Gene

KWMTBOMO09339

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr15(+):16534255-16535508      View in EpiBrowser

Full name

ATP-dependent DNA helicase      

Location in the cell

Cytoplasmic   Reliability : 1.705 Mitochondrial   Reliability : 1.605

CDS

ATGGAAGACGGGGCGCCACCCTGGGACCTGGAGGCGGAGGCGCTCGCTGCCGATTACCGGTGGCGTAGCGACCTTCGCTCTAGGGGGGAAGGGCGCCCCGGCGAAGGAGTAGTTCGAGCGCGGAGGCTCCAATCTCGGCGGTCCGTGCTGGAGGCGTGGTCTCGCCGCTTGGCGGACCCGTCGGCCGGCCTCCGTACCGTCGAGGCGGTCCGCCCGGTTCTCGCGGACTGGGTAGGCCGCGACCGCGGATGCCTCACCTTCCGGCTGACGCAAATGTTGACCGGCCATGGTTGTTTTGGCCGGTACTTGCACAAGATAGCCGGAAGGGAACCGACGGCGCAGTGCCACCACTGCGCGGACCGCGACGAGGATGACACAGCGGAACACACATTGGCGCGTTGCTCTGGTTTCGACGAGCAACGCGCCGCCCTCGTCGCGGTCATAGGAGAGGACCTCTCGCTGCCGCGCGTCGTGGCTACGATGCTCGGCAGCGACGCGTCCTGGAAGGCGATGCTCGACTTCTGCGAGTCCACCATCTCGCAGAAGGAGGCGGCGGAGCGAGAGGGAGAGCTCTTCCCTTTCCGCACCGATCCGTCGCCGTCGAGCCGGGGGCCGGAGGCAGGAATACGCCCGTACGTCCCGGCCCCTGTAGGTAGCGGCCTCCCCCCGGTGAAGGTCAAGGGGCGACCTGAGGGGGTGAGGCCGCGCGGCGCGCTACCAGCACTCTAG

Protein

MEDGAPPWDLEAEALAADYRWRSDLRSRGEGRPGEGVVRARRLQSRRSVLEAWSRRLADPSAGLRTVEAVRPVLADWVGRDRGCLTFRLTQMLTGHGCFGRYLHKIAGREPTAQCHHCADRDEDDTAEHTLARCSGFDEQRAALVAVIGEDLSLPRVVATMLGSDASWKAMLDFCESTISQKEAAEREGELFPFRTDPSPSSRGPEAGIRPYVPAPVGSGLPPVKVKGRPEGVRPRGALPAL

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Cofactor

FAD
Mg(2+)

Similarity

Belongs to the GMC oxidoreductase family.
Belongs to the helicase family.

Uniprot

Q5KTM7   Q868Q4   A0A2W1BDU5   A0A2W1B333   A0A0J7K2M2   A0A0J7KCI1   + More
A0A0J7N1D9   Q8MY27   A0A2W1BSQ5   A0A437BTM1   Q8MY33   Q8MY31   A0A2W1C3J5   A0A2W1BTM2   A0A0J7KJB9   Q8MY35   A0A3S2N998   A0A2H1WNZ5   A0A3S2NGT9   A0A0J7MZM4   A0A0J7N7H9   A0A2H1VYR8   A0A2H1W4U7   A0A437AS17   A0A0J7KS67   O01419   A0A0J7KQU9   A0A3L8D2G3   A0A3L8DDV9  

EC Number

3.6.4.12

Pubmed

12644555    28756777    9092665    30249741   

EMBL

AB126050    BAD86650.1    AB090825    BAC57926.1    KZ150308    PZC71477.1    + More
KZ150386    PZC71062.1    LBMM01016102    KMQ84557.1    LBMM01009501    KMQ88083.1    LBMM01012027    KMQ86470.1    AB078935    BAC06462.1    KZ149950    PZC76665.1    RSAL01000009    RVE53812.1    AB078930    BAC06454.1    AB078931    BAC06456.1    KZ149896    PZC78733.1    KZ149922    PZC77701.1    LBMM01006538    KMQ90523.1    AB078929    BAC06452.1    RSAL01000481    RVE41577.1    ODYU01009945    SOQ54696.1    RSAL01000109    RVE47213.1    LBMM01012957    LBMM01012956    KMQ85900.1    KMQ85901.1    LBMM01008861    KMQ88580.1    ODYU01005282    SOQ45985.1    ODYU01006342    SOQ48109.1    RSAL01001432    RVE40790.1    LBMM01003679    KMQ93242.1    D85594    BAA19776.1    LBMM01004152    KMQ92762.1    QOIP01000031    RLU14697.1    QOIP01000010    RLU18098.1   

Proteomes

UP000036403    UP000283053    UP000279307   

PRIDE

Q5KTM7    Q868Q4    O01419   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF01553   Acyltransferase
PF07776   zf-AD
PF00096   zf-C2H2
PF00732   GMC_oxred_N
PF05970   PIF1
PF00059   Lectin_C
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR036691   Endo/exonu/phosph_ase_sf       
IPR005135   Endo/exonuclease/phosphatase       
IPR002123   Plipid/glycerol_acylTrfase       
IPR012934   Znf_AD       
IPR013087   Znf_C2H2_type       
IPR036236   Znf_C2H2_sf       
IPR036188   FAD/NAD-bd_sf       
IPR012132   GMC_OxRdtase       
IPR000172   GMC_OxRdtase_N       
IPR016187   CTDL_fold       
IPR010285   DNA_helicase_pif1-like       
IPR016186   C-type_lectin-like/link_sf       
IPR001304   C-type_lectin-like       
IPR018378   C-type_lectin_CS       
IPR027417   P-loop_NTPase       

SUPFAM

SSF56219   SSF56219        + More
SSF57667   SSF57667       
SSF51905   SSF51905       
SSF52540   SSF52540       
SSF56436   SSF56436       

Gene 3D

3.60.10.10     3.50.50.60     3.10.100.10    

ProteinModelPortal

Q5KTM7   Q868Q4   A0A2W1BDU5   A0A2W1B333   A0A0J7K2M2   A0A0J7KCI1   + More
A0A0J7N1D9   Q8MY27   A0A2W1BSQ5   A0A437BTM1   Q8MY33   Q8MY31   A0A2W1C3J5   A0A2W1BTM2   A0A0J7KJB9   Q8MY35   A0A3S2N998   A0A2H1WNZ5   A0A3S2NGT9   A0A0J7MZM4   A0A0J7N7H9   A0A2H1VYR8   A0A2H1W4U7   A0A437AS17   A0A0J7KS67   O01419   A0A0J7KQU9   A0A3L8D2G3   A0A3L8DDV9  

PDB

4XVM     E-value=0.0555576,     Score=82

KEGG

101743871    no KO assigned | (RefSeq) uncharacterized LOC101743871

GO

GO:0003964   GO:0016746   GO:0016021   GO:0050660   GO:0016614  

Length:

242

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00198

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01004

outside

1  -  242

 

 

Pi

59.630572

Theta

39.068785

Tajima's D

1.231666

CLR

1.049358

CSRT

0.723413829308535

Interpretation

Uncertain