Gene

KWMTBOMO09615

Pre Gene Modal

BGIBMGA012849

Annotation

PREDICTED:_sodium_channel_protein_Nach-like_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr16(+):5649394-5650798      View in EpiBrowser

Full name

Pickpocket protein 28      

Location in the cell

PlasmaMembrane   Reliability : 2.24

CDS

ATGACCAAAATTCAACAAGCCCCACAATCAAAGAACCAAAGTTTAGATGACGAAGAACCTCTGTCTTTTGCGAGTGACATAAGGCAATATCTACAATGTTCCACGTTGCACGGTCTTCGGTATATTGCCGAGAAGAAACTGACTTGGTTCGAAAGGTTCTTCTGGCTGGCAGCTTTTAGCTCCTCCTTAATTTGCGCTGGATTCTTTATTCTAAACGTGTATTCGAAATGGCGGATGTCGCCAATGATAGTGAGCATCAATCCTGAAAATATGCCTTTGCATGGCTTGCCTTTCCCAGCTATAACCATTTGCAATGTTAATCAAGCAAAGAAATCTATCGCCGAAGGATACCAAAAATACGGGTGA

Protein

MTKIQQAPQSKNQSLDDEEPLSFASDIRQYLQCSTLHGLRYIAEKKLTWFERFFWLAAFSSSLICAGFFILNVYSKWRMSPMIVSINPENMPLHGLPFPAITICNVNQAKKSIAEGYQKYG

Description

Osmosensitive ion channel that mediates the cellular and behavioral response to water. Plays an essential role in gustatory water reception. Part of a complex that plays a role in tracheal liquid clearance. Probable role in sodium transport.

Similarity

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Keywords

Cell membrane   Complete proteome   Ion channel   Ion transport   Membrane   Reference proteome   Sodium   Sodium channel   Sodium transport   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Pickpocket protein 28

Uniprot

A0A2H1V4S6   A0A437BIK4   A0A2A4JZR3   A0A212FML8   A0A0N1PJJ9   A0A0N1PJY5   + More
N6T2I8   U4U735   E2BNL2   A0A226DRB1   B3N2P2   A0A182YAL4   A0A0M5J642   E9IWN6   F4X372   W5J1E9   A0A2S2R4W4   A0A182GC76   A0A151WEN4   B3NW89   A0A0L7QMQ9   A0A195BDN0   A0A067RB77   A0A1I8NLF6   B4JL61   J9LZ57   A0A1B0ARX1   A0A158NBF0   B4IEU0   B4R639   A0A2A3EG41   A0A182IM43   A0A154PLS7   A0A0M9A038   B3N0C8   A0A0P8Y7G7   A0A1W4XBD2   E2A269   B4P7Y1   B4QH60   A0A182WSG5   A0A1A9YCN5   A0A088A4H4   A0A182Q3R4   A0A0J9RIX3   A0A182VK33   B3NNP7   B4I849   A0A0P6A4R8   A0A1B0ABX7   A0A0P5ZYH3   Q7PKT6   A0A182HLB5   Q8T5H4   A0A1B0FNM8   A0A182KFD0   A0A195FFW2   A0A3B0J8E7   D7EL39   A0A2P8XRE9   A0A232FIR5   A0A1A9WF90   A0A0L0C993   A0A182L9P3   Q8MU73   A0A1A9UHP7   A0A182UKS5   A0A1W4VP24   Q9W250   A0A182FA76   B4L1U3   A0A226DRR1   A0A0P6CR49   A0A182VZA7   A0A3Q0J677   A0A1W4VHZ0   A0A164V2P5   A0A182R635   A0A0L0CLL3   A0A182PGQ2   A0A0P6HZM3   Q17NS9   A0A182NS56   K7IP12   A0A1S4EW92   Q86LG1   A0A182TA96   A0A182MTE6   A0A026WH41   A0A1B0GH45   A0A3L8DZA0   A0A2P8Z373   A0A1J1IXR0   A0A0A9XE52   A0A1I8MUU6   B4M1J5   B4Q1W1  

Pubmed

22118469    26354079    23537049    20798317    17994087    25244985    + More
21282665    21719571    20920257    23761445    26483478    24845553    21347285    17550304    22936249    12364791    14747013    17210077    12060762    18362917    19820115    29403074    28648823    26108605    20966253    10731132    12537568    12537572    12537573    12537574    12571352    16110336    17569856    17569867    26109357    26109356    17510324    20075255    12848938    20445050    20364123    24508170    30249741    25401762    25315136   

EMBL

ODYU01000646    SOQ35776.1    RSAL01000051    RVE50284.1    NWSH01000320    PCG77501.1    + More
AGBW02007651    OWR54981.1    LADI01006439    KPJ20638.1    KQ460208    KPJ16605.1    APGK01054977    KB741256    ENN71763.1    KB631749    ERL85770.1    GL449414    EFN82791.1    LNIX01000013    OXA47207.1    CH905151    EDV29966.2    CP012528    ALC49086.1    GL766597    EFZ14977.1    GL888609    EGI59053.1    ADMH02002183    ETN57987.1    GGMS01015801    MBY85004.1    JXUM01054684    KQ561832    KXJ77400.1    KQ983238    KYQ46255.1    CH954180    EDV46428.1    KQ414885    KOC59880.1    KQ976509    KYM82676.1    KK852572    KDR21106.1    CH916370    EDW00314.1    ABLF02032360    ABLF02032364    JXJN01002618    ADTU01000293    CH480832    EDW46194.1    CM000366    EDX18143.1    KZ288266    PBC30262.1    KQ434948    KZC12404.1    KQ435803    KOX73079.1    CH902640    EDV38332.1    KPU77367.1    GL435922    EFN72474.1    CM000158    EDW92136.1    CM000362    EDX08206.1    AXCN02000266    CM002911    KMY95792.1    CH954179    EDV55604.1    CH480824    EDW56774.1    GDIP01039413    JAM64302.1    GDIP01037965    JAM65750.1    AAAB01008987    EAA43142.2    APCN01000890    AJ439398    CAD28127.1    CCAG010007674    KQ981606    KYN39585.1    OUUW01000003    SPP78135.1    KQ973192    EFA11834.2    PYGN01001481    PSN34583.1    NNAY01000169    OXU30358.1    JRES01000741    KNC28817.1    AJ441131    CAD29634.1    AE013599    AY226543    AAF46849.2    AAO47369.1    CH933810    EDW06746.1    OXA47357.1    GDIP01004478    JAM99237.1    LRGB01001463    KZS11907.1    JRES01000319    KNC32334.1    GDIQ01011901    JAN82836.1    CH477196    EAT48395.1    AY226552    AY226553    AE014298    BT122074    AAF48671.3    AAO47378.1    ADE06680.1    AXCM01013744    AXCM01013745    KK107250    EZA54394.1    AJWK01003962    AJWK01003963    AJWK01003964    QOIP01000002    RLU25553.1    PYGN01000218    PSN50939.1    CVRI01000064    CRL05059.1    GBHO01025335    JAG18269.1    CH940651    EDW65549.1    CM000162    EDX02536.1   

Proteomes

UP000283053    UP000218220    UP000007151    UP000053268    UP000053240    UP000019118    + More
UP000030742    UP000008237    UP000198287    UP000007801    UP000076408    UP000092553    UP000007755    UP000000673    UP000069940    UP000249989    UP000075809    UP000008711    UP000053825    UP000078540    UP000027135    UP000095300    UP000001070    UP000007819    UP000092460    UP000005205    UP000001292    UP000000304    UP000242457    UP000075880    UP000076502    UP000053105    UP000192223    UP000000311    UP000002282    UP000076407    UP000092443    UP000005203    UP000075886    UP000075903    UP000092445    UP000007062    UP000075840    UP000092444    UP000075881    UP000078541    UP000268350    UP000007266    UP000245037    UP000215335    UP000091820    UP000037069    UP000075882    UP000078200    UP000075902    UP000192221    UP000000803    UP000069272    UP000009192    UP000075920    UP000079169    UP000076858    UP000075900    UP000075885    UP000008820    UP000075884    UP000002358    UP000075901    UP000075883    UP000053097    UP000092461    UP000279307    UP000183832    UP000095301    UP000008792   

PRIDE

Q9W250    Q86LG1   

Pfam

PF00858   ASC        + More
PF07885   Ion_trans_2
PF00271   Helicase_C
PF00270   DEAD

Interpro

IPR001873   ENaC        + More
IPR003280   2pore_dom_K_chnl       
IPR013099   K_chnl_dom       
IPR020903   ENaC_CS       
IPR027417   P-loop_NTPase       
IPR014001   Helicase_ATP-bd       
IPR001650   Helicase_C       
IPR014014   RNA_helicase_DEAD_Q_motif       
IPR011545   DEAD/DEAH_box_helicase_dom       

SUPFAM

SSF52540   SSF52540       

CDD

cd00079  HELICc

ProteinModelPortal

A0A2H1V4S6   A0A437BIK4   A0A2A4JZR3   A0A212FML8   A0A0N1PJJ9   A0A0N1PJY5   + More
N6T2I8   U4U735   E2BNL2   A0A226DRB1   B3N2P2   A0A182YAL4   A0A0M5J642   E9IWN6   F4X372   W5J1E9   A0A2S2R4W4   A0A182GC76   A0A151WEN4   B3NW89   A0A0L7QMQ9   A0A195BDN0   A0A067RB77   A0A1I8NLF6   B4JL61   J9LZ57   A0A1B0ARX1   A0A158NBF0   B4IEU0   B4R639   A0A2A3EG41   A0A182IM43   A0A154PLS7   A0A0M9A038   B3N0C8   A0A0P8Y7G7   A0A1W4XBD2   E2A269   B4P7Y1   B4QH60   A0A182WSG5   A0A1A9YCN5   A0A088A4H4   A0A182Q3R4   A0A0J9RIX3   A0A182VK33   B3NNP7   B4I849   A0A0P6A4R8   A0A1B0ABX7   A0A0P5ZYH3   Q7PKT6   A0A182HLB5   Q8T5H4   A0A1B0FNM8   A0A182KFD0   A0A195FFW2   A0A3B0J8E7   D7EL39   A0A2P8XRE9   A0A232FIR5   A0A1A9WF90   A0A0L0C993   A0A182L9P3   Q8MU73   A0A1A9UHP7   A0A182UKS5   A0A1W4VP24   Q9W250   A0A182FA76   B4L1U3   A0A226DRR1   A0A0P6CR49   A0A182VZA7   A0A3Q0J677   A0A1W4VHZ0   A0A164V2P5   A0A182R635   A0A0L0CLL3   A0A182PGQ2   A0A0P6HZM3   Q17NS9   A0A182NS56   K7IP12   A0A1S4EW92   Q86LG1   A0A182TA96   A0A182MTE6   A0A026WH41   A0A1B0GH45   A0A3L8DZA0   A0A2P8Z373   A0A1J1IXR0   A0A0A9XE52   A0A1I8MUU6   B4M1J5   B4Q1W1  

PDB

6AVE     E-value=0.0001208,     Score=101

KEGG

101740294    K03440 acid-sensing ion channel, other | (RefSeq) pickpocket protein 28-like

GO

GO:0016021   GO:0005272   GO:0005267   GO:0035002   GO:0071462   GO:0042756   GO:0005524   GO:0003676   GO:0006814   GO:0005886   GO:0009415   GO:0016020   GO:0043565   GO:0016742   GO:0005737   GO:0006730   GO:0009258   GO:0016155   GO:0003824  

PANTHER

PTHR11690  

Subcellular location

Cell membrane  

Length:

121

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.66604

Exp number, first 60 AAs:

8.20068

Total prob of N-in:

0.54752

outside

1  -  52

TMhelix

53  -  75

inside

76  -  121

 

 

Pi

235.68783

Theta

201.70917

Tajima's D

0.510794

CLR

0.047479

CSRT

0.516174191290436

Interpretation

Uncertain