Gene

KWMTBOMO09326

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr15(+):16063455-16068286      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.62

CDS

ATGGAGGAAAAACTTTTCATCGACTTCATTCGGGAAAAATATCCGTCAATCGCGCCCGAATTCGAAGCCTATAGGGCCTCATTTGGTAATTATTCTCCCCCCGCATCTCTCGCCGCCGTCGCCAAACATGCCTCGCAGGCATGCCTCGCGTGCCCCGCCGCCGGTCCGTGTTCAAGCGCACGTACGCACGCCGCCGCCGTAGCGTCTAACGCCCCCGCCCCCGCTACCCCCGCGCCCGCGTCAATCACGTCAGTTTCGTCCGTCGCGACCTCAATAGCGTCTAGTTCAGGCTCCGATACCGAATCGGAGATGGACTTCGAGTCCGCGACTAGCCCTCAACCCGGAACCTCGGATGGGTTCCAAACTGTAACGCGCGGTAAAAAGCGTACTCGCGTCGTGGAGTCCCGGAGCTCCATGACGAAGCAAACCAAGTCCGCGACCGCCTCCCGACCGCAGGTAGTCGTAACGCCGGAGTCGGACTCCGCCCGCCGCGTAATCCCACCGCCGCGCCCAAAAACCGCGCCCGCGCCTAAAACAGTTGTCCCGCCCCCGCTGATACTCCAGGAGAAGTCAGCGTGGAATCGCGTATCCCAGGCCCTTCAGGCCAACAAAATTAATTATACCCATGCGCGTAACGTCGCGCATGGGATTCAGATTAAGGTCGCAACGCCGGGCGACCATAGGGCCCTCTCTGCTTACCTCCGAAAGGAGAACATAGGTTATCACACCTATGCTCTTCAGGAGGACCGCGAACTCCGCGTAGTGATACGTGGAGTCCCCAAGGAACTCGACATAGACTACGTAAAGGAGGATCTGATCGCATTCTACAATGCTAACGGACTCGCGCGGCAACGCGATCAAATTTTCGAATTCCTCCGCGATAATCTTGTAGATATTTTGTTAGTGCAGGAGACCTGTCTGAAGCCCTCGCGTCGTGACCCGAAAGTCGCGAATTACGTCATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGACTGCCATTTACTATAGGCGGGCTCTGCACGTTGTTCCTCTCGATACTCCCTCGCTCTTACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTCCTGAGCAGTGACATCGAGTCACTGTTTGGCATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGTACGAACTTTAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTCACTTTTGAAGTAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCATTGCTTAGGAACGTAACTCTGCGCTTACGTTCCATCGAAGCACTGTCAGAGCTCGACTCAGACCACCGACCTGTCGTTATGCAGCTCGGTCGCCCTCACAACCCAGCCACTGTTACGAGGACCATGGTGGATTGGAATAAGCTGGGCACGTGCCTAGCCGAAGCCGCTCCGCCAATCCTCCCTTACGGCCCGGATTCGAATCTATCCCCCGAGGACACCGTCGAATCCATAAACATCATTACTGATCACATCTCTTCCGCGATCATTAGATCTTCAAAAGAAGTCGATGTGGAGGACAGCTTCCACCGCATCAGACTGTCCTCCGAACTTAGGAATCTCTTAAGAGTTAGGAACGCGGCAATCCGGGCCTACGATCGTCTTCCCACGCATTCAAACCGGATTCGGATGCGTCGTCTACAACGCGAAGTCCACTCCCGCCTAAGTGACGCGCGTAACGATAATTGGCATAGTTATTTAGAACAACTCGCGCCCTCCCACCAAGCATACTGGCGACTAGCTAGGACTCTCAAATCCGAAACTACCGCTACTATGCCTCCCCTCGTACGCCCTTCAGGCCAACCACCGGCATTCGATGACGATGACAAGGCTGAGCTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACTGACGAAGTTAGAGACGCGATCCACAACCTCCAACCTAGGAAGGTACCCGGCTCCGACGGCATCCGCAACCGCGCGCTAAAACTCTTGCCAGTCCAACTGATAGCAATGTTGGCTACAATTTTAAATGCCGCTATGACGCACTGCATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGTATACATAAGCCGGGCAAACCGACAAACGAAACTTCTAGTTACCGTCCGATTAGTCTCCTCCCGACGATAGGAAAAATTTACGAACGGCTCCTTAGGAAACGCCTCTGGGATTTTGTTACCGCGAACAAAATTCTCATAGACGAACAGTTCGGATTCCGCTCTAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATCCTGATAGGACTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGACATCGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTAATTTACAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCAACTGACTGCCGGAGTCCCGCAAGGCTCCGCGCTCTCCCCGTTATTATTTAGTTTGTATATCAATGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGCTGCTTCATCGGCGACTCCAGATCGCAGTAGCCACCATGGGACAGTGGTTCCGGAAGTGGCGCATCGACATCAACCCCACGAAAAGCACAGCGGTGCTCTTCAAAAGGGGTCGCCCTCCGAATACCACTTCGAGCATCCCACTCCCTAATAGGCGCGCAAACACCTCCGCCGTTAGCCCCGTCACTCTCTTTGGCCAGCCCATACCGTGGGCCTCGCAGGTCAAATACCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGTCCCCATATTAAAACGGTACGCGACCGTGCCGCCTTCATATTAGGACGTCTCTACCCTATGCTTTGCAAGCGAAGCAAACTGTCCCTCCGTAATAAGGTAACTCTCTACAAAACTTGCATACGCCCCGTCATGACGTATGCAAGCGTAGTGTTCGCTCACGCAGCCCGCACCAACTTGAAGCCCCTTCAGGTTATTCAATCCCGATTCTGCAGGATAGCCGTCGGAGCACCATGGTTCCTGAGGAACGTGGATCTCCACGATGACCTGGAGCTTGACTCTGTCAGTAAGTATCTACAGTCGGCATCGCTGCGCCATTTTGAGAAGGCGGCACGACATGAGAACCCTCTCATCGTAGCCGCTGGAAATTACATACCCGACCCAGTAGACCGAATGGTAAACCGTCGACGTCGCCCAAAGCACGTCATTACGGATCCTCCTGATCCATTAAGGGTGCTCTTAGGCACCACAAGCACCGGTCACCGTCCTCGTCGAACCCGTCGCTTGCGACGAAGGGCTCGACGAGCGAACTAA

Protein

MEEKLFIDFIREKYPSIAPEFEAYRASFGNYSPPASLAAVAKHASQACLACPAAGPCSSARTHAAAVASNAPAPATPAPASITSVSSVATSIASSSGSDTESEMDFESATSPQPGTSDGFQTVTRGKKRTRVVESRSSMTKQTKSATASRPQVVVTPESDSARRVIPPPRPKTAPAPKTVVPPPLILQEKSAWNRVSQALQANKINYTHARNVAHGIQIKVATPGDHRALSAYLRKENIGYHTYALQEDRELRVVIRGVPKELDIDYVKEDLIAFYNANGLARQRDQIFEFLRDNLVDILLVQETCLKPSRRDPKVANYVMVRNDRLTASKGGTAIYYRRALHVVPLDTPSLLHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHRTNFNGRRLDAFIDDLTFEVVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEALSELDSDHRPVVMQLGRPHNPATVTRTMVDWNKLGTCLAEAAPPILPYGPDSNLSPEDTVESINIITDHISSAIIRSSKEVDVEDSFHRIRLSSELRNLLRVRNAAIRAYDRLPTHSNRIRMRRLQREVHSRLSDARNDNWHSYLEQLAPSHQAYWRLARTLKSETTATMPPLVRPSGQPPAFDDDDKAELLADALQEQCTTSTQHADPEHTELVDREVERRASLPPSDALPPITTDEVRDAIHNLQPRKVPGSDGIRNRALKLLPVQLIAMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPTNETSSYRPISLLPTIGKIYERLLRKRLWDFVTANKILIDEQFGFRSKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFLSNRSFRYRVEGTRSRPRQLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQIAVATMGQWFRKWRIDINPTKSTAVLFKRGRPPNTTSSIPLPNRRANTSAVSPVTLFGQPIPWASQVKYLGVTLDRGMTFRPHIKTVRDRAAFILGRLYPMLCKRSKLSLRNKVTLYKTCIRPVMTYASVVFAHAARTNLKPLQVIQSRFCRIAVGAPWFLRNVDLHDDLELDSVSKYLQSASLRHFEKAARHENPLIVAAGNYIPDPVDRMVNRRRRPKHVITDPPDPLRVLLGTTSTGHRPRRTRRLRRRARRAN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A2S2PPK8   A0A2S2Q383   X1WLB2   A0A023EZE6   Q07995   A0A3N5Z7I3   A0A224X6Q4   A0A2S2QEE0   A0A2M4BD66   A0A2J7R7D0   A0A087UGF5   A0A2M4BDA5   A0A2M4BD62   A0A2M4CV42   A0A2J7QR37   X1WNI2   A0A2M4CV52   A0A2J7QY69   A0A2J7PBY3   A0A2J7PU96   A0A2S2NGV8   A0A2M4BD67   A0A224XB44   A0A2M4BDV6   A0A224X6T4   A0A224X6S1   X1WQI9   A0A2S2N814   A0A2J7Q6J2   X1WZH0   A0A2J7PDM0   A0A2H8TF37   A0A224XI99   J9LFC9   A0A224X6U5   A0A2J7QB68   A0A069DZL8   A0A2S2P698   A0A2S2R9D4   A0A224X6R6   A0A1Y1KFR3   A0A087UCW3   P21328   A0A0A9YJ00   A0A224X746   A0A2J7PVX3   A0A0A9YU04   A0A1B6EGD8   A0A2A4IUM2   A0A069DX78   A0A2S2PJG2   A0A224XHW8   A0A224XJI0   A0A142LX26   K7IN67   A0A2S2NPG3   A0A2M4CVF1   A0A2M4CVK2   Q95SX7   A0A224X6W2   A0A0V0G5B6   P21329   A0A352X8G4   A0A2H8TKI9   A0A2J7Q0S7   A0A2S2PHL7   A0A2S2N6Q7   A0A2J7RD70   Q24335   A0A224XIB0   A0A2S2P7B2  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    8387152    30086797    26334808    2463954    3040362    1714378    25401762    25527032    20075255    7753626    12537569    1701254    30148503    2441397   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    GGMS01002992    MBY72195.1    ABLF02042518    ABLF02057746    GBBI01004571    JAC14141.1    S59870    AAB26437.2    RPOV01000134    RPJ78669.1    GFTR01008279    JAW08147.1    GGMS01006359    MBY75562.1    GGFJ01001844    MBW50985.1    NEVH01006736    PNF36716.1    KK119692    KFM76444.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GGFL01005012    MBW69190.1    NEVH01011985    PNF31054.1    ABLF02008153    ABLF02008462    ABLF02008464    GGFL01004957    MBW69135.1    NEVH01009134    PNF33528.1    NEVH01027074    PNF13841.1    NEVH01021205    PNF19912.1    GGMR01003407    MBY16026.1    GGFJ01001858    MBW50999.1    GFTR01008262    JAW08164.1    GGFJ01001857    MBW50998.1    GFTR01008261    JAW08165.1    GFTR01008271    JAW08155.1    ABLF02022418    GGMR01000676    MBY13295.1    NEVH01017470    PNF24199.1    ABLF02034467    NEVH01026386    PNF14434.1    GFXV01000908    MBW12713.1    GFTR01008256    JAW08170.1    ABLF02023911    GFTR01008251    JAW08175.1    NEVH01016302    PNF25823.1    GBGD01000415    JAC88474.1    GGMR01012305    MBY24924.1    GGMS01017365    MBY86568.1    GFTR01008269    JAW08157.1    GEZM01084969    JAV60363.1    KK119261    KFM75202.1    M22874    M38643    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GFTR01008151    JAW08275.1    NEVH01020940    PNF20481.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GEDC01000337    JAS36961.1    NWSH01007753    PCG62823.1    GBGD01000389    JAC88500.1    GGMR01016905    MBY29524.1    GFTR01008254    JAW08172.1    GFTR01008257    JAW08169.1    KU543673    AMS38352.1    GGMR01006408    MBY19027.1    GGFL01005122    MBW69300.1    GGFL01005121    MBW69299.1    AY060438    AAL25477.1    GFTR01008260    JAW08166.1    GECL01003538    JAP02586.1    M38437    DNOY01000259    HBE18313.1    GFXV01002840    MBW14645.1    NEVH01019963    PNF22185.1    GGMR01016296    MBY28915.1    GGMR01000226    MBY12845.1    NEVH01005295    PNF38784.1    M17214    AAA28508.1    GFTR01008246    JAW08180.1    GGMR01012676    MBY25295.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000218220    + More
UP000002358   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    P21328    Q95SX7    P21329    + More
Q24335   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A2S2PPK8   A0A2S2Q383   X1WLB2   A0A023EZE6   Q07995   A0A3N5Z7I3   A0A224X6Q4   A0A2S2QEE0   A0A2M4BD66   A0A2J7R7D0   A0A087UGF5   A0A2M4BDA5   A0A2M4BD62   A0A2M4CV42   A0A2J7QR37   X1WNI2   A0A2M4CV52   A0A2J7QY69   A0A2J7PBY3   A0A2J7PU96   A0A2S2NGV8   A0A2M4BD67   A0A224XB44   A0A2M4BDV6   A0A224X6T4   A0A224X6S1   X1WQI9   A0A2S2N814   A0A2J7Q6J2   X1WZH0   A0A2J7PDM0   A0A2H8TF37   A0A224XI99   J9LFC9   A0A224X6U5   A0A2J7QB68   A0A069DZL8   A0A2S2P698   A0A2S2R9D4   A0A224X6R6   A0A1Y1KFR3   A0A087UCW3   P21328   A0A0A9YJ00   A0A224X746   A0A2J7PVX3   A0A0A9YU04   A0A1B6EGD8   A0A2A4IUM2   A0A069DX78   A0A2S2PJG2   A0A224XHW8   A0A224XJI0   A0A142LX26   K7IN67   A0A2S2NPG3   A0A2M4CVF1   A0A2M4CVK2   Q95SX7   A0A224X6W2   A0A0V0G5B6   P21329   A0A352X8G4   A0A2H8TKI9   A0A2J7Q0S7   A0A2S2PHL7   A0A2S2N6Q7   A0A2J7RD70   Q24335   A0A224XIB0   A0A2S2P7B2  

PDB

6AR3     E-value=0.005008,     Score=99

KEGG

105842112    no KO assigned | (RefSeq) actin cytoskeleton-regulatory complex protein pan1-like

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1219

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.598419999999997

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.00004

outside

1  -  1219

 

 

Pi

102.852943

Theta

10.314079

Tajima's D

0

CLR

569.224511

CSRT

0.377731113444328

Interpretation

Uncertain