Gene

KWMTBOMO09311  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003439

Annotation

PREDICTED:_probable_pseudouridine-5'-phosphatase_[Amyelois_transitella]

Location

Bomo_Chr15(+):15747515-15751025      View in EpiBrowser

Full name

Probable pseudouridine-5'-phosphatase      

Alternative Name

GS1-like protein
Pseudouridine-5'-monophosphatase

Location in the cell

Cytoplasmic   Reliability : 1.651 Mitochondrial   Reliability : 1.648

CDS

ATGAGGTTTAATTTATTGAGAATAGTAAGAACGGTTCCTAAAGCTGTTGGCGCGCGATGCTACTCGACGAATAATTTTAAGACCGTCACCCACTGTATATTTGATATGGACGGTTTGTTATTAGACACCGAGCAAGTTTACAAAAAAATGATAACGCAACTTTGTGCGCAATATGGCCACACATACACCAATGAGCTCATGATGAAGATCTTGGGTGGTACAGAGCAACGACTCTCTGAAATCCTCTGTAAAGAACTGAACTTACCAGTGACTCCTACAGAATTTAGAGATCAATTACTTGTCTTAGGGGATAAGATGCTGGCTGGTACACCCTTATTAGATGGTGCAGAAAAACTAATAAGGCATTTACATAAAACAAAAGTACCGTTCGCGCTAGCCACGTCATCAAGTGAACGATCAGTGAAGACTAAAGTTGCTGCACATAAGGAGCTCTTCCAACTTTTCCACCACATGGTCATGGGAAGTTCTGATAAGGAGGTGAAATTTGGGAAACCACATCCTGATATATTCCTTGTGGCAGCCAATAGATTCCCAGACAAACCTGAACCTTCAAAGTGCCTTGTGTTTGAAGATTCCCCGCATGGCGTCACAGCAGGAATAAAAGCTGGCATGCAAGTAGTTATGGTACCCGACCCACACACAGACAAGAGACTGACTAAACACGCCACAGTAGTGTTACCAACTTTAGCAAAGTTCCAACCAGAGTGGTTTGGGTTACCAGCTTATTAA

Protein

MRFNLLRIVRTVPKAVGARCYSTNNFKTVTHCIFDMDGLLLDTEQVYKKMITQLCAQYGHTYTNELMMKILGGTEQRLSEILCKELNLPVTPTEFRDQLLVLGDKMLAGTPLLDGAEKLIRHLHKTKVPFALATSSSERSVKTKVAAHKELFQLFHHMVMGSSDKEVKFGKPHPDIFLVAANRFPDKPEPSKCLVFEDSPHGVTAGIKAGMQVVMVPDPHTDKRLTKHATVVLPTLAKFQPEWFGLPAY

Description

Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation.

Catalytic Activity

H2O + psi-UMP = phosphate + pseudouridine

Cofactor

Mg(2+)

Similarity

Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

Keywords

Complete proteome   Hydrolase   Magnesium   Metal-binding   Nucleotide metabolism   Reference proteome  

Feature

chain  Probable pseudouridine-5'-phosphatase

Uniprot

A0A194PJM2   A0A194RJ35   A0A2A4JLP6   A0A2H1VEM3   A0A0L7LLK6   A0A212F8Q0   + More
H9J1Q2   A0A2W1BVK3   A0A437BNW3   A0A1Q3FUU3   A0A2M4BXX4   A0A182XKA5   A0A453YJN7   F5HLS5   A0A2M4CTV4   A0A2M4ANA3   Q29LK4   U5EYP1   A0A067QTN3   A0A1L8DCY2   W8C406   A0A3B0K4J0   B4KEQ9   A0A453Z341   A0A2Y9D0Y1   A0T4G2   E2QCN9   A0A0K8VQ56   A0A0Q9WNL2   A0A0J9QVP5   Q17GH7   B4MTX6   A0A034WQP0   A0A0C9QTJ8   B4NKF8   A0A0K8TQY7   B4NYL0   A0A1I8MN88   B3N3S9   A0A2M4BY45   A0A0A1WKX4   A0A2M3Z4S4   W8BI78   E0VBZ4   A0A2M4ALP7   A0A1Y1NC04   A0A1W4WAF2   W5JCB8   A0A0M4EEI1   A0A2S2NEZ5   A0A0Q9X5P5   K7J4B2   A0A3B0JHT9   A0A182K1W3   B4LT64   B3MU26   A0A139WHD2   A0A084WT25   A0A182HCU5   A0A158NLD8   A0A0U1TYF2   A0A195CY64   A0A034WN03   A0A0C9RAW5   A0A0R3NZ21   A0A195E6Q3   A0A0K8U9E4   A0A034WRH8   A0A2P8XJF3   A0A182M1D9   A0A151IEQ1   A0A0A1WZY1   V5G133   A0A0Q9X0K5   A0A182RDE2   A0A182PCV0   A0A182W0N4   A0A151XCE6   A0A1W4W910   A0A182VFD8   C4WXI5   A0A336MMC7   H9JL36   A0A182TPL4   A0A182NSU3   T1E257   A0A1L8DAB4   A0A182FR97   Q94529   A0A1W4WI03   A0A0J9QVL7   A0A1B6DCE2   A0A1B6FTG0   A0A151X0K1   A0A182QUH8   A0A026WIG7   A0A0N0BIR5   A0A1Y1LCI7   A0A195AVH3   A0A158P248  

EC Number

3.1.3.96

Pubmed

26354079    26227816    22118469    19121390    28756777    12364791    + More
14747013    17210077    15632085    17994087    23185243    24845553    24495485    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    22936249    17510324    25348373    26369729    17550304    25315136    25830018    20566863    28004739    20920257    23761445    20075255    18057021    18362917    19820115    24438588    26483478    21347285    29403074    24330624    9055824    24508170    30249741   

EMBL

KQ459602    KPI93626.1    KQ460106    KPJ17838.1    NWSH01001155    PCG72330.1    + More
ODYU01002150    SOQ39275.1    JTDY01000685    KOB76229.1    AGBW02009685    OWR50114.1    BABH01024009    KZ149923    PZC77675.1    RSAL01000026    RVE52080.1    GFDL01003675    JAV31370.1    GGFJ01008794    MBW57935.1    APCN01002192    AAAB01008904    EGK97236.1    GGFL01004589    MBW68767.1    GGFK01008767    MBW42088.1    CH379060    EAL34041.3    KRT04422.1    GANO01001898    JAB57973.1    KK853286    KDR08959.1    GFDF01009904    JAV04180.1    GAMC01009876    JAB96679.1    OUUW01000004    SPP79871.1    CH933807    EDW12959.2    EAA44497.5    AE014134    AAN10348.2    GDHF01011619    JAI40695.1    CH940649    KRF81936.1    CM002910    KMY88081.1    CH477259    EAT45748.1    CH963852    EDW75565.2    GAKP01001998    JAC56954.1    GBYB01003997    JAG73764.1    CH964272    EDW84088.1    GDAI01001045    JAI16558.1    CM000157    EDW87643.2    CH954177    EDV57738.2    GGFJ01008792    MBW57933.1    GBXI01014603    JAC99688.1    GGFM01002768    MBW23519.1    GAMC01009877    JAB96678.1    DS235044    EEB10900.1    GGFK01008394    MBW41715.1    GEZM01012147    GEZM01012146    JAV93147.1    ADMH02001839    ETN60968.1    CP012523    ALC38555.1    GGMR01002697    MBY15316.1    KRG03519.1    AAZX01006389    SPP79872.1    EDW64906.2    KRF81935.1    CH902624    EDV33355.2    KQ971343    KYB27261.1    ATLV01026812    KE525419    KFB53369.1    JXUM01128127    JXUM01128128    KQ567279    KXJ69498.1    ADTU01019320    EU252355    ACD11926.1    KQ977115    KYN05610.1    GAKP01001996    JAC56956.1    GBYB01003996    JAG73763.1    KRT04420.1    KRT04421.1    KQ979568    KYN20771.1    GDHF01029334    JAI22980.1    GAKP01001995    JAC56957.1    PYGN01001923    PSN32125.1    AXCM01002171    KQ977858    KYM99286.1    GBXI01009668    JAD04624.1    GALX01004746    JAB63720.1    KRF98274.1    KQ982314    KYQ58023.1    ABLF02010290    AK342657    BAH72605.1    UFQT01001478    SSX30731.1    BABH01011545    GALA01001520    JAA93332.1    GFDF01010668    JAV03416.1    U66355    U66356    BT023759    KMY88082.1    KMY88083.1    GEDC01013960    JAS23338.1    GECZ01016340    GECZ01001079    JAS53429.1    JAS68690.1    KQ982625    KYQ53466.1    AXCN02000301    KK107185    QOIP01000012    EZA55810.1    RLU16311.1    KQ435726    KOX78131.1    GEZM01063155    JAV69266.1    KQ976731    KYM76233.1    ADTU01006978   

Proteomes

UP000053268    UP000053240    UP000218220    UP000037510    UP000007151    UP000005204    + More
UP000283053    UP000076407    UP000075840    UP000007062    UP000001819    UP000027135    UP000268350    UP000009192    UP000000803    UP000008792    UP000008820    UP000007798    UP000002282    UP000095301    UP000008711    UP000009046    UP000192221    UP000000673    UP000092553    UP000002358    UP000075881    UP000007801    UP000007266    UP000030765    UP000069940    UP000249989    UP000005205    UP000078542    UP000078492    UP000245037    UP000075883    UP000075900    UP000075885    UP000075920    UP000075809    UP000192223    UP000075903    UP000007819    UP000075902    UP000075884    UP000069272    UP000075886    UP000053097    UP000279307    UP000053105    UP000078540   

PRIDE

H9J1Q2    E2QCN9    H9JL36    Q94529   

Pfam

PF13419   HAD_2

Interpro

IPR041492   HAD_2        + More
IPR023214   HAD_sf       
IPR023198   PGP-like_dom2       
IPR036412   HAD-like_sf       
IPR006439   HAD-SF_hydro_IA       
IPR036875   Znf_CCHC_sf       

SUPFAM

SSF56784   SSF56784        + More
SSF57756   SSF57756       

Gene 3D

1.10.150.240     3.40.50.1000    

ProteinModelPortal

A0A194PJM2   A0A194RJ35   A0A2A4JLP6   A0A2H1VEM3   A0A0L7LLK6   A0A212F8Q0   + More
H9J1Q2   A0A2W1BVK3   A0A437BNW3   A0A1Q3FUU3   A0A2M4BXX4   A0A182XKA5   A0A453YJN7   F5HLS5   A0A2M4CTV4   A0A2M4ANA3   Q29LK4   U5EYP1   A0A067QTN3   A0A1L8DCY2   W8C406   A0A3B0K4J0   B4KEQ9   A0A453Z341   A0A2Y9D0Y1   A0T4G2   E2QCN9   A0A0K8VQ56   A0A0Q9WNL2   A0A0J9QVP5   Q17GH7   B4MTX6   A0A034WQP0   A0A0C9QTJ8   B4NKF8   A0A0K8TQY7   B4NYL0   A0A1I8MN88   B3N3S9   A0A2M4BY45   A0A0A1WKX4   A0A2M3Z4S4   W8BI78   E0VBZ4   A0A2M4ALP7   A0A1Y1NC04   A0A1W4WAF2   W5JCB8   A0A0M4EEI1   A0A2S2NEZ5   A0A0Q9X5P5   K7J4B2   A0A3B0JHT9   A0A182K1W3   B4LT64   B3MU26   A0A139WHD2   A0A084WT25   A0A182HCU5   A0A158NLD8   A0A0U1TYF2   A0A195CY64   A0A034WN03   A0A0C9RAW5   A0A0R3NZ21   A0A195E6Q3   A0A0K8U9E4   A0A034WRH8   A0A2P8XJF3   A0A182M1D9   A0A151IEQ1   A0A0A1WZY1   V5G133   A0A0Q9X0K5   A0A182RDE2   A0A182PCV0   A0A182W0N4   A0A151XCE6   A0A1W4W910   A0A182VFD8   C4WXI5   A0A336MMC7   H9JL36   A0A182TPL4   A0A182NSU3   T1E257   A0A1L8DAB4   A0A182FR97   Q94529   A0A1W4WI03   A0A0J9QVL7   A0A1B6DCE2   A0A1B6FTG0   A0A151X0K1   A0A182QUH8   A0A026WIG7   A0A0N0BIR5   A0A1Y1LCI7   A0A195AVH3   A0A158P248  

PDB

3L5K     E-value=6.76362e-52,     Score=513

KEGG

101738730    K17623 pseudouridine 5'-phosphatase [EC:3.1.3.96] | (RefSeq) probable pseudouridine-5'-phosphatase

GO

GO:0016787   GO:0000287   GO:0003676   GO:0008270   GO:0042060   GO:1990738   GO:0046872   GO:0009117   GO:0008152   GO:0043395   GO:0005634   GO:0032968   GO:0000166   GO:0016020   GO:0016876   GO:0043039  

Length:

249

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0021

Exp number, first 60 AAs:

0.00087

Total prob of N-in:

0.05442

outside

1  -  249

 

 

Pi

201.470723

Theta

154.108922

Tajima's D

1.066766

CLR

0.012671

CSRT

0.676166191690415

Interpretation

Uncertain