Gene

KWMTBOMO09300  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003309

Annotation

ribosomal_protein_P0_[Bombyx_mori]

Location

Bomo_Chr15(-):15448144-15451870      View in EpiBrowser

Full name

60S acidic ribosomal protein P0      

Alternative Name

Apurinic-apyrimidinic endonuclease
DNA-(apurinic or apyrimidinic site) lyase

Location in the cell

Cytoplasmic   Reliability : 2.335

CDS

ATGGGTAGGGAGGACAAGGCTACTTGGAAGTCTAACTACTTCGTTAAGATCATCCAACTCTTGGACGAGTACCCAAAATGTTTCATCGTGGGTGCCGATAACGTGGGCTCGCAACAGATGCAGCAGATCCGTATCTCGCTACGTGGCTCCAGTATCGTGCTCATGGGAAAAAACACAATGATGCGCAAAGCCATCAAAGACCACCTGGACAACAATCCAGCCCTCGAGAAACTGTTGCCACACATCAAGGGCAACGTTGGCTTCGTGTTCACCCGCGGAGACCTCGTTGAGGTCCGTGACAAACTGTTGGAGAACAAAGTCCAAGCTCCAGCTCGTCCTGGTGCCATTGCCCCATTGTCAGTCGTCATTCCCGCCCACAACACCGGCCTCGGTCCAGAGAAGACCTCTTTCTTCCAGGCTCTTTCTATCCCTACCAAGATTTCAAAGGGTACTATTGAAATCATCAACGATGTACACATCTTGAAGCCCGGTGACAAGGTTGGAGCTTCTGAAGCCACCCTTCTCAACATGTTGAACATCTCTCCATTCTCATATGGTCTTGTTGTTAAGCAGGTATATGATTCTGGAACTATTTTTGCACCTGAAATTCTGGACATCAAACCAGAAGATCTCCGTGCCAAGTTCCAAGCTGGAGTTGCTAATGTAGCTGCTCTTTCTTTGGCTATTGGTTACCCAACTATTGCTTCAGCCCCGCATTCCATTGCCAATGGTTTCAAGAACCTTTTGGCCATCGCTGCTGTCACAGAGGTTGAGTTTGAAGAAGCTACCACCATCAAGGAGTTCATTAAGGACCCATCAAAGTTCGCTGCAGTTGCTGCCGCGGTGGCACCGTCCGCCGCCGCTGCTCCGGCTGAGAAGAAGGAGGAAAAGAAAGAAGAAAAAGAGGAGGAAGAAAGCGATGACGACATGGGCTTTGGTCTCTTCGACTAG

Protein

MGREDKATWKSNYFVKIIQLLDEYPKCFIVGADNVGSQQMQQIRISLRGSSIVLMGKNTMMRKAIKDHLDNNPALEKLLPHIKGNVGFVFTRGDLVEVRDKLLENKVQAPARPGAIAPLSVVIPAHNTGLGPEKTSFFQALSIPTKISKGTIEIINDVHILKPGDKVGASEATLLNMLNISPFSYGLVVKQVYDSGTIFAPEILDIKPEDLRAKFQAGVANVAALSLAIGYPTIASAPHSIANGFKNLLAIAAVTEVEFEEATTIKEFIKDPSKFAAVAAAVAPSAAAAPAEKKEEKKEEKEEEESDDDMGFGLFD

Description

Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

Catalytic Activity

The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

Subunit

P0 forms a pentameric complex by interaction with dimers of P1 and P2.

Similarity

Belongs to the universal ribosomal protein uL10 family.

Keywords

Phosphoprotein   Ribonucleoprotein   Ribosomal protein   Complete proteome   Cytoplasm   DNA damage   DNA repair   Lyase   Nucleus   Reference proteome  

Feature

chain  60S acidic ribosomal protein P0

Uniprot

Q70YZ3   Q5UAU1   A0A212FEQ6   G0ZEC4   E7DZ05   I4DID8   + More
A0A194RK76   A0A2A4J9D4   A0A0K8SL83   A0A0L7LDY8   D1LYK0   I4DLY9   A0A3G1T1B4   Q8WQJ2   A0A3S2LR49   A0A222AJ53   A0A185RX45   E2BW93   D6WMT4   E2BWC5   A0A348G679   A0A0N0BIW7   Q6EV08   K7IQV7   E9II14   E2AZT8   A0A0C9RCN3   I6P504   V5GRW6   A0A2A3E478   V9IFN9   A0A087ZPA5   A0A0K8TQM2   I6P155   I6P6U6   A0A411G6P8   E6ZCJ9   A0A154NZP4   A0A026VZT8   A0A1B2M4Y0   Q6EV09   A0A0J7KN60   F4X3G3   A0A195BNB3   A0A195FCE2   A0A158NKQ4   A0A151X8W5   B0WQZ4   A0A1Q3FEK8   A0A195CJ37   J3JU33   Q1HR99   A0A195DHA1   J3JV87   A0A023EQJ9   A0A182Q7D3   A0A146LPN5   A0A182LZB4   A0A182K8J7   A0A182RZI1   A0A2M3YX70   A0A182FNS5   A0A2M3YXC4   A0A2M4BUA9   A0A182IRR4   A0A1Y1LK51   A0A2M3ZZC9   W5JMB2   A0A1Y9IV09   A0A0A1WZ39   Q8MQT0   A0A1B0D3Y1   B3MAK8   A0A182KXJ9   A0A182U5N4   A0A182HZC3   A0A182V7K1   A0A182WVR6   Q7PQG7   A0A336MDC9   A0A034VBX9   A0A067R8K2   B4IXN3   A0A109NIB3   W8CB96   Q9U3U0   Q9NHP0   Q29DM5   A0A182N4R2   A0A3B0JLU0   A0A0K8UBE5   A0A1W4VAZ1   M9PG76   P19889   B3NJ27   A0A1A9UP79   B4QKR0   B4IAY7   U5EVH7   A0A0J9RZV4  

Pubmed

14527730    19121390    22118469    22651552    26354079    26227816    + More
14668217    20798317    18362917    19820115    20075255    21282665    23569222    26369729    24508170    30249741    21719571    21347285    22516182    23537049    17204158    17510324    24945155    26483478    26823975    28004739    20920257    23761445    25830018    12903741    17994087    20966253    12364791    14747013    17210077    25348373    24845553    24495485    10672071    11024299    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    2471063    12537569    1870984    8932386    18327897    22936249   

EMBL

AJ457827    CAD29995.1    BABH01023979    AY769267    AAV34809.1    AGBW02008909    + More
OWR52222.1    JF265002    AEL28833.1    HQ424708    ADT80652.1    AK401056    KQ459602    BAM17678.1    KPI93614.1    KQ460106    KPJ17829.1    NWSH01002527    PCG68070.1    GBRD01011753    JAG54071.1    JTDY01001598    KOB73421.1    GU084274    ACY95307.1    AK402307    BAM18929.1    MG846922    AXY94774.1    AY072284    ODYU01001255    AAL62465.1    SOQ37213.1    RSAL01000026    RVE52072.1    KY564020    ASO76399.1    KM229767    AKC05613.1    GL451103    EFN79997.1    KQ971341    EFA04511.1    EFN80029.1    FX985621    BBF97952.1    KQ435726    KOX78148.1    AJ783863    CAH04311.1    GL763324    EFZ19789.1    GL444277    EFN61067.1    GBYB01006060    JAG75827.1    JQ771366    AFD93397.1    GALX01004089    JAB64377.1    KZ288381    PBC26515.1    JR041657    AEY59487.1    GDAI01001408    JAI16195.1    JQ771358    AFD93389.1    JQ771367    AFD93398.1    MH365708    QBB01517.1    FN908680    CBM69268.1    KQ434786    KZC05146.1    KK107538    QOIP01000005    EZA49150.1    RLU23180.1    KX447597    AOA60264.1    AJ783862    CAH04310.1    LBMM01005253    KMQ91679.1    GL888613    EGI58991.1    KQ976439    KYM86708.1    KQ981693    KYN37872.1    ADTU01018960    KQ982409    KYQ56817.1    DS232047    EDS33081.1    GFDL01009055    JAV25990.1    KQ977649    KYN00740.1    APGK01051867    BT126745    KB741207    KB632327    AEE61707.1    ENN72907.1    ERL92523.1    DQ440195    CH477695    ABF18228.1    EAT37166.1    KQ980886    KYN11839.1    BT127154    AEE62116.1    JXUM01082821    GAPW01002729    KQ563338    JAC10869.1    KXJ74024.1    AXCN02000015    GDHC01008765    JAQ09864.1    AXCM01001019    GGFM01000110    MBW20861.1    GGFM01000150    MBW20901.1    GGFJ01007529    MBW56670.1    GEZM01053565    JAV74013.1    GGFK01000447    MBW33768.1    ADMH02001019    ETN64428.1    GBXI01010522    JAD03770.1    AY127558    AAM97779.1    AJVK01011094    CH902618    EDV41295.1    APCN01005540    AAAB01008888    EAA08855.2    UFQS01000821    UFQT01000410    UFQT01000821    SSX07034.1    SSX24038.1    GAKP01019889    JAC39063.1    KK852865    KDR14762.1    CH916366    EDV97495.1    KC507365    AHB12488.1    GAMC01000654    JAC05902.1    Y18444    AF220939    AAF31449.1    CH379070    EAL30389.1    OUUW01000002    SPP76390.1    GDHF01029382    GDHF01028350    JAI22932.1    JAI23964.1    AE014296    AGB94895.1    M25772    AY075528    BT021447    CH954178    EDV52744.1    CM000363    EDX11475.1    CH480826    EDW44450.1    GANO01001021    JAB58850.1    CM002912    KMZ01149.1   

Proteomes

UP000005204    UP000007151    UP000053268    UP000053240    UP000218220    UP000037510    + More
UP000283053    UP000008237    UP000007266    UP000053105    UP000002358    UP000000311    UP000242457    UP000005203    UP000076502    UP000053097    UP000279307    UP000036403    UP000007755    UP000078540    UP000078541    UP000005205    UP000075809    UP000002320    UP000078542    UP000019118    UP000030742    UP000008820    UP000078492    UP000069940    UP000249989    UP000075886    UP000075883    UP000075881    UP000075900    UP000069272    UP000075880    UP000000673    UP000075920    UP000092462    UP000007801    UP000075882    UP000075902    UP000075840    UP000075903    UP000076407    UP000007062    UP000027135    UP000001070    UP000001819    UP000075884    UP000268350    UP000192221    UP000000803    UP000008711    UP000078200    UP000000304    UP000001292   

PRIDE

Q70YZ3    Q5UAU1    A0A087ZPA5    Q9U3U0    M9PG76    P19889    + More

Pfam

PF17777   RL10P_insert        + More
PF00466   Ribosomal_L10

Interpro

IPR040637   RL10P_insert        + More
IPR030670   L10E_eukaryotes       
IPR001790   Ribosomal_L10P       

ProteinModelPortal

Q70YZ3   Q5UAU1   A0A212FEQ6   G0ZEC4   E7DZ05   I4DID8   + More
A0A194RK76   A0A2A4J9D4   A0A0K8SL83   A0A0L7LDY8   D1LYK0   I4DLY9   A0A3G1T1B4   Q8WQJ2   A0A3S2LR49   A0A222AJ53   A0A185RX45   E2BW93   D6WMT4   E2BWC5   A0A348G679   A0A0N0BIW7   Q6EV08   K7IQV7   E9II14   E2AZT8   A0A0C9RCN3   I6P504   V5GRW6   A0A2A3E478   V9IFN9   A0A087ZPA5   A0A0K8TQM2   I6P155   I6P6U6   A0A411G6P8   E6ZCJ9   A0A154NZP4   A0A026VZT8   A0A1B2M4Y0   Q6EV09   A0A0J7KN60   F4X3G3   A0A195BNB3   A0A195FCE2   A0A158NKQ4   A0A151X8W5   B0WQZ4   A0A1Q3FEK8   A0A195CJ37   J3JU33   Q1HR99   A0A195DHA1   J3JV87   A0A023EQJ9   A0A182Q7D3   A0A146LPN5   A0A182LZB4   A0A182K8J7   A0A182RZI1   A0A2M3YX70   A0A182FNS5   A0A2M3YXC4   A0A2M4BUA9   A0A182IRR4   A0A1Y1LK51   A0A2M3ZZC9   W5JMB2   A0A1Y9IV09   A0A0A1WZ39   Q8MQT0   A0A1B0D3Y1   B3MAK8   A0A182KXJ9   A0A182U5N4   A0A182HZC3   A0A182V7K1   A0A182WVR6   Q7PQG7   A0A336MDC9   A0A034VBX9   A0A067R8K2   B4IXN3   A0A109NIB3   W8CB96   Q9U3U0   Q9NHP0   Q29DM5   A0A182N4R2   A0A3B0JLU0   A0A0K8UBE5   A0A1W4VAZ1   M9PG76   P19889   B3NJ27   A0A1A9UP79   B4QKR0   B4IAY7   U5EVH7   A0A0J9RZV4  

PDB

5AJ0     E-value=6.56176e-106,     Score=980

KEGG

692657    K02941 large subunit ribosomal protein LP0 | (RefSeq) RpP0, p0; ribosomal protein P0

PATHWAY

03010    Ribosome - Bombyx mori (domestic silkworm)

GO

GO:0005840   GO:0042254   GO:0022625   GO:0002181   GO:0070180   GO:0003735   GO:0000027   GO:0006284   GO:0005509   GO:0052720   GO:0016363   GO:0005829   GO:0005654   GO:0000287   GO:0090305   GO:0003906   GO:0004519   GO:0140078   GO:0022626   GO:0005622   GO:0008168   GO:0005515   GO:0003676   GO:0000166   GO:0046872   GO:0016020   GO:0016876   GO:0043039  

Subcellular location

Cytoplasm  
Nucleus  

Length:

316

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

4.6004

Exp number, first 60 AAs:

0.00785

Total prob of N-in:

0.27582

outside

1  -  316

 

 

Pi

14.404165

Theta

15.870635

Tajima's D

-0.593822

CLR

0.169589

CSRT

0.219589020548973

Interpretation

Uncertain