Gene

KWMTBOMO09375

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr16(+):70816-75440      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.607 Nuclear   Reliability : 1.561 PlasmaMembrane   Reliability : 1.098

CDS

ATGGACGCTGTATTCGCGGAATTCCTCCGACTTCGCCACCCACAGCTCGCCTCGGAGTTTTTGGCCTTCAAGGCCAATCACACTGCGAGCCCTCTCGAGGACTCCGCCGCGCTCGCTGCTCCTGCGTCGCCTGTACCTGCGTGCAGAGCTTCTGCATTGAGCACCGCAGCCTCTGTCGTGCCTGCCGCTCCCGTGTCGCCTATACTGGCGAGAAAAGCTGCTGCGTCGTCCGCCGTGACCATCGTTTCAGCTGAGCGATCATCCGCGGCCTCCGTCGCGCCCTCTAAAACACCTACACTTGCTCGTAGGTCGCCTGCACCCGCCTCCTCGTGCTCCGACTCTGACTCGGACATGGAGGTCGACCTCGCCCCCGCCTCATCGACGGATGGATTCACCCTGGTACAGAAGGGTAAGAAGCGTGCCGCGGAGTCTCGAGCTCCCGCGGCCGCTAAAATTAGCAAAGCCGTGAACGCGTCGCGCCCCCGCCCTCAGACTCCCGTTGCGCCCCCAGCCCGTGCCACTCCGTCGCCGCGTCCGGTGGCACAAAATAAAACCCAGACCCCTCCCCCGGTTATCCTTCAGGAGAAGGCAGCTTGGGATCGAGTTTGCCTGGCCCTTAAGGCCAAAAATATAAATTTCACGAATGCCCGTAACCTCGCGAACGGCATTCAAATTAAGGTTCAAACACCCGACGACCATAGGGCCCTCTCTTCTTACCTCCGTAAGGAGCGTATAAGTTTCCATACGTATACGCTCCAGGAGGAGCGCGAACTCCGCGTTGTAATACGCGGAATCCCTAAAGAGTTAGATGTAGAGCTCGTAAAAGCCGACCTGTTAGAACAAAGCCTACCAGTGAATTCTGTGCACCGTATGCACACCGGTCGCGGTAGGGAGCCATATAATATGGTTCTAGTCGCTCTCCAGCCTACCCCGAGGGAGACCCTACTTAAGCCCGCGCGCCGTGACCCTAAAATCGCGAACTATAACATGGTCAGGAACGACAGGCTCTCTGCCCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGTATGGGGAGCTCTGCCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGCTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTTCCGTTTAGTCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCGTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAGCAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGCCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATCCGTGCGTACGATAGGTATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGTGACGTAAAGTCTCGCATCACCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCTCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATCCCCCGATCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGGAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAA

Protein

MDAVFAEFLRLRHPQLASEFLAFKANHTASPLEDSAALAAPASPVPACRASALSTAASVVPAAPVSPILARKAAASSAVTIVSAERSSAASVAPSKTPTLARRSPAPASSCSDSDSDMEVDLAPASSTDGFTLVQKGKKRAAESRAPAAAKISKAVNASRPRPQTPVAPPARATPSPRPVAQNKTQTPPPVILQEKAAWDRVCLALKAKNINFTNARNLANGIQIKVQTPDDHRALSSYLRKERISFHTYTLQEERELRVVIRGIPKELDVELVKADLLEQSLPVNSVHRMHTGRGREPYNMVLVALQPTPRETLLKPARRDPKIANYNMVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSAILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFSPDSIPSPQDTAEAIDIVTSHITSTLDRSSKQVVAEDFLHRFKLPDDIRELLRAKNASIRAYDRYPTAENRIRMRALQRDVKSRITEVRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASERYFDKAMRHDNRLIVAAADYSRILIMQEPVTVDALDTSLRIHQIQ

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139W8G9   A0A139WA11   X1WLB2   V5GNF3   A0A023EYS8   A0A2S2PPK8   X1WNI2   A0A023EZE6   A0A2S2QEE0   X1WZH0   A0A2J7Q6J2   A0A224XB44   A0A2J7PU96   A0A2J7R7D0   A0A2J7QR37   A0A224X6Q4   A0A2J7PBY3   A0A2J7QY69   K7IN67   A0A2J7QB68   A0A2S2Q383   A0A224X6S1   A0A2J7PQB5   A0A2J7PDM0   A0A224X6T4   A0A0A9YJ00   A0A069DZL8   J9LFC9   A0A224XI99   A0A224X6U5   A0A2S2NGV8   A0A3N5Z7I3   A0A2H8TF37   A0A2M4BD67   A0A2M4BDV6   A0A2S2NH02   Q07995   A0A2S2R9D4   A0A224X746   Q9NBX4   A0A2S2N6Q7   A0A2J7PVX3   A0A224XIB0   A0A2S2PJG2   A0A352X8G4   A0A1Y1KFR3   Q95SX7   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD83   A0A142LX49   A0A2M4BD62   A0A2H8TKI9   A0A2S2NPG3   A0A142LX26   A0A0V0G5B6   A0A224X6R6   A0A2S2P698   A0A023F069   A0A069DX78   A0A023F0I3   Q8T9X4   A0A2S2P6S3   Q8I7P8   Q24335   A0A2J7Q0S7   A0A2S2P3X8  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    20075255    25401762    26334808    30086797    8387152    11405632    30148503    7753626    12537569    25527032    2441397   

EMBL

U07847    AAA17752.1    AB055391    BAB21761.1    AB018558    BAA76304.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    ABLF02042518    ABLF02057746    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    ABLF02008153    ABLF02008462    ABLF02008464    GBBI01004571    JAC14141.1    GGMS01006359    MBY75562.1    ABLF02034467    NEVH01017470    PNF24199.1    GFTR01008262    JAW08164.1    NEVH01021205    PNF19912.1    NEVH01006736    PNF36716.1    NEVH01011985    PNF31054.1    GFTR01008279    JAW08147.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    NEVH01016302    PNF25823.1    GGMS01002992    MBY72195.1    GFTR01008271    JAW08155.1    NEVH01022639    PNF18527.1    NEVH01026386    PNF14434.1    GFTR01008261    JAW08165.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GBGD01000415    JAC88474.1    ABLF02023911    GFTR01008256    JAW08170.1    GFTR01008251    JAW08175.1    GGMR01003407    MBY16026.1    RPOV01000134    RPJ78669.1    GFXV01000908    MBW12713.1    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    GGMR01003864    MBY16483.1    S59870    AAB26437.2    GGMS01017365    MBY86568.1    GFTR01008151    JAW08275.1    AF237761    AAF81411.1    GGMR01000226    MBY12845.1    NEVH01020940    PNF20481.1    GFTR01008246    JAW08180.1    GGMR01016905    MBY29524.1    DNOY01000259    HBE18313.1    GEZM01084969    JAV60363.1    AY060438    AAL25477.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001822    MBW50963.1    KU543685    AMS38375.1    GGFJ01001843    MBW50984.1    GFXV01002840    MBW14645.1    GGMR01006408    MBY19027.1    KU543673    AMS38352.1    GECL01003538    JAP02586.1    GFTR01008269    JAW08157.1    GGMR01012305    MBY24924.1    GBBI01003810    JAC14902.1    GBGD01000389    JAC88500.1    GBBI01003747    JAC14965.1    AF456125    AAL57609.1    GGMR01012443    MBY25062.1    AY180919    AAN87272.1    M17214    AAA28508.1    NEVH01019963    PNF22185.1    GGMR01011511    MBY24130.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000002358   

PRIDE

Q93137    Q9BPQ0    Q9XXW0    Q9NBX4    Q95SX7    Q8T9X4    + More
Q8I7P8    Q24335   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139W8G9   A0A139WA11   X1WLB2   V5GNF3   A0A023EYS8   A0A2S2PPK8   X1WNI2   A0A023EZE6   A0A2S2QEE0   X1WZH0   A0A2J7Q6J2   A0A224XB44   A0A2J7PU96   A0A2J7R7D0   A0A2J7QR37   A0A224X6Q4   A0A2J7PBY3   A0A2J7QY69   K7IN67   A0A2J7QB68   A0A2S2Q383   A0A224X6S1   A0A2J7PQB5   A0A2J7PDM0   A0A224X6T4   A0A0A9YJ00   A0A069DZL8   J9LFC9   A0A224XI99   A0A224X6U5   A0A2S2NGV8   A0A3N5Z7I3   A0A2H8TF37   A0A2M4BD67   A0A2M4BDV6   A0A2S2NH02   Q07995   A0A2S2R9D4   A0A224X746   Q9NBX4   A0A2S2N6Q7   A0A2J7PVX3   A0A224XIB0   A0A2S2PJG2   A0A352X8G4   A0A1Y1KFR3   Q95SX7   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD83   A0A142LX49   A0A2M4BD62   A0A2H8TKI9   A0A2S2NPG3   A0A142LX26   A0A0V0G5B6   A0A224X6R6   A0A2S2P698   A0A023F069   A0A069DX78   A0A023F0I3   Q8T9X4   A0A2S2P6S3   Q8I7P8   Q24335   A0A2J7Q0S7   A0A2S2P3X8  

KEGG

105841788    no KO assigned | (RefSeq) predicted GPI-anchored protein 58

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1162

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.9929

Exp number, first 60 AAs:

0.00071

Total prob of N-in:

0.00013

outside

1  -  1162

 

 

Pi

0.00893

Theta

0.040926

Tajima's D

-0.391696

CLR

245.647802

CSRT

0.0677966101694915

Interpretation

Uncertain