Gene

KWMTBOMO09346

Pre Gene Modal

BGIBMGA002171

Annotation

PREDICTED:_probable_cytochrome_P450_9f2_[Bombyx_mori]

Location

Bomo_Chr15(-):17253437-17263635      View in EpiBrowser

Full name

Cytochrome P450 9e2       + More
Probable cytochrome P450 9f2      

Alternative Name

CYPIXE2
CYPIXF2

Location in the cell

PlasmaMembrane   Reliability : 2.733

CDS

ATGTTCCTTGAAACATTACTATTATTAATAACGATAATAGTAGGCTATTATTGGTACATTTATAAGAAAGCTCATTATTATTTTGAATCGAAAGGGGTCAAATACTTACGTGGCGTACCTTTCTTTGGGAATCTCATGAATAATTTGTTGAGGAGAACGCATTTGTGGGAGGACTATGATGTAGTCTATAAAGCTTTTCCCAATGAGAGATACGTTGGCTTTACCGACGGCGTCTGTCCGGGCATCTTTATTCGCGATCCTGAGATTATAAAACATGTTACAGTTAAGGAATTTGATCATTTCGTCAACAACAAGGATTTGTCCCCAGAAGGAGAGGAGTCAATTTTAAAAAACAGCTTGATAATGCTGAAAGCAATCGGGCGCGAACTGTATGGTCACGAGTCGCTGATCGCGAGTGAACGATTTTATTTCACTAATCTGCAACTTGTTTCAGATGAAAAATGGCGGAAAATGAGAGCAGCTCTTAGTCCAGCGTTTACTGCATCTAAAATGAGAGAAATGGTCCCATTAATTACTGAAATCAGTCACAATATCGTTGAATACTTGAAAGAACACCTAACTGAAGACATAGATTTAGATGACTTGATGTCCAGGTATTCTAATGACGTCATTGCATCAGCAGCTTTCGGCCTCCAAATAAACTCGTTGAAAGAAAGAGACAACATCTTCTTCAGGGCAGGAAAAGATGTGTTTAATTTTAGCCTCTTTCAATCAATTCTTATGATTTTTTCAGACCACTTTCCATCTTTATCGAAGAAACTAGGATTCACAATCATACCTAAATCAACATCAGAATTCTTCCGGACTCTAATAGCTAGTACCGTGGACTATAGAATAAAAAATAAAGTTGAAAGACGTGACATGATACAGTTGTTAATGCAATTATCGACAGAATGGACAGAGACTGAGCTAGCCGCCCAACTTTTCGTGTTCTTCGTTGCTGGATTTGAGACCACAGGAAACACTTTGATCAACTGTATTCATGAATTAGCCCTAAGCCCGCATATTCAGGATATCCTATATGAGGAGTTGAAGGCTTTCAAGGAGACTAAAGGAAATCTGGTTTATGAAAATATTGGGGAATTAAAATACTTAGATTGCGTTTTAAATGAAACGATGAGGAAATGGTCTGCTGCAATCTTTGTTGACAGGATCTGTACGAAGCCATATGTCCTTCCACCGCCCAGGGAAGGGGGCAAACCGTGCCAGCTAAAACCTGGTGAAGTAATATACAACACAGTAAATTCAATTCATATGGATCCAATATACTATGAAGAACCTGAGAAATTTATCCCGGAAAGGTTCTTAGATGAGAACAAGCATAAAATCAAACCATTTACTTTCATGCCATTCGGAGTTGGACCAAGATATTGTATTGGATCAAGGTTCGCTCTGATGGAGATGAAGATATTACTCTTCCGCTTGATGCTAAATTTCAAGGTCTTGAAATGCGCGAAGACTCTGGATCCGATAAAAATGTCGCCAGTAGGATTCAACATGAATATATGGGGTGGTAGCTGGGTGAAATTTCAGGCCAGAAAGGCGTAA

Protein

MFLETLLLLITIIVGYYWYIYKKAHYYFESKGVKYLRGVPFFGNLMNNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKAIGRELYGHESLIASERFYFTNLQLVSDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLKEHLTEDIDLDDLMSRYSNDVIASAAFGLQINSLKERDNIFFRAGKDVFNFSLFQSILMIFSDHFPSLSKKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERRDMIQLLMQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKMSPVGFNMNIWGGSWVKFQARKA

Description

May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.

Cofactor

heme

Similarity

Belongs to the cytochrome P450 family.

Keywords

Endoplasmic reticulum   Heme   Iron   Membrane   Metal-binding   Microsome   Monooxygenase   Oxidoreductase   Alternative splicing   Complete proteome   Reference proteome  

Feature

chain  Cytochrome P450 9e2
splice variant  In isoform B.

Uniprot

B1AAB3   A0A0C5BXE6   A0A194RNT1   A0A0N1I524   A0A1V0D9E3   A0A068EU90   + More
A0A212F2Z7   A0A411E5G6   A0A2W1BY21   A0A0N1PH22   B5TVL6   A0A2H1VQ44   L0N4K9   A0A194RJE6   A0A411K6Z7   A0A0A1WSM0   K7IVB0   E9IKB9   T1PHF2   Q9U9C1   A0A411K6X4   A0A1W6L1G4   A0A0K8WK49   A0A232EJW7   E2AZV5   F4W6Z7   A0A158NME4   A0A2J7Q4A7   A0A195AXM8   A0A0J7KT89   A0A0L7QRI0   A0A151K0H6   A0A1I8PZU3   A0A348G632   F4W704   A0A195AXM2   A0A411K724   A0A1L8E3Z9   A0A286KR98   B4HGZ1   A0A0J7KSZ5   A0A2J7Q4A3   A0A125S6Q0   A0A158NNZ7   A0A212F6B9   B4QSW0   A0A1I8PNF7   A0A034WH75   A0A1W6L1D6   M1NJY9   W8B143   A0A1A9W7C0   A0A087ZXU2   A0A154P136   A0A068F5G5   A0A1W6L1I6   J7FIT3   A0A154P0V6   A0A0L0BY58   A0A151X7X3   A0A1Y1L0G7   A0A0J7K779   A0A2J7QR65   A0A087ZXU3   Q964T2   G3CLK5   A0A026WP90   Q9VG82   B4NBE7   A0A151X7V4   A0A3L8D429   A0A195DAZ9   A0A0J7KF62   A0A0J7K8G3   A0A2A3EAA2   A0A1I8NDV3   E2AZV6   B3P1B7   A0A1I8NNJ6   E9JBX4   A0A3B0JEF6   A0A3L8D5E9   B0WDJ0   A0A026VV18   A0A154P160   A0A3L8DQ44   B4PNS7   A0A195C3P8   A0A3L8D4L2   A0A310SK73   A0A3L8D538   A0A2J7PTN7   A0A1Y1KP85   A0A1L8ECA7   B4M454   A0A2A3EB45   A0A310SNJ3   A0A1Y1KGP9   A0A0J7KFB9  

EC Number

1.14.-.-

Pubmed

26354079    22118469    28756777    30716069    25830018    20075255    + More
21282665    25315136    10844248    28648823    20798317    21719571    21347285    17994087    25348373    23454142    24495485    25880816    22984814    26108605    28004739    11470532    23262344    24508170    10731132    12537572    12537569    30249741    17550304   

EMBL

EU435134    AK343210    AK343211    ABZ81070.1    BAM73894.1    BAM73895.1    + More
KP001128    AJN91173.1    KQ460124    KPJ17676.1    KQ459169    KPJ03414.1    KY212056    ARA91620.1    KM016757    AID54909.1    AGBW02010648    OWR48107.1    MH236466    QBA57471.1    KZ149921    PZC77720.1    KPJ03415.1    FJ023535    ACH88357.1    ODYU01003748    SOQ42906.1    AK289307    BAM73834.1    KPJ17677.1    MH500629    QBC73104.1    GBXI01012874    JAD01418.1    AAZX01001170    GL763964    EFZ18984.1    KA647545    AFP62174.1    AF172279    AAD51036.1    MH500607    QBC73082.1    KX609531    ARN17938.1    GDHF01000788    JAI51526.1    NNAY01003923    OXU18647.1    GL444277    EFN61084.1    GL887802    EGI69987.1    ADTU01002256    NEVH01018386    PNF23399.1    KQ976716    KYM76795.1    LBMM01003502    KMQ93459.1    KQ414784    KOC61106.1    KQ981253    KYN44191.1    FX985571    BBF97905.1    EGI69994.1    KYM76790.1    MH500628    QBC73103.1    GFDF01000616    JAV13468.1    KX708490    ARG41837.1    CH480815    EDW42462.1    KMQ93458.1    KMQ93460.1    PNF23410.1    KT601142    AME15811.1    ADTU01002276    AGBW02010052    OWR49281.1    CM000364    EDX13220.1    GAKP01004021    JAC54931.1    KX609540    ARN17947.1    JX861089    AGF69215.1    GAMC01014338    JAB92217.1    KQ434796    KZC05571.1    KJ702304    AID61458.1    KX609535    ARN17942.1    JX310084    AFP20595.1    KZC05569.1    JRES01001160    KNC24973.1    KQ982431    KYQ56463.1    GEZM01068125    JAV67162.1    LBMM01012632    KMQ86094.1    NEVH01011934    PNF31078.1    AF275640    HQ113142    AEL88550.1    KK107147    EZA57476.1    AE014297    AY058466    CH964232    EDW81111.1    KYQ56461.1    QOIP01000013    RLU15267.1    KQ981042    KYN10063.1    LBMM01008395    KMQ88919.1    LBMM01011986    KMQ86506.1    KZ288308    PBC28693.1    EFN61085.1    CH954181    EDV49376.1    GL771642    EFZ09702.1    OUUW01000005    SPP80485.1    RLU15243.1    DS231898    EDS44599.1    KK107839    EZA47525.1    KZC05573.1    QOIP01000005    RLU22362.1    CM000160    EDW97092.1    KQ978344    KYM94811.1    RLU15176.1    KQ762107    OAD56182.1    RLU15510.1    NEVH01021235    PNF19689.1    GEZM01084793    JAV60677.1    GFDG01002485    JAV16314.1    CH940652    EDW59415.1    PBC28694.1    KQ761834    OAD56684.1    GEZM01084791    JAV60679.1    LBMM01008321    LBMM01008267    KMQ88979.1    KMQ89015.1   

Proteomes

UP000053240    UP000053268    UP000007151    UP000002358    UP000095301    UP000215335    + More
UP000000311    UP000007755    UP000005205    UP000235965    UP000078540    UP000036403    UP000053825    UP000078541    UP000095300    UP000001292    UP000000304    UP000091820    UP000005203    UP000076502    UP000037069    UP000075809    UP000053097    UP000000803    UP000007798    UP000279307    UP000078492    UP000242457    UP000008711    UP000268350    UP000002320    UP000002282    UP000078542    UP000008792   

PRIDE

B1AAB3    L0N4K9    Q964T2    Q9VG82   

Pfam

PF00067   p450

Interpro

IPR036396   Cyt_P450_sf        + More
IPR002401   Cyt_P450_E_grp-I       
IPR001128   Cyt_P450       
IPR017972   Cyt_P450_CS       
IPR002403   Cyt_P450_E_grp-IV       
IPR002402   Cyt_P450_E_grp-II       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

B1AAB3   A0A0C5BXE6   A0A194RNT1   A0A0N1I524   A0A1V0D9E3   A0A068EU90   + More
A0A212F2Z7   A0A411E5G6   A0A2W1BY21   A0A0N1PH22   B5TVL6   A0A2H1VQ44   L0N4K9   A0A194RJE6   A0A411K6Z7   A0A0A1WSM0   K7IVB0   E9IKB9   T1PHF2   Q9U9C1   A0A411K6X4   A0A1W6L1G4   A0A0K8WK49   A0A232EJW7   E2AZV5   F4W6Z7   A0A158NME4   A0A2J7Q4A7   A0A195AXM8   A0A0J7KT89   A0A0L7QRI0   A0A151K0H6   A0A1I8PZU3   A0A348G632   F4W704   A0A195AXM2   A0A411K724   A0A1L8E3Z9   A0A286KR98   B4HGZ1   A0A0J7KSZ5   A0A2J7Q4A3   A0A125S6Q0   A0A158NNZ7   A0A212F6B9   B4QSW0   A0A1I8PNF7   A0A034WH75   A0A1W6L1D6   M1NJY9   W8B143   A0A1A9W7C0   A0A087ZXU2   A0A154P136   A0A068F5G5   A0A1W6L1I6   J7FIT3   A0A154P0V6   A0A0L0BY58   A0A151X7X3   A0A1Y1L0G7   A0A0J7K779   A0A2J7QR65   A0A087ZXU3   Q964T2   G3CLK5   A0A026WP90   Q9VG82   B4NBE7   A0A151X7V4   A0A3L8D429   A0A195DAZ9   A0A0J7KF62   A0A0J7K8G3   A0A2A3EAA2   A0A1I8NDV3   E2AZV6   B3P1B7   A0A1I8NNJ6   E9JBX4   A0A3B0JEF6   A0A3L8D5E9   B0WDJ0   A0A026VV18   A0A154P160   A0A3L8DQ44   B4PNS7   A0A195C3P8   A0A3L8D4L2   A0A310SK73   A0A3L8D538   A0A2J7PTN7   A0A1Y1KP85   A0A1L8ECA7   B4M454   A0A2A3EB45   A0A310SNJ3   A0A1Y1KGP9   A0A0J7KFB9  

PDB

4D75     E-value=1.89876e-60,     Score=590

KEGG

101739162    K15003 cytochrome P450 family 9 [EC:1.14.-.-] | (RefSeq) probable cytochrome P450 9f2

GO

GO:0004497   GO:0020037   GO:0016021   GO:0016705   GO:0005506   GO:0005789   GO:0035220   GO:0046872   GO:0007017   GO:0005200   GO:0003676   GO:0004812   GO:0006418   GO:0000049   GO:0016876   GO:0055114  

Subcellular location

Endoplasmic reticulum membrane  
Microsome membrane  

Length:

522

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

18.2527299999999

Exp number, first 60 AAs:

16.89295

Total prob of N-in:

0.80533

POSSIBLE N-term signal

sequence

inside

1  -  1

TMhelix

2  -  21

outside

22  -  522

 

 

Pi

371.610985

Theta

166.281894

Tajima's D

2.88029

CLR

0.744839

CSRT

0.971701414929254

Interpretation

Uncertain