Gene

KWMTBOMO09269

Pre Gene Modal

BGIBMGA003321

Annotation

PREDICTED:_acetylcholinesterase_type_1_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr15(-):14795468-14864484      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

Mitochondrial   Reliability : 1.184

CDS

ATGCGCGTGGTGTTGGCAGCGCTGACGGCGCTGGCGGCGCGCACCCTTGCCGGTCCGCACGAGCACCGGGCGAGGCACCACGCGCCTGCGCCTCCGCAGCCCTACCACGGCCACGGCGAGGCCGTCCGATACAACCCCGAACTCGATACCATTCTACCAAGACTTGAAGACCACGAAACTTCGTCTAAGCGCGCCAGTGATGCGGAAACTTCGTCCAAGAGAACCAAGTATGAGGAGAGATTTTACTCTAATCACGAACGAGCCGCGGAGCTCATGGCCGACGAGCCGGTCTCAGAAAAAGGAGACGAAGAGGATCCCCTAGTTATTCGCACTAGGAAGGGAAAGGTGAGAGGAATTACGCTGACTTCAGCAACTGGAAAGAAAGTCGATGCATGGTTTGGCATCCCTTATGCACAAAAACCTATGGGCGATTTGAGGTTCAGGCACCCGAGACCCGTCGAAGATTGGGGCGATGAAATTCTTAACACAACAACACTGCCACATTCCTGCGTCCAAATAGTTGACACGGTATTCGGTGACTTTCCCGGAGCCATGATGTGGAATCCCAATACAGATATGCAGGAAGATTGTCTTTATATTAACATAGTGACACCTCGACCACGTCCAAAGAATGCTGCGGTTATGTTATGGGTATTTGGAGGAGGCTTTTATTCCGGTACAGCCACTTTAGATGTTTACGACCCAAAAATACTTGTTTCGGAAGAAAAAGTTGTGTATGTGTCCATGCAGTACAGAGTTGCATCACTTGGATTCCTGTTTTTCGATACGGCCGACGTCCCTGGAAATGCTGGGTTATTTGATCAGCTGATGGCATTGCAATGGGTGAAAGATAACATTGGCTATTTTGGAGGGAATCCACACAACATAACATTATTCGGTGAATCAGCGGGAGCCGTGTCAGTGTCGTTACATTTGCTGTCTCCCTTGTCGAGGAACCTGTTCTCTCAAGCTATCATGCAGTCTGGAGCCGCCACTGCTCCATGGGCTATAATTTCGAGAGAAGAAAGTATTCTGCGTGGCATAAGATTGGCTGAAGCTGTCCACTGTCCACATTCAAGATCGGATTTGGCTCCTATGATAGAATGCTTGCGAAAAAAGAATGCGGATGAATTGGTTAATAATGAGTGGGGGACATTGGGTATATGTGAATTTCCGTTTGTTCCTATCATCGATGGATCGTTTCTGGATGAGATGCCGGTAAGGTCGTTAGCTCATCAAAACTTTAAGAAAACAAATATTCTTATGGGATCCAATACCGAAGAAGGATATTATTTTATACTCTATTACCTAACTGAATTGTTTCCAAAAGAGGAGAACGTTGGAATTAGCCGGGAACAGTTTCTTCAAGCAGTGAGAGAACTCAATCCGTATGTTAACGACGTAGCAAGGCAGGCTATCATATACGAGTACACTGATTGGTTGAATCCTGAAGATCCGGTAAAGAATCGCAACGCTCTCGACAAAATGGTCGGAGACTATCATTTCACTTGTGGAGTAAACGAATTTGCCCATCGTTATGCAGAAACTGGTAATAATGTTTACACTTATTATTACAAGCATCGTAGTAAGAATAACCCTTGGCCGTCCTGGACTGGTGTGATGCATGCTGACGAGATAAACTATGTGTTCGGGGAGCCTCTCAATCCCGGGAAAAATTATTCGCCGGAAGAAGTCGAATTCAGCAAACGCTTAATGAGATATTGGGCAAACTTCGCTAGATCTGGAAATCCGTCTCTGAATCCAAACGGCGAAATGACGAAGATACATTGGCCGGTTCACACGGCCTTTGGACGGGAATATTTATCACTGGCTGTGAACTCCAGTTCAGTTGGTCGTGGTCTACGCGTTAAACAGTGCGCTTTTTGGCAGAAACATCTCCCCCAGTTAATGGCTGCTACCAATAAACCAGAGCCGCCGAAGAATTGTACGAATTCTGTTTCTTCTTTGTGGCCATCTCGCAAAGCTCTCGGCTTCAACGTCATAGCAACCGCTGCGCTTACAGGCACAGCACTGTTCAAATACACCATATAA

Protein

MRVVLAALTALAARTLAGPHEHRARHHAPAPPQPYHGHGEAVRYNPELDTILPRLEDHETSSKRASDAETSSKRTKYEERFYSNHERAAELMADEPVSEKGDEEDPLVIRTRKGKVRGITLTSATGKKVDAWFGIPYAQKPMGDLRFRHPRPVEDWGDEILNTTTLPHSCVQIVDTVFGDFPGAMMWNPNTDMQEDCLYINIVTPRPRPKNAAVMLWVFGGGFYSGTATLDVYDPKILVSEEKVVYVSMQYRVASLGFLFFDTADVPGNAGLFDQLMALQWVKDNIGYFGGNPHNITLFGESAGAVSVSLHLLSPLSRNLFSQAIMQSGAATAPWAIISREESILRGIRLAEAVHCPHSRSDLAPMIECLRKKNADELVNNEWGTLGICEFPFVPIIDGSFLDEMPVRSLAHQNFKKTNILMGSNTEEGYYFILYYLTELFPKEENVGISREQFLQAVRELNPYVNDVARQAIIYEYTDWLNPEDPVKNRNALDKMVGDYHFTCGVNEFAHRYAETGNNVYTYYYKHRSKNNPWPSWTGVMHADEINYVFGEPLNPGKNYSPEEVEFSKRLMRYWANFARSGNPSLNPNGEMTKIHWPVHTAFGREYLSLAVNSSSVGRGLRVKQCAFWQKHLPQLMAATNKPEPPKNCTNSVSSLWPSRKALGFNVIATAALTGTALFKYTI

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

B0FGT1   A2IBS5   B8YJN6   Q2Q5Z2   Q08LY8   A0A2A4JFX4   + More
G1CRK2   A0A2H1VH42   A0A194PLI1   A0A1B1T6F9   A0A1S5YCY2   A0A194RP51   A0A1D8QQF7   J7EI43   Q2XQ03   Q2XQ02   A0A385HWF0   A0A1U9X205   A0A3S2NNB5   A0A0G3VFZ6   A0A076VEW9   Q1PSX2   A5HBN8   Q4PNK9   I1VRJ7   I1VRJ6   Q1X860   A0A218KFK3   A0A212FJB0   A0A0L7L4Y1   Q5S579   C0KYM8   D2KI31   D2KI32   D2KI33   A0A0B4RY90   A0A166AI58   B6D7G8   Q2PZG3   D2KTD9   D2KTD8   D2KTI7   A1KXE8   D2KTE2   D2KTJ9   D2KTF3   D2KTF2   D2KTI9   D2KTK3   A0A1B6MCT5   A0A1B6JWT5   D6WLS4   E0W5T8   D2KTH8   E7DN61   A0A1L1ZYE6   A0A1Y1K2U2   D2KHI7   A0A1L2FU40   E0VWQ5   A2PZ97   R9THA4   A0A1B6EAZ3   A0A224XLV2   A0A1W4WGF8   A0A023F5Z0   A0A1W4WHR2   A0A067R283   A2PZ99   V9NDA4   T1H8Y3   A0A0P4VRY1   F8TTP2   N6UMQ8   G9BJC1   G3LUX3   B3SST4   B3SST3   H9BIC5   U4TW34   A0A158NS84   A0A348G666   A0A2R2V0F5   A0A151JAS6   X5BGI7   A0A151JVH6   A0A0A9YZC7   A0A0H4AC10   A0A0H4A786   A0A1I7PJ29   A0A195BQW2   E2B493   A0A2A3EL19   A0A087ZWF0   E2AXR7   A0A3L8DK07   A0A026WHR6   A0A2P8ZHI6  

EC Number

3.1.1.-

Pubmed

19121390    26354079    28111266    16876707    30184214    26470257    + More
16352398    19028456    25732547    17196934    22118469    26227816    20385234    16907838    18362917    19820115    28004739    20566863    17294923    25474469    24845553    27129103    21689750    23537049    22280344    22136067    18721883    21347285    25401762    26823975    27521910    20798317    30249741    24508170    29403074   

EMBL

BABH01023917    EU328261    ABY50088.1    EF190220    EU262633    ABM66370.1    + More
ABW96133.1    FJ542315    ACL80033.1    DQ186605    DQ186606    ABB05342.1    AB189740    BAF33338.1    NWSH01001727    PCG70330.1    JF894118    AEK27379.1    ODYU01002526    SOQ40136.1    KQ459602    KPI93589.1    KU578043    ANV77896.1    KY130418    AQQ79918.1    KQ460106    KPJ17801.1    KT893313    AOW44163.1    GQ489250    ADM83588.1    DQ267977    ABB76666.1    DQ267978    ABB76667.1    MH105065    AXY55123.1    KY021891    AQY62780.1    RSAL01000026    RVE52051.1    KP657634    AKL78859.1    KF574430    AIK27530.1    DQ001323    AAY42136.1    EF453724    ABO38111.1    DQ064790    AAY59530.1    JQ085429    AFI47643.1    JQ085428    AFI47642.1    AY970293    AAY34743.1    KU985167    ANB32500.1    AGBW02008289    OWR53828.1    JTDY01003004    KOB70329.1    AY773014    AAV65825.2    FJ647185    ACN78619.1    GU214754    ADA60183.1    GU214755    ADA60184.1    GU214756    ADA60185.1    KJ023221    AIY69049.1    KU060811    AMZ80113.1    EU854149    ACI16651.2    DQ288249    ABB89946.1    AB264371    AB264372    AB264373    AB264375    AB264376    AB264377    AB264378    AB264379    AB264391    AB264392    AB264393    AB264413    AB264414    AB264415    AB264416    AB264417    AB264418    AB264420    AB264430    AB264432    AB264433    AB264439    AB264442    AB264443    AB264444    AB264445    AB264448    BAI63644.1    BAI63686.1    BAI63687.1    BAI63688.1    BAI63689.1    BAI63690.1    BAI63691.1    BAI63693.1    BAI63703.1    BAI63705.1    BAI63706.1    BAI63712.1    BAI63715.1    BAI63716.1    BAI63717.1    BAI63718.1    BAI63721.1    AB264370    BAI63643.1    AB264419    BAI63692.1    AY256851    AB264380    AB264381    AB264382    AB264383    AB264386    AB264387    AB264389    AB264390    AB264394    AB264395    AB264396    AB264397    AB264398    AB264402    AB264403    AB264404    AB264405    AB264406    AB264407    AB264408    AB264412    AB264423    AB264424    AB264425    AB264426    AB264427    AB264440    AB264441    AAP87381.1    BAI63653.1    BAI63667.1    BAI63675.1    BAI63676.1    BAI63677.1    BAI63678.1    BAI63679.1    BAI63680.1    BAI63681.1    BAI63685.1    BAI63696.1    BAI63697.1    BAI63698.1    BAI63699.1    BAI63700.1    BAI63713.1    BAI63714.1    AB264374    BAI63647.1    AB264431    BAI63704.1    AB264385    AB264388    AB264399    AB264400    AB264401    AB264409    AB264411    AB264422    AB264428    AB264429    AB264434    AB264436    AB264437    AB264438    AB264446    AB264447    BAI63658.1    BAI63672.1    BAI63673.1    BAI63674.1    BAI63682.1    BAI63684.1    BAI63695.1    BAI63701.1    BAI63702.1    BAI63707.1    BAI63709.1    BAI63710.1    BAI63711.1    BAI63719.1    BAI63720.1    AB264384    BAI63657.1    AB264421    BAI63694.1    AB264435    BAI63708.1    GEBQ01006278    GEBQ01000321    JAT33699.1    JAT39656.1    GECU01036377    GECU01004067    JAS71329.1    JAT03640.1    KQ971343    EFA04156.1    EU086057    ABX44668.1    AB264410    BAI63683.1    HQ260968    ADU33189.1    KP403801    ALJ52590.1    GEZM01096582    GEZM01096577    GEZM01096575    GEZM01096574    GEZM01096572    GEZM01096571    GEZM01096566    GEZM01096563    GEZM01096560    GEZM01096559    GEZM01096557    GEZM01096555    GEZM01096554    GEZM01096551    GEZM01096550    GEZM01096549    GEZM01096548    GEZM01096547    GEZM01096544    JAV54811.1    GU211888    ADA63843.1    KT779500    AOD74992.1    DS235823    EEB17811.1    AB266606    BAF46105.1    KC493656    AGN31550.1    GEDC01027943    GEDC01002206    JAS09355.1    JAS35092.1    GFTR01007437    JAW08989.1    GBBI01002099    JAC16613.1    KK852751    KDR17140.1    AB266615    BAF46107.1    KC470080    AGN31549.1    ACPB03000401    GDKW01001936    JAI54659.1    JF343436    AEI70751.1    APGK01026066    APGK01026067    APGK01026068    APGK01026069    KB740613    ENN79997.1    HQ605041    ADZ15146.1    JN563927    JQ349158    JQ349159    AEN69455.1    AFA26651.1    EF675188    ABV45413.1    EF675187    ABV45412.1    JQ027700    AFC88123.1    KB631238    KB631239    ERL84183.1    ERL84184.1    ADTU01024676    FX985608    BBF97939.1    KY464935    AQX36216.1    KQ979226    KYN22216.1    KJ174463    AHW29553.1    KQ981688    KYN37905.1    GBHO01006065    GBRD01006315    GBRD01006314    GDHC01016335    GDHC01001232    JAG37539.1    JAG59506.1    JAQ02294.1    JAQ17397.1    KR605107    AKN45955.1    KR605108    AKN45956.1    KT805420    AOS89450.1    KQ976421    KYM89099.1    GL445515    EFN89510.1    KZ288215    PBC32513.1    KU532288    ANT80563.1    GL443653    EFN61766.1    QOIP01000007    RLU20701.1    KK107238    EZA54599.1    PYGN01000056    PSN55962.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000283053    UP000007151    + More
UP000037510    UP000007266    UP000009046    UP000192223    UP000027135    UP000015103    UP000019118    UP000030742    UP000005205    UP000078492    UP000078541    UP000078540    UP000008237    UP000242457    UP000005203    UP000000311    UP000279307    UP000053097    UP000245037   

PRIDE

B0FGT1    Q2Q5Z2    Q08LY8   

Pfam

PF00135   COesterase

Interpro

IPR000997   Cholinesterase        + More
IPR019819   Carboxylesterase_B_CS       
IPR029058   AB_hydrolase       
IPR019826   Carboxylesterase_B_AS       
IPR002018   CarbesteraseB       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

B0FGT1   A2IBS5   B8YJN6   Q2Q5Z2   Q08LY8   A0A2A4JFX4   + More
G1CRK2   A0A2H1VH42   A0A194PLI1   A0A1B1T6F9   A0A1S5YCY2   A0A194RP51   A0A1D8QQF7   J7EI43   Q2XQ03   Q2XQ02   A0A385HWF0   A0A1U9X205   A0A3S2NNB5   A0A0G3VFZ6   A0A076VEW9   Q1PSX2   A5HBN8   Q4PNK9   I1VRJ7   I1VRJ6   Q1X860   A0A218KFK3   A0A212FJB0   A0A0L7L4Y1   Q5S579   C0KYM8   D2KI31   D2KI32   D2KI33   A0A0B4RY90   A0A166AI58   B6D7G8   Q2PZG3   D2KTD9   D2KTD8   D2KTI7   A1KXE8   D2KTE2   D2KTJ9   D2KTF3   D2KTF2   D2KTI9   D2KTK3   A0A1B6MCT5   A0A1B6JWT5   D6WLS4   E0W5T8   D2KTH8   E7DN61   A0A1L1ZYE6   A0A1Y1K2U2   D2KHI7   A0A1L2FU40   E0VWQ5   A2PZ97   R9THA4   A0A1B6EAZ3   A0A224XLV2   A0A1W4WGF8   A0A023F5Z0   A0A1W4WHR2   A0A067R283   A2PZ99   V9NDA4   T1H8Y3   A0A0P4VRY1   F8TTP2   N6UMQ8   G9BJC1   G3LUX3   B3SST4   B3SST3   H9BIC5   U4TW34   A0A158NS84   A0A348G666   A0A2R2V0F5   A0A151JAS6   X5BGI7   A0A151JVH6   A0A0A9YZC7   A0A0H4AC10   A0A0H4A786   A0A1I7PJ29   A0A195BQW2   E2B493   A0A2A3EL19   A0A087ZWF0   E2AXR7   A0A3L8DK07   A0A026WHR6   A0A2P8ZHI6  

PDB

5YDJ     E-value=0,     Score=2091

KEGG

692783    K01049 acetylcholinesterase [EC:3.1.1.7] | (RefSeq) ace1, Bmace1, ace2; acetylcholinesterase type 1

PATHWAY

00564    Glycerophospholipid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0004104   GO:0016021   GO:0016787   GO:0003990   GO:0008270   GO:0006508   GO:0000413   GO:0003723   GO:0003677   GO:0016020   GO:0016876   GO:0043039  

SignalP

Position:   1 - 17,         Likelihood:  0.929658

 

 

Length:

683

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.18816

Exp number, first 60 AAs:

0.00427

Total prob of N-in:

0.01875

outside

1  -  683

 

 

Pi

210.87279

Theta

160.471743

Tajima's D

0.60864

CLR

0.778852

CSRT

0.540772961351932

Interpretation

Uncertain