V9VFW4   Q3U139   A0A1E1J9G8   A3KBZ5   H1AD96   P08659   A0A1L8DY75   Q75ZG1   A0A2A4JUE1   A0A194R547   A0A194PUZ5   A3KBZ6   A3KBZ8   A0A3S2NR21   A3KBZ9   A3KBZ7   A0A1Q2T850   A0A1B3TNR9   A0A2H1VGY5   G9M6I9   A0A1Q2U2F7   A0A3F2YLV6  

EC Number

1.13.12.7

Pubmed

26354079    27553646    28756777    26227816    22118469    29358930    + More
20609019    30170542    10349636    11042159    11076861    11217851    12466851    16141073    28004739    3821727    3554235    8805533    9788915    12740604    15031779    28660982    30456363   

EMBL

LADJ01029118    KPJ21198.1    KQ459582    KPI98876.1    KQ460878    KPJ11571.1    + More
KU925757    AOG75382.1    KU925719    AOG75344.1    KU925729    AOG75354.1    ODYU01002332    SOQ39697.1    KZ149898    PZC78636.1    NWSH01001926    PCG69652.1    JTDY01000201    KOB78320.1    KU925742    AOG75367.1    KU925772    AOG75397.1    KZ150081    PZC73879.1    NWSH01001632    PCG70636.1    KU925730    AOG75355.1    KU925758    AOG75383.1    NWSH01001893    PCG69777.1    KU925733    AOG75358.1    KU925720    AOG75345.1    KU925774    AOG75399.1    PZC73875.1    KU925759    AOG75384.1    KU925773    AOG75398.1    RSAL01000205    RVE44356.1    ODYU01000351    SOQ34964.1    KU925747    AOG75372.1    PZC73876.1    NWSH01003054    PCG67036.1    KPI98875.1    KU925762    AOG75387.1    KU925743    AOG75368.1    AGBW02009293    OWR51173.1    ODYU01001291    SOQ37304.1    PCG69778.1    KU925761    AOG75386.1    ODYU01004651    SOQ44755.1    PCG70633.1    KZ150128    PZC73096.1    ODYU01011279    SOQ56917.1    KU925722    AOG75347.1    ODYU01005841    SOQ47125.1    KU925732    AOG75357.1    KPI98873.1    KU925745    AOG75370.1    KPJ21196.1    PCG67037.1    KU925746    AOG75371.1    KPI98872.1    PZC73878.1    KU925721    AOG75346.1    KU925744    AOG75369.1    AGBW02007648    OWR55128.1    KPI98874.1    KPJ11572.1    KPJ11574.1    KU925775    AOG75400.1    ODYU01000839    SOQ36210.1    ODYU01000111    SOQ34327.1    ODYU01000840    SOQ36211.1    ODYU01002515    SOQ40108.1    ODYU01009613    SOQ54167.1    PYJI01000254    PUE89139.1    NWSH01001271    PCG71900.1    KZ150230    PZC72009.1    RJNV01000052    RSI85664.1    PDGH01000119    POB45175.1    AB535101    BAJ07977.1    NWSH01000564    PCG75622.1    RJNQ01000038    RSI74579.1    RJPK01000016    RSJ67583.1    JTDY01003125    KOB70109.1    AB644225    BAL46509.1    GFDF01002418    JAV11666.1    ODYU01004634    SOQ44712.1    PZC72011.1    KQ460890    KPJ10988.1    MH759204    MH759205    MH759206    MH759207    AXY64450.1    KF713491    AHC94771.1    AK155098    AK156297    BAE33661.1    CALQ01001999    CCM20260.1    AB261982    BAF48390.1    MH759021    MH759022    MH759023    MH759024    MH759025    MH759026    MH759027    MH759028    MH759029    MH759030    MH759031    MH759032    MH759033    MH759034    MH759035    MH759036    MH759037    MH759038    MH759039    MH759040    MH759041    MH759042    MH759043    MH759044    MH759045    MH759046    MH759047    MH759048    MH759049    MH759050    MH759051    MH759052    MH759053    MH759054    MH759055    MH759056    MH759057    MH759058    MH759059    MH759060    MH759061    MH759062    MH759063    MH759064    MH759065    MH759066    MH759067    MH759068    MH759069    MH759070    MH759071    MH759072    MH759073    MH759074    MH759075    MH759076    MH759077    MH759078    MH759079    MH759080    MH759081    MH759082    MH759083    MH759084    MH759085    MH759086    MH759087    MH759088    MH759089    MH759090    MH759091    MH759092    MH759093    MH759094    MH759095    MH759096    MH759097    MH759098    MH759099    MH759100    MH759101    MH759102    MH759103    MH759104    MH759105    MH759106    MH759107    MH759108    MH759109    MH759110    MH759111    MH759112    MH759113    MH759114    MH759115    MH759116    MH759117    MH759118    MH759119    MH759120    MH759121    MH759122    MH759123    MH759124    MH759125    MH759126    MH759127    MH759128    MH759129    MH759130    MH759131    MH759132    MH759133    MH759134    MH759135    MH759136    MH759137    MH759138    MH759139    MH759140    MH759141    MH759142    MH759143    MH759144    MH759145    MH759146    MH759147    MH759148    MH759149    MH759150    MH759151    MH759152    MH759153    MH759154    MH759155    MH759156    MH759157    MH759158    MH759159    MH759160    MH759161    MH759162    MH759163    MH759164    MH759165    MH759166    MH759167    MH759168    MH759169    MH759170    MH759171    MH759172    MH759173    MH759174    MH759175    MH759176    MH759177    MH759178    MH759179    MH759180    MH759181    MH759182    MH759183    MH759184    MH759185    MH759186    MH759187    MH759188    MH759189    MH759190    MH759191    MH759192    MH759193    MH759194    MH759195    MH759196    MH759197    MH759198    MH759199    MH759200    MH759201    MH759202    MH759203    MH759208    MH759209    MH759210    AB644228    GEZM01002375    AXY64266.1    BAL46512.1    JAV97291.1    M15077    X84846    X84848    U03687    U89934    U89935    GFDF01002674    JAV11410.1    AB119282    BAD00047.1    PCG75621.1    KPJ10986.1    KQ459593    KPI96564.1    AB261983    BAF48391.1    AB261985    BAF48393.1    RSAL01000342    RVE42388.1    AB261986    BAF48394.1    AB261984    BAF48392.1    LC198321    BAW87787.1    KU670945    AOG75000.1    SOQ40110.1    AB604790    BAL40875.1    LC215694    BAW98153.1   

Proteomes

UP000053240    UP000053268    UP000218220    UP000037510    UP000283053    UP000007151    + More
UP000244733    UP000273339    UP000237466    UP000272928    UP000281558    UP000163705    UP000122913   

PRIDE

P08659   

Pfam

PF00501   AMP-binding        + More
PF04051   TRAPP
PF13193   AMP-binding_C
PF01636   APH
PF00089   Trypsin

Interpro

IPR016696   TRAPP-I_su5        + More
IPR007194   TRAPP_component       
IPR000873   AMP-dep_Synth/Lig       
IPR025110   AMP-bd_C       
IPR024096   NO_sig/Golgi_transp_ligand-bd       
IPR020845   AMP-binding_CS       
IPR042099   AMP-dep_Synthh-like_sf       
IPR027380   Luciferase-like_N_sf       
IPR024165   Kan/Strep_kinase       
IPR011009   Kinase-like_dom_sf       
IPR002575   Aminoglycoside_PTrfase       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR009003   Peptidase_S1_PA       
IPR001314   Peptidase_S1A       
IPR033116   TRYPSIN_SER       

SUPFAM

SSF111126   SSF111126        + More
SSF56112   SSF56112       
SSF50494   SSF50494       

Gene 3D

3.40.50.12780     4.10.8.10    

CDD

cd14943  TRAPPC5_Trs31
cd05150  APH
cd00190  Tryp_SPc

ProteinModelPortal

A0A0N1IQK8   A0A194PZY0   A0A194R6T5   A0A1B3TP04   A0A1B3TNX4   A0A1B3TNY4   + More
A0A2H1VFT6   A0A2W1C0Z5   A0A2A4JE16   A0A0L7LS68   A0A1B3TNZ3   A0A1B3TP14   A0A2W1BFJ2   A0A2A4JFU1   A0A1B3TNX9   A0A1B3TP12   A0A2A4JCF3   A0A1B3TNZ2   A0A1B3TNX2   A0A1B3TP25   A0A2W1BJK0   A0A1B3TP11   A0A1B3TP22   A0A3S2N8I8   A0A2H1V3V7   A0A1B3TNZ6   A0A2W1BLY3   A0A2A4J5M1   A0A194Q640   A0A1B3TP10   A0A1B3TNZ4   A0A212FBS4   A0A2H1VAR1   A0A2A4JDK9   A0A1B3TP07   A0A2H1VV91   A0A2A4JGT9   A0A2W1BJT9   A0A2H1WV86   A0A1B3TNX3   A0A2H1W204   A0A1B3TNY0   A0A194Q0P0   A0A1B3TNZ0   A0A0N1PKC2   A0A2A4J4G8   A0A1B3TNZ5   A0A194PZW6   A0A2W1BGF2   A0A1B3TNW9   A0A1B3TP01   A0A212FN15   A0A194Q1K5   A0A194R1K6   A0A194R232   A0A1B3TP24   A0A2H1V5T4   A0A2H1V0G3   A0A2H1V5V8   A0A2H1VH10   A0A2H1WMC6   A0A2T6WK65   A0A2A4JKH2   A0A2W1B861   A0A428D0L8   A0A2S3QZT6   D5MS63   A0A2A4JW63   A0A3R9K407   A0A3R9LF12   A0A0L7L495   H1AD93   A0A1L8DZ07   A0A2H1VW29   A0A2W1BC60   A0A194QZM0   A0A385I359   V9VFW4   Q3U139   A0A1E1J9G8   A3KBZ5   H1AD96   P08659   A0A1L8DY75   Q75ZG1   A0A2A4JUE1   A0A194R547   A0A194PUZ5   A3KBZ6   A3KBZ8   A0A3S2NR21   A3KBZ9   A3KBZ7   A0A1Q2T850   A0A1B3TNR9   A0A2H1VGY5   G9M6I9   A0A1Q2U2F7   A0A3F2YLV6  

PDB

4G36     E-value=3.39907e-26,     Score=287

KEGG

101735928    no KO assigned | (RefSeq) luciferin 4-monooxygenase-like

GO

GO:0003824   GO:0030008   GO:0048193   GO:0004497   GO:0016021   GO:0102391   GO:0004467   GO:0003996   GO:0046872   GO:0051087   GO:0047077   GO:0005777   GO:0005524   GO:0008218   GO:0016773   GO:0046677   GO:0004252  

PANTHER

PTHR20902  

Subcellular location

Peroxisome  

Length:

124

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00027

Exp number, first 60 AAs:

0.00027

Total prob of N-in:

0.17502

outside

1  -  124

 

 

Pi

223.126929

Theta

154.506703

Tajima's D

1.369269

CLR

0.060807

CSRT

0.760161991900405

Interpretation

Uncertain