Gene

KWMTBOMO09617

Annotation

PREDICTED:_pickpocket_protein_28-like_[Bombyx_mori]

Location

Bomo_Chr16(+):5656814-5658298      View in EpiBrowser

Full name

Pickpocket protein 28      

Location in the cell

Extracellular   Reliability : 1.069 Mitochondrial   Reliability : 1.065 PlasmaMembrane   Reliability : 1.107

CDS

ATGCTGGTAGTGCACTTTTTCTTTGAAGACAACACCTTCTTGAGGTTCACAAAGGGTGAAATATTTGGACTAACAGAATTTTTATCGAACACGGGTGGCCTTCTAGGATTGTGTATGGGCTTCAGTATTATGAGTGCCGTAGAACTCATATACTACCTCACTCTCCGAGCGCTGTGCATGGCAAGACGACGTCCAAAGCATCCTTTCACTAATTAA

Protein

MLVVHFFFEDNTFLRFTKGEIFGLTEFLSNTGGLLGLCMGFSIMSAVELIYYLTLRALCMARRRPKHPFTN

Description

Osmosensitive ion channel that mediates the cellular and behavioral response to water. Plays an essential role in gustatory water reception. Part of a complex that plays a role in tracheal liquid clearance. Probable role in sodium transport.

Similarity

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.

Keywords

Cell membrane   Complete proteome   Ion channel   Ion transport   Membrane   Reference proteome   Sodium   Sodium channel   Sodium transport   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Pickpocket protein 28

Uniprot

A0A2A4JZR3   A0A437BIK4   A0A2H1V4S6   A0A026WH41   A0A3L8DZA0   A0A1I8NLF6   + More
A0A1B0ARX1   A0A1I8MB58   A0A1I8M676   B4NE18   A0A1A9YCN5   B4L1U3   A0A0P8Y7G7   B3N0C8   A0A1B0FNM8   A0A0L0C993   A0A0M9A038   A0A3B0J8E7   A0A1J1IXR0   Q29IB8   A0A1A9UHP7   B4M1J5   B4JL61   A0A2S2NS56   A0A0M5J642   A0A154PLS7   A0A1W4VHZ0   B4Q1W1   B3NW89   B4IEU0   A0A2J7PMQ8   B4R639   Q86LG1   A0A1B0GN28   A0A1B6MGD0   A0A158NBF0   A0A067RB77   A0A0C9RL33   A0A1S4EW92   A0A1A9WF90   A0A1D2MTK5   A0A232FIR5   B0WIZ9   K7IP12   A0A1D2N8C1   A0A226EXG1   A0A1I8N2I2   A0A1W4XR61   A0A1I8MQ88   A0A2W1BGB8   A0A139WCM4   B0WDC8   A0A226DYB2   A0A182GC76   B0WDC6   D6WXM7   A0A1D2MEU0   A0A226EYV0   A0A3S2NPU4   Q17NS9   A0A194PW83   A0A226F6M1   A0A1I8PEH0   A0A182MXN6   A0A1J1HMY9   A0A0L7L5Y6   A0A1Y1L465   Q17MX3   B0X0S1   A0A1I8PI06   N6U8E9   A0A1S4EX90   A0A182GRH0   T1H366   U4UGG3   Q9VS73   B4PC79   B3NFC4   A0A0J9RQW9   B4HV75   A0A182H7C8   A0A084WQC5   A0A1I8NHK4   B0WKI1   A0A1B0GL64   A0A226F2X9   A0A1S4G1A5   A0A226EYJ2   W5JCG6   B4J292   B3M5Z2   Q2M133   B4GUR0   A0A1B0GH50   A0A0L7LLW2   A0A0Q9WPD7   D6WXM6   A0A1I8N4A3   A0A182WEP1  

Pubmed

24508170    30249741    25315136    17994087    26108605    15632085    + More
17550304    12571352    10731132    12537572    12848938    20445050    20364123    21347285    24845553    17510324    27289101    28648823    20075255    28756777    18362917    19820115    26483478    26354079    26227816    28004739    23537049    12537568    12537573    12537574    16110336    17569856    17569867    22936249    24438588    20920257    23761445   

EMBL

NWSH01000320    PCG77501.1    RSAL01000051    RVE50284.1    ODYU01000646    SOQ35776.1    + More
KK107250    EZA54394.1    QOIP01000002    RLU25553.1    JXJN01002618    CH964239    EDW81987.1    CH933810    EDW06746.1    CH902640    KPU77367.1    EDV38332.1    CCAG010007674    JRES01000741    KNC28817.1    KQ435803    KOX73079.1    OUUW01000003    SPP78135.1    CVRI01000064    CRL05059.1    CH379063    EAL32735.2    CH940651    EDW65549.1    CH916370    EDW00314.1    GGMR01007365    MBY19984.1    CP012528    ALC49086.1    KQ434948    KZC12404.1    CM000162    EDX02536.1    CH954180    EDV46428.1    CH480832    EDW46194.1    NEVH01023960    PNF17623.1    CM000366    EDX18143.1    AY226552    AY226553    AE014298    BT122074    AAF48671.3    AAO47378.1    ADE06680.1    AJVK01027922    AJVK01027923    AJVK01027924    GEBQ01005015    JAT34962.1    ADTU01000293    KK852572    KDR21106.1    GBYB01008935    JAG78702.1    LJIJ01000549    ODM96336.1    NNAY01000169    OXU30358.1    DS231954    EDS28860.1    LJIJ01000149    ODN01494.1    LNIX01000001    OXA61306.1    KZ150082    PZC73838.1    KQ971362    KYB25718.1    DS231896    EDS44441.1    LNIX01000009    OXA50442.1    JXUM01054684    KQ561832    KXJ77400.1    EDS44439.1    EFA08874.1    LJIJ01001558    ODM91404.1    OXA61991.1    RSAL01000014    RVE53205.1    CH477196    EAT48395.1    KQ459591    KPI97019.1    OXA64506.1    CVRI01000004    CRK87601.1    JTDY01002789    KOB70726.1    GEZM01065387    JAV68489.1    CH477203    EAT48029.1    DS232244    EDS38313.1    APGK01038999    APGK01039000    KB740966    ENN76926.1    JXUM01082415    KQ563311    KXJ74085.1    CAQQ02171020    KB632186    ERL89696.1    AE014296    AAF50555.3    CM000159    EDW93764.1    CH954178    EDV50466.2    CM002912    KMY98102.1    CH480817    EDW50846.1    JXUM01116018    KQ565940    KXJ70514.1    ATLV01025482    KE525389    KFB52419.1    DS231972    EDS29857.1    AJWK01034404    AJWK01034405    OXA63838.1    OXA62672.1    ADMH02001572    ETN62032.1    CH916366    EDV97043.1    CH902618    EDV40708.1    CH379069    EAL30743.2    CH479191    EDW26343.1    AJWK01003969    AJWK01003970    AJWK01003971    AJWK01003972    JTDY01000591    KOB76548.1    KRF94123.1    EFA08873.2   

Proteomes

UP000218220    UP000283053    UP000053097    UP000279307    UP000095300    UP000092460    + More
UP000095301    UP000007798    UP000092443    UP000009192    UP000007801    UP000092444    UP000037069    UP000053105    UP000268350    UP000183832    UP000001819    UP000078200    UP000008792    UP000001070    UP000092553    UP000076502    UP000192221    UP000002282    UP000008711    UP000001292    UP000235965    UP000000304    UP000000803    UP000092462    UP000005205    UP000027135    UP000091820    UP000094527    UP000215335    UP000002320    UP000002358    UP000198287    UP000192223    UP000007266    UP000069940    UP000249989    UP000008820    UP000053268    UP000075884    UP000037510    UP000019118    UP000015102    UP000030742    UP000030765    UP000092461    UP000000673    UP000008744    UP000075920   

PRIDE

Q86LG1    Q9VS73   

Pfam

PF00858   ASC        + More
PF00271   Helicase_C
PF00270   DEAD
PF11838   ERAP1_C
PF01433   Peptidase_M1

Interpro

IPR001873   ENaC        + More
IPR020903   ENaC_CS       
IPR027417   P-loop_NTPase       
IPR014001   Helicase_ATP-bd       
IPR001650   Helicase_C       
IPR014014   RNA_helicase_DEAD_Q_motif       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR042097   Aminopeptidase_N-like_N       
IPR014782   Peptidase_M1_dom       
IPR024571   ERAP1-like_C_dom       
IPR033581   APN2       
IPR001930   Peptidase_M1       
IPR034016   M1_APN-typ       

SUPFAM

SSF52540   SSF52540       

Gene 3D

2.60.40.1730    

CDD

cd00079  HELICc
cd09601  M1_APN_2

ProteinModelPortal

A0A2A4JZR3   A0A437BIK4   A0A2H1V4S6   A0A026WH41   A0A3L8DZA0   A0A1I8NLF6   + More
A0A1B0ARX1   A0A1I8MB58   A0A1I8M676   B4NE18   A0A1A9YCN5   B4L1U3   A0A0P8Y7G7   B3N0C8   A0A1B0FNM8   A0A0L0C993   A0A0M9A038   A0A3B0J8E7   A0A1J1IXR0   Q29IB8   A0A1A9UHP7   B4M1J5   B4JL61   A0A2S2NS56   A0A0M5J642   A0A154PLS7   A0A1W4VHZ0   B4Q1W1   B3NW89   B4IEU0   A0A2J7PMQ8   B4R639   Q86LG1   A0A1B0GN28   A0A1B6MGD0   A0A158NBF0   A0A067RB77   A0A0C9RL33   A0A1S4EW92   A0A1A9WF90   A0A1D2MTK5   A0A232FIR5   B0WIZ9   K7IP12   A0A1D2N8C1   A0A226EXG1   A0A1I8N2I2   A0A1W4XR61   A0A1I8MQ88   A0A2W1BGB8   A0A139WCM4   B0WDC8   A0A226DYB2   A0A182GC76   B0WDC6   D6WXM7   A0A1D2MEU0   A0A226EYV0   A0A3S2NPU4   Q17NS9   A0A194PW83   A0A226F6M1   A0A1I8PEH0   A0A182MXN6   A0A1J1HMY9   A0A0L7L5Y6   A0A1Y1L465   Q17MX3   B0X0S1   A0A1I8PI06   N6U8E9   A0A1S4EX90   A0A182GRH0   T1H366   U4UGG3   Q9VS73   B4PC79   B3NFC4   A0A0J9RQW9   B4HV75   A0A182H7C8   A0A084WQC5   A0A1I8NHK4   B0WKI1   A0A1B0GL64   A0A226F2X9   A0A1S4G1A5   A0A226EYJ2   W5JCG6   B4J292   B3M5Z2   Q2M133   B4GUR0   A0A1B0GH50   A0A0L7LLW2   A0A0Q9WPD7   D6WXM6   A0A1I8N4A3   A0A182WEP1  

KEGG

101740294    K03440 acid-sensing ion channel, other | (RefSeq) pickpocket protein 28-like

GO

GO:0016021   GO:0005272   GO:0071462   GO:0035002   GO:0042756   GO:0005886   GO:0009415   GO:0006814   GO:0005524   GO:0003676   GO:0008270   GO:0008237   GO:0035179   GO:0032590   GO:0050966   GO:0016020   GO:0043565   GO:0016742   GO:0005737   GO:0006730   GO:0009258   GO:0016155   GO:0003824  

PANTHER

PTHR11690   PTHR11533:SF246  

Subcellular location

Cell membrane  

Length:

71

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.88583

Exp number, first 60 AAs:

22.88519

Total prob of N-in:

0.00340

POSSIBLE N-term signal

sequence

outside

1  -  32

TMhelix

33  -  55

inside

56  -  71

 

 

Pi

126.794455

Theta

121.982349

Tajima's D

-0.339952

CLR

0.053702

CSRT

0.28053597320134

Interpretation

Uncertain