Gene

KWMTBOMO09416  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013085

Annotation

Carboxypeptidase_[Operophtera_brumata]

Location

Bomo_Chr16(-):940647-942276      View in EpiBrowser

Full name

Carboxypeptidase       + More
Venom serine carboxypeptidase      

Location in the cell

Lysosomal   Reliability : 1.392

CDS

ATGTATCAAGTTTTGTTGTTGATAACCATTTTGTCAGAGGCCCGGGCCTTCCTGCATCACTATCCGAAATTAAATCTCGGAGAGCGAGATGGCGGGGACCCTGGTGAGCCTTTGTTCCTTACGCCATATGTGGAAAGCGGTAACATCACTACAGGGAGGCGTCTAGCCAGAGTACCATTTACTGAAAGCCTGCGCATTAAAAGTTATGCAGGCTACTTCACGGTAAATAAGACTTACGACTCCAACCAGTTCTTCTGGTACTTTCCTGCTATGGTTCCGAACAGCAAAAACGCACCGATTATCGTCTGGCTCCAAGGAGGCCCCGGCGCTACATCTCTGTATGGACTCTTCACAGAAAACGGTCCTTTAAGGGTTCGCAATAAGAAGTTTGAGAGACGAAAGTATAACTGGGCCCTCAGTCATCATATTATATATATTGACAACCCTGTTGGCACTGGATTCAGTTTCACTAAAGATCCTAAAGGCTACTGTGTTGATGAGACTCAAGTTGGCGAACAGTTATACTCCACTCTGATCCAGTTCTTCCAGTTGTTTCCAGAACTTCAAACCAATAATTTTTTTGTGACTGGAGAATCATATGGAGGAAAGTATGTACCAGCTCTGGCCTACACAATTCACAAGAAAAATCCTACAGCACAGATTAAAATTAATATGAAGGGTATTGCAATAGGAAATGGTTTGAGTGACCCTGTACATCAGCTCGTGTATGGTAAATATCTGTATCAAATAGGATTAATTGACTGGAACCAGGCTAAAGTATTTGAACAGTATGAAAATAAGACAAAAGATTTCATAAAGCAGGGAGAGTGGGATAAAGCGTTTGAGACCTTTGACACCTTGTTGAATGGTGACATGTTGAATGGATCAAGTGTTTTTAAAAACATGACTGGTTTTGATTTTTACTTTAACTACCTCCACACTAAGGATTATACACAGTTTGAGGACTTTGGCCCAATGCTTCAAAGAAGTGCAGTCCGCAAAGCCATACACGTTGGAAACTTACCGTTTAATAATGGAACTGAAGTTGAGAAGCATCTGAAGCAAGATGTGATGAAGTCAGTAGCACCTTGGATAGCAGAACTATTGGACAATTATTATATCGTTATCTACAATGGTCAGCTAGATATTATAGTAGCATATCCTTTGACTGTTAATTATTTAAGAAACCTCAATTTTACTGGATCTGATGAGTATAAGACTGCAAAACGGTACATTTGGAAGGTGGATGGAGAGGTTGCAGGTTATGTGAAGCAAGCTGGAAAACTTGTTGAAATTTTAGTCAGAAATGCAGGTCATATGGTGCCCGGAGATCAGCCAAAATGGGCTTTAGACTTGATTACTAGGTTCACCCATGAGAAAACCTACTTTGATAAAGCTGAAATTGGTCAAACTTTGGGTTCTTTGTAA

Protein

MYQVLLLITILSEARAFLHHYPKLNLGERDGGDPGEPLFLTPYVESGNITTGRRLARVPFTESLRIKSYAGYFTVNKTYDSNQFFWYFPAMVPNSKNAPIIVWLQGGPGATSLYGLFTENGPLRVRNKKFERRKYNWALSHHIIYIDNPVGTGFSFTKDPKGYCVDETQVGEQLYSTLIQFFQLFPELQTNNFFVTGESYGGKYVPALAYTIHKKNPTAQIKINMKGIAIGNGLSDPVHQLVYGKYLYQIGLIDWNQAKVFEQYENKTKDFIKQGEWDKAFETFDTLLNGDMLNGSSVFKNMTGFDFYFNYLHTKDYTQFEDFGPMLQRSAVRKAIHVGNLPFNNGTEVEKHLKQDVMKSVAPWIAELLDNYYIVIYNGQLDIIVAYPLTVNYLRNLNFTGSDEYKTAKRYIWKVDGEVAGYVKQAGKLVEILVRNAGHMVPGDQPKWALDLITRFTHEKTYFDKAEIGQTLGSL

Catalytic Activity

Release of a C-terminal amino acid with broad specificity.

Similarity

Belongs to the peptidase S10 family.
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

Keywords

Allergen   Carboxypeptidase   Complete proteome   Glycoprotein   Hydrolase   Protease   Reference proteome   Secreted   Signal  

Feature

chain  Carboxypeptidase

Uniprot

H9JU73   A0A2A4K7Y2   A0A2H1VKQ6   A0A0L7LM79   A0A1E1WAZ3   A0A194RR51   + More
S4P7T7   A0A194Q054   I4DN75   A0A194RR56   A0A194Q1S4   A0A212FM72   B0WNR6   A0A336M8H4   A0A1S4FM29   A0A1Q3F8Y0   Q16W90   A0A182BVG2   A0A182FF64   A0A1Q3F8R6   A0A182I3C9   A0A084WNC9   A0A182VEU0   A0A182X3P0   W5J9B8   A0A182KRE8   A0A182U5W4   A0A182HBE4   A0A195D9Z9   Q7QJG6   U4U2S4   F4X0L6   D7EHX7   A0A195B917   A0A182WJ64   A0A158ND03   A0A151WYN0   A0A195F7F6   A0A195D1V5   A0A182K218   A0A182MJA6   A0A0L7R680   A0A1B6EFH6   C9WMM5   U5EN01   A0A336M6M0   A0A182XYY3   A0A2A3EHH5   A0A1V1FIY0   E2AY00   A0A336M9T2   A0A026WJK0   K7IV06   A0A182PQD1   A0A182J314   A0A0M8ZQT3   A0A348G5Z8   A0A182NHT4   E9IJU5   A0A1B6FEW7   A0A067QKM7   A0A182QKM9   A0A2J7RDU7   A0A1Y1LX67   A0A0A9XV56   A0A3R7QLR9   A0A0A9XKA6   A0A0J7KEF9   A0A146LT64   A0A182H8I5   A0A1J1IBF1   Q49B95   A0A1B6KAA3   A0A1Q3F9Y2   A0A1Q3F9S6   Q175U3   A0A0A9XQP3   R4WHX6   A0A1B0D2X8   B0WT67   A0A182BVG3   A0A1B0D870   A0A1L8DP70   A0A0M5J9U2   B3LXS4   A0A194RSA4   R4FLC5   A0A194Q6A2   A0A170XJP7   A0A224XJN6   A0A3B0JNA7   A0A2H1VMC9   Q294S7   B4QST7   B4LP47   B4PNK5   A0A2A4K6A6   A0A2R7WTA9   B4KLQ9   B4LJX3  

EC Number

3.4.16.-
3.4.16.5

Pubmed

19121390    26227816    26354079    23622113    22651552    22118469    + More
17510324    24438588    20920257    23761445    20966253    26483478    12364791    14747013    17210077    23537049    21719571    18362917    19820115    21347285    17073008    25244985    28410430    20798317    24508170    30249741    20075255    21282665    24845553    28004739    25401762    26823975    16431282    23691247    17994087    15632085    17550304   

EMBL

BABH01004187    NWSH01000086    PCG79770.1    ODYU01003090    SOQ41405.1    JTDY01000595    + More
KOB76535.1    GDQN01006939    JAT84115.1    KQ459700    KPJ20358.1    GAIX01004449    JAA88111.1    KQ459582    KPI98941.1    AK402751    BAM19365.1    KPJ20363.1    KPI98944.1    AGBW02007654    OWR54827.1    DS232014    EDS31907.1    UFQT01000606    SSX25661.1    GFDL01011072    JAV23973.1    CH477572    EAT38860.1    KU179862    AND61387.1    GFDL01011075    JAV23970.1    APCN01000205    ATLV01024587    KE525352    KFB51723.1    ADMH02001806    ETN61052.1    JXUM01031871    KQ560938    KXJ80263.1    KQ981135    KYN09229.1    AAAB01008807    EAA04657.4    KB631843    ERL86633.1    GL888498    EGI60008.1    KQ971323    KYB28573.1    KQ976558    KYM80684.1    ADTU01012128    KQ982650    KYQ52877.1    KQ981744    KYN36373.1    KQ977012    KYN06384.1    AXCM01000691    KQ414646    KOC66387.1    GEDC01000657    JAS36641.1    FJ765738    GANO01000788    JAB59083.1    SSX25660.1    KZ288242    PBC31235.1    FX985408    BAX07421.1    GL443740    EFN61703.1    SSX25659.1    KK107213    QOIP01000007    EZA55299.1    RLU20576.1    AAZX01001162    KQ435896    KOX69240.1    FX985537    BBF97871.1    GL763883    EFZ19168.1    GECZ01027718    GECZ01021024    GECZ01020517    GECZ01014025    JAS42051.1    JAS48745.1    JAS49252.1    JAS55744.1    KK853243    KDR09452.1    AXCN02000377    NEVH01005284    PNF39003.1    GEZM01050301    JAV75627.1    GBHO01022474    GBHO01022473    GBHO01022471    GBHO01003884    JAG21130.1    JAG21131.1    JAG21133.1    JAG39720.1    QCYY01000750    ROT83024.1    GBHO01022472    JAG21132.1    LBMM01008690    KMQ88692.1    GDHC01008170    JAQ10459.1    JXUM01029016    KQ560839    KXJ80664.1    CVRI01000047    CRK97539.1    AY962406    AAY27740.1    GEBQ01031843    JAT08134.1    GFDL01010661    JAV24384.1    GFDL01010711    JAV24334.1    CH477395    EAT41862.1    GBHO01022476    JAG21128.1    AK416960    BAN20175.1    AJVK01023133    DS232080    EDS34210.1    KU179863    AND61388.1    AJVK01027239    GFDF01005801    JAV08283.1    CP012524    ALC40556.1    CH902617    EDV41731.1    KPJ20357.1    ACPB03001109    GAHY01001473    JAA76037.1    KPI98940.1    GEMB01004337    JAR98936.1    GFTR01006388    JAW10038.1    OUUW01000008    SPP83704.1    SOQ41404.1    CM000070    EAL28887.1    CM000364    EDX12297.1    CH940648    EDW62241.1    CM000160    EDW96068.1    PCG79771.1    KK855397    PTY22370.1    CH933808    EDW08695.1    EDW61627.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053240    UP000053268    UP000007151    + More
UP000002320    UP000008820    UP000069272    UP000075840    UP000030765    UP000075903    UP000076407    UP000000673    UP000075882    UP000075902    UP000069940    UP000249989    UP000078492    UP000007062    UP000030742    UP000007755    UP000007266    UP000078540    UP000075920    UP000005205    UP000075809    UP000078541    UP000078542    UP000075881    UP000075883    UP000053825    UP000005203    UP000076408    UP000242457    UP000000311    UP000053097    UP000279307    UP000002358    UP000075885    UP000075880    UP000053105    UP000075884    UP000027135    UP000075886    UP000235965    UP000283509    UP000036403    UP000183832    UP000092462    UP000092553    UP000007801    UP000015103    UP000268350    UP000001819    UP000000304    UP000008792    UP000002282    UP000009192   

PRIDE

H9JU73   

Pfam

PF00450   Peptidase_S10        + More
PF00083   Sugar_tr

Interpro

IPR001563   Peptidase_S10        + More
IPR029058   AB_hydrolase       
IPR033124   Ser_caboxypep_his_AS       
IPR018202   Ser_caboxypep_ser_AS       
IPR003663   Sugar/inositol_transpt       
IPR005828   MFS_sugar_transport-like       
IPR036259   MFS_trans_sf       
IPR005829   Sugar_transporter_CS       
IPR020846   MFS_dom       

SUPFAM

SSF53474   SSF53474        + More
SSF103473   SSF103473       

Gene 3D

3.40.50.1820    

CDD

cd06174  MFS

ProteinModelPortal

H9JU73   A0A2A4K7Y2   A0A2H1VKQ6   A0A0L7LM79   A0A1E1WAZ3   A0A194RR51   + More
S4P7T7   A0A194Q054   I4DN75   A0A194RR56   A0A194Q1S4   A0A212FM72   B0WNR6   A0A336M8H4   A0A1S4FM29   A0A1Q3F8Y0   Q16W90   A0A182BVG2   A0A182FF64   A0A1Q3F8R6   A0A182I3C9   A0A084WNC9   A0A182VEU0   A0A182X3P0   W5J9B8   A0A182KRE8   A0A182U5W4   A0A182HBE4   A0A195D9Z9   Q7QJG6   U4U2S4   F4X0L6   D7EHX7   A0A195B917   A0A182WJ64   A0A158ND03   A0A151WYN0   A0A195F7F6   A0A195D1V5   A0A182K218   A0A182MJA6   A0A0L7R680   A0A1B6EFH6   C9WMM5   U5EN01   A0A336M6M0   A0A182XYY3   A0A2A3EHH5   A0A1V1FIY0   E2AY00   A0A336M9T2   A0A026WJK0   K7IV06   A0A182PQD1   A0A182J314   A0A0M8ZQT3   A0A348G5Z8   A0A182NHT4   E9IJU5   A0A1B6FEW7   A0A067QKM7   A0A182QKM9   A0A2J7RDU7   A0A1Y1LX67   A0A0A9XV56   A0A3R7QLR9   A0A0A9XKA6   A0A0J7KEF9   A0A146LT64   A0A182H8I5   A0A1J1IBF1   Q49B95   A0A1B6KAA3   A0A1Q3F9Y2   A0A1Q3F9S6   Q175U3   A0A0A9XQP3   R4WHX6   A0A1B0D2X8   B0WT67   A0A182BVG3   A0A1B0D870   A0A1L8DP70   A0A0M5J9U2   B3LXS4   A0A194RSA4   R4FLC5   A0A194Q6A2   A0A170XJP7   A0A224XJN6   A0A3B0JNA7   A0A2H1VMC9   Q294S7   B4QST7   B4LP47   B4PNK5   A0A2A4K6A6   A0A2R7WTA9   B4KLQ9   B4LJX3  

PDB

1IVY     E-value=8.33772e-38,     Score=395

KEGG

101740973    K09645 vitellogenic carboxypeptidase-like protein [EC:3.4.16.-] | (RefSeq) venom serine carboxypepti

GO

GO:0004185   GO:0016021   GO:0051603   GO:0005576   GO:0022857   GO:0033227   GO:0006508   GO:0015074   GO:0004672   GO:0005524   GO:0006468   GO:0006418   GO:0000049   GO:0016876  

PANTHER

PTHR11802  

Subcellular location

Secreted  

SignalP

Position:   1 - 16,         Likelihood:  0.937931

 

 

Length:

475

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.274360000000001

Exp number, first 60 AAs:

0.0076

Total prob of N-in:

0.00561

outside

1  -  475

 

 

Pi

242.469385

Theta

233.580171

Tajima's D

0.161231

CLR

0.404992

CSRT

0.417779111044448

Interpretation

Uncertain