Gene

KWMTBOMO09243  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003414

Annotation

PREDICTED:_peptidyl-prolyl_cis-trans_isomerase_E-like_[Amyelois_transitella]

Location

Bomo_Chr15(+):13920488-13925778      View in EpiBrowser

Full name

Peptidyl-prolyl cis-trans isomerase E       + More
Peptidyl-prolyl cis-trans isomerase      

Location in the cell

Cytoplasmic   Reliability : 3.179

CDS

ATGTCGAGTAAGCCTAATTCTAAGCGGACAATATACGTTGGAGGGCTAGCTGAGGAGGTCGACGAGAAAGTTTTAAACGCTGCTTTCATCCCTTTCGGGGATTTGGTTGATGTTCAAATACCTTTGGATTATGAGACTGAGAAGCATCGGGGCTTCGCTTTCATAGAGTTCGAAAACGCTGAGGATGCTGCCGCAGCGATTGATAACATGAATGATTCAGAACTATTTGGTAGAACAATACGAGTGAACATAGCAGCTCCGCAACGCATTAAAGAAGGCTCCACACGACCTGTCTGGTCGGATGACTCATGGCTGCAGAAACATGCTGGGGAAACTCTTCAACTGAACAAAGATGGTGAAGAAACTGAAACGAAAGACAAAACCGAAACTACTAGTGTCACACCATCGAAACCGATAGAGAAACGCAATCCTCAAGTGTATTTCGACATAAGTGTAAACAAACAAGAAATAGGCCGTATAATTATGATGCTTCGAGCCGACATAGTCCCAAAAACAGCGGAGAACTTTCGATCTTTGTGTACACACGAGAAAGGTTTCGGTTACCAGGGCAGTAGCTTTCATCGAATCATTCCAGAATTCATGTGTCAAGGAGGAGACTTCACGAATCACAACGGAACTGGGGGAAAGTCTATATACGGCAGAAAATTTGAAGATGAAAACTTCGCATTAAAACACACCGGCCCCGGGGTTCTAAGTATGGCTAATTCCGGACCCAACTCGAATGGATCACAATTCTTTCTTTGTACTGCAAAAACAGAATGGTTGGACGGTAAGCACGTGGTTTTCGGTCACGTGATCTCCGGCTTGGACGTGATGAAGAAGATGGAGAGGTACGGCAGTAAGAGCGGAACGGTTTCAGCGAAAGTTGTCATAAGTAATTGTGGAGAATTACAATGA

Protein

MSSKPNSKRTIYVGGLAEEVDEKVLNAAFIPFGDLVDVQIPLDYETEKHRGFAFIEFENAEDAAAAIDNMNDSELFGRTIRVNIAAPQRIKEGSTRPVWSDDSWLQKHAGETLQLNKDGEETETKDKTETTSVTPSKPIEKRNPQVYFDISVNKQEIGRIIMMLRADIVPKTAENFRSLCTHEKGFGYQGSSFHRIIPEFMCQGGDFTNHNGTGGKSIYGRKFEDENFALKHTGPGVLSMANSGPNSNGSQFFLCTAKTEWLDGKHVVFGHVISGLDVMKKMERYGSKSGTVSAKVVISNCGELQ

Description

Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Similarity

Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
Belongs to the cyclophilin-type PPIase family.

Uniprot

A0A194PJH7   A0A2A4J4L3   A0A212F0X7   A0A212F0T3   A0A2H1VLQ3   E1ZXZ7   + More
A0A0M9A659   A0A3L8D9C2   A0A1W4XM23   A0A0L7QT84   F4WCN7   A0A158NHS7   A0A154NZQ3   A0A088AAK5   A0A2A3E6N6   A0A1B6F4F8   D7EJF5   A0A232EKH6   A0A1B6KG36   A0A1B6CLZ8   A0A1Y1MEQ2   A0A067QNN3   R4G5G7   A0A069DR37   A2I3X9   A0A0P4VRQ5   U4UGH1   A0A293LAS4   A0A146LQE9   S4P2H2   A0A1S3HFU7   A0A023F8R1   A0A1S3HFS1   A0A0A1WHH3   A0A2P8ZAP4   A0A0K8V144   A0A2L2YI73   A0A1E1XBF8   A0A1B0DFA3   A0A182QX19   A0A034WFT1   V5HJA9   A0A131Y2G2   A0A0L0C7I7   A0A182M938   A0A182YDH0   B7PA38   A0A182P323   A0A2M4AU61   A0A2R5LKZ3   A0A182WGP3   L7LSL5   A0A182S9J9   A0A182HEK5   W8B1H8   N6TWX7   A0A224YP20   A0A131Z0D4   A0A182RQ60   A0A1S4FFY8   Q16HQ8   A0A1Z5L9W5   A0A182F1Q4   A0A1A9X3X2   A0A1A9UXH2   A0A195BVP8   A0A1B0CQ73   D3TQF1   A0A195ETV6   W5J768   A0A182NBZ1   A0A0P4VTS8   A0A182TM61   A0A1A9Z7P7   A0A182K6P6   A0A1A9XVZ5   A0A1B0AP37   K1QAU8   A0A182UY93   A0A182XGC3   A0A182KTV4   Q7Q1F8   A0A182HRR1   A0A195DGC6   A0A2S2PY29   A0A1Q3F3L3   A0A1I8MHE0   A7SBW4   H3DHM5   B0WPX5   A0A1I8Q6V0   N6T3T0   B4J6C9   A0A2M3ZBS3   A0A182J3Q2   A0A2H8TT40   A0A034WD65   G3MJT9   A0A2M4BUM4   A0A1V4JHP5  

EC Number

5.2.1.8

Pubmed

26354079    22118469    20798317    30249741    21719571    21347285    + More
18362917    19820115    28648823    28004739    24845553    26334808    27129103    23537049    26823975    23622113    25474469    25830018    29403074    26561354    28503490    25348373    25765539    26108605    25244985    25576852    26483478    24495485    28797301    26830274    17510324    28528879    20353571    20920257    23761445    22992520    20966253    12364791    14747013    17210077    25315136    17615350    15496914    17994087    22216098   

EMBL

KQ459602    KPI93576.1    NWSH01003409    PCG66353.1    AGBW02010997    OWR47406.1    + More
AGBW02011037    OWR47340.1    ODYU01003062    SOQ41362.1    GL435158    EFN73937.1    KQ435727    KOX78035.1    QOIP01000011    RLU16713.1    KQ414755    KOC61779.1    GL888070    EGI68217.1    ADTU01001747    KQ434786    KZC05062.1    KZ288374    PBC26711.1    GECZ01024627    JAS45142.1    DS497704    EFA12724.1    NNAY01003812    OXU18818.1    GEBQ01029545    JAT10432.1    GEDC01022910    GEDC01009477    JAS14388.1    JAS27821.1    GEZM01033286    JAV84282.1    KK853119    KDR11134.1    ACPB03006864    GAHY01000585    JAA76925.1    GBGD01002356    JAC86533.1    EF070482    ABM55548.1    GDKW01000850    JAI55745.1    KB632345    ERL93074.1    GFWV01000764    MAA25494.1    GDHC01009120    JAQ09509.1    GAIX01008491    JAA84069.1    GBBI01000911    JAC17801.1    GBXI01016479    GBXI01000324    JAC97812.1    JAD13968.1    PYGN01000122    PSN53568.1    GDHF01019738    JAI32576.1    IAAA01024323    LAA07864.1    GFAC01002608    JAT96580.1    AJVK01058635    AXCN02000693    GAKP01006329    JAC52623.1    GANP01006779    JAB77689.1    GEFM01003108    JAP72688.1    JRES01000905    KNC27369.1    AXCM01001183    ABJB010240909    DS668983    EEC03460.1    GGFK01010992    MBW44313.1    GGLE01005982    MBY10108.1    GACK01011215    JAA53819.1    JXUM01131986    KQ567784    KXJ69284.1    GAMC01019454    JAB87101.1    APGK01011934    KB738599    ENN82533.1    GFPF01004578    MAA15724.1    GEDV01003664    JAP84893.1    CH478149    EAT33782.1    GFJQ02002890    JAW04080.1    KQ976398    KYM92704.1    AJWK01023182    EZ423653    ADD19929.1    KQ981979    KYN31313.1    KYN31314.1    ADMH02002127    ETN58629.1    GDRN01113669    JAI56723.1    JXJN01001138    JH819021    EKC33872.1    AAAB01008980    EAA14200.3    APCN01001736    KQ980905    KYN11524.1    GGMS01001071    MBY70274.1    GFDL01012912    JAV22133.1    DS469619    EDO38777.1    DS232031    EDS32565.1    APGK01053587    KB741229    ENN72273.1    CH916367    EDW00902.1    GGFM01005246    MBW25997.1    GFXV01005591    MBW17396.1    GAKP01006328    JAC52624.1    JO842140    AEO33757.1    GGFJ01007626    MBW56767.1    LSYS01007350    OPJ71688.1   

Proteomes

UP000053268    UP000218220    UP000007151    UP000000311    UP000053105    UP000279307    + More
UP000192223    UP000053825    UP000007755    UP000005205    UP000076502    UP000005203    UP000242457    UP000007266    UP000215335    UP000027135    UP000015103    UP000030742    UP000085678    UP000245037    UP000092462    UP000075886    UP000037069    UP000075883    UP000076408    UP000001555    UP000075885    UP000075920    UP000075901    UP000069940    UP000249989    UP000019118    UP000075900    UP000008820    UP000069272    UP000091820    UP000078200    UP000078540    UP000092461    UP000078541    UP000000673    UP000075884    UP000075902    UP000092445    UP000075881    UP000092443    UP000092460    UP000005408    UP000075903    UP000076407    UP000075882    UP000007062    UP000075840    UP000078492    UP000095301    UP000001593    UP000007303    UP000002320    UP000095300    UP000001070    UP000075880    UP000190648   

PRIDE

G3MJT9   

Pfam

PF00076   RRM_1        + More
PF00160   Pro_isomerase

Interpro

IPR012677   Nucleotide-bd_a/b_plait_sf        + More
IPR000504   RRM_dom       
IPR002130   Cyclophilin-type_PPIase_dom       
IPR016304   PPIE       
IPR029000   Cyclophilin-like_dom_sf       
IPR020892   Cyclophilin-type_PPIase_CS       
IPR035979   RBD_domain_sf       
IPR034168   PPIE_RRM       
IPR003954   RRM_dom_euk       

SUPFAM

SSF54928   SSF54928        + More
SSF50891   SSF50891       

Gene 3D

2.40.100.10     3.30.70.330    

CDD

cd12347  RRM_PPIE

ProteinModelPortal

A0A194PJH7   A0A2A4J4L3   A0A212F0X7   A0A212F0T3   A0A2H1VLQ3   E1ZXZ7   + More
A0A0M9A659   A0A3L8D9C2   A0A1W4XM23   A0A0L7QT84   F4WCN7   A0A158NHS7   A0A154NZQ3   A0A088AAK5   A0A2A3E6N6   A0A1B6F4F8   D7EJF5   A0A232EKH6   A0A1B6KG36   A0A1B6CLZ8   A0A1Y1MEQ2   A0A067QNN3   R4G5G7   A0A069DR37   A2I3X9   A0A0P4VRQ5   U4UGH1   A0A293LAS4   A0A146LQE9   S4P2H2   A0A1S3HFU7   A0A023F8R1   A0A1S3HFS1   A0A0A1WHH3   A0A2P8ZAP4   A0A0K8V144   A0A2L2YI73   A0A1E1XBF8   A0A1B0DFA3   A0A182QX19   A0A034WFT1   V5HJA9   A0A131Y2G2   A0A0L0C7I7   A0A182M938   A0A182YDH0   B7PA38   A0A182P323   A0A2M4AU61   A0A2R5LKZ3   A0A182WGP3   L7LSL5   A0A182S9J9   A0A182HEK5   W8B1H8   N6TWX7   A0A224YP20   A0A131Z0D4   A0A182RQ60   A0A1S4FFY8   Q16HQ8   A0A1Z5L9W5   A0A182F1Q4   A0A1A9X3X2   A0A1A9UXH2   A0A195BVP8   A0A1B0CQ73   D3TQF1   A0A195ETV6   W5J768   A0A182NBZ1   A0A0P4VTS8   A0A182TM61   A0A1A9Z7P7   A0A182K6P6   A0A1A9XVZ5   A0A1B0AP37   K1QAU8   A0A182UY93   A0A182XGC3   A0A182KTV4   Q7Q1F8   A0A182HRR1   A0A195DGC6   A0A2S2PY29   A0A1Q3F3L3   A0A1I8MHE0   A7SBW4   H3DHM5   B0WPX5   A0A1I8Q6V0   N6T3T0   B4J6C9   A0A2M3ZBS3   A0A182J3Q2   A0A2H8TT40   A0A034WD65   G3MJT9   A0A2M4BUM4   A0A1V4JHP5  

PDB

6ID1     E-value=1.89829e-110,     Score=1019

KEGG

101746413    K09564 peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8] | (RefSeq) peptidyl-prolyl cis-trans

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)

GO

GO:0003755   GO:0006457   GO:0003723   GO:0016018   GO:0042026   GO:0051082   GO:0000974   GO:0000166   GO:0003676   GO:0000413   GO:0003677   GO:0016020   GO:0016876   GO:0043039  

Length:

305

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00157

Exp number, first 60 AAs:

0.00089

Total prob of N-in:

0.09100

outside

1  -  305

 

 

Pi

321.934956

Theta

185.425565

Tajima's D

2.239496

CLR

0.008315

CSRT

0.913404329783511

Interpretation

Uncertain