Gene
KWMTBOMO09621 Validated by peptides from experiments
Pre Gene Modal
BGIBMGA012851
Annotation
PREDICTED:_eukaryotic_translation_initiation_factor_3_subunit_C_isoform_X1_[Bombyx_mori]
Full name
Eukaryotic translation initiation factor 3 subunit C
Alternative Name
Eukaryotic translation initiation factor 3 subunit 8
Location in the cell
Nuclear Reliability : 3.757
Sequence
CDS
ATGAGTCGTTTCTTTGCAACTGGGACGGACTCGGAGTCAGAGAGCAGCAGCGAGGACGAGCCAGTAGTACGCGCCCCCGCGCCAGTTTACACGTTTAGTGACGATGAGGAAGAAACAAAGCGAGTTGTGCGCTCAATGAAAGAGAAGCGTTATGAGGAATTAGAAGGAATTATACACTCTATACGCAATCATCGGAAAATCAAGGATTTTAGTTCAGCATTAGCTTCTTTCGAAGAGCTCCAAAAGGCATACACTCGAGCCGCACCGGTTGTTCAAAAGGAGGAGAATGGAGTTGCTCCTAGATTCTTCATAAGAGCTCTTGTAGAATTGGACGATTGGGTAGTAGGAGCATGGAATGAACGTGAAGCCCGAAAAGCTCTATCAAAAGGAAACAGTAAAGCTCTTACCTCACTAAGACAGAAACTTAGGAAGTACACTAAAGATTTTGAAGCTGAAATATCCAAGTTCCGTGAAGATCCTGATCTACCCGATGACAATGAACGTAAAGATTCATCATCATCAGATGAGTCTGAAGATGAAGAAAAACCAATTAAAGAGAAGCCTAAACCCGAGCCCCTTCTTCGTCCACCACCAGAAGATGATGAATCATCAGATTCTATGGATTGGGCTTCTAGTTCTTCTGACTCCAGTTTTAGCTCTGATGATGAGGAACGTGGTACCTCCAATATTCGTGAACAATTCATCAAGAAAGTTACCAAGAAAGAGGATGATGAAGAGAAAATAAAACTTAAACTAAAGAAACGTGAGGAAAGACGTGAAAGGTCTGGTAAAATCAATAAACGCGACGTAGCTGATGATGGTGGTGAATGGGAAACAGTCAGAAAGGGTGCGGCGACTTCTGATAAGCCTAAAATGTTCGCTAAAGATAGTGATATTGATGCTGCACTTGTCGTGAAGAAACTTGGTGAAATAAGCGCAGCCAGAGGTCGAAAAAGAACTGATCGTCGTGCTCAGTTAGAACTTTTACATGAGTTGCGTACTGTTGCGCTTCAACATAATTTGGGAGATGCACTACAACTAAAACTACGCTCGGCCATCGTGGCTGCCCTCTTTGACTATAATCCTAAAGTCTCTGATGCAATGAAACCGGAATATTGGTCAAAACTGGTTGAAAATATTGATCACATGGTAACTCTTCTTCTGGCTCACGAAGATATGGTTCTGAGTGAGACAATCCTTGAAGAGAATGAACAACTCGTCACACCACCATACCAAGTTCGCGGTTGTCTACTTACTTATCTGGAAAGACTTGATGATGAATTTACCAAGTTGCTAAAAGAATGTGACCCACATTCTAATGAGTATGTAGAGAGATTAAAAGATGAAGTGCGAGTTTCAGCTCTCATTGACCGTGTATGTCAAGTTGTTGAACGTGATGGTACACCTCAAGAAATTTGTAGGGCGTATCTAAGAAAAATAGATCATTTGTACTACAAATTTGATCCACGTGCAGTTCGAAAAGATCTTCCGCCTACTGAGGAAACAACTATTAAGAAAATGGAACGTTACTGCAAATACATTTATGCCCATGATGAGACCGATCGTCTGAGAACTCGTGCTATACTTTCTCATATCTATCACCATGCCCTGCATGACAACTGGTTCCAAGCCCGTGATTTGTTACTCATGTCTCATCTTCAAGAGACCGTACAACACTCTGATCCTAGTACACAGATTTTGTATAATCGGACAATGGCTAATTTAGGTCTGTGTGCTTTTCGCCGAGGTAACGTGAAAGAAGCTCATGGCTGTTTGGCCGAGTTAATGATGACTGGAAAGCCTAAAGAGCTATTGGCTCAAGGTCTACTACCTCAACGTCAACATGAGCGCTCAAAGGAGCAGGAGAAAATTGAAAAACAACGCCAGATGCCTTTTCACATGCACATTAATCTGGAATTACTCGAGTGTGTCTATTTAGTATCAGCGATGCTGATTGAGATTCCGTACATGGCAGCACACGAATTTGATGCCCGACGTCGCATGATTAGTAAAACTTTCTATCAAAATCTACGTGCTAGTGAACGTCAGGCGCTTGTCGGCCCTCCTGAGTCGATGCGAGAGCACGCAGTGGCGGCTGCAAGGGCCATGCGCAGAGGTGATTGGAGAGCTTGCCTAAATTACATCGTGAATGAAAAAATGAATGCCAAGGTTTGGGATTTAATGGTCGGAGCTGATAATGTTCGTGCAATGCTAGGTCGTCTTATACGTGAAGAGTCCCTACGTACCTATCTGTTCACATATGCTCACGTGTACGCGTCACTGTCATTGCGTTCTCTCGCTGACATGTTTGAATTACCACGTCAACGCGTACATTCTCTAGTGTCTAAAATGATCATCAACGAGGAGCTCTTGGCATCATTGGATGACCCGAGCGAATGTGCTATCTTGCACCGTTCCGAACCAACACGTATGCAGGCTCTGGCACTACAGCTTGCCGACAAGGTCGGAAATTTGGTGGATTCGAATGAGCGTATATTCGAAAAACAAGGCTCGTTCTTCCAACGGGGCGGCGCACAGCGCGGGGAGGGGCGTCAGCGAGAGCGGCCGCGTGAGGGCTGGAACCGACGCACCCGCAACCGTCGCCGCGACGACGAACGCGCAGACGACTAG
Protein
MSRFFATGTDSESESSSEDEPVVRAPAPVYTFSDDEEETKRVVRSMKEKRYEELEGIIHSIRNHRKIKDFSSALASFEELQKAYTRAAPVVQKEENGVAPRFFIRALVELDDWVVGAWNEREARKALSKGNSKALTSLRQKLRKYTKDFEAEISKFREDPDLPDDNERKDSSSSDESEDEEKPIKEKPKPEPLLRPPPEDDESSDSMDWASSSSDSSFSSDDEERGTSNIREQFIKKVTKKEDDEEKIKLKLKKREERRERSGKINKRDVADDGGEWETVRKGAATSDKPKMFAKDSDIDAALVVKKLGEISAARGRKRTDRRAQLELLHELRTVALQHNLGDALQLKLRSAIVAALFDYNPKVSDAMKPEYWSKLVENIDHMVTLLLAHEDMVLSETILEENEQLVTPPYQVRGCLLTYLERLDDEFTKLLKECDPHSNEYVERLKDEVRVSALIDRVCQVVERDGTPQEICRAYLRKIDHLYYKFDPRAVRKDLPPTEETTIKKMERYCKYIYAHDETDRLRTRAILSHIYHHALHDNWFQARDLLLMSHLQETVQHSDPSTQILYNRTMANLGLCAFRRGNVKEAHGCLAELMMTGKPKELLAQGLLPQRQHERSKEQEKIEKQRQMPFHMHINLELLECVYLVSAMLIEIPYMAAHEFDARRRMISKTFYQNLRASERQALVGPPESMREHAVAAARAMRRGDWRACLNYIVNEKMNAKVWDLMVGADNVRAMLGRLIREESLRTYLFTYAHVYASLSLRSLADMFELPRQRVHSLVSKMIINEELLASLDDPSECAILHRSEPTRMQALALQLADKVGNLVDSNERIFEKQGSFFQRGGAQRGEGRQRERPREGWNRRTRNRRRDDERADD
Summary
Description
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
Subunit
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
Similarity
Belongs to the eIF-3 subunit C family.
Keywords
Complete proteome
Cytoplasm
Initiation factor
Protein biosynthesis
Reference proteome
Feature
chain Eukaryotic translation initiation factor 3 subunit C
Uniprot
Pubmed
EMBL
Proteomes
SUPFAM
SSF46785
SSF46785
ProteinModelPortal
PDB
6FEC
E-value=0,
Score=1690
Ontologies
GO
PANTHER
Topology
Subcellular location
Cytoplasm
Length:
876
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.46275
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00040
outside
1 - 876
Population Genetic Test Statistics
Pi
185.535749
Theta
212.527434
Tajima's D
-0.471304
CLR
165.681713
CSRT
0.242437878106095
Interpretation
Possibly Positive selection
