Gene

KWMTBOMO09556

Pre Gene Modal

BGIBMGA012828

Annotation

PREDICTED:_phosphatidylinositol_4-kinase_alpha_[Bombyx_mori]

Location

Bomo_Chr16(+):4122286-4147890      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 1.387 PlasmaMembrane   Reliability : 1.12

CDS

ATGGACGAACACGAGTTTTTCACTCAAACTGTGCAACATTTAGCTCGCTGTTTGTCAAGTATAAATCCAACACCATGGGAAAAAGTAAATACTCTGTTTATGCTGTGCCCACAAGCCAGTTCATCCCTGGTTGTAACATCAAAGAGCCAAGAAGCATCCATAGCATTAGGATTGTACTTCCTACAGAGTGGCCTGCAGCACCAGGACAAACTCCTACCATACTTCTTGAAGGTTCTGAAAAGTCTAACAAATGCACAATTTGAGGAGCCACTGTACAGGACCAAAAATAAAGACCGTATACCGATGTCCGAAAAATTCAGCTTCTGTCTAAATACTCTGTTATCCGACGTGGCATCGAAACAGTCGTCTCTACGCGAAGAAATCCTAACAGCGCAAATTGATCTTATGTCGAATCTTACAAAGACCATAATCGATTGCTACGAAAGTCGCGACTTCGATACAGTATCAAAACTTCAGCTGTGCAAGAGCACGGTTCCCGTTCTCATCGGTCTGGCTAGATCCATGGGCAGGTATTCGACGGTCGATCCTCCGTTGCTTTGCCGATTGTTCCCGCAGCCCCCCAGTCCTGTGAAAACAAAGGAACCGGAGCCTAATTTCGAATACGCTACCTTAGATAAGAAGAGAAAATTCAATCAATTCCGCCCCATTATACCTAGGTCTCTGTCTGGGAATTTGCACCTCAATAGCGACAGTATAGTGGAGAATGGCAGCGACACAATGGACAGTGGAGTCGGAACGCTAAAACGCGGCTCCCTTCACAGCTATAACTCGGTCCCCTACGACCCGACCACATATTTCTTCCACAAGTTCGGGTCTAGTTTTAACCAGTTTCCTTACATGAGATTTTCGGAGTCTCCCGAAAAAAGGAACAGTGTCCAATTTTATGTGACGTATCTGCAGTCTATATTGTCGCTGGCAAAAAAGCTGCTCACCAAAGACCTCTTGTCGTTCATCGACGAAGAGGCTGAAGATGTACACGCGTCGGGACAGATAAATGTGTTCCCTTATAAGTCATTCTCGGAAACATTGAATTTGGTAATGGTAACATTATTGAGGGAGTTATTGCAACACCAGAAGGACCTTCCAGGCCCGTTTACCAAAGACGTACAGGAATTCGTAAAATGTCTGTTCCTAAGCGGCCAGACTGAGTTGCAAAGTCGACACCACGACGCTTCCGAGAGAGAAGACAGGGAGAGTAACTACGCCACAGTAAACAAGTTCAAAGTCAACGTGATGGCGAATTCAGCTTGCGTAGATCTTCTGGTTTGGGCCATCGGAGATGAGACAGGAGCCGATTCACTCTGCGGCCGTTTGACAGAGAAAATCAATTCGAATCACAATCACAAATTGATATTAGCTCACATGCCTCTACTGATGGTCTGTCTTGAAGGTCTGGGGAAGTTGGCAACGAAATTCCCGACGATAGCGAACACCTCGATATACTGCCTAAGGGATTTCCTGGTCACACCCTCGCCGATACTGTTCAAGTTGCACAAACTCGAACTCGAGAAAACCGGGAAAGAGCACATGAAAGTCACCCTTCAGGGCAAAGAGCTGCAGGGTCTAACGGAGTCTGGGGTCCCGGTCAAGTCGACGCCGTTCGAGAAGCTTCGGGACGCGGCCATCGAGAACCTGTGCGTGGCGCTGGAGGCGGCGCTCACCGTGGACCCGTACTGCGTGCCCGCGCTGGTGGGCTCCGTCAGCAACAGGCTGTTCACCGCGGAGACCAGCGACAGTGAATCGTCGTTGATAAGCACCAACATAGTGATAATGTTGGGGCACGTGGCGGTCGCGTTAAAGGACACGCCCAAAACGAGTGACACAATACTTCAATTCTTTCAACAGAGATTATGCCGTGCCCCGTCATCGTTGGACACTCTCATCGTGGATCAGTTGGGCTGCATGGCCCTAGCTAGCCCCGAGGGTCCAGCACACGACGAGATCATGAGGATGTTCACTGTCATTACAGTGGAAGCTGCCAGTGCGGTATACCATCACACCGACGACAGGAAACAATACAGGCACGTGTCGGGCGCGGTGCTGAACGCGCTCGCGAACATAGCGGCGAACGTTCGCGGCACGAACGTCCGGCTGGAGCTGCTGACGCGGCTGCTGGAGCTGTTCGTGCAGCTCGGGCTGGGCGGGGAGCGCGCCACGGACCGCTCGCCCGCGCCCGTGCTCAAGGCGTCCGGCAGCGCGGGCAACCTCGGCGTGCTCATACCCGTCATAGCGGTTCTAGTGAAGAGACTCCCACCGATCAAGAACCCGAAACCGAGATTGCACAAGCTGTTCAAAGACTTCTGGCTGTACTGCGTCGTGATGGGATTCACTGCGGCGGAATCAGGTCTATGGCCGCAGGAGTGGTACACGGGCGTGAAAGAGATAGCCGTCAAATCACCTTACCTTGTCTCGCAGACGTCGTTACGTTCGGAAATGCGGGAGTTGCAGTACACTTCGGCGGTAAGGAACGACTCGGTGTCGATAAACGAACTACAAGAACTGAAGACTCAGATATTGAACTTGCTGGAGCACGCGGCCGACATAACGGTCATAGTGAATAAGCTGAGTTTCGCGCCCTGCATGTACATATTGAGCGTCTATTGGCTGGAAACATTGAGGGTGTGCAATTCACCGGAGCCCAGCTTACAACCGATCATAGAATATTTAAGTGATACAACTTTACAAAAGGATAAGGCCGGCATGTGGCAGTGCGTAGCGAGCGTCGGCGACAAGGTGTTCCAGAAGTTTCTCGACGTGATGTCGCAGAAGGTGAAGGACGACTCTCGCGAGCGCGAGCTGGAGGGCCACGCCCAGTTCCTGCTGGTCAACTTCAACCACATCCACAAGCAGATCCGGCGCGTCGCAGACCAGTGGCTCGCCAGGCTCGTCGACAGATTCCCGCATCTGTTGTGGAACTGTCGGGTGCTTTGGTCCATGCTGGATATATTGCAAGTGCTGAGTTTCAGTCTCGAGTTGGACGCGAACCAGGAAACGCCGCTGCTTAAAGTTCCCGGGACAGATTTCACTTTGCAGCTCCAAGACACGTTGGAAGGGAGAGAGAGCATAGTCAAAGACTTCGCCGACCGTTGTCACGGCATCGTCCAGGAAGCCATGAAGTGGGCCCCGCAGTCCACCCGCTCACACCTGCAGGAGTACCTCAACCAGGTCCCGAACTCGACGCTGTGGCACCACTGCGGGCTCGCGCTGGCGACGGGCGCGCTGCTCGGAGCCGCCGGCCTCAACAGGATGTCCGCGCCCCTGCCCCGCGCCGCCCTCGACAAGCGCCCGCCCTGCGTCACGCAGGACTCGGCCGCCTTGCTCGCCGTCGTGTCGCAGAGGAGTCGTTTTGCTGGGGAGGTGCGGTACTGGATCAGATAG

Protein

MDEHEFFTQTVQHLARCLSSINPTPWEKVNTLFMLCPQASSSLVVTSKSQEASIALGLYFLQSGLQHQDKLLPYFLKVLKSLTNAQFEEPLYRTKNKDRIPMSEKFSFCLNTLLSDVASKQSSLREEILTAQIDLMSNLTKTIIDCYESRDFDTVSKLQLCKSTVPVLIGLARSMGRYSTVDPPLLCRLFPQPPSPVKTKEPEPNFEYATLDKKRKFNQFRPIIPRSLSGNLHLNSDSIVENGSDTMDSGVGTLKRGSLHSYNSVPYDPTTYFFHKFGSSFNQFPYMRFSESPEKRNSVQFYVTYLQSILSLAKKLLTKDLLSFIDEEAEDVHASGQINVFPYKSFSETLNLVMVTLLRELLQHQKDLPGPFTKDVQEFVKCLFLSGQTELQSRHHDASEREDRESNYATVNKFKVNVMANSACVDLLVWAIGDETGADSLCGRLTEKINSNHNHKLILAHMPLLMVCLEGLGKLATKFPTIANTSIYCLRDFLVTPSPILFKLHKLELEKTGKEHMKVTLQGKELQGLTESGVPVKSTPFEKLRDAAIENLCVALEAALTVDPYCVPALVGSVSNRLFTAETSDSESSLISTNIVIMLGHVAVALKDTPKTSDTILQFFQQRLCRAPSSLDTLIVDQLGCMALASPEGPAHDEIMRMFTVITVEAASAVYHHTDDRKQYRHVSGAVLNALANIAANVRGTNVRLELLTRLLELFVQLGLGGERATDRSPAPVLKASGSAGNLGVLIPVIAVLVKRLPPIKNPKPRLHKLFKDFWLYCVVMGFTAAESGLWPQEWYTGVKEIAVKSPYLVSQTSLRSEMRELQYTSAVRNDSVSINELQELKTQILNLLEHAADITVIVNKLSFAPCMYILSVYWLETLRVCNSPEPSLQPIIEYLSDTTLQKDKAGMWQCVASVGDKVFQKFLDVMSQKVKDDSRERELEGHAQFLLVNFNHIHKQIRRVADQWLARLVDRFPHLLWNCRVLWSMLDILQVLSFSLELDANQETPLLKVPGTDFTLQLQDTLEGRESIVKDFADRCHGIVQEAMKWAPQSTRSHLQEYLNQVPNSTLWHHCGLALATGALLGAAGLNRMSAPLPRAALDKRPPCVTQDSAALLAVVSQRSRFAGEVRYWIR

Similarity

Belongs to the PI3/PI4-kinase family.

Uniprot

A0A2A4JVW0   A0A194Q0B7   A0A3S2TCX0   A0A194R703   H9JTG6   A0A2H1WD62   + More
A0A212FME8   A0A2J7QZB1   A0A1B6HW70   A0A0J7L641   E2B3H5   D2A3W3   E9IUF9   E0W3P8   A0A2A3EB47   A0A3L8DIY4   A0A151XAH9   A0A158NNB0   A0A088A932   A0A195AUW7   F4WLH5   A0A195CS11   A0A195FY16   N6UPZ7   A0A1Y1M0R4   A0A151IT87   A0A0T6BCD2   A0A1B6F982   A0A232ER76   A0A154P7H1   A0A023F555   K7J6G1   A0A2S2Q5K8   A0A2H8TZ06   T1J2J9   Q17PY3   A0A182GH84   A0A182W9I8   A0A1S4EV62   A0A182NV87   A0A182QGM5   A0A1Q3G3S1   A0A182P1W5   A0A182JW38   A0A182JI18   A0A182RUL6   Q7Q237   A0A084W1F9   A0A182TSY5   A0A2M4A6S0   A0A2M4B8D4   A0A2M4B873   A0A2M4B8D6   A0A182FVH4   A0A182MWN4   A0A1S4EV63   A0A182YIY1   A0A182I5Q9   A0A026WVJ6   W4VRQ0   A0A182X0H0   W5JJV1   A0A0K8WAE9   W8BMJ7   A0A0K8WA29   A0A0K8TYY2   A0A0A1WMM2   A0A2P6KDP0   B4L8F2   B4JNN6   A0A0K8WFR5   A0A0M4ETM9   A0A0Q9XGA2   A0A0L0BYP1   A0A3B0KDM4   Q29IN8   B3MYZ9   A0A1W4VRL4   Q9W4X4   B3P939   A0A1I8Q522   B4NCK6   B4M219   A0A1I8M8W2   A0A0R3P3H5   A0A0N8NZF3   A0A1W4VQW3   A0A0Q5SRX6   M9PDM4   A0A1I8Q510   B4H2S6   A0A0A9ZJ42   B4Q0Y3   A0A0A9ZGW4   A0A131XIY6   A0A224Z5V5   A0A131YYL1   L7LVG2  

Pubmed

26354079    19121390    22118469    20798317    18362917    19820115    + More
21282665    20566863    30249741    21347285    21719571    23537049    28004739    28648823    25474469    20075255    17510324    26483478    12364791    14747013    17210077    24438588    25244985    24508170    20920257    23761445    24495485    25830018    17994087    26108605    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25315136    25401762    17550304    28049606    28797301    26830274    25576852   

EMBL

NWSH01000564    PCG75623.1    KQ459582    KPI99001.1    RSAL01000342    RVE42389.1    + More
KQ460878    KPJ11646.1    BABH01003868    ODYU01007757    SOQ50802.1    AGBW02007651    OWR54925.1    NEVH01009070    PNF33923.1    GECU01028793    GECU01025296    GECU01016951    JAS78913.1    JAS82410.1    JAS90755.1    LBMM01000586    KMQ98023.1    GL445346    EFN89727.1    KQ971348    EFA04876.1    GL765974    EFZ15805.1    DS235882    EEB20254.1    KZ288318    PBC28281.1    QOIP01000008    RLU19889.1    KQ982351    KYQ57288.1    ADTU01021199    ADTU01021200    KQ976738    KYM75852.1    GL888208    EGI64911.1    KQ977372    KYN03282.1    KQ981208    KYN44729.1    APGK01021733    APGK01021734    APGK01021735    APGK01021736    APGK01021737    APGK01021738    APGK01021739    APGK01021740    APGK01021741    APGK01021742    KB740358    ENN80812.1    GEZM01043027    JAV79373.1    KQ981037    KYN10162.1    LJIG01001952    KRT84988.1    GECZ01022990    JAS46779.1    NNAY01002664    OXU20832.1    KQ434829    KZC07783.1    GBBI01002518    JAC16194.1    GGMS01003842    MBY73045.1    GFXV01007324    MBW19129.1    JH431806    CH477188    EAT48811.1    JXUM01001263    JXUM01001264    KQ560119    KXJ84380.1    AXCN02001805    GFDL01000604    JAV34441.1    AAAB01008979    EAA13769.4    ATLV01019337    KE525268    KFB44053.1    GGFK01003134    MBW36455.1    GGFJ01000109    MBW49250.1    GGFJ01000108    MBW49249.1    GGFJ01000110    MBW49251.1    AXCM01006588    APCN01003485    KK107109    EZA59099.1    GANO01000560    JAB59311.1    ADMH02001311    ETN63054.1    GDHF01004247    JAI48067.1    GAMC01008352    GAMC01008349    JAB98203.1    GDHF01004377    JAI47937.1    GDHF01032642    JAI19672.1    GBXI01014386    JAC99905.1    MWRG01014940    PRD24452.1    CH933815    EDW07927.1    CH916371    EDV92329.1    GDHF01002387    JAI49927.1    CP012528    ALC49915.1    KRG07526.1    JRES01001143    KNC25163.1    OUUW01000011    SPP86370.1    CH379063    EAL32615.1    CH902632    EDV32843.2    AE014298    AAF45800.3    CH954183    EDV45644.1    CH964239    EDW82565.1    CH940651    EDW65723.2    KRT06173.1    KPU74164.1    KQS26044.1    AGB95037.1    CH479204    EDW30643.1    GBHO01000334    JAG43270.1    CM000162    EDX01350.1    GBHO01002289    GBHO01000336    JAG41315.1    JAG43268.1    GEFH01002084    JAP66497.1    GFPF01010546    MAA21692.1    GEDV01004284    JAP84273.1    GACK01009462    JAA55572.1   

Proteomes

UP000218220    UP000053268    UP000283053    UP000053240    UP000005204    UP000007151    + More
UP000235965    UP000036403    UP000008237    UP000007266    UP000009046    UP000242457    UP000279307    UP000075809    UP000005205    UP000005203    UP000078540    UP000007755    UP000078542    UP000078541    UP000019118    UP000078492    UP000215335    UP000076502    UP000002358    UP000008820    UP000069940    UP000249989    UP000075920    UP000075884    UP000075886    UP000075885    UP000075881    UP000075880    UP000075900    UP000007062    UP000030765    UP000075902    UP000069272    UP000075883    UP000076408    UP000075840    UP000053097    UP000076407    UP000000673    UP000009192    UP000001070    UP000092553    UP000037069    UP000268350    UP000001819    UP000007801    UP000192221    UP000000803    UP000008711    UP000095300    UP000007798    UP000008792    UP000095301    UP000008744    UP000002282   

PRIDE

H9JTG6    Q9W4X4    M9PDM4   

Pfam

PF00613   PI3Ka        + More
PF00454   PI3_PI4_kinase
PF00265   TK

Interpro

IPR015433   PI_Kinase        + More
IPR001263   PI3K_accessory_dom       
IPR016024   ARM-type_fold       
IPR011009   Kinase-like_dom_sf       
IPR018936   PI3/4_kinase_CS       
IPR000403   PI3/4_kinase_cat_dom       
IPR042236   PI3K_accessory_sf       
IPR036940   PI3/4_kinase_cat_sf       
IPR001267   Thymidine_kinase       
IPR027417   P-loop_NTPase       
IPR020633   Thymidine_kinase_CS       

SUPFAM

SSF48371   SSF48371        + More
SSF56112   SSF56112       
SSF52540   SSF52540       

Gene 3D

1.25.40.70     1.10.1070.11    

ProteinModelPortal

A0A2A4JVW0   A0A194Q0B7   A0A3S2TCX0   A0A194R703   H9JTG6   A0A2H1WD62   + More
A0A212FME8   A0A2J7QZB1   A0A1B6HW70   A0A0J7L641   E2B3H5   D2A3W3   E9IUF9   E0W3P8   A0A2A3EB47   A0A3L8DIY4   A0A151XAH9   A0A158NNB0   A0A088A932   A0A195AUW7   F4WLH5   A0A195CS11   A0A195FY16   N6UPZ7   A0A1Y1M0R4   A0A151IT87   A0A0T6BCD2   A0A1B6F982   A0A232ER76   A0A154P7H1   A0A023F555   K7J6G1   A0A2S2Q5K8   A0A2H8TZ06   T1J2J9   Q17PY3   A0A182GH84   A0A182W9I8   A0A1S4EV62   A0A182NV87   A0A182QGM5   A0A1Q3G3S1   A0A182P1W5   A0A182JW38   A0A182JI18   A0A182RUL6   Q7Q237   A0A084W1F9   A0A182TSY5   A0A2M4A6S0   A0A2M4B8D4   A0A2M4B873   A0A2M4B8D6   A0A182FVH4   A0A182MWN4   A0A1S4EV63   A0A182YIY1   A0A182I5Q9   A0A026WVJ6   W4VRQ0   A0A182X0H0   W5JJV1   A0A0K8WAE9   W8BMJ7   A0A0K8WA29   A0A0K8TYY2   A0A0A1WMM2   A0A2P6KDP0   B4L8F2   B4JNN6   A0A0K8WFR5   A0A0M4ETM9   A0A0Q9XGA2   A0A0L0BYP1   A0A3B0KDM4   Q29IN8   B3MYZ9   A0A1W4VRL4   Q9W4X4   B3P939   A0A1I8Q522   B4NCK6   B4M219   A0A1I8M8W2   A0A0R3P3H5   A0A0N8NZF3   A0A1W4VQW3   A0A0Q5SRX6   M9PDM4   A0A1I8Q510   B4H2S6   A0A0A9ZJ42   B4Q0Y3   A0A0A9ZGW4   A0A131XIY6   A0A224Z5V5   A0A131YYL1   L7LVG2  

PDB

6BQ1     E-value=8.9196e-59,     Score=579

KEGG

101741396    K00888 phosphatidylinositol 4-kinase A [EC:2.7.1.67] | (RefSeq) phosphatidylinositol 4-kinase alpha

GO

GO:0046854   GO:0048015   GO:0016301   GO:0016020   GO:0005886   GO:0004430   GO:0005737   GO:0016021   GO:0005524   GO:0004797   GO:0071711   GO:0030010   GO:0007293   GO:0007009   GO:0008582   GO:0007015   GO:0048477   GO:0016310   GO:0005488   GO:0004332   GO:0006096   GO:0050113   GO:0016740   GO:0006108   GO:0030060   GO:0016615   GO:0000049   GO:0016876  

PANTHER

PTHR10048  

Length:

1132

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.66717

Exp number, first 60 AAs:

0.00132

Total prob of N-in:

0.00016

outside

1  -  1132

 

 

Pi

215.827119

Theta

162.441903

Tajima's D

1.070291

CLR

0.124804

CSRT

0.67791610419479

Interpretation

Uncertain