Gene

KWMTBOMO09558

Pre Gene Modal

BGIBMGA012830

Annotation

PREDICTED:_phosphatidylinositol_4-kinase_alpha_[Bombyx_mori]

Location

Bomo_Chr16(+):4161056-4178675      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 1.115 Nuclear   Reliability : 1.03 PlasmaMembrane   Reliability : 1.258

CDS

ATGTACAATCATTGGCATCCAAGCCAATCACTGTACCACTATACAAGAAAAAATACAGTGATTGGCACCAAAGAAATTACCGGTTCAAAACTGGAGCCCCGACCTCCGTTCGTGGCCCCGCACGCGGTGTGGGTCCGCTACTTGTGCGAAGTGGCGGAGACCGCCAAATACAACAGCCAGGAGAAGGTCGAGATGCTGGCGAGCCTGCTGCACCGATCTTTGCCGATCACTGTGGGCGATTACCGCGATCACATAAACAGACACGTCGAAGCAGTCGGAGTCAGATTCAAACTCCTCTCGTGCGGTCTCTCTTTACTGCAAGGCGACATACTGCCGCGCTCGCTGGCCAGGAACATACTCCGCGAACGCGTGTACAGCGCCTGCTTGGACTACTTCTGCCGAGGGATCCAGTGCCCGTCGAAAAGCTCCGGAGCTTTACGAGAAGATATCATATCGTTGATAAAGTTCTGGCAGCTCATGCACTCGGATAAGAAGTACTTGAAGAGCAGCGATATAGGTGGTGAATACGAGCTGATGGGTCCGAGCAGCCAGCAGAGCCTCTACACGTCGAACTCGCCCACGGACAACAGGTCGTCGGTGAACAGCAGCGACATCGGCAGCCGTCAGACCACGGGCTGGATCAACACGGTACCAATGTCCACGACCACGCTGAGCAGCGGAGCGGGTAGCATAGCGGGGAAACGATCTAACCGAAGCGTCAAGCCACCCGTCAAGCAACAGGACACGTACGTCAAGGACTACGTCAGGAAAAGGAATCTTATATTGGAGCTTATGGCGGTCGAGATAGAGTTCTTGGTGACGTGGCACAACCCTCACGGGCGGCCCGAGCAGGCCGTCCCGGGTGAGGACAACATCGCCACCTGGCGCTCCAAGCCCAACACCGAGCGGACCTGGAGGGACCACGCCAAGCTGGCCTGGGAAATCAGTCCCGTTCTCGCCGTCTTCATGCCGGAGAGGCTAAAGAACGACGGTATAGTGGCGGAGGTCAGACGCAAAGTCCAAGCGCAGCCGACCGCGGTGTGCCACGTCCCCCAGGCCCTGAAGTATCTGGTCACCACCGAAACCTTACTCAACGATGCGCAAGAGCTGGTACACATGATAACCTGGGCCCGGGTCAGTCCGGTGGAGGCCCTGTCGTACTTCAGCCGGCAGTACCCGCCGCACCCGCTGTCGGCGCAGGCGGCCGTCAACACGCTGACGTCATACCCCTCCTCGACCCTCCTCCTGTACATTCCGCAGCTTGTGCAGGCGCTGCGGCACGACACGATGGGATACGTGGCGGAATTGATAAAATCACTGGCGAAGAAATCACAAGTCGTAGCGCACCAGCTGATATGGAACATGCACACGAACATGTACACAGACGAGGAGATGCATAATAAAGATCCGGCCCTATTCGACATCCTCGAGTCGTTGACGAAGAGCATAGTGGATTCCCTGTCGGGACCCGCGAAGGCGTTCTACGAAAGGGAATTCGATTTCTTCGGTCAGATCACGAACATCAGCGGAATCATCAGACCGTACCCCAAGGGAGCGGAGAGGAAGCGAGCCTGCTTGGAAGCGCTGAAGAACGTTAAGGTGCAGCCGGGGTGCTATCTACCCTCCAATCCGGACTCTATGGTCATCGATATAGACTATAAAAGCGGTACTCCCATGCAGAGCGCCGCGAAGGCTCCGTACTTAGCGCGGTTCAGAGTCCGAAAGTACGGGATCGCGGAGATGGAGTCCCTCGCCATGGCCATCGCGTCGGGCGAGGAGCCGCCTGCGGAGGAAGGCAAGGACCGGTACACGTCGATAGCGGCGGAGACCTGGCAGGCGGCCATATTTAAAGTGGGCGATGACGTCAGACAAGACATGCTGGCCCTGCAAGTGATATCGCTGTTCAAGAACATATTCCAGCAAGTCGGCCTGGACTTGTACCTGTTTCCGTACAAAGTCGTCGCCACCGCGCCCGGGAGCGGCGTTATAGAATGCGTGCCCAACGCCAAGTCGCGTGATCAGCTGGGCAGGCAGACGGACTTCGGACTCTACGAATATTTTATAAAGAAATACGGCGACGAGACCACGAGAGAGTTTCAGGCGGCGAGAAGGTGCTTCGTGACCTCGATGGCCGCGTACAGCGTCATCGGCTTCCTGCTGCAGATCAAGGATCGGCACAACGGGAACATCATGCTGGACACGGACGGACACATCATACACATAGATTTCGGATTCATGTTCGAGTCATCGCCCGGCGGGAACCTTGGCTTCGAGCCCGACATCAAGCTGACCGACGAGATGGTGATGGTGATGGGCGGCAAGATGGAGGCGCCGCCGTTCCGCTGGTTCTGTGAACTGTGCGTGCAGGCCTTCTTGGCTGTCAGACCATACCAAGAAGCTATAATATCTATGGTGTCGCTGATGCTGGACACCGGTCTCCCGTGCTTCCGAGGGCAGACGATACGTCACCTTCGCTCGCGTTTCGCGCCCAACTCTACCGAGAAGGAGGCGGCGGCGTACATGCTCTCTATCATACGTAACTCGTTCTTGAACTTTAGAACAAGGACGTACGATATAATACAGTATTACCAGAACCAGATACCGTATTGA

Protein

MYNHWHPSQSLYHYTRKNTVIGTKEITGSKLEPRPPFVAPHAVWVRYLCEVAETAKYNSQEKVEMLASLLHRSLPITVGDYRDHINRHVEAVGVRFKLLSCGLSLLQGDILPRSLARNILRERVYSACLDYFCRGIQCPSKSSGALREDIISLIKFWQLMHSDKKYLKSSDIGGEYELMGPSSQQSLYTSNSPTDNRSSVNSSDIGSRQTTGWINTVPMSTTTLSSGAGSIAGKRSNRSVKPPVKQQDTYVKDYVRKRNLILELMAVEIEFLVTWHNPHGRPEQAVPGEDNIATWRSKPNTERTWRDHAKLAWEISPVLAVFMPERLKNDGIVAEVRRKVQAQPTAVCHVPQALKYLVTTETLLNDAQELVHMITWARVSPVEALSYFSRQYPPHPLSAQAAVNTLTSYPSSTLLLYIPQLVQALRHDTMGYVAELIKSLAKKSQVVAHQLIWNMHTNMYTDEEMHNKDPALFDILESLTKSIVDSLSGPAKAFYEREFDFFGQITNISGIIRPYPKGAERKRACLEALKNVKVQPGCYLPSNPDSMVIDIDYKSGTPMQSAAKAPYLARFRVRKYGIAEMESLAMAIASGEEPPAEEGKDRYTSIAAETWQAAIFKVGDDVRQDMLALQVISLFKNIFQQVGLDLYLFPYKVVATAPGSGVIECVPNAKSRDQLGRQTDFGLYEYFIKKYGDETTREFQAARRCFVTSMAAYSVIGFLLQIKDRHNGNIMLDTDGHIIHIDFGFMFESSPGGNLGFEPDIKLTDEMVMVMGGKMEAPPFRWFCELCVQAFLAVRPYQEAIISMVSLMLDTGLPCFRGQTIRHLRSRFAPNSTEKEAAAYMLSIIRNSFLNFRTRTYDIIQYYQNQIPY

Similarity

Belongs to the PI3/PI4-kinase family.
Belongs to the peptidase C2 family.

Uniprot

A0A212FME8   H9JTG8   A0A3S2TCX0   A0A067QIG5   E0W3P8   A0A069DZT9   + More
A0A023F555   A0A1B6HW70   A0A1B6LF78   A0A0T6BCD2   D2A3W3   A0A2A4JVW0   A0A0A9ZGW4   A0A0A9ZFG5   A0A2H8TZ06   A0A2S2Q5K8   J9JMX5   A0A2J7QZA3   A0A1Y1M0R4   A0A0C9QK07   E2AJ31   A0A0J7L641   U4U5D1   A0A088A932   A0A2A3EB47   A0A195AUW7   E2B3H5   A0A158NNB0   A0A195FY16   A0A195CS11   A0A151IT87   A0A026WVJ6   A0A3L8DIY4   A0A1Q3G3S1   A0A182NV87   B0W0P5   A0A182QGM5   A0A182P1W5   A0A182TSY5   Q7Q237   A0A182RUL6   A0A182I5Q9   W4VRQ0   A0A182JI18   A0A182W9I8   A0A182JW38   A0A1S4EV63   Q17PY3   A0A182GH84   A0A182YIY1   A0A084W1F9   A0A1S4EV62   A0A182MWN4   A0A2M4A7Q3   A0A2M4B8D4   A0A2M4B873   T1J2J9   A0A2M4A6S0   A0A182FVH4   A0A2M4B8D6   W5JJV1   B7QKB8   A0A131XVJ2   V5IIQ8   A0A293MAF0   A0A182X0H0   A0A1I8Q522   A0A1I8Q510   A0A2P6KWY6   V5GI35   A0A0A1X897   A0A0A1WMM2   A0A293LPG1   A0A1A9ULE3   A0A232ER76   A0A1A9XE14   A0A1B0BVY8   A0A1A9W400   A0A1B0AC15   W8BMJ7   A0A1B0FEG5   L7LVG2   A0A131YYL1   K7J6G1   A0A0K8WFR5   A0A0K8TYY2   A0A1E1XB13   A0A0L0BYP1   W8C6T2   A0A034V5U8   A0A1I8M8W2   A0A131XIY6   A0A0M4ETM9   A0A224Z5V5   B4NCK6   B4L8F2   A0A1E1XQJ6   A0A0Q9XGA2   A0A0R3P3H5   A0A1J1I3I5  

Pubmed

22118469    19121390    24845553    20566863    26334808    25474469    + More
18362917    19820115    25401762    28004739    20798317    23537049    21347285    24508170    30249741    12364791    14747013    17210077    17510324    26483478    25244985    24438588    20920257    23761445    25765539    25830018    28648823    24495485    25576852    26830274    20075255    28503490    26108605    25348373    25315136    28049606    28797301    17994087    29209593    15632085   

EMBL

AGBW02007651    OWR54925.1    BABH01003858    BABH01003859    BABH01003860    RSAL01000342    + More
RVE42389.1    KK853329    KDR08422.1    DS235882    EEB20254.1    GBGD01000060    JAC88829.1    GBBI01002518    JAC16194.1    GECU01028793    GECU01025296    GECU01016951    JAS78913.1    JAS82410.1    JAS90755.1    GEBQ01017648    JAT22329.1    LJIG01001952    KRT84988.1    KQ971348    EFA04876.1    NWSH01000564    PCG75623.1    GBHO01002289    GBHO01000336    JAG41315.1    JAG43268.1    GBHO01000337    GBHO01000335    JAG43267.1    JAG43269.1    GFXV01007324    MBW19129.1    GGMS01003842    MBY73045.1    ABLF02021159    ABLF02066729    NEVH01009070    PNF33920.1    GEZM01043027    JAV79373.1    GBYB01003874    JAG73641.1    GL439932    EFN66563.1    LBMM01000586    KMQ98023.1    KB632145    ERL89099.1    KZ288318    PBC28281.1    KQ976738    KYM75852.1    GL445346    EFN89727.1    ADTU01021199    ADTU01021200    KQ981208    KYN44729.1    KQ977372    KYN03282.1    KQ981037    KYN10162.1    KK107109    EZA59099.1    QOIP01000008    RLU19889.1    GFDL01000604    JAV34441.1    DS231818    EDS41347.1    AXCN02001805    AAAB01008979    EAA13769.4    APCN01003485    GANO01000560    JAB59311.1    CH477188    EAT48811.1    JXUM01001263    JXUM01001264    KQ560119    KXJ84380.1    ATLV01019337    KE525268    KFB44053.1    AXCM01006588    GGFK01003502    MBW36823.1    GGFJ01000109    MBW49250.1    GGFJ01000108    MBW49249.1    JH431806    GGFK01003134    MBW36455.1    GGFJ01000110    MBW49251.1    ADMH02001311    ETN63054.1    ABJB010908985    DS958725    EEC19290.1    GEFM01006110    JAP69686.1    GANP01002762    JAB81706.1    GFWV01013093    MAA37822.1    MWRG01004097    PRD30826.1    GANP01014563    JAB69905.1    GBXI01007327    JAD06965.1    GBXI01014386    JAC99905.1    GFWV01005852    MAA30582.1    NNAY01002664    OXU20832.1    JXJN01021533    JXJN01021534    GAMC01008352    GAMC01008349    JAB98203.1    CCAG010016028    GACK01009462    JAA55572.1    GEDV01004284    JAP84273.1    GDHF01002387    JAI49927.1    GDHF01032642    JAI19672.1    GFAC01002912    JAT96276.1    JRES01001143    KNC25163.1    GAMC01008354    GAMC01008351    JAB98204.1    GAKP01021073    JAC37879.1    GEFH01002084    JAP66497.1    CP012528    ALC49915.1    GFPF01010546    MAA21692.1    CH964239    EDW82565.1    CH933815    EDW07927.1    GFAA01002135    JAU01300.1    KRG07526.1    CH379063    KRT06173.1    CVRI01000040    CRK94872.1   

Proteomes

UP000007151    UP000005204    UP000283053    UP000027135    UP000009046    UP000007266    + More
UP000218220    UP000007819    UP000235965    UP000000311    UP000036403    UP000030742    UP000005203    UP000242457    UP000078540    UP000008237    UP000005205    UP000078541    UP000078542    UP000078492    UP000053097    UP000279307    UP000075884    UP000002320    UP000075886    UP000075885    UP000075902    UP000007062    UP000075900    UP000075840    UP000075880    UP000075920    UP000075881    UP000008820    UP000069940    UP000249989    UP000076408    UP000030765    UP000075883    UP000069272    UP000000673    UP000001555    UP000076407    UP000095300    UP000078200    UP000215335    UP000092443    UP000092460    UP000091820    UP000092445    UP000092444    UP000002358    UP000037069    UP000095301    UP000092553    UP000007798    UP000009192    UP000001819    UP000183832   

PRIDE

H9JTG8   

Pfam

PF00454   PI3_PI4_kinase        + More
PF00613   PI3Ka
PF00265   TK
PF01067   Calpain_III
PF00648   Peptidase_C2
PF04212   MIT

Interpro

IPR015433   PI_Kinase        + More
IPR016024   ARM-type_fold       
IPR001263   PI3K_accessory_dom       
IPR036940   PI3/4_kinase_cat_sf       
IPR011009   Kinase-like_dom_sf       
IPR000403   PI3/4_kinase_cat_dom       
IPR018936   PI3/4_kinase_CS       
IPR042236   PI3K_accessory_sf       
IPR001267   Thymidine_kinase       
IPR027417   P-loop_NTPase       
IPR020633   Thymidine_kinase_CS       
IPR007330   MIT       
IPR022684   Calpain_cysteine_protease       
IPR038765   Papain-like_cys_pep_sf       
IPR022683   Calpain_III       
IPR001300   Peptidase_C2_calpain_cat       
IPR036181   MIT_dom_sf       
IPR022682   Calpain_domain_III       
IPR036213   Calpain_III_sf       

SUPFAM

SSF56112   SSF56112        + More
SSF48371   SSF48371       
SSF52540   SSF52540       
SSF49758   SSF49758       
SSF116846   SSF116846       
SSF54001   SSF54001       

Gene 3D

1.10.1070.11     1.25.40.70    

CDD

cd00044  CysPc

ProteinModelPortal

A0A212FME8   H9JTG8   A0A3S2TCX0   A0A067QIG5   E0W3P8   A0A069DZT9   + More
A0A023F555   A0A1B6HW70   A0A1B6LF78   A0A0T6BCD2   D2A3W3   A0A2A4JVW0   A0A0A9ZGW4   A0A0A9ZFG5   A0A2H8TZ06   A0A2S2Q5K8   J9JMX5   A0A2J7QZA3   A0A1Y1M0R4   A0A0C9QK07   E2AJ31   A0A0J7L641   U4U5D1   A0A088A932   A0A2A3EB47   A0A195AUW7   E2B3H5   A0A158NNB0   A0A195FY16   A0A195CS11   A0A151IT87   A0A026WVJ6   A0A3L8DIY4   A0A1Q3G3S1   A0A182NV87   B0W0P5   A0A182QGM5   A0A182P1W5   A0A182TSY5   Q7Q237   A0A182RUL6   A0A182I5Q9   W4VRQ0   A0A182JI18   A0A182W9I8   A0A182JW38   A0A1S4EV63   Q17PY3   A0A182GH84   A0A182YIY1   A0A084W1F9   A0A1S4EV62   A0A182MWN4   A0A2M4A7Q3   A0A2M4B8D4   A0A2M4B873   T1J2J9   A0A2M4A6S0   A0A182FVH4   A0A2M4B8D6   W5JJV1   B7QKB8   A0A131XVJ2   V5IIQ8   A0A293MAF0   A0A182X0H0   A0A1I8Q522   A0A1I8Q510   A0A2P6KWY6   V5GI35   A0A0A1X897   A0A0A1WMM2   A0A293LPG1   A0A1A9ULE3   A0A232ER76   A0A1A9XE14   A0A1B0BVY8   A0A1A9W400   A0A1B0AC15   W8BMJ7   A0A1B0FEG5   L7LVG2   A0A131YYL1   K7J6G1   A0A0K8WFR5   A0A0K8TYY2   A0A1E1XB13   A0A0L0BYP1   W8C6T2   A0A034V5U8   A0A1I8M8W2   A0A131XIY6   A0A0M4ETM9   A0A224Z5V5   B4NCK6   B4L8F2   A0A1E1XQJ6   A0A0Q9XGA2   A0A0R3P3H5   A0A1J1I3I5  

PDB

6BQ1     E-value=0,     Score=2478

KEGG

101741396    K00888 phosphatidylinositol 4-kinase A [EC:2.7.1.67] | (RefSeq) phosphatidylinositol 4-kinase alpha

PATHWAY

00562    Inositol phosphate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04070    Phosphatidylinositol signaling system - Bombyx mori (domestic silkworm)

GO

GO:0046854   GO:0016301   GO:0048015   GO:0004430   GO:0016020   GO:0005886   GO:0005737   GO:0016021   GO:0005524   GO:0004797   GO:0071711   GO:0030010   GO:0007293   GO:0007009   GO:0008582   GO:0007015   GO:0004198   GO:0005488   GO:0006096   GO:0050113   GO:0016740   GO:0006108   GO:0030060   GO:0016615   GO:0000049   GO:0016876  

PANTHER

PTHR10048  

Length:

869

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.4342

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00221

outside

1  -  869

 

 

Pi

154.091784

Theta

160.935761

Tajima's D

0.627721

CLR

0.079978

CSRT

0.549622518874056

Interpretation

Uncertain