Gene

KWMTBOMO09279

Pre Gene Modal

BGIBMGA003424

Annotation

PREDICTED:_FERM?_RhoGEF_and_pleckstrin_domain-containing_protein_1-like_isoform_X4_[Bombyx_mori]

Location

Bomo_Chr15(+):15013455-15045201      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 2.63

CDS

ATGATGGACTCAGAACTACCACCGGGAAGCTGCAATTCCACTGGACATCTGTCCACAATAGGATATCACACCTTGCCTGGCCGCATGCACCATTCGGCCAGTACACCGGCCGGTGTGGATGGCGCAGGCGGGGGCTCCAGGACGCCCCCCGCGACCCCCAAGAAGGGCGGCAAGATGCTCGCGGTCAGAGTTCAGATGCTAGATGACACTATATCAATGTTTCAAATACAGTCTAAAGCCCTTGGTCGAGTGCTGTTTGATCAAGTTTGCCGACAGCTACATCTCCTGGAAGCTGACTACTTTGGGCTTGAATATCAGGACAGCAATGGAACTAAGTACTGGCTGGACGTCGAGAAGCCGATGTGTCGGCAAGTCGGCCTGTCCATGCTGGAGCCCACGCTGCGTTTCTGCGTCAAGTTCTACACACCGGACCCGGCGAGGCTGGAGGAGGAGTTCACGCGGTACCTGTTCTGTTTGCAAGTGAAGCGCGACCTGGCCCAGGGCTGTATACAGTGCAACGAGAACACGGCCGCCCTGATGGCCAGTTACATCGTTCAAGCCGAATGCGGCGACTTCGTCCCGGAGGATTATCCGGACCACACCTACCTGAGCGGCTACAAGTTCTTCCCGAGCCAAGACTCTGAATCAGAGCGCAGGATCATGGAGAACCACAAGAAACACATAGGTCAAAGTCCAGCTGAAGCCGATTTAAACCTATTAGAGACGGCACGAAGATGCGAACTATACGGTATAAAGATTCACTCGACCAAAGATCACGAGGGCGTGCCGCTCAATCTGGCGGTTGCCCACATGGGCATCGTTGTGTTCCAGAACTACACGAAGATAAATACGTTCAGCTGGGCCAAGATAAGGAAGATATCGTTCAAGAGGAAAAAGTTCCTGATCAAACTCCACCCTGAAGGCTACGGATATTACCGAGACGTGGTCGAGTTCTTTTTCGAAGGTCGGAACGAGTGCAAGAACTTCTGGAAGAAATGCGTCGAGAACCACGGCTTCTTCCGGTGCTCCAGCGTGCCGCGCCTGCCGCGACACAAGACCAGGGTCATCTCGCGCGGCTCCTCCTTCAGGTACAGCGGCAAAACCCAGAAACAGATAGTCGAATTCGTTCGCGACAACTACGTGAAACGACAAACGTTCCAAAGGTCGGGCTCGTTCCGCGCGACCCGAGTGGCTAGCGGCGCGCTGCCCTCCAGCCTCTCCGCGCACCCGCTGCTGCCGCTGCCGCCCGGCTCCGACGCGATTTCCCTGGAGTGGGACAAGCAGCCTCACTACCTGGAGGCTTCTCTGATGATGAAGGGATACTCGGCGGAGGAGGCGCGGGCGGCGGCCGAACGGGCTCGGTGTCGGCCTCCCGCCGTTCGCCCACCGCTACAAGCTACCGCCTATGTCAACACGAGGGACAAGCTGACAAAACAATACTGCAGCCAAATAGTAAGAGGCTTTCACAATTGGCTTTTTAACTTGTATATCGATGTTTTACGTTCATCCCTAACATGA

Protein

MMDSELPPGSCNSTGHLSTIGYHTLPGRMHHSASTPAGVDGAGGGSRTPPATPKKGGKMLAVRVQMLDDTISMFQIQSKALGRVLFDQVCRQLHLLEADYFGLEYQDSNGTKYWLDVEKPMCRQVGLSMLEPTLRFCVKFYTPDPARLEEEFTRYLFCLQVKRDLAQGCIQCNENTAALMASYIVQAECGDFVPEDYPDHTYLSGYKFFPSQDSESERRIMENHKKHIGQSPAEADLNLLETARRCELYGIKIHSTKDHEGVPLNLAVAHMGIVVFQNYTKINTFSWAKIRKISFKRKKFLIKLHPEGYGYYRDVVEFFFEGRNECKNFWKKCVENHGFFRCSSVPRLPRHKTRVISRGSSFRYSGKTQKQIVEFVRDNYVKRQTFQRSGSFRATRVASGALPSSLSAHPLLPLPPGSDAISLEWDKQPHYLEASLMMKGYSAEEARAAAERARCRPPAVRPPLQATAYVNTRDKLTKQYCSQIVRGFHNWLFNLYIDVLRSSLT

Uniprot

A0A437BNU6   A0A194PLJ1   A0A2W1BVH1   A0A212ENH7   A0A154PTV5   A0A158NTJ5   + More
F4WQV9   D6WK31   A0A0N0U7E0   E2BXI1   E2A9L5   A0A194RJT4   A0A087ZW75   A0A195EF61   A0A232EXP7   A0A151X3B0   A0A0C9RSH8   A0A195BQ22   A0A2A3EN60   A0A195ESS5   A0A2J7QL82   A0A2J7QL78   A0A1Y1K547   A0A151IEJ2   A0A067RE36   A0A0J7KUV1   A0A3L8DLZ7   A0A1Y1K4B0   A0A1B6KVY3   A0A1B6G4V9   A0A1B6CJ10   A8JQT5   B3M146   A0A1B6DJP3   A0A0R1E5N5   B4PUI6   A0A1W4UWJ6   B4KDC3   B4M543   U4UHL3   A0A0Q9X4I4   B5DY72   N6TBT6   N6U9C1   E0VC18   B4GFH6   A0A336LTR5   Q2M1E6   A0A034W272   A0A0P8Y1V5   A0A0K8UX64   A0A0Q9WDP2   A0A3B0JQZ6   B5DY71   A0A0A1WSP4   A0A0Q9X152   A0A3B0JU46   A0A3B0JR29   U5EY02   B4NL67   B3P282   Q9VN68   A0A182YBF7   A0A1L8DM85   B4QW64   B4I3U6   A0A1L8DMG9   A0A026WLU6   A0A1S4G739   A0A182PRP8   A0A1Y9IUW5   A0A0C4DHA1   B4JSW0   A0A1W4UJK2   A0A1Q3FUZ1   A0A0R1E031   A0A182RVR0   A0A0R3NIS0   A0A0R3NMT0   A0A0R1E011   A0A0M4ECJ9   A0A182X9J1   A0A1S4GBL6   F5HMU0   A0A182HKH4   W5J8B1   A0A1I8QEW2   A0A1J1IE36   A0A084VXS3   J9JXV0   A0A1Y9IVA5   Q7PX94   A0A1S4GC55   A0A182K0H5   F5HMU1   A0A0L0CI94   A0A2M3Z156  

Pubmed

26354079    28756777    22118469    21347285    21719571    18362917    + More
19820115    20798317    28648823    28004739    24845553    30249741    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17994087    18057021    17550304    23537049    15632085    23185243    20566863    26109357    26109356    25348373    25830018    25244985    24508170    12364791    20920257    24438588    26108605   

EMBL

RSAL01000026    RVE52060.1    KQ459602    KPI93599.1    KZ149923    PZC77645.1    + More
AGBW02013658    OWR43029.1    KQ435127    KZC14788.1    ADTU01025977    GL888275    EGI63472.1    KQ971342    EFA03623.2    KQ435713    KOX79301.1    GL451254    EFN79629.1    GL437918    EFN69817.1    KQ460106    KPJ17812.1    KQ978983    KYN26796.1    NNAY01001722    OXU23125.1    KQ982562    KYQ54893.1    GBYB01011600    JAG81367.1    KQ976424    KYM88622.1    KZ288215    PBC32481.1    KQ981993    KYN30934.1    NEVH01013250    PNF29345.1    PNF29344.1    GEZM01096972    JAV54476.1    KQ977870    KYM99233.1    KK852751    KDR17143.1    LBMM01003033    KMQ94044.1    QOIP01000007    RLU20848.1    GEZM01096973    JAV54475.1    GEBQ01024389    GEBQ01020921    JAT15588.1    JAT19056.1    GECZ01015866    GECZ01012284    JAS53903.1    JAS57485.1    GEDC01030475    GEDC01023871    JAS06823.1    JAS13427.1    AE014297    ABW08601.2    CH902617    EDV44316.1    KPU80755.1    KPU80756.1    KPU80757.1    KPU80758.1    KPU80759.1    GEDC01030468    GEDC01012819    GEDC01011443    JAS06830.1    JAS24479.1    JAS25855.1    CM000160    KRK02647.1    EDW95708.2    KRK02649.1    KRK02650.1    KRK02652.1    KRK02653.1    CH933806    EDW15932.1    KRG01823.1    CH940652    EDW59754.1    KRF79050.1    KB632357    ERL93484.1    CH964272    KRG00002.1    CM000070    EDY68339.3    KRT00849.1    APGK01043804    APGK01043805    APGK01043806    KB741018    ENN75188.1    ENN75187.1    DS235044    EEB10924.1    CH479182    EDW34361.1    UFQT01000194    SSX21442.1    BT024186    ABC86248.1    ABI31137.1    GAKP01011064    JAC47888.1    KPU80760.1    GDHF01022354    GDHF01021359    JAI29960.1    JAI30955.1    KRF79051.1    OUUW01000008    SPP84584.1    EDY68338.2    GBXI01016620    GBXI01012849    GBXI01002325    JAC97671.1    JAD01443.1    JAD11967.1    KRG01824.1    SPP84583.1    SPP84585.1    GANO01000673    JAB59198.1    EDW84270.2    CH954181    EDV47832.1    AY060484    AAF52081.2    AAL25523.1    GFDF01006516    JAV07568.1    CM000364    EDX11663.1    CH480821    EDW54889.1    GFDF01006517    JAV07567.1    KK107152    EZA57020.1    AAF52080.3    CH916373    EDV94850.1    GFDL01003697    JAV31348.1    KRK02648.1    KRT00846.1    KRT00847.1    KRK02651.1    CP012526    ALC45391.1    AAAB01008987    EGK97612.1    APCN01000830    ADMH02002105    ETN59024.1    CVRI01000047    CRK98472.1    ATLV01018205    KE525224    KFB42767.1    ABLF02034860    EAA01206.5    EGK97613.1    JRES01000339    KNC32133.1    GGFM01001494    MBW22245.1   

Proteomes

UP000283053    UP000053268    UP000007151    UP000076502    UP000005205    UP000007755    + More
UP000007266    UP000053105    UP000008237    UP000000311    UP000053240    UP000005203    UP000078492    UP000215335    UP000075809    UP000078540    UP000242457    UP000078541    UP000235965    UP000078542    UP000027135    UP000036403    UP000279307    UP000000803    UP000007801    UP000002282    UP000192221    UP000009192    UP000008792    UP000030742    UP000007798    UP000001819    UP000019118    UP000009046    UP000008744    UP000268350    UP000008711    UP000076408    UP000000304    UP000001292    UP000053097    UP000075885    UP000075920    UP000001070    UP000075900    UP000092553    UP000076407    UP000007062    UP000075840    UP000000673    UP000095300    UP000183832    UP000030765    UP000007819    UP000075881    UP000037069   

PRIDE

A8JQT5    Q2M1E6    Q9VN68   

Pfam

PF00169   PH        + More
PF08736   FA
PF00621   RhoGEF
PF00373   FERM_M
PF09380   FERM_C
PF09379   FERM_N

Interpro

IPR035963   FERM_2        + More
IPR014847   FERM-adjacent       
IPR035899   DBL_dom_sf       
IPR019749   Band_41_domain       
IPR041788   FARP1/FARP2/FRMD7_FERM_C       
IPR014352   FERM/acyl-CoA-bd_prot_sf       
IPR000299   FERM_domain       
IPR029071   Ubiquitin-like_domsf       
IPR000219   DH-domain       
IPR001849   PH_domain       
IPR018980   FERM_PH-like_C       
IPR019748   FERM_central       
IPR000798   Ez/rad/moesin-like       
IPR011993   PH-like_dom_sf       
IPR018979   FERM_N       
IPR019747   FERM_CS       

SUPFAM

SSF47031   SSF47031        + More
SSF54236   SSF54236       
SSF48065   SSF48065       

Gene 3D

1.20.80.10     1.20.900.10     2.30.29.30    

CDD

cd14473  FERM_B-lobe
cd13193  FERM_C_FARP1-like
cd00160  RhoGEF

ProteinModelPortal

A0A437BNU6   A0A194PLJ1   A0A2W1BVH1   A0A212ENH7   A0A154PTV5   A0A158NTJ5   + More
F4WQV9   D6WK31   A0A0N0U7E0   E2BXI1   E2A9L5   A0A194RJT4   A0A087ZW75   A0A195EF61   A0A232EXP7   A0A151X3B0   A0A0C9RSH8   A0A195BQ22   A0A2A3EN60   A0A195ESS5   A0A2J7QL82   A0A2J7QL78   A0A1Y1K547   A0A151IEJ2   A0A067RE36   A0A0J7KUV1   A0A3L8DLZ7   A0A1Y1K4B0   A0A1B6KVY3   A0A1B6G4V9   A0A1B6CJ10   A8JQT5   B3M146   A0A1B6DJP3   A0A0R1E5N5   B4PUI6   A0A1W4UWJ6   B4KDC3   B4M543   U4UHL3   A0A0Q9X4I4   B5DY72   N6TBT6   N6U9C1   E0VC18   B4GFH6   A0A336LTR5   Q2M1E6   A0A034W272   A0A0P8Y1V5   A0A0K8UX64   A0A0Q9WDP2   A0A3B0JQZ6   B5DY71   A0A0A1WSP4   A0A0Q9X152   A0A3B0JU46   A0A3B0JR29   U5EY02   B4NL67   B3P282   Q9VN68   A0A182YBF7   A0A1L8DM85   B4QW64   B4I3U6   A0A1L8DMG9   A0A026WLU6   A0A1S4G739   A0A182PRP8   A0A1Y9IUW5   A0A0C4DHA1   B4JSW0   A0A1W4UJK2   A0A1Q3FUZ1   A0A0R1E031   A0A182RVR0   A0A0R3NIS0   A0A0R3NMT0   A0A0R1E011   A0A0M4ECJ9   A0A182X9J1   A0A1S4GBL6   F5HMU0   A0A182HKH4   W5J8B1   A0A1I8QEW2   A0A1J1IE36   A0A084VXS3   J9JXV0   A0A1Y9IVA5   Q7PX94   A0A1S4GC55   A0A182K0H5   F5HMU1   A0A0L0CI94   A0A2M3Z156  

PDB

6D21     E-value=4.99565e-88,     Score=828

KEGG

101736960    K06082 FERM, RhoGEF and pleckstrin domain protein 2 | (RefSeq) FERM, RhoGEF and pleckstrin domain-co

GO

GO:0005856   GO:0008092   GO:0030676   GO:0005089   GO:0035023   GO:0016601   GO:0005737   GO:0019898   GO:0016021   GO:0000166   GO:0046872   GO:0016020   GO:0016876   GO:0043039  

Length:

505

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0406400000000001

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.00039

outside

1  -  505

 

 

Pi

203.789428

Theta

167.35027

Tajima's D

0.95925

CLR

0.628726

CSRT

0.650017499125044

Interpretation

Uncertain