Gene

KWMTBOMO09274  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003319

Annotation

PREDICTED:_aspartate_aminotransferase?_cytoplasmic_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr15(-):14933300-14949494      View in EpiBrowser

Full name

Aspartate aminotransferase      

Location in the cell

Cytoplasmic   Reliability : 2.056

CDS

ATGGCTTCTCGATTCCAAGGTGTCGAACAAGGCCCCCCGATAGAGGTGTTTTTGTTAAACAGACTTTTTACTGAGGATACTTTTCAAAATAAAGTTAATTTAGGAGTTGGAGCATACAGAGATGAAAATGGAAAACCATGGGTACTGCCCATCGTTCGTAAGATGGAAAAACAGCTGGCAGCAGATGAAACCTTACTGCATGAATACCTTCCCGTGTTAGGTCTGGAGCAGTTTTGTAATGCGTCTGTGGCTATGCTCCTTGGTGAGGATAGTCCTGCCATCGCCGCTGGAAAAGCTTTCGGTGTGCAAGTCTTGTCCGGGACTGGTGGTCTGCGCGTCGGCGCCGAGTTCCTCAACAAGCATCTTAAATATGATACATTCTACTACTCCACACCTACATGGGAGAATCATCACCTAGTATTCGTGAACTCTGGTTTCACGAAGCCTCGCTCGTACCGCTACTGGGACCCGAAGACCAGGGGCATAGACTTCGACGGTTTCATCGAAGACCTCAAGAGCGCTCCGGAGAATGCCGTCATACTGCTGCACGCATGCGCCCACAATCCCACAGGCATAGACCCCACCAGGGAACAGTGGATGAAAATAGCTGATGTTATGGAGGAGCGCAAGTTGTTCCCGTTCTTCGACAGCGCGTACCAAGGGTTCGCGTCGGGCGACTTGGACGGAGACGCGTGGGCGGTGCGGTACTTCGTCAGTCGCGGCTTCGAACTCGTCTGCGCTCAGTCCTATGCCAAGAATTTCGGACTTTACAATGAACGCGTTGGCAACCTAGCGGTGGTATTGAACGAGTCTGCGCACGTTGCTCGCATAAAGTCCCAGATGACGTGGATCGTGCGAGGGATGTACTCCAACCCGCCAGCGCACGGGGCCCACGTCGTGGCCGCCGTGCTCACTAACAAGCAGCTCTTCGACGAGTGGAGGGACCACATCAAACTCATGTCTACGAGGGTCATGCAGATGAGAGAAGCTCTGAGGTCTGAGCTCGTGAAACTGGGAACTCCCGGCAACTGGGACCACATAGTGAAGCAGATTGGGCTATTCTCGTACACGGGTCTGAACCAGCGCCAGTGCGAGTACTTGATACAGGAGTACCACATCTATCTGCTGAAGTCCGGTCGCATCAACATCTGCGGGCTGAACCCGGGAAACGTGCAGTACGTGGCTAAAGCCATCAACGACGCGGTCACCAAGTTCCCTGACGATCACGACAATCGAGCGAAGTTATGA

Protein

MASRFQGVEQGPPIEVFLLNRLFTEDTFQNKVNLGVGAYRDENGKPWVLPIVRKMEKQLAADETLLHEYLPVLGLEQFCNASVAMLLGEDSPAIAAGKAFGVQVLSGTGGLRVGAEFLNKHLKYDTFYYSTPTWENHHLVFVNSGFTKPRSYRYWDPKTRGIDFDGFIEDLKSAPENAVILLHACAHNPTGIDPTREQWMKIADVMEERKLFPFFDSAYQGFASGDLDGDAWAVRYFVSRGFELVCAQSYAKNFGLYNERVGNLAVVLNESAHVARIKSQMTWIVRGMYSNPPAHGAHVVAAVLTNKQLFDEWRDHIKLMSTRVMQMREALRSELVKLGTPGNWDHIVKQIGLFSYTGLNQRQCEYLIQEYHIYLLKSGRINICGLNPGNVQYVAKAINDAVTKFPDDHDNRAKL

Catalytic Activity

2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate

Subunit

Homodimer.

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

Feature

chain  Aspartate aminotransferase

Uniprot

H9J1D2   A0A212ENG7   A0A2A4JUG9   A0A194PKR4   A0A2A4JUS7   S4P8E3   + More
A0A2W1B2Y8   A0A437BNU4   A0A286T886   A0A1B6LUX2   E2AD28   A0A232F6X6   K7J4Q5   A0A1I8MDM9   A0A0L7QQR4   A0A1L8EHE6   J3JZG8   A0A336ME91   A0A139WGX0   D6WLK0   A0A026VVN6   A0A1I8NTS8   F4WRA2   A0A1I8NTU3   B0WKE5   G3MNQ8   A0A423U3M3   A0A0J7NT78   A0A0L0CPL8   A0A1B6EGT9   E0VIU2   A0A1Y1LB57   E2BMX0   A0A0T6BEY3   A0A411G7V3   A0A154PH48   V5SI13   A0A023FW59   A0A087UAJ9   A0A1A9W3A5   A0A1Q3FJP1   Q5K6H4   A0A023ERN7   A0A023ESU6   A0A158NUA6   A0A182J070   A0A2M4AD35   A0A286T8E3   A0A182F9E4   A0A084VLB6   A0A1B0B6M6   A0A131XIE3   A0A182RYK7   A0A182MB16   Q16LN3   A0A182PPZ4   A0A1B0A700   A0A2M4BQ28   A0A1E1XHD6   W5JI36   A0A1L8E2F8   A0A182N5Q7   A0A1A9UIE9   A0A1L8DQY1   D3TRZ7   A0A182Q0R3   A0A3B0J1W3   A0A1D2MYX3   A0A182W1K6   A0A182U2L9   A0A182YGL0   A0A182UP30   A0A182L7F0   Q7QB79   L7M7N7   C1C1U3   A0A182XJ05   A0A067RE69   A0A182I7V0   A0A0K8RKI9   U5EW46   A0A2A3EF32   V9IKH9   A0A2R5L684   A0A293MQX8   A0A0P5K381   A0A0P5NY43   A0A0P5HRT9   A0A0P6AZD2   A0A0P5I1C1   A0A0P5J4N6   B5E189   B4H584   A0A0P5IAY4   A0A0P5RQV0   E9H8T5   V5G1F1   A0A0P5HV36   A0A0P6FG42   A0A0P5K316  

EC Number

2.6.1.1

Pubmed

19121390    22118469    26354079    23622113    28756777    20798317    + More
28648823    20075255    25315136    22516182    23537049    18362917    19820115    24508170    30249741    21719571    22216098    26108605    20566863    28004739    24945155    21347285    24438588    28049606    17510324    28503490    20920257    23761445    20353571    27289101    25244985    20966253    12364791    14747013    17210077    25576852    24845553    15632085    17994087    21292972   

EMBL

BABH01023934    AGBW02013658    OWR43034.1    NWSH01000596    PCG75449.1    KQ459602    + More
KPI93593.1    PCG75448.1    GAIX01004219    JAA88341.1    KZ150539    PZC70578.1    RSAL01000026    RVE52055.1    LC260175    BBA45746.1    GEBQ01012506    GEBQ01004393    JAT27471.1    JAT35584.1    GL438658    EFN68664.1    NNAY01000855    OXU26188.1    AAZX01008388    KQ414785    KOC60967.1    GFDG01000639    JAV18160.1    APGK01028345    BT128650    KB740686    KB631930    AEE63607.1    ENN79554.1    ERL87311.1    UFQT01000773    SSX27113.1    KQ971343    KYB27212.1    EFA04122.1    KK107796    QOIP01000013    EZA47715.1    RLU15567.1    GL888284    EGI63319.1    DS231971    EDS29765.1    JO843509    AEO35126.1    QCYY01000703    ROT83300.1    LBMM01001886    KMQ95610.1    JRES01000080    KNC34305.1    GEDC01000146    JAS37152.1    DS235206    EEB13298.1    GEZM01063258    JAV69165.1    GL449377    EFN82952.1    LJIG01001042    KRT85898.1    MH366205    QBB02014.1    KQ434902    KZC11179.1    KF647648    AHB50510.1    GBBL01001234    JAC26086.1    KK119009    KFM74388.1    GFDL01007248    JAV27797.1    AF395205    AAQ02891.1    GAPW01001728    JAC11870.1    GAPW01001727    JAC11871.1    ADTU01026372    GGFK01005372    MBW38693.1    LC260176    BBA45747.1    ATLV01014443    KE524972    KFB38760.1    JXJN01009163    GEFH01001668    JAP66913.1    AXCM01000329    CH477898    EAT35255.1    GGFJ01005973    MBW55114.1    GFAC01000702    JAT98486.1    ADMH02001121    ETN64052.1    GFDF01001275    JAV12809.1    GFDF01005273    JAV08811.1    EZ424199    ADD20475.1    AXCN02001158    OUUW01000001    SPP74995.1    LJIJ01000374    ODM98200.1    AAAB01008880    EAA08515.4    GACK01004718    JAA60316.1    BT080822    ACO15246.1    KK852561    KDR21333.1    APCN01002556    GADI01002739    JAA71069.1    GANO01001584    JAB58287.1    KZ288271    PBC29766.1    JR048984    AEY60824.1    GGLE01000821    MBY04947.1    GFWV01018565    MAA43293.1    GDIQ01190268    JAK61457.1    GDIQ01140540    JAL11186.1    GDIQ01225852    JAK25873.1    GDIP01022172    JAM81543.1    GDIQ01222057    JAK29668.1    GDIQ01206664    JAK45061.1    CM000071    EDY69477.1    CH479210    EDW32920.1    GDIQ01216008    JAK35717.1    GDIQ01098149    JAL53577.1    GL732605    EFX71867.1    GALX01004621    JAB63845.1    GDIQ01224700    JAK27025.1    GDIQ01047870    JAN46867.1    GDIQ01216007    JAK35718.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000053268    UP000283053    UP000000311    + More
UP000215335    UP000002358    UP000095301    UP000053825    UP000019118    UP000030742    UP000007266    UP000053097    UP000279307    UP000095300    UP000007755    UP000002320    UP000283509    UP000036403    UP000037069    UP000009046    UP000008237    UP000076502    UP000054359    UP000091820    UP000005205    UP000075880    UP000069272    UP000030765    UP000092460    UP000075900    UP000075883    UP000008820    UP000075885    UP000092445    UP000000673    UP000075884    UP000078200    UP000075886    UP000268350    UP000094527    UP000075920    UP000075902    UP000076408    UP000075903    UP000075882    UP000007062    UP000076407    UP000027135    UP000075840    UP000242457    UP000001819    UP000008744    UP000000305   

PRIDE

H9J1D2    G3MNQ8    L7M7N7   

Pfam

PF00155   Aminotran_1_2

Interpro

IPR015421   PyrdxlP-dep_Trfase_major        + More
IPR015424   PyrdxlP-dep_Trfase       
IPR004839   Aminotransferase_I/II       
IPR000796   Asp_trans       
IPR004838   NHTrfase_class1_PyrdxlP-BS       
IPR015422   PyrdxlP-dep_Trfase_dom1       

SUPFAM

SSF53383   SSF53383       

Gene 3D

3.40.640.10     3.90.1150.10    

ProteinModelPortal

H9J1D2   A0A212ENG7   A0A2A4JUG9   A0A194PKR4   A0A2A4JUS7   S4P8E3   + More
A0A2W1B2Y8   A0A437BNU4   A0A286T886   A0A1B6LUX2   E2AD28   A0A232F6X6   K7J4Q5   A0A1I8MDM9   A0A0L7QQR4   A0A1L8EHE6   J3JZG8   A0A336ME91   A0A139WGX0   D6WLK0   A0A026VVN6   A0A1I8NTS8   F4WRA2   A0A1I8NTU3   B0WKE5   G3MNQ8   A0A423U3M3   A0A0J7NT78   A0A0L0CPL8   A0A1B6EGT9   E0VIU2   A0A1Y1LB57   E2BMX0   A0A0T6BEY3   A0A411G7V3   A0A154PH48   V5SI13   A0A023FW59   A0A087UAJ9   A0A1A9W3A5   A0A1Q3FJP1   Q5K6H4   A0A023ERN7   A0A023ESU6   A0A158NUA6   A0A182J070   A0A2M4AD35   A0A286T8E3   A0A182F9E4   A0A084VLB6   A0A1B0B6M6   A0A131XIE3   A0A182RYK7   A0A182MB16   Q16LN3   A0A182PPZ4   A0A1B0A700   A0A2M4BQ28   A0A1E1XHD6   W5JI36   A0A1L8E2F8   A0A182N5Q7   A0A1A9UIE9   A0A1L8DQY1   D3TRZ7   A0A182Q0R3   A0A3B0J1W3   A0A1D2MYX3   A0A182W1K6   A0A182U2L9   A0A182YGL0   A0A182UP30   A0A182L7F0   Q7QB79   L7M7N7   C1C1U3   A0A182XJ05   A0A067RE69   A0A182I7V0   A0A0K8RKI9   U5EW46   A0A2A3EF32   V9IKH9   A0A2R5L684   A0A293MQX8   A0A0P5K381   A0A0P5NY43   A0A0P5HRT9   A0A0P6AZD2   A0A0P5I1C1   A0A0P5J4N6   B5E189   B4H584   A0A0P5IAY4   A0A0P5RQV0   E9H8T5   V5G1F1   A0A0P5HV36   A0A0P6FG42   A0A0P5K316  

PDB

2CST     E-value=1.93691e-140,     Score=1279

KEGG

101736083    K14454 aspartate aminotransferase, cytoplasmic [EC:2.6.1.1] | (RefSeq) aspartate aminotransferase, c

PATHWAY

00220    Arginine biosynthesis - Bombyx mori (domestic silkworm)
00250    Alanine, aspartate and glutamate metabolism - Bombyx mori (domestic silkworm)
00270    Cysteine and methionine metabolism - Bombyx mori (domestic silkworm)
00330    Arginine and proline metabolism - Bombyx mori (domestic silkworm)
00350    Tyrosine metabolism - Bombyx mori (domestic silkworm)
00360    Phenylalanine metabolism - Bombyx mori (domestic silkworm)
00400    Phenylalanine, tyrosine and tryptophan biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
01210    2-Oxocarboxylic acid metabolism - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0030170   GO:0004069   GO:0009058   GO:0006520   GO:0008483   GO:0006532   GO:0005829   GO:0003824   GO:0008270   GO:0003677   GO:0016020   GO:0016876   GO:0043039  

PANTHER

PTHR11879  

Length:

415

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01437

Exp number, first 60 AAs:

0.00017

Total prob of N-in:

0.00814

outside

1  -  415

 

 

Pi

221.199277

Theta

169.517682

Tajima's D

0.98518

CLR

0.528907

CSRT

0.654367281635918

Interpretation

Uncertain