Gene

KWMTBOMO09692

Pre Gene Modal

BGIBMGA012880

Annotation

PREDICTED:_transcription_initiation_protein_SPT3_homolog_[Amyelois_transitella]

Location

Bomo_Chr16(+):7026002-7027065      View in EpiBrowser

Full name

Transcription initiation protein SPT3 homolog      

Alternative Name

SPT3-like protein

Location in the cell

Nuclear   Reliability : 2.256

CDS

ATGACTTACTATACTATGGAAACATGTGGAGAAGGGACGAACTTTCAAAAAGAAATATCGAACATGATGCACGGATTTGGAGATAACCCGAACCCTAACGCTGCAACGGTACTTTTAGTAGAAAATATTGTTTTGCAACAGCTTAGGAGTATCCTACAAGAAGGAATATTTAATTCTAACTTGAGAGGAAGTAAAACAATCACTAACTACGACATAATATACACAATGCGTAACAATACTGTAAAATTAAAACGTTTGCACGATTACCAGCAAAAACTGGATCAAATCGACAACAAATCACAAGTAAACGTCACAACATCAGCCGAAACTATATACTCTAATATTATACTAGAAGACGAGAAGGATCCGACAATGAAAAAAAAGAGAACACATATTGATGTGATAAAACTAATAGACGAAGCTGATGAAGTGAGTCAGATAAAATTCGATGCGATCGATTACTTAAGGAAAGTGCGAGCTTCGAAATTAACAGAGTCAATGTCTTTTGAAAAGTATGAAGCCTATCATAAAGCTAGATGTAGTTCTTTCCGTTGCAATGGCTATGGAATCGGTAAAGGCTTTATAAAATTAGAAAGGTGGATCAATCCAACCAAGGAACTCAAAATTAGTCACTCGGCATTAGAAGTATTGTGTTTTATTGCTTACGAAACTGTGGCTGAAATTGTTGATGCTGTGTATTTGATTCGACAAGATGCCAAAAGGAAACACGGAGACCCTTTTAGTAAATATGAAGGTGGATATTTCTGTAATCCCTTAAGCTTAAGTAATGCTGTTTATATAAAGTCAGGTTATGAAGGAGTGCCTGCAATAACAGTGGCTGAAGTGAGAGAGGCATTGCGTCGTTACTTTTGTCCTATAAATGGAATGAATGGATTATTTTATAGAAATATGCACATGGACTTACCAGCAAGATTTATTGCTTTATAA

Protein

MTYYTMETCGEGTNFQKEISNMMHGFGDNPNPNAATVLLVENIVLQQLRSILQEGIFNSNLRGSKTITNYDIIYTMRNNTVKLKRLHDYQQKLDQIDNKSQVNVTTSAETIYSNIILEDEKDPTMKKKRTHIDVIKLIDEADEVSQIKFDAIDYLRKVRASKLTESMSFEKYEAYHKARCSSFRCNGYGIGKGFIKLERWINPTKELKISHSALEVLCFIAYETVAEIVDAVYLIRQDAKRKHGDPFSKYEGGYFCNPLSLSNAVYIKSGYEGVPAITVAEVREALRRYFCPINGMNGLFYRNMHMDLPARFIAL

Description

Probable transcriptional activator.

Subunit

Component of the PCAF complex, at least composed of TADA2L/ADA2, SUPT3H, TADA3L/ADA3, TAF5L/PAF65-beta, TAF6L/PAF65-alpha, TAF10/TAFII30, TAF12/TAFII20, TAF9/TAFII31 and TRRAP. Associates with TAFII31 and GCN5L2. Component of the TFTC-HAT complex, at least composed of TAF5L, TAF6L, TADA3L, SUPT3H/SPT3, TAF2/TAFII150, TAF4/TAFII135, TAF5/TAFII100, GCN5L2/GCN5, TAF10 and TRRAP. Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9. The STAGA core complex is associated with a subcomplex required for histone deubiquitination composed of ATXN7L3, ENY2 and USP22.

Similarity

Belongs to the SPT3 family.

Keywords

Acetylation   Activator   Alternative splicing   Complete proteome   Direct protein sequencing   Isopeptide bond   Nucleus   Polymorphism   Reference proteome   Transcription   Transcription regulation   Ubl conjugation  

Feature

chain  Transcription initiation protein SPT3 homolog
splice variant  In isoform 2.
sequence variant  In dbSNP:rs16872923.

Uniprot

H9JTL8   A0A1E1WSF9   A0A194R1C3   A0A2A4JD18   S4PY51   A0A2H1VIX2   + More
A0A212FN00   A0A0L7L2A4   A0A0L7LG43   A0A0L7L263   A0A1W4WUS4   D6WHX1   A0A0N0BKJ7   K7IP16   A0A2P8XS51   A0A232EUT9   A0A026WUS6   A0A293MT60   A0A2R5LD81   A0A0C9QSG8   A0A067RI08   A0A0L7QMR3   A0A154PF75   L7LQW8   E2A273   A0A1Z5L1F1   E2BNL7   A0A0J7K4Y7   G3MI98   A0A2K5ERL1   A0A224Z8T2   A0A2K6KKH5   A0A2K6NBV1   A0A2K5I8S4   A0A151IVP8   G1T7P0   E9IWP1   K7DEW9   A0A2J8Y4X1   G3RFB2   A0A024RD67   O75486   A0A2I3HJM7   A0A2K5ZLH1   A0A2K6V6B1   A0A2K6BFJ1   A0A158NN48   A0A2K5LG50   A0A2K5UI13   A0A2I3LH29   H9G0V2   A0A195FGS8   A0A131YW77   A0A182YJC1   Q5U608   U3D6N9   A0A023GML6   F4X369   A0A2R9AIQ8   A0A340XGK0   M3WBP7   A0A182WEJ1   A0A195BET6   A0A1E1X3Z4   A0A3B1KG57   A0A0P4W7L0   U5EGB3   N6T5T7   T1KYN1   A0A1S3FDC8   A0A2K6EMP3   A0A0P6J671   A0A182M2Q8   A0A182R6Z9   A0A084VID8   A0A2D4JV86   G3UR77   A0A3B3T3S8   A0A182PC97   A0A2D4I4Z9   A0A182J891   Q5ZIW0   A0A3Q2UIL6   A0A2A3EEV6   A0A2M4AY25   G5BNF1   A0A2R8MX91   A0A2U4BIY3   I3MPQ3   A0A151IKZ8   W5JVU5   A0A2Y9JIB1   A0A452J2P7   A0A182XKL5   A0A182VDM6   A0A182L4B0   A0A182TN70   A0A182HGX0  

Pubmed

19121390    26354079    23622113    22118469    26227816    18362917    + More
19820115    20075255    29403074    28648823    24508170    30249741    24845553    25576852    20798317    28528879    22216098    28797301    25362486    21993624    21282665    16136131    22398555    11181995    9787080    9674425    9726987    14702039    14574404    15489334    9885574    10373431    11564863    18206972    22814378    25218447    28112733    21347285    17431167    25319552    26830274    25244985    25243066    21719571    22722832    17975172    28503490    25329095    23537049    24438588    20838655    29240929    15592404    15642098    21993625    20920257    23761445    28562605    20966253   

EMBL

BABH01003606    GDQN01001089    JAT89965.1    KQ460878    KPJ11593.1    NWSH01002011    + More
PCG69444.1    GAIX01003898    JAA88662.1    ODYU01002820    SOQ40777.1    AGBW02007649    OWR55122.1    JTDY01003417    KOB69587.1    JTDY01001211    KOB74523.1    KOB69588.1    KQ971321    EFA00044.2    KQ435698    KOX80692.1    PYGN01001454    PSN34744.1    NNAY01002091    OXU22103.1    KK107106    QOIP01000002    EZA59416.1    RLU26132.1    GFWV01019264    MAA43992.1    GGLE01003181    MBY07307.1    GBYB01006679    JAG76446.1    KK852669    KDR18882.1    KQ414885    KOC59885.1    KQ434892    KZC10536.1    GACK01010618    JAA54416.1    GL435922    EFN72478.1    GFJQ02005764    JAW01206.1    GL449414    EFN82796.1    LBMM01014287    KMQ85246.1    JO841599    AEO33216.1    GFPF01012167    MAA23313.1    KQ980895    KYN11751.1    AAGW02018051    AAGW02018052    AAGW02018053    AAGW02018054    AAGW02018055    AAGW02018056    AAGW02018057    AAGW02018058    AAGW02018059    AAGW02018060    GL766597    EFZ14990.1    AACZ04022891    AACZ04022892    AACZ04022893    AACZ04022894    AACZ04022895    AACZ04022896    AACZ04022897    GABC01002300    GABF01010021    GABD01010751    GABE01005295    NBAG03000221    JAA09038.1    JAA12124.1    JAA22349.1    JAA39444.1    PNI77556.1    PNI77558.1    ABGA01248159    ABGA01248160    ABGA01248161    ABGA01248162    ABGA01248163    ABGA01248164    ABGA01248165    ABGA01248166    ABGA01248167    ABGA01248168    NDHI03003283    PNJ89325.1    PNJ89327.1    CABD030044832    CABD030044833    CABD030044834    CABD030044835    CABD030044836    CABD030044837    CABD030044838    CABD030044839    CABD030044840    CABD030044841    CH471081    EAX04276.1    AF064804    AF069734    AF073930    AK313874    AL096865    AL138880    AL161905    AL360272    AL499610    BC050384    ADFV01032095    ADFV01032096    ADFV01032097    ADFV01032098    ADFV01032099    ADFV01032100    ADFV01032101    ADFV01032102    ADFV01032103    ADFV01032104    ADTU01000299    ADTU01000300    AQIA01051756    AQIA01051757    AQIA01051758    AQIA01051759    AQIA01051760    AQIA01051761    AQIA01051762    AHZZ02024703    AHZZ02024704    AHZZ02024705    AHZZ02024706    AHZZ02024707    JSUE03030958    JSUE03030959    JSUE03030960    JSUE03030961    JSUE03030962    JSUE03030963    JSUE03030964    JU336758    JU477522    JV048467    AFE80511.1    AFH34326.1    AFI38538.1    KQ981606    KYN39581.1    GEDV01005350    JAP83207.1    BC035816    AAH35816.1    GAMS01002775    GAMR01008008    GAMP01010164    JAB20361.1    JAB25924.1    JAB42591.1    GBBM01001298    JAC34120.1    GL888609    EGI59050.1    AJFE02119515    AJFE02119516    AJFE02119517    AJFE02119518    AJFE02119519    AJFE02119520    AJFE02119521    AJFE02119522    AJFE02119523    AJFE02119524    AANG04003966    KQ976509    KYM82680.1    GFAC01005203    JAT93985.1    GDRN01076373    JAI62903.1    GANO01003514    JAB56357.1    APGK01043031    KB741011    KB631636    KI209682    ENN75554.1    ERL84883.1    ERL96074.1    CAEY01000714    GEBF01003892    JAN99740.1    AXCM01001816    ATLV01013353    KE524854    KFB37732.1    IACL01015259    IACL01015260    LAB00378.1    IACK01081177    IACK01081181    LAA79303.1    AADN05001052    AJ720674    CAG32333.1    KZ288266    PBC30267.1    GGFK01012372    MBW45693.1    JH171133    EHB10892.1    AGTP01010763    AGTP01010764    AGTP01010765    AGTP01010766    AGTP01010767    AGTP01010768    AGTP01010769    AGTP01010770    AGTP01010771    AGTP01010772    KQ977151    KYN05286.1    ADMH02000317    ETN67004.1    APCN01002367   

Proteomes

UP000005204    UP000053240    UP000218220    UP000007151    UP000037510    UP000192223    + More
UP000007266    UP000053105    UP000002358    UP000245037    UP000215335    UP000053097    UP000279307    UP000027135    UP000053825    UP000076502    UP000000311    UP000008237    UP000036403    UP000233020    UP000233180    UP000233200    UP000233080    UP000078492    UP000001811    UP000002277    UP000001595    UP000001519    UP000005640    UP000001073    UP000233140    UP000233220    UP000233120    UP000005205    UP000233060    UP000233100    UP000028761    UP000006718    UP000078541    UP000076408    UP000008225    UP000007755    UP000240080    UP000265300    UP000011712    UP000075920    UP000078540    UP000018467    UP000019118    UP000030742    UP000015104    UP000081671    UP000233160    UP000075883    UP000075900    UP000030765    UP000001645    UP000261540    UP000075885    UP000075880    UP000000539    UP000242457    UP000006813    UP000245320    UP000005215    UP000078542    UP000000673    UP000248482    UP000291020    UP000076407    UP000075903    UP000075882    UP000075902    UP000075840   

PRIDE

H9JTL8    A0A024RD67    O75486    Q5U608    Q5ZIW0   

Pfam

PF02269   TFIID-18kDa        + More
PF10447   EXOSC1
PF14382   ECR1_N
PF00096   zf-C2H2
PF00067   p450

Interpro

IPR003195   TFIID_TAF13        + More
IPR009072   Histone-fold       
IPR039771   Csl4       
IPR025721   Exosome_cplx_N_dom       
IPR019495   EXOSC1_C       
IPR012340   NA-bd_OB-fold       
IPR036236   Znf_C2H2_sf       
IPR012934   Znf_AD       
IPR013087   Znf_C2H2_type       
IPR001128   Cyt_P450       
IPR036396   Cyt_P450_sf       

SUPFAM

SSF47113   SSF47113        + More
SSF50249   SSF50249       
SSF57667   SSF57667       
SSF48264   SSF48264       

Gene 3D

1.10.20.10     1.10.630.10    

CDD

cd07978  TAF13

ProteinModelPortal

H9JTL8   A0A1E1WSF9   A0A194R1C3   A0A2A4JD18   S4PY51   A0A2H1VIX2   + More
A0A212FN00   A0A0L7L2A4   A0A0L7LG43   A0A0L7L263   A0A1W4WUS4   D6WHX1   A0A0N0BKJ7   K7IP16   A0A2P8XS51   A0A232EUT9   A0A026WUS6   A0A293MT60   A0A2R5LD81   A0A0C9QSG8   A0A067RI08   A0A0L7QMR3   A0A154PF75   L7LQW8   E2A273   A0A1Z5L1F1   E2BNL7   A0A0J7K4Y7   G3MI98   A0A2K5ERL1   A0A224Z8T2   A0A2K6KKH5   A0A2K6NBV1   A0A2K5I8S4   A0A151IVP8   G1T7P0   E9IWP1   K7DEW9   A0A2J8Y4X1   G3RFB2   A0A024RD67   O75486   A0A2I3HJM7   A0A2K5ZLH1   A0A2K6V6B1   A0A2K6BFJ1   A0A158NN48   A0A2K5LG50   A0A2K5UI13   A0A2I3LH29   H9G0V2   A0A195FGS8   A0A131YW77   A0A182YJC1   Q5U608   U3D6N9   A0A023GML6   F4X369   A0A2R9AIQ8   A0A340XGK0   M3WBP7   A0A182WEJ1   A0A195BET6   A0A1E1X3Z4   A0A3B1KG57   A0A0P4W7L0   U5EGB3   N6T5T7   T1KYN1   A0A1S3FDC8   A0A2K6EMP3   A0A0P6J671   A0A182M2Q8   A0A182R6Z9   A0A084VID8   A0A2D4JV86   G3UR77   A0A3B3T3S8   A0A182PC97   A0A2D4I4Z9   A0A182J891   Q5ZIW0   A0A3Q2UIL6   A0A2A3EEV6   A0A2M4AY25   G5BNF1   A0A2R8MX91   A0A2U4BIY3   I3MPQ3   A0A151IKZ8   W5JVU5   A0A2Y9JIB1   A0A452J2P7   A0A182XKL5   A0A182VDM6   A0A182L4B0   A0A182TN70   A0A182HGX0  

PDB

6MZL     E-value=0.00519473,     Score=93

KEGG

101745291    K11313 transcription initiation protein SPT3 | (RefSeq) transcription initiation protein SPT3 homolo

GO

GO:0006366   GO:0046982   GO:0003712   GO:0003677   GO:0005669   GO:0006357   GO:0016740   GO:0033276   GO:0016578   GO:0004402   GO:0043966   GO:0030914   GO:0003713   GO:0005654   GO:0005634   GO:0006355   GO:0045893   GO:0003723   GO:0000178   GO:0006396   GO:0003743   GO:0008270   GO:0003676   GO:0005506   GO:0016705   GO:0020037   GO:0051259   GO:0008449   GO:0030203   GO:0006730   GO:0009258   GO:0016155   GO:0003824  

PANTHER

PTHR11380   PTHR12686  

Subcellular location

Nucleus  

Length:

315

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.18369

Exp number, first 60 AAs:

0.00329

Total prob of N-in:

0.07175

outside

1  -  315

 

 

Pi

287.256169

Theta

212.839416

Tajima's D

1.100805

CLR

0

CSRT

0.690565471726414

Interpretation

Uncertain