Gene

KWMTBOMO09499

Pre Gene Modal

BGIBMGA013054

Annotation

ischemia/reperfusion_inducible_protein_[Bombyx_mori]

Location

Bomo_Chr16(-):2564417-2565717      View in EpiBrowser

Full name

Threonylcarbamoyl-AMP synthase      

Alternative Name

L-threonylcarbamoyladenylate synthase

Location in the cell

Mitochondrial   Reliability : 3.098

CDS

ATGTGCTCACAACTGGAGAGATTAAACTCATTGCGACTATTAACGAGTATGAAATTACTCAAACTTGGATTGTATCCTAGTTATATACGAAGAAATAAATGTCAATCTTTAATGATGAGAAACACAATGACATCTGTCATATCATGTGTAGATTTCACTGCAAGCTTGAGGGCTGCTGAATGCCTGGCTAAGGGCCAAGTGATTGCTGTACCGACAGACACAATCTATGGATTAGCTTGCAGTGCCAACTGTCCTCTGGCTATCAAAAAACTTTACTCTATAAAAGGAAGAGAGGCAGTGAAACCGGTGGCCATATGTGTCACTAGTGTAGCTGATTTGAGAAAATGGGGAGAAGCCTCTCACATAAGTGACAAGTTATTAGATTCGCTACTTCCTGGTCCAGTCACAGTTGTTCTACAGAAAACTAAACACCTAGACAATCCATTTTTGAATCCTTCCACTACAAAAATAGGTATTAGAATACCGAAGCATGATTTTATGAACACAGTTACGAAAATATTTGATATGCCAGTTGCATTGACAAGTGCCAATTTTAGTAATGAACCTTCAACATTGTCCATCAAAGAATTTGAACATCTGTATCCTCATTTAGCAGCCATATTTGATGGAGGGTTACTGAGTCAAGGTCTGGAACAGAACAGAACAGGCTCCACGGTTATAGATTTATCAAAGAATGGCCTTTATAAAATTATAAGAAAGGGTATATCATATGACAATGTTATAAAAGTTGTTGAACGTTATGGTTTGAAAAAAAATAATGAATCTGAAAATTCATTAGAGATAAATCAACAATTGCAGAAATAA

Protein

MCSQLERLNSLRLLTSMKLLKLGLYPSYIRRNKCQSLMMRNTMTSVISCVDFTASLRAAECLAKGQVIAVPTDTIYGLACSANCPLAIKKLYSIKGREAVKPVAICVTSVADLRKWGEASHISDKLLDSLLPGPVTVVLQKTKHLDNPFLNPSTTKIGIRIPKHDFMNTVTKIFDMPVALTSANFSNEPSTLSIKEFEHLYPHLAAIFDGGLLSQGLEQNRTGSTVIDLSKNGLYKIIRKGISYDNVIKVVERYGLKKNNESENSLEINQQLQK

Description

Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

Catalytic Activity

ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate

Similarity

Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
Belongs to the SUA5 family.

Uniprot

Q2F638   H9JU42   A0A2W1B6N6   A0A2A4JIU2   S4P972   A0A0L7LTN2   + More
A0A194Q0I7   A0A0N1IDT4   A0A212FMX8   A0A023EMJ1   Q17L90   A0A2M4BWL8   A0A182FHI9   A0A0K8TSC5   W5JB92   A0A1Q3F4A0   A0A2M4AGY8   A0A182NI01   A0A2M4AJT7   A0A1J1I108   A0A2M4BWE8   B0X902   A0A1I8MQN2   T1DQE4   A0A0P9ACW7   A0A240PNZ4   A0A182XYR7   A0A2M4AEP0   A0A2M4AEQ1   A0A0R3NMZ9   A0A2M4ADT0   A0A0M4EJI0   A0A3B0IZU4   A0A1W4VHH9   B4MEA0   A0A2M3ZBG6   A0A2M3ZBE5   A0A1I8PQP7   B4MPJ1   B4KR44   B4J957   Q8SYJ9   Q7QJB7   A0A182V5U6   B4GGZ5   B4QF35   B3NJR9   A0A182LUH5   A0A182M6Q1   A0A1S3D309   A0A0A1WEB3   B4PA36   A0A0A1WMP6   A0A182WJC4   B4HQM8   A0A182KR71   A0A182UHI7   A0A1L8DHN9   A0A182PQJ6   A0A1L8DHW3   A0A443S6H7   A0A0K8WBE7   A0A182I364   E0VJY7   T2MAG2   U5D144   A0A1S3J0D6   A0A1Y9H9F2   A0A0D6R320   A0A1B6D014   A0A087SYA8   A0A1X7UH48   A0A2J7PHD8   E9H210   W5UDQ8   A0A287A202   K4AFB7   A0A452DV91   A0A1U7R2K0   W5QF38   A0A067QW52   T1HN26   A0A443RQ77   A0A1A6HTU9   J9K8U0   A4IG71   K4ADP5   A0A293M8X2   A0A0A0LUP4   A0A3B1JK95   F1R994   A0A1Y1JX87   A0A2Y9DCQ3   A0A0D9VQV4   A0A3B1IRF6   G1SNT6  

EC Number

2.7.7.87

Pubmed

19121390    28756777    23622113    26227816    26354079    22118469    + More
24945155    17510324    26369729    20920257    23761445    25315136    17994087    25244985    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    12364791    14747013    17210077    22936249    25830018    17550304    20966253    20566863    24065732    24357323    21292972    23127152    30723633    22580951    20809919    24845553    23594743    19881527    19495411    20565788    22047402    25329095    28004739    21993624   

EMBL

DQ311234    ABD36179.1    BABH01004030    KZ150346    PZC71278.1    NWSH01001411    + More
PCG71330.1    GAIX01003859    JAA88701.1    JTDY01000111    KOB78797.1    KQ459582    KPI99066.1    KQ460651    KPJ13013.1    AGBW02007651    OWR55059.1    GAPW01003548    JAC10050.1    CH477217    EAT47485.1    GGFJ01008326    MBW57467.1    GDAI01000562    JAI17041.1    ADMH02001732    ETN61266.1    GFDL01012653    JAV22392.1    GGFK01006661    MBW39982.1    GGFK01007728    MBW41049.1    CVRI01000038    CRK94031.1    GGFJ01008222    MBW57363.1    DS232513    EDS42908.1    GAMD01001205    JAB00386.1    CH902619    KPU75915.1    GGFK01005923    MBW39244.1    GGFK01005929    MBW39250.1    CM000071    KRT02382.1    GGFK01005624    MBW38945.1    CP012524    ALC41417.1    OUUW01000001    SPP73825.1    CH940662    EDW58865.1    GGFM01005074    MBW25825.1    GGFM01005070    MBW25821.1    CH963849    EDW74030.1    CH933808    EDW08231.1    CH916367    EDW02432.1    AE013599    AY071501    AAF57437.2    AAL49123.1    AAAB01008807    EAA04653.3    CH479183    EDW35765.1    CM000362    CM002911    EDX07946.1    KMY95309.1    CH954179    EDV55338.1    AXCM01001984    AXCM01005915    GBXI01016963    JAC97328.1    CM000158    EDW91367.1    GBXI01014594    JAC99697.1    CH480816    EDW48731.1    GFDF01008118    JAV05966.1    GFDF01008117    JAV05967.1    NCKV01007048    RWS23137.1    GDHF01003917    JAI48397.1    APCN01000199    DS235235    EEB13693.1    HAAD01002857    CDG69089.1    KI392493    ERN15970.1    AXCN02000386    GCKF01027303    GCKF01027302    JAG98227.1    GEDC01018304    JAS18994.1    KK112514    KFM57847.1    NEVH01025141    PNF15742.1    GL732584    EFX74263.1    JT413219    AHH40161.1    AEMK02000045    DQIR01198614    HDB54091.1    AGNK02006093    LWLT01000004    AMGL01000860    AMGL01000861    KK852888    KDR14324.1    ACPB03015125    NCKU01000077    RWS17415.1    LZPO01010358    OBS81676.1    ABLF02033536    CU855952    FQ323133    BC134955    AAI34956.1    CM003536    RCV46048.1    GFWV01012505    MAA37234.1    CM002922    KGN64719.1    GEZM01102065    GEZM01102061    JAV51995.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053268    UP000053240    UP000007151    + More
UP000008820    UP000069272    UP000000673    UP000075884    UP000183832    UP000002320    UP000095301    UP000007801    UP000075880    UP000076408    UP000001819    UP000092553    UP000268350    UP000192221    UP000008792    UP000095300    UP000007798    UP000009192    UP000001070    UP000000803    UP000007062    UP000075903    UP000008744    UP000000304    UP000008711    UP000075883    UP000079169    UP000002282    UP000075920    UP000001292    UP000075882    UP000075902    UP000075885    UP000288716    UP000075840    UP000009046    UP000017836    UP000085678    UP000075886    UP000054359    UP000007879    UP000235965    UP000000305    UP000221080    UP000008227    UP000291000    UP000189706    UP000002356    UP000027135    UP000015103    UP000285301    UP000092124    UP000007819    UP000000437    UP000004995    UP000029981    UP000018467    UP000248480    UP000032180    UP000001811   

PRIDE

Q2F638    H9JU42    Q8SYJ9   

Pfam

PF01300   Sua5_yciO_yrdC        + More
PF02150   RNA_POL_M_15KD
PF01096   TFIIS_C
PF00717   Peptidase_S24

Interpro

IPR017945   DHBP_synth_RibB-like_a/b_dom        + More
IPR006070   YrdC-like_dom       
IPR001529   DNA-dir_RNA_pol_M/15kDasu       
IPR001222   Znf_TFIIS       
IPR019761   DNA-dir_RNA_pol-M_15_CS       
IPR034014   Zn_ribbon_RPC11_C       
IPR036286   LexA/Signal_pep-like_sf       
IPR000223   Pept_S26A_signal_pept_1       
IPR015927   Peptidase_S24_S26A/B/C       
IPR010923   t(6)A37_SUA5       

SUPFAM

SSF55821   SSF55821        + More
SSF51306   SSF51306       

CDD

cd10509  Zn-ribbon_RPC11

ProteinModelPortal

Q2F638   H9JU42   A0A2W1B6N6   A0A2A4JIU2   S4P972   A0A0L7LTN2   + More
A0A194Q0I7   A0A0N1IDT4   A0A212FMX8   A0A023EMJ1   Q17L90   A0A2M4BWL8   A0A182FHI9   A0A0K8TSC5   W5JB92   A0A1Q3F4A0   A0A2M4AGY8   A0A182NI01   A0A2M4AJT7   A0A1J1I108   A0A2M4BWE8   B0X902   A0A1I8MQN2   T1DQE4   A0A0P9ACW7   A0A240PNZ4   A0A182XYR7   A0A2M4AEP0   A0A2M4AEQ1   A0A0R3NMZ9   A0A2M4ADT0   A0A0M4EJI0   A0A3B0IZU4   A0A1W4VHH9   B4MEA0   A0A2M3ZBG6   A0A2M3ZBE5   A0A1I8PQP7   B4MPJ1   B4KR44   B4J957   Q8SYJ9   Q7QJB7   A0A182V5U6   B4GGZ5   B4QF35   B3NJR9   A0A182LUH5   A0A182M6Q1   A0A1S3D309   A0A0A1WEB3   B4PA36   A0A0A1WMP6   A0A182WJC4   B4HQM8   A0A182KR71   A0A182UHI7   A0A1L8DHN9   A0A182PQJ6   A0A1L8DHW3   A0A443S6H7   A0A0K8WBE7   A0A182I364   E0VJY7   T2MAG2   U5D144   A0A1S3J0D6   A0A1Y9H9F2   A0A0D6R320   A0A1B6D014   A0A087SYA8   A0A1X7UH48   A0A2J7PHD8   E9H210   W5UDQ8   A0A287A202   K4AFB7   A0A452DV91   A0A1U7R2K0   W5QF38   A0A067QW52   T1HN26   A0A443RQ77   A0A1A6HTU9   J9K8U0   A4IG71   K4ADP5   A0A293M8X2   A0A0A0LUP4   A0A3B1JK95   F1R994   A0A1Y1JX87   A0A2Y9DCQ3   A0A0D9VQV4   A0A3B1IRF6   G1SNT6  

PDB

1JCU     E-value=1.32817e-19,     Score=235

KEGG

692853    no KO assigned | (RefSeq) ischemia/reperfusion inducible protein

GO

GO:0003725   GO:0006351   GO:0003899   GO:0008270   GO:0042779   GO:0016779   GO:0005737   GO:0000049   GO:0006450   GO:0016020   GO:0008236   GO:0008033   GO:0005524   GO:0061710   GO:0051051   GO:0019898   GO:0005856   GO:0006108   GO:0030060   GO:0016615   GO:0016876  

Subcellular location

Cytoplasm  

Length:

274

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.20541

Exp number, first 60 AAs:

0.18838

Total prob of N-in:

0.04716

outside

1  -  274

 

 

Pi

39.361708

Theta

23.90013

Tajima's D

-0.606868

CLR

0

CSRT

0.220488975551222

Interpretation

Uncertain