Gene

KWMTBOMO09646

Pre Gene Modal

BGIBMGA012863

Annotation

PREDICTED:_glucose_dehydrogenase_[FAD?_quinone]-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr16(+):6105028-6112847      View in EpiBrowser

Full name

Glucose dehydrogenase [FAD, quinone]      

Location in the cell

Cytoplasmic   Reliability : 1.323 Mitochondrial   Reliability : 1.08

CDS

ATGAGAGGTCACGCTGCCGATTACGACGGATGGGCGGTAAACGGCGCCGAGGGTTGGTCGTGGTTCGATGTACTTCCACACTTCTTAAAAAGCGAAGACAATAAGGAAATCGGGAGCGGGGTGTCTAGTCAATATCATACAACTGGTGGCCTCATGCCGGTGCAAAAGTTCCGGTATGCGCCGCAGTTCGCTCATGATGTGGTCTCAGCTGCAATTGAGCTCGGATATCCTCCTACTAGTGATCTGAATGGGGAAACGATAACAGGATTCACAATCGCACAAGCTATGAATGATGGAGGTTCACGCTATAGTTCGGCTCGTGCATTCCTCCGTCCTGCGGCACACAGGGAGAATCTACACGTTTTACTTAACGCCATGGGTTCAAGGGTCATCATTGATCCACTTGAAAAGAAAGTCACTGCTGTTGAGTACATAAAAAATGGTGAAACGAAAACAGTCGAAGTTATAAAAGAGGCAATACTATCAGCAGGGACATTGAACTCTCCGCAAATATTACTTCTATCTGGAGTGGGGCCAAGAGAGACTCTTGATAAATTTAATATACCAACTATACAAGAGCTCCCAGGTGTAGGACAAAACTTACAAAATCATGTCGGAGTTCAGCTCTCCTTCAGATTGACAAAGGAGCCCGATGTGCCTGTGTTGAATTGGGCAACCGCTATGGAGTATATGCTCAACAGAATGGGTCCTATGTCAGGAACTGGAATGTCTCAATTAACAGGTATTGTTAACTCTCGGTACGCGCCTTCGGGCGGACGTCATCCTGACATACAATTCTTCTTTGGCGGCTATTATGCCACCTGTGGAGACGGTGTAGTACCTGATGACGTGAAAGTGAAAGAAATTACAGATAAGAAGGAGATATCGATATCAGCGATATCTCTACATCCACGCAGTCGCGGCTACCTAACTTTGCAGTCCGTTGATCCAACGCAGCCGCCGCTCATGCAACCGAACTACTTTTATGACGAGCACGAGCTGGATGTGCTAGTTGAGGCCGCTCAAATCGCTTATAAACTAGCTAACACTACGATAATGCGTGAAAAGTATGGAATGACTCCAACAGAAGGATATGGGAGTGAATGTGAGGGCGGTGGACTTTCTCCGACACCTGAATTCTTTAGGTGTTTGGCGCAACATCAAACCGCCCCTGAAAACCACCAAGTTGGTACTTGCAAGATGGGGCCGCGTACCGACCCGATGGCTGTAGTGGATATGCAGCTTAGGGTTCATGGAATAAAGGGTTTACGCGTGGCTGATGCGTCAATCATGCCAACGGTTCCGTCAGGTAATACGGCGGCACCTACCATAATGATAGCGGAAAGAGCAGCAGAATTTGTTACAACTAGATACCAACAAGCGAAGAGAACGCCAGCGGAACTAGGGAATCGTTTCGGTCACCCCAGCGACTCCAGCGCCAATAATGAGAACAGGTACTGTAGCCAAATAGAAGAAATATAG

Protein

MRGHAADYDGWAVNGAEGWSWFDVLPHFLKSEDNKEIGSGVSSQYHTTGGLMPVQKFRYAPQFAHDVVSAAIELGYPPTSDLNGETITGFTIAQAMNDGGSRYSSARAFLRPAAHRENLHVLLNAMGSRVIIDPLEKKVTAVEYIKNGETKTVEVIKEAILSAGTLNSPQILLLSGVGPRETLDKFNIPTIQELPGVGQNLQNHVGVQLSFRLTKEPDVPVLNWATAMEYMLNRMGPMSGTGMSQLTGIVNSRYAPSGGRHPDIQFFFGGYYATCGDGVVPDDVKVKEITDKKEISISAISLHPRSRGYLTLQSVDPTQPPLMQPNYFYDEHELDVLVEAAQIAYKLANTTIMREKYGMTPTEGYGSECEGGGLSPTPEFFRCLAQHQTAPENHQVGTCKMGPRTDPMAVVDMQLRVHGIKGLRVADASIMPTVPSGNTAAPTIMIAERAAEFVTTRYQQAKRTPAELGNRFGHPSDSSANNENRYCSQIEEI

Catalytic Activity

a quinone + D-glucose = a quinol + D-glucono-1,5-lactone

Cofactor

FAD

Similarity

Belongs to the GMC oxidoreductase family.

Keywords

Complete proteome   FAD   Flavoprotein   Oxidoreductase   Reference proteome   Secreted   Selenocysteine   Signal  

Feature

chain  Glucose dehydrogenase [FAD, quinone]

Uniprot

H9JTK1   A0A3S2LZ99   A0A2H1VAE8   A0A2A4K284   A0A194Q0T0   A0A194RR25   + More
A0A212FMI8   D6WPB8   A0A2P8XMK6   A0A1Y1KHY8   A0A2J7QLL4   D6WN48   A0A067QZE3   A0A1W4WY11   A0A0L7R727   A0A026WYN9   V5GRM6   A0A310S8C1   W5JT22   A0A3L8D997   K7J6M6   E2BSK4   A0A151I4A5   A0A2M4CT25   Q6WMW1   A0A182FNW9   A0A1Q3FMN1   A0A1A9Z6K6   A0A1B0FAV7   A0A154P559   A0A1Y1MP57   J9JWH7   B3P2V7   E2AC28   A0A1L2FPC1   A0A1A9Y074   B0XCE5   A0A1Q3FML5   A0A182J274   A0A182VBZ4   A0A182XAV1   A0A182LES2   Q7QCC5   A0A182HSP9   A0A158NI12   A0A0M4ECE1   A0A1A9VQK6   A0A182MWU5   A0A182UL69   B0WR76   A0A1A9WL86   A0A195CKP9   Q6WMW0   A0A088A030   K7ITZ6   A0A1B6MKL9   B4K6N7   Q6WMV8   A0A182NRL5   B4M4G1   A0A182R0I2   A0A182VWW9   Q6WMV7   Q6WMW3   A0A151WJR8   A0A1L2FPB1   A0A1L2FPB2   A0A0R1E1G4   N6T584   A0A182RS69   Q6WMV9   A0A1B6HHA9   Q56RK5   Q56RL4   Q6WMW2   A0A0M9A7L5   A0A195F7M9   A0A0L0CK46   U3PT72   A0A2U8U0K3   P18173   A0A1J1IAM9   B4PRY5   B4I4R7   F4WPR1   Q8SXV0   B4JFA8   A0A023EV68   A0A232F9V9   B4GMR4   D0QWK8   A0A2H8TVD6   A0A2R7WDP0   A0A182G8A0   A0A3B0JPT6   A0A2S2NJV8   B3LYF6   A0A232EXY1   A0A3Q0J5T3   A0A0C9S068  

EC Number

1.1.5.9

Pubmed

19121390    26354079    22118469    18362917    19820115    29403074    + More
28004739    24845553    24508170    20920257    23761445    30249741    20075255    20798317    14738315    17994087    20966253    12364791    14747013    17210077    21347285    17550304    23537049    15545653    16547107    26108605    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    2108306    3143620    2002763    21719571    24945155    28648823    19859648    26483478   

EMBL

BABH01003678    BABH01003679    RSAL01000102    RVE47449.1    ODYU01001490    SOQ37766.1    + More
NWSH01000252    PCG78014.1    KQ459582    KPI98918.1    KQ459700    KPJ20333.1    AGBW02007651    OWR54951.1    KQ971354    EFA07378.1    PYGN01001713    PSN33241.1    GEZM01085307    JAV60011.1    NEVH01013243    PNF29476.1    KQ971342    EFA03070.1    KK853157    KDR10473.1    KQ414643    KOC66687.1    KK107078    EZA60259.1    GALX01004184    JAB64282.1    KQ764717    OAD54441.1    ADMH02000453    ETN66423.1    QOIP01000011    RLU16896.1    AAZX01006009    AAZX01015631    GL450240    EFN81337.1    KQ976456    KYM84861.1    GGFL01004328    MBW68506.1    AY279331    AAQ17521.1    GFDL01006263    JAV28782.1    CCAG010022189    KQ434809    KZC06464.1    GEZM01025416    JAV87459.1    ABLF02025721    CH954181    EDV48129.1    GL438389    EFN69046.1    KX398862    ANZ79231.1    DS232687    EDS44775.1    GFDL01006281    JAV28764.1    AAAB01008859    EAA08043.3    APCN01000318    ADTU01016167    ADTU01016168    ADTU01016169    CP012526    ALC45304.1    AXCM01004736    DS232052    EDS33250.1    KQ977622    KYN01283.1    AY279332    AAQ17522.1    GEBQ01003534    JAT36443.1    CH933806    EDW14153.2    AY279334    AAQ17524.1    CH940652    EDW59522.2    AXCN02000004    AY279335    AAQ17525.1    AY279329    AAQ17519.1    KQ983039    KYQ48074.1    KX398860    ANZ79229.1    KX398861    ANZ79230.1    CM000160    KRK03116.1    APGK01052299    APGK01052300    APGK01052301    KB741211    ENN72828.1    AY279333    AAQ17523.1    GECU01033735    JAS73971.1    AY754502    AAX13077.1    AY754493    AAX13068.1    AY279330    AAQ17520.1    KQ435719    KOX78880.1    KQ981763    KYN36069.1    JRES01000297    KNC32631.1    BT150358    AGW52167.1    AE014297    AWM95310.1    M29298    X13582    CVRI01000047    CRK97304.1    EDW96385.1    CH480821    EDW55210.1    GL888255    EGI63752.1    AY084122    AAL89860.1    CH916369    EDV93389.1    GAPW01000590    JAC13008.1    NNAY01000667    OXU27097.1    CH479185    EDW38138.1    FJ821032    ACN94707.1    GFXV01006409    MBW18214.1    KK854669    PTY17762.1    JXUM01047839    JXUM01047840    JXUM01047841    KQ561535    KXJ78234.1    OUUW01000008    SPP84125.1    GGMR01004840    MBY17459.1    CH902617    EDV41819.2    NNAY01001705    OXU23175.1    GBYB01013861    JAG83628.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053268    UP000053240    UP000007151    + More
UP000007266    UP000245037    UP000235965    UP000027135    UP000192223    UP000053825    UP000053097    UP000000673    UP000279307    UP000002358    UP000008237    UP000078540    UP000069272    UP000092445    UP000092444    UP000076502    UP000007819    UP000008711    UP000000311    UP000092443    UP000002320    UP000075880    UP000075903    UP000076407    UP000075882    UP000007062    UP000075840    UP000005205    UP000092553    UP000078200    UP000075883    UP000075902    UP000091820    UP000078542    UP000005203    UP000009192    UP000075884    UP000008792    UP000075886    UP000075920    UP000075809    UP000002282    UP000019118    UP000075900    UP000053105    UP000078541    UP000037069    UP000000803    UP000183832    UP000001292    UP000007755    UP000001070    UP000215335    UP000008744    UP000069940    UP000249989    UP000268350    UP000007801    UP000079169   

PRIDE

H9JTK1    U3PT72    P18173    Q8SXV0   

Pfam

PF05199   GMC_oxred_C        + More
PF00732   GMC_oxred_N

Interpro

IPR036188   FAD/NAD-bd_sf        + More
IPR027424   Glucose_Oxidase_domain_2       
IPR000172   GMC_OxRdtase_N       
IPR007867   GMC_OxRtase_C       
IPR012132   GMC_OxRdtase       

SUPFAM

SSF51905   SSF51905       

Gene 3D

3.50.50.60     4.10.450.10    

ProteinModelPortal

H9JTK1   A0A3S2LZ99   A0A2H1VAE8   A0A2A4K284   A0A194Q0T0   A0A194RR25   + More
A0A212FMI8   D6WPB8   A0A2P8XMK6   A0A1Y1KHY8   A0A2J7QLL4   D6WN48   A0A067QZE3   A0A1W4WY11   A0A0L7R727   A0A026WYN9   V5GRM6   A0A310S8C1   W5JT22   A0A3L8D997   K7J6M6   E2BSK4   A0A151I4A5   A0A2M4CT25   Q6WMW1   A0A182FNW9   A0A1Q3FMN1   A0A1A9Z6K6   A0A1B0FAV7   A0A154P559   A0A1Y1MP57   J9JWH7   B3P2V7   E2AC28   A0A1L2FPC1   A0A1A9Y074   B0XCE5   A0A1Q3FML5   A0A182J274   A0A182VBZ4   A0A182XAV1   A0A182LES2   Q7QCC5   A0A182HSP9   A0A158NI12   A0A0M4ECE1   A0A1A9VQK6   A0A182MWU5   A0A182UL69   B0WR76   A0A1A9WL86   A0A195CKP9   Q6WMW0   A0A088A030   K7ITZ6   A0A1B6MKL9   B4K6N7   Q6WMV8   A0A182NRL5   B4M4G1   A0A182R0I2   A0A182VWW9   Q6WMV7   Q6WMW3   A0A151WJR8   A0A1L2FPB1   A0A1L2FPB2   A0A0R1E1G4   N6T584   A0A182RS69   Q6WMV9   A0A1B6HHA9   Q56RK5   Q56RL4   Q6WMW2   A0A0M9A7L5   A0A195F7M9   A0A0L0CK46   U3PT72   A0A2U8U0K3   P18173   A0A1J1IAM9   B4PRY5   B4I4R7   F4WPR1   Q8SXV0   B4JFA8   A0A023EV68   A0A232F9V9   B4GMR4   D0QWK8   A0A2H8TVD6   A0A2R7WDP0   A0A182G8A0   A0A3B0JPT6   A0A2S2NJV8   B3LYF6   A0A232EXY1   A0A3Q0J5T3   A0A0C9S068  

PDB

5NCC     E-value=1.10985e-52,     Score=523

KEGG

101739464    K00115 glucose 1-dehydrogenase (FAD, quinone) [EC:1.1.5.9] | (RefSeq) glucose dehydrogenase [FAD, qu

PATHWAY

00030    Pentose phosphate pathway - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016614   GO:0050660   GO:0006006   GO:0008364   GO:0046693   GO:0005576   GO:0016021   GO:0016491   GO:0006413   GO:0031369   GO:0003723   GO:0006730   GO:0009258   GO:0016155   GO:0003824   GO:0055114  

Subcellular location

Secreted  

Length:

493

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0108

Exp number, first 60 AAs:

0.00059

Total prob of N-in:

0.00420

outside

1  -  493

 

 

Pi

255.09547

Theta

173.565156

Tajima's D

1.161908

CLR

0.093509

CSRT

0.709764511774411

Interpretation

Uncertain