Gene

KWMTBOMO09690

Annotation

PREDICTED:_trypsin?_alkaline_C-like_[Amyelois_transitella]

Location

Bomo_Chr16(-):7016207-7019891      View in EpiBrowser

Full name

Trypsin, alkaline A       + More
Trypsin CFT-1      
Trypsin, alkaline C      

Location in the cell

Extracellular   Reliability : 2.623

CDS

ATGTTTTTTAAATGTTTAAATTCTGTAGTTGCGGTTTTTTTAACTTTTGAAATTTGTCAAGTAAATACACAGTATCAACTGCGAGTGATCGAAGGAAAGCCCACCTCTATAGACAGATACCCGATAGTTGCACAGCTGTTGCTAGATACGTGGGGCGACAGAAACTTTATACAGCACTGTGCAGGTGTTATCCTAACATCTAGGCATGTCGTATCCACTGCACACTGTTTTCAATACAACGAAAGTACCGGAAGAAACTACAGTCTACCTAAATACTGGAGGGTTCGCGTAGGTTCCTCTTACAGGTCCCGAGGAGGTTTCATCCATGGGTTGAAAACAATCATAACTCATCGCGGCTTCGATCAGCTTTATTACACCAATGATATCGCAATGGTCGTTGTGACTAAAACATTTATATTTAGTCCAAAAGTAAGACAAGGAACTATTGTGAAGTATGGAACCGAAATAAGTCCGAATTCTATTTGTACCCTTATCGGATGGGGAGTTAAAGAGCCTGACGGAGCTCAACCGGAACAATTGCAAAGCACAGCACTATTTACAATAGATCAAGATGTGTGTAGAAATCGTTACGCCACAATCCGGGCACTGATTTCTGATTCAATGTTATGTGCTGGACGCGTTGAAGCTGGCGGTCCTGATGGTTGCTATGGAGACTCTGGTGGGCCAATAATATACAAAGGCCTTGTAGTAGGCCTCGTATCTTTCGGTTACTCTTGCGGTCATCGATACTACCCTGGTGTCTACACTAAAATCTCTCATTATACAGATTGGATAGTAAAAACAGTTTTGACTAATAAATAA

Protein

MFFKCLNSVVAVFLTFEICQVNTQYQLRVIEGKPTSIDRYPIVAQLLLDTWGDRNFIQHCAGVILTSRHVVSTAHCFQYNESTGRNYSLPKYWRVRVGSSYRSRGGFIHGLKTIITHRGFDQLYYTNDIAMVVVTKTFIFSPKVRQGTIVKYGTEISPNSICTLIGWGVKEPDGAQPEQLQSTALFTIDQDVCRNRYATIRALISDSMLCAGRVEAGGPDGCYGDSGGPIIYKGLVVGLVSFGYSCGHRYYPGVYTKISHYTDWIVKTVLTNK

Catalytic Activity

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Similarity

Belongs to the peptidase S1 family.

Keywords

Disulfide bond   Hydrolase   Protease   Secreted   Serine protease   Signal   Zymogen   Direct protein sequencing  

Feature

propeptide  Activation peptide
chain  Trypsin, alkaline A

Uniprot

A0A2H1VIX1   A0A194PZV2   A0A194R252   A0A212FMZ9   A0A2A4JDE7   A0A437B8S1   + More
A0A0L7L2M0   A0A3S2TNU2   A0A194PNR3   A0A194PQQ5   A0A194PVB6   A0A212FL72   A0A0M4M544   A0A194PNR6   G9F9K6   A0A2A4K6F3   A0A194PP33   A0A0N1I947   A0A3S2P336   A0A194PQ27   A0A2W1BKV8   B4X995   A0A2A4K5G7   A0A2W1BKF9   A0A2A4K6E9   V9M0R7   J7IJ83   I3UII8   I7DEI4   A0A0N1PHJ0   A0A0L7LAY9   B4X996   A0A089Q9M3   Q9NB92   O18447   Q4L1K1   A0A2A4K6W3   A0A0L7KYH0   A0A1C9M3A1   A0A2A4JCA8   A0A194PQQ0   A0A2A4K648   C9W8F7   B4X9A1   B3F884   A0A0K0Q498   A0A1E1WDA8   Q56IB6   T1QDI0   C9W8I2   A0A2A4K747   C4PFX2   V9LL27   Q56IB4   Q6R561   A0A437BL04   O18436   A0A2W1BQW9   O62598   Q56IB5   A0A2W1B1G1   A0A1B0RHN7   O18434   P35045   A0A2W1BKR8   A0A2U8NFD7   A0A1E1WNA7   A0A2H1V0M1   Q56IB7   A0A2W1BL45   B4X9A0   O76954   A0A410KK63   Q2I0D8   I7D523   Q4L1K6   A0A194QET8   P35042   Q27540   P35047   A0A194QD45   J7IF09   O18435   Q56IB8   Q961Y0   A0A2H1VJ41   A0A194QD40   J7IFG7   A0A2W1BP39   A0A2A4K5I4   O18441   A0A437BTC7   A0A2A4JRB9   Q4L1M0   B4X998   B4X999   A0A2A4K6F8   A0A089QDA2   A0A0K8SII3   A9P3S8  

EC Number

3.4.21.4

Pubmed

26354079    22118469    26227816    22432944    28756777    23247047    + More
22824002    11267903    9404008    15979001    20824821    16469064    23955944    20545748    15944081    19146482    10672067    8205142    8294037    8353523    7550246    12110299   

EMBL

ODYU01002820    SOQ40778.1    KQ459582    KPI98851.1    KQ460878    KPJ11594.1    + More
AGBW02007649    OWR55124.1    NWSH01002011    PCG69442.1    RSAL01000115    RVE46900.1    JTDY01003417    KOB69586.1    RSAL01000038    RVE51123.1    KQ459597    KPI95066.1    KPI95074.1    KPI95070.1    AGBW02007905    OWR54439.1    KR024672    ALE15214.1    KPI95071.1    JN033751    JN315765    AEW46904.1    AFK64829.1    NWSH01000106    PCG79484.1    KPI95067.1    KQ460226    KPJ16474.1    RVE51121.1    KPI95068.1    KZ149992    PZC75528.1    EF531631    EF531633    ABR88242.1    ABR88244.1    PCG79485.1    PZC75529.1    PCG79488.1    JX866720    AGB93875.1    JX195651    AFQ37934.1    JN315762    AFK64826.1    JN793539    AFO68319.1    KPJ16473.1    JTDY01001906    KOB72570.1    EF531632    ABR88243.1    KM083778    AIR09759.1    AF261970    AAF74732.1    HM209426    Y12283    KZ150104    ADI32887.1    CAA72962.1    PZC73444.1    AY587164    AAT95356.1    PCG79493.1    JTDY01004416    KOB68185.1    KU302250    AOQ30448.1    NWSH01002022    PCG69396.1    KPI95069.1    PCG79486.1    FJ205402    ACR15970.1    EF531637    ABR88248.1    EF635223    ABU96714.1    KP730443    AKR06191.1    GDQN01010607    GDQN01006137    JAT80447.1    JAT84917.1    AY953061    AAX62034.1    JQ429438    AFW03963.1    FJ205428    ACR15995.1    PCG79472.1    FJ940726    ODYU01006287    ACR25157.1    SOQ47996.1    JQ340915    AFP74111.1    AY953063    AAX62036.1    AY513649    AAR98918.1    RVE51124.1    EF104916    Y12271    ABP96918.1    CAA72950.1    PZC75527.1    AF064525    AF064526    AAC36247.1    AAC36248.1    AY953062    AAX62035.1    KZ150747    PZC70338.1    KM360188    AKH49604.1    Y12269    CAA72948.1    PZC73449.1    L16805    PZC73446.1    MF407317    AWL83213.1    GDQN01002626    JAT88428.1    ODYU01000133    SOQ34395.1    AY953060    AAX62033.1    PZC73450.1    EF531636    ABR88247.1    PCG79483.1    AJ007706    CAA07611.1    MH201548    QAR48641.1    DQ356009    ABC87051.1    JN793545    AFO68325.1    AY587159    AAT95351.1    KQ459167    KPJ03460.1    L04749    U12917    AAA84423.1    L16807    KPJ03463.1    JX195649    AFQ37932.1    Y12270    CAA72949.1    AY953059    AAX62032.1    AY040819    AAK81696.1    ODYU01002655    SOQ40442.1    KPJ03458.1    JX195652    AFQ37935.1    PZC73443.1    PCG79487.1    Y12276    CAA72955.1    PZC70339.1    RSAL01000013    RVE53439.1    NWSH01000830    PCG73960.1    AY587145    AAT95360.1    EF531634    ABR88245.1    EF531635    ABR88246.1    PCG79498.1    KM083777    AIR09758.1    GBRD01013231    JAG52595.1    EF104917    ABP96919.1   

Proteomes

UP000053268    UP000053240    UP000007151    UP000218220    UP000283053    UP000037510    + More

PRIDE

P35045    P35042    P35047   

Pfam

PF00089   Trypsin        + More
PF00226   DnaJ
PF07743   HSCB_C

Interpro

IPR001314   Peptidase_S1A        + More
IPR004640   HscB       
IPR009003   Peptidase_S1_PA       
IPR018114   TRYPSIN_HIS       
IPR036386   HscB_C_sf       
IPR001254   Trypsin_dom       
IPR001623   DnaJ_domain       
IPR033116   TRYPSIN_SER       
IPR036869   J_dom_sf       
IPR009073   HscB_oligo_C       

SUPFAM

SSF50494   SSF50494        + More
SSF46565   SSF46565       
SSF47144   SSF47144       

Gene 3D

1.10.287.110     1.20.1280.20    

CDD

cd00190  Tryp_SPc
cd06257  DnaJ

ProteinModelPortal

A0A2H1VIX1   A0A194PZV2   A0A194R252   A0A212FMZ9   A0A2A4JDE7   A0A437B8S1   + More
A0A0L7L2M0   A0A3S2TNU2   A0A194PNR3   A0A194PQQ5   A0A194PVB6   A0A212FL72   A0A0M4M544   A0A194PNR6   G9F9K6   A0A2A4K6F3   A0A194PP33   A0A0N1I947   A0A3S2P336   A0A194PQ27   A0A2W1BKV8   B4X995   A0A2A4K5G7   A0A2W1BKF9   A0A2A4K6E9   V9M0R7   J7IJ83   I3UII8   I7DEI4   A0A0N1PHJ0   A0A0L7LAY9   B4X996   A0A089Q9M3   Q9NB92   O18447   Q4L1K1   A0A2A4K6W3   A0A0L7KYH0   A0A1C9M3A1   A0A2A4JCA8   A0A194PQQ0   A0A2A4K648   C9W8F7   B4X9A1   B3F884   A0A0K0Q498   A0A1E1WDA8   Q56IB6   T1QDI0   C9W8I2   A0A2A4K747   C4PFX2   V9LL27   Q56IB4   Q6R561   A0A437BL04   O18436   A0A2W1BQW9   O62598   Q56IB5   A0A2W1B1G1   A0A1B0RHN7   O18434   P35045   A0A2W1BKR8   A0A2U8NFD7   A0A1E1WNA7   A0A2H1V0M1   Q56IB7   A0A2W1BL45   B4X9A0   O76954   A0A410KK63   Q2I0D8   I7D523   Q4L1K6   A0A194QET8   P35042   Q27540   P35047   A0A194QD45   J7IF09   O18435   Q56IB8   Q961Y0   A0A2H1VJ41   A0A194QD40   J7IFG7   A0A2W1BP39   A0A2A4K5I4   O18441   A0A437BTC7   A0A2A4JRB9   Q4L1M0   B4X998   B4X999   A0A2A4K6F8   A0A089QDA2   A0A0K8SII3   A9P3S8  

PDB

5CE1     E-value=2.96922e-15,     Score=198

KEGG

101737824    no KO assigned | (RefSeq) trypsin, alkaline A-like

GO

GO:0097428   GO:0001671   GO:0051259   GO:0004252   GO:0051087   GO:0008236   GO:0005615   GO:0006508   GO:0008484   GO:0008449   GO:0030203   GO:0003723   GO:0006730   GO:0009258   GO:0016155   GO:0003824  

PANTHER

PTHR14021  

Subcellular location

  

SignalP

Position:   1 - 23,         Likelihood:  0.739984

 

 

Length:

273

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.76587

Exp number, first 60 AAs:

0.15257

Total prob of N-in:

0.02967

outside

1  -  273

 

 

Pi

283.209746

Theta

171.294921

Tajima's D

1.870229

CLR

0.270498

CSRT

0.861806909654517

Interpretation

Uncertain