Gene

KWMTBOMO09647  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012974

Annotation

PREDICTED:_condensin_complex_subunit_3_[Amyelois_transitella]

Location

Bomo_Chr16(-):6116064-6151757      View in EpiBrowser

Full name

Condensin complex subunit 3      

Alternative Name

Chromosome assembly protein xCAP-G
Chromosome-associated protein G
Condensin subunit CAP-G
Non-SMC condensin I complex subunit G

Location in the cell

Nuclear   Reliability : 3.188

CDS

ATGGCTCCGACGGATGCTGAGATACCGACCACTGTACTGTCTTCTAGACCAAACCCGCGAAACAATCCGATAATGTTCAAAATATTTCAAAACGTCCAATTTAATGTTGTACAACACAAGAAATATGTTAAAGAAATGAGTAAACTATATAGAAAGTTAGATGAAGAATCATTCCGTGAAAGTTTCAAAAATGCCCTTATGTATCTGTTTACTTTTGGGGATACAAGTGCTAATGTTGATCGTGTAATACAGTTTGTGGCTACATTTTGTACTTCTCTAAATGATGAAGAGGAATTCTTGCTGTTTATCTTTGAAGTAATATTTGATTGTCAATGTGTTTCTGGACAATCTGTCAGGTATAGAGCCAGTCAGTTGCTGGCAGCCGTATTAGCTGCTCTTGGTGAAGATGCTTCTCTTGATGATGATTTGTGTGATAAGCTTCTTGCGTCACAGATGCAAAGGCTTCAAGACACTCGTGGGGCAGTACGTTGCCGCGCTGCTTTGGCTCTTCAACGTCTACAAAACCCAATGGAGCCCGACGATGAAGTCACCAGAGCCTACCGTTTTCACATGAGCTGTGACCCTAGCTCTTCAGTAAGAAGAGCTGTAGTCATGTCAATAGCCAAATGCACTCGAAACGTACCATTTGTGTTAGAACGTCTGTGTGACGTCGATGAGGCCGTACGACGTGCTGCATTCTTGTATATAGCAGCACTAAATGTAACACAGCTTCGCGTTAGACAAAGGGTTTTGACACTAAAGGTCGGCCTAACAGAGCGTTCCGTTCGAGTTCGGCGCGTTGTTGAAGAAATATTGATTCCGAGCTGGCTAAGCTCCTTTCAAGGGAACATCATACATCTACTAAAAGCTATACGGTTAGACAATGCCCACGACGCCAAAGACTCCCAATACGTAGCCGGTAAACTTCTGGAGTCTTTGTTTAAGCGACTTCCCATCTCGGAACTTCTAGAATGGTTACCAACAGAGAAGAATTTACGATTAATACCAGCGGACAAGCTGAACAAGGAAACCGCTTGGTACTGGCGACACCTGACCGAGCACTTGCAGAAAATCGACGACGACGAGACCCTGGAGACCATACTGCCGGACCTCGTTGTGCTCACTGGCTATATAAGAGCTATCGTAGAATCACCGTGCCCGTCTGAAAGCGAAGACCCCGTGGGGTTCAGCACGCGGCAGTACGTGCTGCACGAGCTGGGCAGCTTGCTGCGGGCATACGACGCGACCGACCCCGCGGGCCGGGTCGCCCTTCAAGCACTCGTCACTGACGTTCTCACCGGTGACTACGGTCCACTGTGTTCGGACGTGATCCGCGCACTAGTGGCAGCTTTAGAACTGGTCGTGCCCGAAGTGTCTCCTCGCATGGAGGTCATCAGCGGCGTCATATCCGCCTTACGGGATCCTCCGGAAACGGAAGCGCCCCCTATTATACCTCCACCGGCCGTTGACACTAACGAAATGAAATTACAGCGAGCAAGACTTCGTGTTTCACTGAACGTGGCAATGGAAGCACAGGAAGAAGCTGTAAAAGATCAGAACTACAGCCTCGCGGCCCAGTGTAAGGCTAAGGTAGAAGACATACAAAAGAAACTGGAAGAATTGAACATACAACCAACGCCGCCTCCCCCAGCAGCACCGACGATAAGAGAGAAGCTGTCGGATGCCGCGACTCTGAACAAATGCCTCACGATACTGAACAGCGCCCTCGACACGCCACAACTGCAAACCGTCACACCGATGCTGAGAATGATCTTCAATGAGTTGGAGGTCGAGATCTTTCAAAATCCCGAAATAATCGAAACGGCTTTGGAGACTGTAGCTTTATTCGGTATATTAGACAAGGAATTCGCCAAAGAAAACAAATCATTCTTCTTTGCAAACTTGATAGACACTTCAAACGAAACCGTCGTATCGACAGTGCTGAAGTGCATAGTGGATTTACTATGCGTGCACGGCGCTAAGGTGTTCGAGGACGAAGCGACGGAGCTGACCTGTGACGTCACCGACTCTGCGAATGCCTCACGAAAACGGAGCACGTATATAGATGCTATTGATGACGAAGGGAATATATCAGAGTCAGCGATATCAATGTCACCGAATCACAGCACCGTCATAGAACTGCTTCTGAAGATTATGGACAGCGCATGCGCCGCATACAGATTGATTATAGTGGAAGGGATGTGCCGCCTTCTACACTTAGGTCATTTAGAATCACCGGCGATTCTTAGCAGACTACTGTTGCTATGGTTCAACCCTGCTACGGTCGATGAAGATATGCTTCGTCAAACAATCGGGGTGTTCTTCCAAACGTTTCCAATGTGCGTTGATGGCGCTCAAGAACAAATACAGAAAGCAACTTTGCCCACCATACGCGCCCTGGCGAACGCACCAGCCAGTTCTCCTCTATCAGAAATCGACCAAGAAGCCGTCGTCAGATTCATTGTGTCGCTAACCAAAACTAATTACGAATTGGAAGACAGCCAGGCGGGCATGGCGACGGTGCTGTGTCAGTACCTGGTGCGGCGGAGCGGGGCGCCGGAGTCGGGGCTGGCGTGCCGCGTGCTCGCACTACTGGCGCCACCGCGGGACGTACGCCGCGCCAGCGAGCTCGCCGCCACGCTCAGAGACCTCTGCGTGAAATTACCCGATAAACAATCGTGTCGAAACTTAACACGTTACTTGGGCGCTTTGGAAGCTACCGAACGAGCCAGTCTCCACAAAATTTCGAGCATAGCGGAAGGAACGTTACAGGATGACACGATGGTGATGGGTCGCGCCACCACGTCGTTACCACAACCGATAGCGCGCAGTACGCACGTGGTCGTCAACGAAACCGTCGAGGAAGAAGACGAAATCGATGAGACGTCTCCAACTGAAATCTTCTGTAAGATACCAGAAGAAAAATCACAAACCGAAGAGAGTAATACAAAGTCTAGTAGACAGTCTACCGAATCAGAATCTGTTCCAATACGAGATACCAAAGATATATTGTCGGATTCTAGCAGCGGAGTATCTCCGGTGAAGAAAGCTAAAATATCAAAAGTACCAAAAAAGAAGATGCCGGCGAAGAAATCGTCTACCATTGAAACGGCCAATAAAGCGAAAGTCACAGAAACCACTAAAAAGTCGAAACAGAAAACTGAAGAAACTGAAAAGGGTGTCAAACGAAGTCGATCGCAGCGATCCCTGGTGGACGTCGATAGAGTTTCATCCAAAGCTCAAAAAAACAAAGAGTCTAAAACAAAGATGGCCTCTCCGCCGCCGAGCGTGCCCGCTGAGCTGGACGTGTCGAACGTGACTGTGCGGCGCTCCGCCCGCGCCGCGCACTCCTCCTCCAGCCGCGAGTCGACCGTATCGAATGGGACTCAACGAAAAAATAAAAAAGGAGAAGTCAGAACAGGAACACGTTCGTCGGGGCGCAGTAGTACGGCGAGCAGCTCGCGTGACTCTCTCCAAGACTCGTTCGACGATACCACACTCCACACTATTGTTTACGACAAGGAAATGGAACAAGAAATATTGGACGATTCTAGTGAACTAATGGAGAGTAAACGAGCGTCAAAAGGAAATGTCACAATACCTGAAACACCGGAGGCGAGCGATGAATCTGAACCCGAACCAGAGACAATAAAACCGAAAGGGAAAAGAAACACAAAAAAGAAATAG

Protein

MAPTDAEIPTTVLSSRPNPRNNPIMFKIFQNVQFNVVQHKKYVKEMSKLYRKLDEESFRESFKNALMYLFTFGDTSANVDRVIQFVATFCTSLNDEEEFLLFIFEVIFDCQCVSGQSVRYRASQLLAAVLAALGEDASLDDDLCDKLLASQMQRLQDTRGAVRCRAALALQRLQNPMEPDDEVTRAYRFHMSCDPSSSVRRAVVMSIAKCTRNVPFVLERLCDVDEAVRRAAFLYIAALNVTQLRVRQRVLTLKVGLTERSVRVRRVVEEILIPSWLSSFQGNIIHLLKAIRLDNAHDAKDSQYVAGKLLESLFKRLPISELLEWLPTEKNLRLIPADKLNKETAWYWRHLTEHLQKIDDDETLETILPDLVVLTGYIRAIVESPCPSESEDPVGFSTRQYVLHELGSLLRAYDATDPAGRVALQALVTDVLTGDYGPLCSDVIRALVAALELVVPEVSPRMEVISGVISALRDPPETEAPPIIPPPAVDTNEMKLQRARLRVSLNVAMEAQEEAVKDQNYSLAAQCKAKVEDIQKKLEELNIQPTPPPPAAPTIREKLSDAATLNKCLTILNSALDTPQLQTVTPMLRMIFNELEVEIFQNPEIIETALETVALFGILDKEFAKENKSFFFANLIDTSNETVVSTVLKCIVDLLCVHGAKVFEDEATELTCDVTDSANASRKRSTYIDAIDDEGNISESAISMSPNHSTVIELLLKIMDSACAAYRLIIVEGMCRLLHLGHLESPAILSRLLLLWFNPATVDEDMLRQTIGVFFQTFPMCVDGAQEQIQKATLPTIRALANAPASSPLSEIDQEAVVRFIVSLTKTNYELEDSQAGMATVLCQYLVRRSGAPESGLACRVLALLAPPRDVRRASELAATLRDLCVKLPDKQSCRNLTRYLGALEATERASLHKISSIAEGTLQDDTMVMGRATTSLPQPIARSTHVVVNETVEEEDEIDETSPTEIFCKIPEEKSQTEESNTKSSRQSTESESVPIRDTKDILSDSSSGVSPVKKAKISKVPKKKMPAKKSSTIETANKAKVTETTKKSKQKTEETEKGVKRSRSQRSLVDVDRVSSKAQKNKESKTKMASPPPSVPAELDVSNVTVRRSARAAHSSSSRESTVSNGTQRKNKKGEVRTGTRSSGRSSTASSSRDSLQDSFDDTTLHTIVYDKEMEQEILDDSSELMESKRASKGNVTIPETPEASDESEPEPETIKPKGKRNTKKK

Description

Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerase.

Subunit

Component of the condensin complex, which contains the XCAP-E/SMC2 and XCAP-C/SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: XCAP-H/NCAPH, XCAP-D2/NCAPD2 and XCAP-G/NCAPG.

Similarity

Belongs to the CND3 (condensin subunit 3) family.

Keywords

Cell cycle   Cell division   Chromosome   Cytoplasm   DNA condensation   Mitosis   Nucleus   Phosphoprotein   Repeat  

Feature

chain  Condensin complex subunit 3

Uniprot

H9JTW2   A0A437BAL8   A0A2A4K2L5   A0A194Q010   A0A212FMN1   A0A195C9T2   + More
A0A158NIT3   A0A026W868   E9IZS6   A0A151WUK5   A0A087ZT91   A0A195ECZ6   A0A195C689   F4WDC7   A0A151JW41   E2AIZ3   A0A0L7QM91   A0A154P3U5   A0A182NH86   A0A182P3R0   A0A2B4SAV4   Q16R75   A0A1S4FSD1   A0A182JQ35   I3MUQ8   A0A3B5KTF6   A0A3Q1J1C9   I3JR79   A0A147A7I0   A0A3Q2P4K4   M4A5V7   A0A3M6T7D1   I3JR78   H3BDF7   A0A3P9ITA8   A0A3P9ITC6   A0A3P9LTW0   A0A3B3I570   A0A3P9LTX6   B0WJL7   A0A2K5HQQ0   H2LMK8   A0A1L8HTE1   A0A3Q3N074   A0A2D0QE29   A0A2K5HQR5   A0A3B3W145   A0A315W5I8   H3CGA7   Q6NUF0   A0A096LYK9   A0A1S3EJQ6   A0A3Q2DDJ9   A0A1S3EMB6   A0A3B3Y7X2   M3XGW8   A0A2K6KY62   A0A2K6P9B2   A0A3P9NRM9   A0A1W4WE27   Q9YHB5   A0A087XRY0   A1A5J9   A0A1Q3EW93   A0A084VEZ5   Q6P4X7   A0A3B5A173   F7E530  

Pubmed

19121390    26354079    22118469    21347285    24508170    30249741    + More
21282665    21719571    20798317    17510324    25186727    23542700    30382153    9215903    17554307    27762356    29703783    15496914    25362486    9160743    9774278    10428035    24438588    20431018   

EMBL

BABH01003677    BABH01003678    RSAL01000102    RVE47450.1    NWSH01000252    PCG78013.1    + More
KQ459582    KPI98917.1    AGBW02007651    OWR54950.1    KQ978068    KYM97619.1    ADTU01017130    KK107405    QOIP01000014    EZA51214.1    RLU14942.1    GL767232    EFZ14006.1    KQ982730    KYQ51533.1    KQ979074    KYN22692.1    KQ978220    KYM96379.1    GL888087    EGI67707.1    KQ981667    KYN38455.1    GL439921    EFN66582.1    KQ414894    KOC59737.1    KQ434809    KZC06492.1    LSMT01000144    PFX25708.1    CH477722    EAT36904.1    AGTP01011454    AERX01027870    GCES01012111    JAR74212.1    RCHS01004180    RMX37214.1    AFYH01025201    AFYH01025202    AFYH01025203    AFYH01025204    AFYH01025205    AFYH01025206    AFYH01025207    AFYH01025208    AFYH01025209    AFYH01025210    DS231961    EDS29244.1    CM004466    OCT99386.1    NHOQ01000347    PWA30588.1    BC068641    AAH68641.1    AYCK01004603    AF111423    BC041184    BC128686    AAI28687.1    GFDL01015466    JAV19579.1    ATLV01012358    KE524785    KFB36539.1    BC063208    BC076656    AAH63208.1    AAH76656.1    AAMC01108936    AAMC01108937   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053268    UP000007151    UP000078542    + More
UP000005205    UP000053097    UP000279307    UP000075809    UP000005203    UP000078492    UP000007755    UP000078541    UP000000311    UP000053825    UP000076502    UP000075884    UP000075885    UP000225706    UP000008820    UP000075881    UP000005215    UP000261380    UP000265040    UP000005207    UP000265000    UP000002852    UP000275408    UP000008672    UP000265200    UP000265180    UP000001038    UP000002320    UP000233080    UP000186698    UP000261640    UP000221080    UP000261500    UP000007303    UP000028760    UP000081671    UP000265020    UP000261480    UP000233180    UP000233200    UP000242638    UP000192223    UP000030765    UP000261400    UP000008143   

PRIDE

H9JTW2    Q9YHB5   

Pfam

PF12719   Cnd3        + More
PF02151   UVR

Interpro

IPR027165   CND3        + More
IPR025977   Cnd3_C       
IPR016024   ARM-type_fold       
IPR011989   ARM-like       
IPR001943   UVR_dom       

SUPFAM

SSF48371   SSF48371       

Gene 3D

1.25.10.10    

ProteinModelPortal

H9JTW2   A0A437BAL8   A0A2A4K2L5   A0A194Q010   A0A212FMN1   A0A195C9T2   + More
A0A158NIT3   A0A026W868   E9IZS6   A0A151WUK5   A0A087ZT91   A0A195ECZ6   A0A195C689   F4WDC7   A0A151JW41   E2AIZ3   A0A0L7QM91   A0A154P3U5   A0A182NH86   A0A182P3R0   A0A2B4SAV4   Q16R75   A0A1S4FSD1   A0A182JQ35   I3MUQ8   A0A3B5KTF6   A0A3Q1J1C9   I3JR79   A0A147A7I0   A0A3Q2P4K4   M4A5V7   A0A3M6T7D1   I3JR78   H3BDF7   A0A3P9ITA8   A0A3P9ITC6   A0A3P9LTW0   A0A3B3I570   A0A3P9LTX6   B0WJL7   A0A2K5HQQ0   H2LMK8   A0A1L8HTE1   A0A3Q3N074   A0A2D0QE29   A0A2K5HQR5   A0A3B3W145   A0A315W5I8   H3CGA7   Q6NUF0   A0A096LYK9   A0A1S3EJQ6   A0A3Q2DDJ9   A0A1S3EMB6   A0A3B3Y7X2   M3XGW8   A0A2K6KY62   A0A2K6P9B2   A0A3P9NRM9   A0A1W4WE27   Q9YHB5   A0A087XRY0   A1A5J9   A0A1Q3EW93   A0A084VEZ5   Q6P4X7   A0A3B5A173   F7E530  

PDB

6IGX     E-value=1.88208e-39,     Score=413

KEGG

101736052    K06678 condensin complex subunit 3 | (RefSeq) condensin complex subunit 3

GO

GO:0000796   GO:0007076   GO:0000779   GO:0005737   GO:0000793   GO:0051301   GO:0005829   GO:0005634   GO:0005488   GO:0016614   GO:0050660   GO:0006413   GO:0031369   GO:0003723   GO:0006730   GO:0009258   GO:0016155   GO:0003824  

PANTHER

PTHR14418  

Subcellular location

Nucleus   In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase (By similarity).   With evidence from 1 publications.
Cytoplasm   In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase (By similarity).   With evidence from 1 publications.
Chromosome   In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase (By similarity).   With evidence from 1 publications.

Length:

1228

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00478999999999998

Exp number, first 60 AAs:

1e-05

Total prob of N-in:

0.00023

outside

1  -  1228

 

 

Pi

212.252694

Theta

172.687221

Tajima's D

0.789255

CLR

0.878316

CSRT

0.60021998900055

Interpretation

Uncertain