Silkworm Genome Informatics Database

Gene

KWMTBOMO09542 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013025

Annotation

PREDICTED:_eukaryotic_translation_initiation_factor_3_subunit_A_isoform_X4_[Papilio_polytes]

Location

Bomo_Chr16(-):3576807-3596290 View in EpiBrowser

Full name

Eukaryotic translation initiation factor 3 subunit A

Alternative Name

Eukaryotic translation initiation factor 3 subunit 10

Location in the cell

Cytoplasmic Reliability : 1.744 Nuclear Reliability : 1.938

CDS

ATGGCGCGATACGGTCAAAGACCGGAAAATGCCCTTAAACGGGCCAATGAGTTCATGGATTTGGACAAACCAGCAAGGGCCCTAGACACCTTACAGGAAGTTTTCCGTAACAAAAAATGGGCCTACAACTGGTCCGAATCTGTCCTAGAACCAATCATGTTCAAATACTTGGAACTTTGCGTTGATCTACGTAAATCTCATGTTGCAAAGGAAGGTCTGTTCCAGTACAGAAACATGTTCCAATCAGTTAACGTTGGGTCTTTGGAGCAGGTTATAAGAGGCTATCTCCGTATGGCAGAGGAACGCACAGAAACAGCCAGGGCTTTATCGACGCAGGCCGTCATAGACACTGATGATCTGGATAACCTTGCAACCCCGGAGAGCATACTCCTGAGTGCAGTGTCAGGTGAAGATGCCCAGGACCGATCTGACAGAACAATACTCACACCATGGGTGAAATTCCTTTGGGAATCCTACTGCCAATGCCTGGAGCTCCTTCGTACGAATGCTCATGTGGAAACCTTGTATCATGATATTGCTCGCATGGCCTTCCAATTTTGTTTAAAGTACTCGCGAAAAACAGAATTCAGAAAGCTTTGTGATAAACTAAGGAAACATCTTGAAGATATTTGCAAACCTACAGTGCAAACTGGTAACGTTAGCATTTCAAAACCAGAAACTCAACAGCTGAACCTCGAAACAAGATTGTTCCAGCTCGACTGTGCAATTCAAATGGAGTTATGGCAGGAAGCCTATAAAGCCATTGAAGACATCCACAACCTAATGAACATGTCTAAAAAAACTCCAGTCGCCAAAACTATGGCCAACTACTATGGGAAACTGGCACTTGTTTTCTGGAAAGCTGGCCACTGCCTATTCCATGCTGCAGCCTTGCTGAAACTCTTCCAGCTATACAGGGAGATGAAGAAGAACATCACCCAAGAGGAACTGCAGAAGATGGCGTGTCAAGTACTGGTAGCGGTGCTGTCTGTGCCACTGCCATCTCTACACCCTGAGCTCGATCGCTTTGTCGAGACGGATAAGAGCCCTGTTGAGAAGGCCCAACGTTTGGCTGTACTGCTCGGTCTTGCTCAACCACCGACCAGGGCAAGTCTTTTGAAAGATATCGTCCGCCTTAACGTCGTGTCGCTGGCATCGCCTCAACTTCAACAGCTTTATTCTTGGCTTGAAGTGGAATTCGACCCTCTGACCATCTGCCTTAATGTCAAGGGTGTTATCAAATCTTTGCAGGATGAGCCAAATTCATCGCTCGCTCAGTACACCAATGCCTTGACGGACGTGGCCCTGGTGAGGCTGATCCGTCAGGTGGCCCAGTGCTACGCGTGCGTGCAGTTCTCCCGGCTGCTGGAGCTGGCGGCCACCGACGACCTGTTCCATCTGGAGCGCTTGCTCGTCGACTGCGTGCGCCACAACGACATGCAGATACGCATCGATCACGCCAACAAGTGCGTGCACTTTGGCGTAGAAGCGGGCGGCGGCGAGTGGTGCTCGGCCGCGGACGAAGCCTGCGGCGGGGCCATCCTGCAAGCCACCCCGGCGGAACAGGTCCGCGAGCAGCTGGTCCGCGCGGCGGAGGTGCTGTCCCGCGTGGTGGGCGCGCTGTACCCGCAGCGGCGCGGCGCCGAGCGGGAGCGCGCCCGCGCCGCCATGGTGCAGTACTACCACGAGAACAAGCAGGCCGAGCACCACCGCGTGCTGCAGCGCCACAAGATCATCGAAGAACGGAAGGAGTACATCGAGCGACTCAACACCGTGCGCGAGGAGGAGGAACTCAGGCGTCAAGAGGAGCAGCTCCGCGCGGCCGCCATCGCCGAGGCCCGCCGCTTGGAGCAGGAGCGTGAGGAGCGCGAGAAGAAGCGCCACGCGTCGGAGCTGGCCGCCATGAGGGAGCGACACCTCAAGGAACGCATGGCGCACATCTCTCAGACCGCGCACGGACAAAAGATGCTCGGAAAACTCAATGAGGAGGATCTTAAGAAAATGGATGCTGAAGCTATTGCTCAGCGGGAAGCTGAAGAACTGATGAAGGAACGTCGCGAGCTTCAGGCTAGACTGAAGTCACAGGAGAAAAAGGTGGATTACTTTGAGCGTGCCAAGCGATTGGAAGAAATACCACTTCTGCAGAAGAGCCTGGAAGAGAAACAGGTTCAAGACAAGGCATTCTGGGAGCAACAGGAAAAAGAACGCATCGAACAACTCATAGAGGCTCGCGCCTTAGACGTGGCCACGTCGGAGCGCATGTCCCGCATGGCGGTCCACCGCGACGAATTCATGGCGCGACTTCGCTCGGAACGTGGGGCCGCCTACGCTCAAAAGGTAGCCGCTTTCAACGAGAAACTTCAAGCCGAGAAGGAAAAGAGATTAGCTGAGAGACGCGCTCAGCGAATCGAGAAGAGAAGACATGAGTGGATAACAGAGAAGCGTCGCGCTGAGGAACGTGCGGCTGAGGAAGCTCGACGCATCAAGGAAGAGGAAGAAAAGAGAGAAAGGGAAGAACGAGAGAGGAAACAGCAAGAAGAAATGGAAGCGTTGAGAGAGAAAAAAGAGAAAGAACACAAAGAGATGTTGGCACGCGCCGAGGCCAAGGCCCGCGCCAAGGAAGCCGAGATACAACGGAAACTGGAGGGACAACGCGCCGCCGTCCCCCCGCCCGCCACCTCCTCCAGCTGGAGACGAGGACAACCTGCCCCTACCGAACGAGACGACGCCTGGAGGGGCAAGGAAGCACCTGATGCTGGGGAAAAGAAGTCCTCTGATCAATGGAGAACCAGTCGTGTCCGTGAACCCGTACGTGACGAGCGAGCTCGCAGTCCGGAACGACGCCGCGAAGATCGTCCACCCCCCAGGGATGAGCGGCCGTCTCTTAGGGACGAGCGTCCGCCTCCCAGGGACGAAAGACCACCGCCCAGGGACGAAAGACCACCGCCCAGGGACGATCGTCCACCACCCAGGGATGATTGGGCTAGGGAAGACAAACGTGAAGAACGTCCACGGGAAGATCGTTCCAGGGAAGACAGACCTGCACCGAGAGATGATGGTGCCTGGAGATCAGCTAACCGAGAACCGGACAGAGACAGACCTCGCTATGGCGGCCGATCCAGTGGACCCGAGACCAGCTGGCGTCGCGGACCTGCCGAGCCACGACCAGCGCCTACCGAACGCTCTGGAACCTGGCGTTCTAAGGACGCACCACCGCGCGACGATCGGTTCAGAGAGAGAGACAGATATCCACCCCGCAGAGATGAACGTGATGGACCTAGGCGTGACGACAGAGACGGTCCCAGACGCGATGATAGAGACGGTCCGAGACGCGATGACAGGGACGCTCCCAGACGCGATGACAGAGATGGTCCCAGACGTGACGATAGGGATGGTCCCAGGCGTGACGATAGGGATGGTCCCAGGCGCGACGACAGAGACGGACCTCGACGTGACGATCGTGATCGTCGCCCTCCGCCCCCTCGTCGCGATGAAAAACCTCGCGATCCTGAAAGCAGCGGTTGGCAAGAAGTGCGGCGTTGA

Protein

MARYGQRPENALKRANEFMDLDKPARALDTLQEVFRNKKWAYNWSESVLEPIMFKYLELCVDLRKSHVAKEGLFQYRNMFQSVNVGSLEQVIRGYLRMAEERTETARALSTQAVIDTDDLDNLATPESILLSAVSGEDAQDRSDRTILTPWVKFLWESYCQCLELLRTNAHVETLYHDIARMAFQFCLKYSRKTEFRKLCDKLRKHLEDICKPTVQTGNVSISKPETQQLNLETRLFQLDCAIQMELWQEAYKAIEDIHNLMNMSKKTPVAKTMANYYGKLALVFWKAGHCLFHAAALLKLFQLYREMKKNITQEELQKMACQVLVAVLSVPLPSLHPELDRFVETDKSPVEKAQRLAVLLGLAQPPTRASLLKDIVRLNVVSLASPQLQQLYSWLEVEFDPLTICLNVKGVIKSLQDEPNSSLAQYTNALTDVALVRLIRQVAQCYACVQFSRLLELAATDDLFHLERLLVDCVRHNDMQIRIDHANKCVHFGVEAGGGEWCSAADEACGGAILQATPAEQVREQLVRAAEVLSRVVGALYPQRRGAERERARAAMVQYYHENKQAEHHRVLQRHKIIEERKEYIERLNTVREEEELRRQEEQLRAAAIAEARRLEQEREEREKKRHASELAAMRERHLKERMAHISQTAHGQKMLGKLNEEDLKKMDAEAIAQREAEELMKERRELQARLKSQEKKVDYFERAKRLEEIPLLQKSLEEKQVQDKAFWEQQEKERIEQLIEARALDVATSERMSRMAVHRDEFMARLRSERGAAYAQKVAAFNEKLQAEKEKRLAERRAQRIEKRRHEWITEKRRAEERAAEEARRIKEEEEKREREERERKQQEEMEALREKKEKEHKEMLARAEAKARAKEAEIQRKLEGQRAAVPPPATSSSWRRGQPAPTERDDAWRGKEAPDAGEKKSSDQWRTSRVREPVRDERARSPERRREDRPPPRDERPSLRDERPPPRDERPPPRDERPPPRDDRPPPRDDWAREDKREERPREDRSREDRPAPRDDGAWRSANREPDRDRPRYGGRSSGPETSWRRGPAEPRPAPTERSGTWRSKDAPPRDDRFRERDRYPPRRDERDGPRRDDRDGPRRDDRDGPRRDDRDAPRRDDRDGPRRDDRDGPRRDDRDGPRRDDRDGPRRDDRDRRPPPPRRDEKPRDPESSGWQEVRR

Description

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

Similarity

Belongs to the eIF-3 subunit A family.

Uniprot

H9JU13 A0A2W1BL64 A0A2A4K3I7 A0A2A4K4I4 A0A3S2TJL8 A0A194Q096 + More
A0A212FMT0 A0A0N0PCC6 S4NSG6 A0A1W4W4T7 A0A1Y1N143 A0A232FFC2 K7IXY7 A0A1J1HJ35

Pubmed

19121390 28756777 26354079 22118469 23622113 28004739 + More
28648823 20075255

EMBL

BABH01003924 KZ150097 PZC73596.1 NWSH01000169 PCG78817.1 PCG78818.1 + More
RSAL01000093 RVE47922.1 KQ459582 KPI98981.1 AGBW02007651 OWR55033.1 KQ460635 KPJ13432.1 GAIX01014107 JAA78453.1 GEZM01015455 JAV91633.1 NNAY01000287 OXU29461.1 CVRI01000006 CRK88039.1

Proteomes

UP000005204 UP000218220 UP000283053 UP000053268 UP000007151 UP000053240 + More
UP000192223 UP000215335 UP000002358 UP000183832

PRIDE

H9JU13

Pfam

PF01399 PCI

Interpro

IPR000717 PCI_dom + More
IPR027512 EIF3A

ProteinModelPortal

H9JU13 A0A2W1BL64 A0A2A4K3I7 A0A2A4K4I4 A0A3S2TJL8 A0A194Q096 + More
A0A212FMT0 A0A0N0PCC6 S4NSG6 A0A1W4W4T7 A0A1Y1N143 A0A232FFC2 K7IXY7 A0A1J1HJ35

PDB

6FEC E-value=8.95824e-175, Score=1580

KEGG

101744517 K03254 translation initiation factor 3 subunit A | (RefSeq) eukaryotic translation initiation factor

PATHWAY

03013 RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0005852 GO:0003743 GO:0001732 GO:0016282 GO:0033290 GO:0005515 GO:0019310 GO:0050113 GO:0016740 GO:0006108 GO:0030060 GO:0016615 GO:0000049 GO:0016876

PANTHER

PTHR14005

Subcellular location

Cytoplasm

Length:

1180

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.53665

Exp number, first 60 AAs:

0.0007

Total prob of N-in:

0.16076

outside

1 - 1180

Pi

23.666168

Theta

195.682935

Tajima's D

-1.46205

CLR

14.50591

CSRT

0.0669966501674916

Interpretation

Uncertain

Source	Sequence	Identity	Evalue
31250652	IGSGSFGDIYLGTAR	100.00	1e-04
28556443	TAGAAADLGAAMYAK	100.00	4e-04
28467696	RGPPPNQGGAQGDEGQEGGIVPSQR	100.00	0.002
26822097	AIEDIHNIMNMSK	100.00	0.016
25044914	QVAENNPYIGIDCMSK	100.00	0.016
26822097	FVETDKSPVEK	100.00	0.025
26280517	AADREIAAEDSIR	100.00	0.025
25044914	AAVPIAIVDR	100.00	0.025
28467696	AAVMEYIAAEVIEIAGNAAR	100.00	0.025

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics