Gene
KWMTBOMO09618
Annotation
PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_31_isoform_X2_[Amyelois_transitella]
Full name
Mediator of RNA polymerase II transcription subunit 31
Alternative Name
Mediator complex subunit 31
Location in the cell
Nuclear Reliability : 1.932
Sequence
CDS
ATGATGGCTGGAAAAGTAATGCCAGAAACTGAAGAGCAGAATCGAATAAGATTTCAAGTGGAACTTGAATTTGTGCAGTGCTTAGCAAATCCAAATTACATTCACTTTTTGGCACAGCGAGGTTATCTTAAAGAACAAACTTTTGTAAACTATCTTAAATATTTGCAATATTGGAGAGAGCCAGAATATGCTAGATATTTGAAGTATCCCATGTGTTTGCATTTTTTGGAGTTATTACAACATGAAGCATTTAGAAGAGAATGTGTATCGGCACAAGTTTGCAAATTCATGGACGATCAAGCAATATTGCTATGGCAACATTATACTCGTCGGCGTACACGCACGTTACAACCGCCGGACGCACCGGCGCTTCCTGCGCCGCCCGCACCGCCACAACAAGGTCCACCAAGACAACAAACTTAG
Protein
MMAGKVMPETEEQNRIRFQVELEFVQCLANPNYIHFLAQRGYLKEQTFVNYLKYLQYWREPEYARYLKYPMCLHFLELLQHEAFRRECVSAQVCKFMDDQAILLWQHYTRRRTRTLQPPDAPALPAPPAPPQQGPPRQQT
Summary
Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Subunit
Component of the Mediator complex.
Similarity
Belongs to the Mediator complex subunit 31 family.
Keywords
Activator
Alternative splicing
Complete proteome
Nucleus
Reference proteome
Transcription
Transcription regulation
Feature
chain Mediator of RNA polymerase II transcription subunit 31
splice variant In isoform 2.
splice variant In isoform 2.
Uniprot
A0A2A4K1J5
A0A2H1V4J9
I4DKI6
A0A3S2NL12
S4Q021
A0A212FMR4
+ More
A0A1B0CVF5 A0A1L8DG01 R4V4H2 A0A067R2N1 E0W3R8 A0A1W4WTW7 A0A182TGH7 A0A1Y1N426 A0A182NMN0 A0A3F2YX47 A0A182VQ18 A0A1S3CYS7 A0A182Y4R2 U5EIU3 A0A182IT71 A0A232ENI8 A0A182X3A6 A0A182F6R4 A0A182VCJ9 K7J4J2 A0A182HZF3 A0A1Q3FW40 A0A0C9R5N5 A0A336M6C3 A0A2M4BXI3 A0A2S2NFA3 A0A2M4AV17 C4WXW4 A0A1I8NTE7 F4WCS5 A0A151WML8 A0A2A3EI20 A0A195EE02 A0A151JWI3 A0A2M3ZCC0 A0A2M4BYH5 A0A1W4WHQ9 A0A2M4BX15 A0A139WGS2 A0A151I2T6 A0A158NIC5 A0A310S805 A0A026WDD4 A0A088AC21 A0A1I8N4L9 A0A0L7R9K7 A0A154PIM6 A0A1W4WTL0 A0A2M4CI09 A0A151IIH0 A0A0L0CI66 T1IXD2 B1GSA1 A0A1B0BT66 A0A1B0FQN0 A0A1W4WHS0 E2A8R4 A0A2M4ASS2 Q7QKB9 A0A1B6HUT6 A0A1A9WJD9 A0A1B6EQ58 E9IPQ7 E2BL77 A0A1I8NTE9 T1DPI8 A0A182PS61 A0A0K8TUW3 W5J624 A0A034WQB7 N6TTY7 A0A1I8N4M2 A0A1S4EAB3 J3JTM8 W8C5Q0 Q17DI7 B4N9B9 A0A182RH55 B3M0F4 A0A0A1XP63 A0A0R3NNA3 A0A2L2YE65 B4GEU0 B5DVG1 E9GJ15 A0A0K8TVV3 A0A3R7QCY2 F5HIT0 Q17DI7-2 A0A1W4UPK4 A0A164WG31 A0A0N7ZX73 A0A023EJZ4 A0A182GI56
A0A1B0CVF5 A0A1L8DG01 R4V4H2 A0A067R2N1 E0W3R8 A0A1W4WTW7 A0A182TGH7 A0A1Y1N426 A0A182NMN0 A0A3F2YX47 A0A182VQ18 A0A1S3CYS7 A0A182Y4R2 U5EIU3 A0A182IT71 A0A232ENI8 A0A182X3A6 A0A182F6R4 A0A182VCJ9 K7J4J2 A0A182HZF3 A0A1Q3FW40 A0A0C9R5N5 A0A336M6C3 A0A2M4BXI3 A0A2S2NFA3 A0A2M4AV17 C4WXW4 A0A1I8NTE7 F4WCS5 A0A151WML8 A0A2A3EI20 A0A195EE02 A0A151JWI3 A0A2M3ZCC0 A0A2M4BYH5 A0A1W4WHQ9 A0A2M4BX15 A0A139WGS2 A0A151I2T6 A0A158NIC5 A0A310S805 A0A026WDD4 A0A088AC21 A0A1I8N4L9 A0A0L7R9K7 A0A154PIM6 A0A1W4WTL0 A0A2M4CI09 A0A151IIH0 A0A0L0CI66 T1IXD2 B1GSA1 A0A1B0BT66 A0A1B0FQN0 A0A1W4WHS0 E2A8R4 A0A2M4ASS2 Q7QKB9 A0A1B6HUT6 A0A1A9WJD9 A0A1B6EQ58 E9IPQ7 E2BL77 A0A1I8NTE9 T1DPI8 A0A182PS61 A0A0K8TUW3 W5J624 A0A034WQB7 N6TTY7 A0A1I8N4M2 A0A1S4EAB3 J3JTM8 W8C5Q0 Q17DI7 B4N9B9 A0A182RH55 B3M0F4 A0A0A1XP63 A0A0R3NNA3 A0A2L2YE65 B4GEU0 B5DVG1 E9GJ15 A0A0K8TVV3 A0A3R7QCY2 F5HIT0 Q17DI7-2 A0A1W4UPK4 A0A164WG31 A0A0N7ZX73 A0A023EJZ4 A0A182GI56
Pubmed
22651552
26354079
23622113
22118469
24845553
20566863
+ More
28004739 25244985 28648823 20075255 21719571 18362917 19820115 21347285 24508170 30249741 25315136 26108605 18348209 20798317 12364791 14747013 17210077 21282665 20920257 23761445 25348373 23537049 22516182 24495485 17510324 17994087 18057021 25830018 15632085 26561354 21292972 24945155 26483478
28004739 25244985 28648823 20075255 21719571 18362917 19820115 21347285 24508170 30249741 25315136 26108605 18348209 20798317 12364791 14747013 17210077 21282665 20920257 23761445 25348373 23537049 22516182 24495485 17510324 17994087 18057021 25830018 15632085 26561354 21292972 24945155 26483478
EMBL
NWSH01000320
PCG77502.1
ODYU01000646
SOQ35775.1
AK401804
LADI01006439
+ More
BAM18426.1 KPJ20639.1 RSAL01000051 RVE50285.1 GAIX01000548 JAA92012.1 AGBW02007651 OWR54980.1 AJWK01030486 GFDF01008708 JAV05376.1 KC740939 AGM32763.1 KK853054 KDR11999.1 DS235882 EEB20274.1 GEZM01014239 JAV92168.1 AXCN02001214 GANO01002492 JAB57379.1 NNAY01003159 OXU19892.1 AAZX01009232 APCN01001973 GFDL01003248 JAV31797.1 GBYB01011614 JAG81381.1 UFQT01000197 SSX21578.1 GGFJ01008646 MBW57787.1 GGMR01003238 MBY15857.1 GGFK01011290 MBW44611.1 ABLF02038090 AK342880 BAH72734.1 GL888071 EGI67994.1 KQ982934 KYQ49142.1 KZ288238 PBC31367.1 KQ979074 KYN23074.1 KQ981643 KYN38681.1 GGFM01005374 MBW26125.1 GGFJ01008647 MBW57788.1 GGFJ01008484 MBW57625.1 KQ971344 KYB27096.1 KQ976525 KYM81976.1 ADTU01016464 KQ774368 OAD52319.1 KK107274 QOIP01000008 EZA53656.1 RLU19764.1 KQ414624 KOC67552.1 KQ434900 KZC11050.1 GGFL01000701 MBW64879.1 KQ977477 KYN02479.1 JRES01000370 KNC31887.1 JH431646 AM492681 CAM34512.1 JXJN01020020 CCAG010023302 GL437663 EFN70143.1 GGFK01010461 MBW43782.1 AAAB01008799 EAA03803.5 GECU01029295 JAS78411.1 GECZ01029711 JAS40058.1 GL764570 EFZ17446.1 GL448949 EFN83563.1 GAMD01001900 JAA99690.1 GDHF01034062 GDHF01027054 GDHF01019471 JAI18252.1 JAI25260.1 JAI32843.1 ADMH02002112 ETN58848.1 GAKP01002562 GAKP01002561 JAC56390.1 APGK01054667 KB741251 KB632404 ENN71851.1 ERL95007.1 BT126585 AEE61549.1 GAMC01004732 GAMC01004731 GAMC01004729 JAC01827.1 CH477293 CH964232 EDW80552.1 CH902617 EDV43160.1 KPU80104.1 GBXI01015921 GBXI01007284 GBXI01001969 JAC98370.1 JAD07008.1 JAD12323.1 CM000070 KRT00701.1 IAAA01026010 LAA06433.1 CH479182 EDW34125.1 EDY68262.1 GL732547 EFX80561.1 GDHF01033901 JAI18413.1 QCYY01003406 ROT63632.1 EGK96191.1 LRGB01001253 KZS13233.1 GDIP01203753 JAJ19649.1 GAPW01004198 JAC09400.1 JXUM01012327 KQ560351 KXJ82896.1
BAM18426.1 KPJ20639.1 RSAL01000051 RVE50285.1 GAIX01000548 JAA92012.1 AGBW02007651 OWR54980.1 AJWK01030486 GFDF01008708 JAV05376.1 KC740939 AGM32763.1 KK853054 KDR11999.1 DS235882 EEB20274.1 GEZM01014239 JAV92168.1 AXCN02001214 GANO01002492 JAB57379.1 NNAY01003159 OXU19892.1 AAZX01009232 APCN01001973 GFDL01003248 JAV31797.1 GBYB01011614 JAG81381.1 UFQT01000197 SSX21578.1 GGFJ01008646 MBW57787.1 GGMR01003238 MBY15857.1 GGFK01011290 MBW44611.1 ABLF02038090 AK342880 BAH72734.1 GL888071 EGI67994.1 KQ982934 KYQ49142.1 KZ288238 PBC31367.1 KQ979074 KYN23074.1 KQ981643 KYN38681.1 GGFM01005374 MBW26125.1 GGFJ01008647 MBW57788.1 GGFJ01008484 MBW57625.1 KQ971344 KYB27096.1 KQ976525 KYM81976.1 ADTU01016464 KQ774368 OAD52319.1 KK107274 QOIP01000008 EZA53656.1 RLU19764.1 KQ414624 KOC67552.1 KQ434900 KZC11050.1 GGFL01000701 MBW64879.1 KQ977477 KYN02479.1 JRES01000370 KNC31887.1 JH431646 AM492681 CAM34512.1 JXJN01020020 CCAG010023302 GL437663 EFN70143.1 GGFK01010461 MBW43782.1 AAAB01008799 EAA03803.5 GECU01029295 JAS78411.1 GECZ01029711 JAS40058.1 GL764570 EFZ17446.1 GL448949 EFN83563.1 GAMD01001900 JAA99690.1 GDHF01034062 GDHF01027054 GDHF01019471 JAI18252.1 JAI25260.1 JAI32843.1 ADMH02002112 ETN58848.1 GAKP01002562 GAKP01002561 JAC56390.1 APGK01054667 KB741251 KB632404 ENN71851.1 ERL95007.1 BT126585 AEE61549.1 GAMC01004732 GAMC01004731 GAMC01004729 JAC01827.1 CH477293 CH964232 EDW80552.1 CH902617 EDV43160.1 KPU80104.1 GBXI01015921 GBXI01007284 GBXI01001969 JAC98370.1 JAD07008.1 JAD12323.1 CM000070 KRT00701.1 IAAA01026010 LAA06433.1 CH479182 EDW34125.1 EDY68262.1 GL732547 EFX80561.1 GDHF01033901 JAI18413.1 QCYY01003406 ROT63632.1 EGK96191.1 LRGB01001253 KZS13233.1 GDIP01203753 JAJ19649.1 GAPW01004198 JAC09400.1 JXUM01012327 KQ560351 KXJ82896.1
Proteomes
UP000218220
UP000053268
UP000283053
UP000007151
UP000092461
UP000027135
+ More
UP000009046 UP000192223 UP000075902 UP000075884 UP000075886 UP000075920 UP000079169 UP000076408 UP000075880 UP000215335 UP000076407 UP000069272 UP000075903 UP000002358 UP000075840 UP000007819 UP000095300 UP000007755 UP000075809 UP000242457 UP000078492 UP000078541 UP000007266 UP000078540 UP000005205 UP000053097 UP000279307 UP000005203 UP000095301 UP000053825 UP000076502 UP000078542 UP000037069 UP000092460 UP000092444 UP000000311 UP000007062 UP000091820 UP000008237 UP000075885 UP000000673 UP000019118 UP000030742 UP000008820 UP000007798 UP000075900 UP000007801 UP000001819 UP000008744 UP000000305 UP000283509 UP000192221 UP000076858 UP000069940 UP000249989
UP000009046 UP000192223 UP000075902 UP000075884 UP000075886 UP000075920 UP000079169 UP000076408 UP000075880 UP000215335 UP000076407 UP000069272 UP000075903 UP000002358 UP000075840 UP000007819 UP000095300 UP000007755 UP000075809 UP000242457 UP000078492 UP000078541 UP000007266 UP000078540 UP000005205 UP000053097 UP000279307 UP000005203 UP000095301 UP000053825 UP000076502 UP000078542 UP000037069 UP000092460 UP000092444 UP000000311 UP000007062 UP000091820 UP000008237 UP000075885 UP000000673 UP000019118 UP000030742 UP000008820 UP000007798 UP000075900 UP000007801 UP000001819 UP000008744 UP000000305 UP000283509 UP000192221 UP000076858 UP000069940 UP000249989
Pfam
PF05669 Med31
Gene 3D
ProteinModelPortal
A0A2A4K1J5
A0A2H1V4J9
I4DKI6
A0A3S2NL12
S4Q021
A0A212FMR4
+ More
A0A1B0CVF5 A0A1L8DG01 R4V4H2 A0A067R2N1 E0W3R8 A0A1W4WTW7 A0A182TGH7 A0A1Y1N426 A0A182NMN0 A0A3F2YX47 A0A182VQ18 A0A1S3CYS7 A0A182Y4R2 U5EIU3 A0A182IT71 A0A232ENI8 A0A182X3A6 A0A182F6R4 A0A182VCJ9 K7J4J2 A0A182HZF3 A0A1Q3FW40 A0A0C9R5N5 A0A336M6C3 A0A2M4BXI3 A0A2S2NFA3 A0A2M4AV17 C4WXW4 A0A1I8NTE7 F4WCS5 A0A151WML8 A0A2A3EI20 A0A195EE02 A0A151JWI3 A0A2M3ZCC0 A0A2M4BYH5 A0A1W4WHQ9 A0A2M4BX15 A0A139WGS2 A0A151I2T6 A0A158NIC5 A0A310S805 A0A026WDD4 A0A088AC21 A0A1I8N4L9 A0A0L7R9K7 A0A154PIM6 A0A1W4WTL0 A0A2M4CI09 A0A151IIH0 A0A0L0CI66 T1IXD2 B1GSA1 A0A1B0BT66 A0A1B0FQN0 A0A1W4WHS0 E2A8R4 A0A2M4ASS2 Q7QKB9 A0A1B6HUT6 A0A1A9WJD9 A0A1B6EQ58 E9IPQ7 E2BL77 A0A1I8NTE9 T1DPI8 A0A182PS61 A0A0K8TUW3 W5J624 A0A034WQB7 N6TTY7 A0A1I8N4M2 A0A1S4EAB3 J3JTM8 W8C5Q0 Q17DI7 B4N9B9 A0A182RH55 B3M0F4 A0A0A1XP63 A0A0R3NNA3 A0A2L2YE65 B4GEU0 B5DVG1 E9GJ15 A0A0K8TVV3 A0A3R7QCY2 F5HIT0 Q17DI7-2 A0A1W4UPK4 A0A164WG31 A0A0N7ZX73 A0A023EJZ4 A0A182GI56
A0A1B0CVF5 A0A1L8DG01 R4V4H2 A0A067R2N1 E0W3R8 A0A1W4WTW7 A0A182TGH7 A0A1Y1N426 A0A182NMN0 A0A3F2YX47 A0A182VQ18 A0A1S3CYS7 A0A182Y4R2 U5EIU3 A0A182IT71 A0A232ENI8 A0A182X3A6 A0A182F6R4 A0A182VCJ9 K7J4J2 A0A182HZF3 A0A1Q3FW40 A0A0C9R5N5 A0A336M6C3 A0A2M4BXI3 A0A2S2NFA3 A0A2M4AV17 C4WXW4 A0A1I8NTE7 F4WCS5 A0A151WML8 A0A2A3EI20 A0A195EE02 A0A151JWI3 A0A2M3ZCC0 A0A2M4BYH5 A0A1W4WHQ9 A0A2M4BX15 A0A139WGS2 A0A151I2T6 A0A158NIC5 A0A310S805 A0A026WDD4 A0A088AC21 A0A1I8N4L9 A0A0L7R9K7 A0A154PIM6 A0A1W4WTL0 A0A2M4CI09 A0A151IIH0 A0A0L0CI66 T1IXD2 B1GSA1 A0A1B0BT66 A0A1B0FQN0 A0A1W4WHS0 E2A8R4 A0A2M4ASS2 Q7QKB9 A0A1B6HUT6 A0A1A9WJD9 A0A1B6EQ58 E9IPQ7 E2BL77 A0A1I8NTE9 T1DPI8 A0A182PS61 A0A0K8TUW3 W5J624 A0A034WQB7 N6TTY7 A0A1I8N4M2 A0A1S4EAB3 J3JTM8 W8C5Q0 Q17DI7 B4N9B9 A0A182RH55 B3M0F4 A0A0A1XP63 A0A0R3NNA3 A0A2L2YE65 B4GEU0 B5DVG1 E9GJ15 A0A0K8TVV3 A0A3R7QCY2 F5HIT0 Q17DI7-2 A0A1W4UPK4 A0A164WG31 A0A0N7ZX73 A0A023EJZ4 A0A182GI56
PDB
5U0S
E-value=1.13747e-19,
Score=231
Ontologies
GO
PANTHER
Topology
Subcellular location
Nucleus
Length:
140
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.00662999999999999
Exp number, first 60 AAs:
0.00627
Total prob of N-in:
0.16338
outside
1 - 140
Population Genetic Test Statistics
Pi
189.374059
Theta
163.025464
Tajima's D
0.485677
CLR
0.167152
CSRT
0.508024598770061
Interpretation
Possibly Positive selection
