SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO09184  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA003391
Annotation
DnaJ_domain-containing_protein_[Bombyx_mori]
Full name
Mitochondrial import inner membrane translocase subunit TIM14      
Location in the cell
Mitochondrial   Reliability : 1.527 Nuclear   Reliability : 1.038
 

Sequence

CDS
ATGGCTAGCTCAATAATTCTGGCAGGTCTTGGTATGGCAGCGGTCGGTTTCGCCGGACGATATGTTCTAAAGCAAATGCCAAACGCTTCAATGAAATTTGCCGAAGCAGTGAAGAATTTACCTAAATTCGACTCTGAAACATTAGCAAATTCTAAATATTACAAAGGTGGATTTGAACCAAAAATGACGAAAAGGGAAGCGGCTCTTATTTTAGGCGTAAGCCCCACAGCCAGTAAAGCTAAGATTCGAGATGCTCACCGTAAAATAATGCTATTAAATCATCCTGATAGGGGTGGGTCACCCCTCATAGCAGCAAAGATCAATGAAGCTAAAGATCTACTTGAAAGTGGAAAATCATAG
Protein
MASSIILAGLGMAAVGFAGRYVLKQMPNASMKFAEAVKNLPKFDSETLANSKYYKGGFEPKMTKREAALILGVSPTASKAKIRDAHRKIMLLNHPDRGGSPLIAAKINEAKDLLESGKS

Summary

Description
Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).
Subunit
Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, Roe1, TIM44, blp/TIM16 and TIM14.
Similarity
Belongs to the TIM14 family.
Keywords
Chaperone   Complete proteome   Membrane   Mitochondrion   Mitochondrion inner membrane   Protein transport   Reference proteome   Translocation   Transmembrane   Transmembrane helix   Transport  
Feature
chain  Mitochondrial import inner membrane translocase subunit TIM14
EMBL
DQ311159    ABD36104.1    BABH01023735    RSAL01000300    RVE42764.1    NWSH01001138    + More
PCG72434.1    KQ459602    KPI93521.1    GAIX01012410    JAA80150.1    ODYU01001202    SOQ37097.1    JTDY01006289    KOB66137.1    KQ460615    KPJ13781.1    AK403580    BAM19800.1    KOB66138.1    AGBW02011215    OWR47025.1    UFQT01000429    SSX24225.1    AJWK01030434    CH940647    KRF85194.1    CCAG010003862    JXJN01000881    CH963847    EDW72748.1    GFDF01001665    JAV12419.1    AXCN02000234    CP012525    ALC44311.1    CH902618    KPU78011.1    GFDG01001886    JAV16913.1    GGFL01014797    MBW78975.1    CVRI01000065    CRL05696.1    GGFL01014727    MBW78905.1    EDW70927.1    GGFJ01010818    MBW59959.1    CH933809    KRG06590.1    GGFM01006034    MBW26785.1    EDV39355.1    CM002912    KMY98997.1    CM000159    KRK01670.1    GGFK01009956    MBW43277.1    GBXI01001704    JAD12588.1    AXCM01003571    GGFJ01010726    MBW59867.1    OUUW01000002    SPP77083.1    GAMC01009669    JAB96886.1    KRG06591.1    EDW94144.1    CM000363    EDX10088.1    KMY98996.1    CH379069    KRT08248.1    EDW19308.1    GBYB01001430    JAG71197.1    GDHF01024523    JAI27791.1    AE014296    KX532056    AFH04388.1    ANY27866.1    AY071438    EZ424285    ADD20561.1    CH480815    EDW41112.1    CH916366    EDV97091.1    CH479199    EDW29403.1    EAL29648.2    GEDC01027630    JAS09668.1    GFDL01007165    JAV27880.1    APCN01005495    AAAB01008888    EAA08841.5    KK852901    KDR14095.1    ACL83288.1    GAMD01002361    JAA99229.1    GGFK01011569    MBW44890.1    JRES01000903    KNC27376.1    NNAY01000700    OXU26912.1    KQ434809    KZC06486.1    KQ971342    EFA03031.1    CH954178    KQS43800.1    GEZM01014997    JAV91937.1    GANO01000865    JAB59006.1    GECU01015991    GECU01000043    JAS91715.1    JAT07664.1    GL436519    EFN71865.1    EDV51426.1    GALA01000159    JAA94693.1    GDKW01001624    JAI54971.1    GECZ01012803    JAS56966.1    ACPB03008068    GBHO01026214    GBRD01013034    GDHC01011453    JAG17390.1    JAG52792.1    JAQ07176.1    KZ288305    PBC28780.1    KQ982612    KYQ53863.1    ADTU01017495    LJIJ01000387    ODM98040.1    KQ976453    KYM85437.1    QCYY01001445    ROT78036.1    GEBQ01018492    JAT21485.1   
Pfam
PF00226   DnaJ        + More
PF01221   Dynein_light
Interpro
IPR036869   J_dom_sf        + More
IPR001623   DnaJ_domain       
IPR001372   Dynein_light_chain_typ-1/2       
IPR037177   DLC_sf       
SUPFAM
SSF46565   SSF46565        + More
SSF54648   SSF54648       
Gene 3D
PDB
2GUZ     E-value=3.12927e-14,     Score=184

Ontologies

Topology

Subcellular location
Mitochondrion inner membrane  
Length:
119
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
19.07473
Exp number, first 60 AAs:
19.07349
Total prob of N-in:
0.06953
POSSIBLE N-term signal
sequence
outside
1  -  3
TMhelix
4  -  23
inside
24  -  119
 
 

Population Genetic Test Statistics

Pi
276.623909
Theta
216.16228
Tajima's D
1.0941
CLR
0.358737
CSRT
0.683915804209789
Interpretation
Uncertain
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