Gene

KWMTBOMO09591  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012838

Annotation

hypothetical_protein_KGM_15447_[Danaus_plexippus]

Location

Bomo_Chr16(+):4895569-4953301      View in EpiBrowser

Full name

Flotillin-2      

Location in the cell

Cytoplasmic   Reliability : 2.601

CDS

ATGTACGCGCTTGTAATATATGTACATTTAAGTGGCTGTTTCGGGCCGACCACGAAACGTACCATAGTGGGTGGATGGGCATGGGCCTGGTGTCTGGTTACGGACGTCCAACGTATATCCCTTGAAGTGATGACATTGAACCCGATGTGCGAGTACGTTGAAACGGCCCAAGGAGTGCCGCTCACGGTGACCGGAGTCGCCCAGTGCAAGATCATGAACGAAGACGAACTTCTCACAACTGCCTGCGAGCAGTTCCTGGGCAAGACCGTCAAAGAGATTAAGATGACTGTCCTGCAAACGTTGGAGGGTCATTTGCGAGCTATTCTCGGAACTCTTACAGTAGAAGAGGTGTACAAAGACAGGGACCAATTCGCGGGCTTGGTACGCGAAGTGGCTGCGCCGGACGTCGGAAGAATGGGAATCGAGATTCTGTCCTTCACGATTAAGGACGTCTACGACGATGTCCAGTATCTGGCCAGCTTGGGGAAGTCGCAGACGGCCAACGTGAAGAGGGACGCTGACGTCGGTGTCGCTCTGGCTAACCGAGATGCTGGTATTAGGGAAGCGGAATGTGAGAAAAACGCAATGGACGTCAAATATTCGATGGACACCAAAATAGAAGACAACACGAGACTCTTCAAACTACAGAAGGCGCAGTTTGATCAAGAAATAAACACAGCTAAAGCGGAAGCGGCTTTGGCTTACGAACTGCAAGCAGCGAAAATAAAACAGAGAATCCGAAACGAAGAGATACAAATCGAAGTCGTCGAGCGTCGTAAGCAAATAGAAGTGGAGCAACAAGAAATCCAACGCAGGGAGGAAGAACTGATAGCGACAGTGCGTCTGCCAGCCGAGGCGGAGGCTTACCGTCTGCAAACAATCGCTGAAGGAAAACGTACTCAAACTGTTGAGGCAGCTAAGGCGGACGCGGAACGCATCAAGGTTCTGGGATTGGCTGAAGCGACGGCCATCGGGGACGTGGGCAAAGCTGACGCCGAGAGGATGCTGGCCAAGGCTAAAGTCTACAAGCAGTATGGCGATGCGGCTATTATGGCCCTCGTTCTCGAAGCGCTGCCAAAGATCGCGGCAGAAGTGTCGGCTCCATTAGCGAAGACGGACGAGATAGTCCTGGTAGGAGACAACGGAACCACCGGAGACGTGGCTCGTCTCGCGAGCGGGATCCCGCCGGCCCTGAAGACTCTCACCGGCTTAGACCTGACACAGGTGCTGAAACGTTTGCACCCGACCGGCGGAGAAGAGACGAACCTTGCAGCTGCCGCAACCAAGAAGAAGGAAGTCGTAGCTTTCTAA

Protein

MYALVIYVHLSGCFGPTTKRTIVGGWAWAWCLVTDVQRISLEVMTLNPMCEYVETAQGVPLTVTGVAQCKIMNEDELLTTACEQFLGKTVKEIKMTVLQTLEGHLRAILGTLTVEEVYKDRDQFAGLVREVAAPDVGRMGIEILSFTIKDVYDDVQYLASLGKSQTANVKRDADVGVALANRDAGIREAECEKNAMDVKYSMDTKIEDNTRLFKLQKAQFDQEINTAKAEAALAYELQAAKIKQRIRNEEIQIEVVERRKQIEVEQQEIQRREEELIATVRLPAEAEAYRLQTIAEGKRTQTVEAAKADAERIKVLGLAEATAIGDVGKADAERMLAKAKVYKQYGDAAIMALVLEALPKIAAEVSAPLAKTDEIVLVGDNGTTGDVARLASGIPPALKTLTGLDLTQVLKRLHPTGGEETNLAAAATKKKEVVAF

Subunit

Heterooligomeric complex of flotillins 1 and 2.

Similarity

Belongs to the band 7/mec-2 family. Flotillin subfamily.

Keywords

Alternative splicing   Cell adhesion   Complete proteome   Membrane   Reference proteome  

Feature

chain  Flotillin-2
splice variant  In isoform D.

Uniprot

A0A212FMM8   A0A194RF81   A0A194PTC8   A0A437BIK5   A0A1L8DVT2   A0A1Y9H200   + More
U5EJH9   A0A1Q3G2Y0   A0A0P6K119   A0A1Q3G310   A0A084VW99   A0A1Q3G341   A0A1Q3G2X6   Q7PS74   A0A182LWD9   A0A182QB08   A0A0K8UAL8   A0A034W8L1   A0A0A1WQS1   W8B3J0   A0A1B6LSG3   A0A0M4F8S7   A0A1Q3EUP1   A0A2M3Z1E5   A0A2M4A593   A0A2M4CV16   A0A1B6IRS0   A0A1B6FYQ0   A0A182I8U3   A0A182LAR1   A0A0K8WI30   M9PJN2   A0A1B0GIG0   O61492-2   A4V4F2   B4L258   A0A023F4T6   A0A0N7Z922   A0A069DTR6   B4JL03   T1I448   A0A182XXE9   A0A3B0J8Z2   A0A1I8P084   M9PHT0   A0A0R1EA44   A0A0Q5T7S2   B3NUW7   B4R4W4   A0A0R3NYH7   B4PW75   B4IJ66   F2FB46   O61492   B5DL99   B4HAK5   B3MXJ8   A0A0R3NYQ1   A0A336LQB8   M9PHL7   A0A1I8P074   A0A0A9YIN1   E9G8K8   A0A164Q7Q5   A0A0P5SVA0   X1WI63   A0A0C9RDJ4   K7J273   A0A182IZA8   A0A3L8D6G9   A0A224XRZ8   A0A195BBJ6   E2BJJ6   A0A026WCZ5   A0A3S3PUS0   A0A2A3EHU8   A0A158NUQ7   A0A151J2Y5   V5GLL6   A0A0P6ERE0   A0A0P6ER11   A0A151I6J8   A0A088AJY9   A0A0J7NK35   A0A1Y1LL80   A0A087UTP6   A0A443SKW2   E2ASE6   A0A0P6ATN3   R7UT48   A0A1V9X659   A0A2P6KIE5   A0A310SHM1   A0A2J7RBH4   A0A224YMX3   A0A131Z0G4   B4MT94   A0A1E1XBJ8   A0A293LP49   Q1MXG0  

Pubmed

22118469    26354079    26999592    24438588    12364791    14747013    + More
17210077    25348373    25830018    24495485    20966253    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    9573373    17994087    25474469    27129103    26334808    25244985    17550304    15632085    26109357    26109356    25401762    21292972    20075255    30249741    20798317    24508170    21347285    28004739    23254933    28327890    28797301    26830274    28503490    16724321   

EMBL

AGBW02007651    OWR55002.1    KQ460323    KPJ15960.1    KQ459595    KPI96019.1    + More
RSAL01000051    RVE50261.1    GFDF01003533    JAV10551.1    GANO01002227    JAB57644.1    GFDL01000867    JAV34178.1    GDUN01000316    JAN95603.1    GFDL01000899    JAV34146.1    ATLV01017524    ATLV01017525    ATLV01017526    KE525172    KFB42243.1    GFDL01000886    JAV34159.1    GFDL01000892    JAV34153.1    AAAB01008844    EAA06055.6    AXCM01001592    AXCM01001593    AXCN02000039    GDHF01028939    GDHF01028887    GDHF01014726    GDHF01009275    JAI23375.1    JAI23427.1    JAI37588.1    JAI43039.1    GAKP01008321    GAKP01008320    JAC50632.1    GBXI01013457    JAD00835.1    GAMC01018730    GAMC01018729    JAB87826.1    GEBQ01013354    JAT26623.1    CP012528    ALC48837.1    GFDL01016006    JAV19039.1    GGFM01001599    MBW22350.1    GGFK01002561    MBW35882.1    GGFL01005016    MBW69194.1    GECU01018098    JAS89608.1    GECZ01030108    GECZ01014452    JAS39661.1    JAS55317.1    APCN01003121    GDHF01029278    GDHF01001503    JAI23036.1    JAI50811.1    AE014298    AGB95396.1    AJWK01014066    AJWK01014067    AJWK01014068    AJWK01014069    AJWK01014070    AY069755    BT009962    AF044916    AAN09344.1    CH933810    EDW06798.2    GBBI01002241    JAC16471.1    GDKW01001755    JAI54840.1    GBGD01001574    JAC87315.1    CH916370    EDW00256.1    ACPB03007746    OUUW01000003    SPP78667.1    AGB95394.1    CM000162    KRK06312.1    CH954180    KQS30328.1    EDV47065.1    CM000366    EDX17921.1    CH379063    KRT06123.1    EDX01706.1    CH480847    EDW51045.1    BT126133    ADZ49071.1    AGB95397.1    EDY72298.1    CH479242    EDW37616.1    CH902630    EDV38463.1    KRT06122.1    UFQS01000042    UFQT01000042    SSW98353.1    SSX18739.1    AGB95395.1    GBHO01016125    GBHO01016087    GBHO01015299    GBHO01012128    GBRD01011886    JAG27479.1    JAG27517.1    JAG28305.1    JAG31476.1    JAG53938.1    GL732535    EFX84251.1    LRGB01002451    KZS07506.1    GDIP01135304    JAL68410.1    ABLF02038148    ABLF02038150    ABLF02056862    GBYB01006360    JAG76127.1    AAZX01003729    QOIP01000012    RLU15836.1    GFTR01005645    JAW10781.1    KQ976532    KYM81569.1    GL448571    EFN84153.1    KK107261    EZA53945.1    NCKU01002933    RWS08517.1    KZ288238    PBC31355.1    ADTU01026677    ADTU01026678    ADTU01026679    KQ980314    KYN16686.1    GALX01003517    JAB64949.1    GDIQ01072514    JAN22223.1    GDIQ01072515    JAN22222.1    KQ978473    KYM93716.1    LBMM01004060    KMQ92850.1    GEZM01052565    JAV74434.1    KK121567    KFM80735.1    NCKV01001537    RWS28167.1    GL442298    EFN63612.1    GDIP01024963    JAM78752.1    AMQN01007193    KB300180    ELU07072.1    MNPL01023185    OQR68861.1    MWRG01011212    PRD26074.1    KQ766578    OAD53689.1    NEVH01005904    PNF38186.1    GFPF01007821    MAA18967.1    GEDV01004601    JAP83956.1    CH963851    EDW75333.2    GFAC01002609    JAT96579.1    GFWV01005742    MAA30472.1    AB112548    BAE93513.1   

Proteomes

UP000007151    UP000053240    UP000053268    UP000283053    UP000075884    UP000030765    + More
UP000007062    UP000075883    UP000075886    UP000092553    UP000075840    UP000075882    UP000000803    UP000092461    UP000009192    UP000001070    UP000015103    UP000076408    UP000268350    UP000095300    UP000002282    UP000008711    UP000000304    UP000001819    UP000001292    UP000008744    UP000007801    UP000000305    UP000076858    UP000007819    UP000002358    UP000075880    UP000279307    UP000078540    UP000008237    UP000053097    UP000285301    UP000242457    UP000005205    UP000078492    UP000078542    UP000005203    UP000036403    UP000054359    UP000288716    UP000000311    UP000014760    UP000192247    UP000235965    UP000007798   

PRIDE

O61492    A4V4F2    M9PHT0   

Pfam

PF15975   Flot        + More
PF01145   Band_7
PF00732   GMC_oxred_N

Interpro

IPR036013   Band_7/SPFH_dom_sf        + More
IPR027705   Flotillin_fam       
IPR031905   Flotillin_C       
IPR001107   Band_7       
IPR000014   PAS       
IPR000172   GMC_OxRdtase_N       

SUPFAM

SSF117892   SSF117892       

ProteinModelPortal

A0A212FMM8   A0A194RF81   A0A194PTC8   A0A437BIK5   A0A1L8DVT2   A0A1Y9H200   + More
U5EJH9   A0A1Q3G2Y0   A0A0P6K119   A0A1Q3G310   A0A084VW99   A0A1Q3G341   A0A1Q3G2X6   Q7PS74   A0A182LWD9   A0A182QB08   A0A0K8UAL8   A0A034W8L1   A0A0A1WQS1   W8B3J0   A0A1B6LSG3   A0A0M4F8S7   A0A1Q3EUP1   A0A2M3Z1E5   A0A2M4A593   A0A2M4CV16   A0A1B6IRS0   A0A1B6FYQ0   A0A182I8U3   A0A182LAR1   A0A0K8WI30   M9PJN2   A0A1B0GIG0   O61492-2   A4V4F2   B4L258   A0A023F4T6   A0A0N7Z922   A0A069DTR6   B4JL03   T1I448   A0A182XXE9   A0A3B0J8Z2   A0A1I8P084   M9PHT0   A0A0R1EA44   A0A0Q5T7S2   B3NUW7   B4R4W4   A0A0R3NYH7   B4PW75   B4IJ66   F2FB46   O61492   B5DL99   B4HAK5   B3MXJ8   A0A0R3NYQ1   A0A336LQB8   M9PHL7   A0A1I8P074   A0A0A9YIN1   E9G8K8   A0A164Q7Q5   A0A0P5SVA0   X1WI63   A0A0C9RDJ4   K7J273   A0A182IZA8   A0A3L8D6G9   A0A224XRZ8   A0A195BBJ6   E2BJJ6   A0A026WCZ5   A0A3S3PUS0   A0A2A3EHU8   A0A158NUQ7   A0A151J2Y5   V5GLL6   A0A0P6ERE0   A0A0P6ER11   A0A151I6J8   A0A088AJY9   A0A0J7NK35   A0A1Y1LL80   A0A087UTP6   A0A443SKW2   E2ASE6   A0A0P6ATN3   R7UT48   A0A1V9X659   A0A2P6KIE5   A0A310SHM1   A0A2J7RBH4   A0A224YMX3   A0A131Z0G4   B4MT94   A0A1E1XBJ8   A0A293LP49   Q1MXG0  

PDB

1WIN     E-value=1.32062e-51,     Score=513

KEGG

101741968    K07192 flotillin | (RefSeq) flotillin-2

GO

GO:0007155   GO:0035593   GO:0005829   GO:0005198   GO:0005737   GO:0035011   GO:0061357   GO:0016600   GO:0005886   GO:0016614   GO:0050660  

PANTHER

PTHR13806  

Subcellular location

Membrane   In neuronal cells, associated with GPI-anchored cell-adhesion molecules.   With evidence from 1 publications.

Length:

436

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.11682

Exp number, first 60 AAs:

0.11458

Total prob of N-in:

0.00806

outside

1  -  436

 

 

Pi

256.365727

Theta

173.938576

Tajima's D

2.038298

CLR

0.293512

CSRT

0.888455577221139

Interpretation

Uncertain